CCL2 released at tumoral level contributes to the hyperalgesia evoked by intratibial inoculation of NCTC 2472 but not B16-F10 cells in mice

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 385, Issue 11, 2012, Pages 1053-1061

  Pevida, Marta ^a   González Rodríguez, Sara ^a   Lastra, Ana ^a   Hidalgo, Agustín ^a   Menéndez, Luis ^a   Baamonde, Ana ^a  

^a UNIVERSIDAD DE OVIEDO   (Spain)

Author keywords

Allodynia; Bone cancer induced pain; CCL2; CCR2 antagonists; Hyperalgesia; Mouse; NCTC 2472 cells

Indexed keywords

CHEMOKINE RECEPTOR CCR2 ANTAGONIST; MONOCYTE CHEMOTACTIC PROTEIN 1; RS 504393; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER PAIN; CONTROLLED STUDY; DRUG INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HYPERALGESIA; INOCULATION; MALE; MOUSE; NOCICEPTION; NONHUMAN;

ANIMALS; BENZOXAZINES; BONE NEOPLASMS; CELL LINE, TUMOR; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROSARCOMA; HYPERALGESIA; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; RECEPTORS, CCR2; SPIRO COMPOUNDS; TIBIA;

EID: 84867848784     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-012-0787-2     Document Type: Article

References (35)

1. Abbadie C, Lindia JA, Cumiskey AM, Peterson LB, Mudgett JS, Bayne EK, DeMartino JA, MacIntyre DE, Forrest MJ (2003) Impaired neuropathic pain responses in mice lacking the chemokine receptor CCR2. Proc Natl Acad Sci USA 100:7947-7952
2. Abbadie C, Bhangoo S, De Koninck Y, Malcangio M, Melik-Parsadaniantz S, White FA (2009) Chemokines and pain mechanisms. Brain Res Rev 60:125-134
3. Baamonde A, Curto-Reyes V, Juárez L, Meana A, Hidalgo A, Menéndez L (2007) Antihyperalgesic effects induced by the IL-1 receptor antagonist anakinra and increased IL-1beta levels in inflamed and osteosarcoma-bearing mice. Life Sci 81:673-682
4. Baamonde A, Hidalgo A, Menéndez L (2011) Involvement of glutamate NMDA and AMPA receptors, glial cells and IL-1β in the spinal hyperalgesia evoked by the chemokine CCL2 in mice. Neurosci Lett 502:178-181
5. Belkouch M, Dansereau MA, Réaux-Le Goazigo A, Van Steenwinckel J, Beaudet N, Chraibi A, Melik-Parsadaniantz S, Sarret P (2011) The chemokine CCL2 increases Nav1.8 sodium channel activity in primary sensory neurons through a Gβγ-dependent mechanism. J Neurosci 31:18381-18390
6. Bogen O, Dina OA, Gear RW, Levine JD (2009) Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican. Neuroscience 159:780-786
7. Chaplan SR, Bach FW, Pogrel JW, Chung JM, Yaksh TL (1994) Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Meth 53:55-63
8. Chehl N, Gong Q, Chipitsyna G, Aziz T, Yeo CJ, Arafat HA (2009) Angiotensin II regulates the expression of monocyte chemoattractant protein-1 in pancreatic cancer cells. J Gastrointest Surg 13:2189-2200
9. Constantin CE, Mair N, Sailer CA, Andratsch M, Xu ZZ, Blumer MJ, Scherbakov N, Davis JB, Bluethmann H, Ji RR, Kress M (2008) Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model. J Neurosci 28:5072-5081
10. Curto-Reyes V, Juárez L, García-Pérez E, Fresno MF, Hidalgo A, Menéndez L, Baamonde A (2008) Local loperamide inhibits thermal hyperalgesia but not mechanical allodynia induced by intratibial inoculation of melanoma cells in mice. Cell Mol Neurobiol 28:981-990
11. Curto-Reyes V, Llames S, Hidalgo A, Menéndez L, Baamonde A (2010) Spinal and peripheral analgesic effects of the CB2 cannabinoid receptor agonist AM1241 in two models of bone cancer-induced pain. Br J Pharmacol 160:561-573
12. Dansereau MA, Gosselin RD, Pohl M, Pommier B, Mechighel P, Mauborgne A, Rostene W, Kitabgi P, Beaudet N, Sarret P, Melik-Parsadaniantz S (2008) Spinal CCL2 pronociceptive action is no longer effective in CCR2 receptor antagonist-treated rats. J Neurochem 106:757-769
13. Gao YJ, Zhang L, Samad OA, Suter MR, Yasuhiko K, Xu ZZ, Park JY, Lind AL, Ma Q, Ji RR (2009) JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain. J Neurosci 29:4096-4108
14. Jeon SM, Lee KM, Park ES, Jeon YH, Cho HJ (2008) Monocyte chemoattractant protein-1 immunoreactivity in sensory ganglia and hindpaw after adjuvant injection. Neuroreport 19:183-186
15. Jeon SM, Sung JK, Cho HJ (2011) Expression of monocyte chemoattractant protein-1 and its induction by tumor necrosis factor receptor 1 in sensory neurons in the ventral rhizotomy model of neuropathic pain. Neuroscience 190:354-366
16. Jung H, Toth PT, White FA, Miller RJ (2008) Monocyte chemoattractant protein-1 functions as a neuromodulator in dorsal root ganglia neurons. J Neurochem 104:254-263
17. Khasabova IA, Stucky CL, Harding-Rose C, Eikmeier L, Beitz AJ, Coicou LG, Hanson AE, Simone DA, Seybold VS (2007) Chemical interactions between fibrosarcoma cancer cells and sensory neurons contribute to cancer pain. J Neurosci 27:10289-10298
18. Kim YH, Back SK, Davies AJ, Jeong H, Jo HJ, Chung G, Na HS, Bae YC, Kim SJ, Kim JS, Jung SJ, Oh SB (2012) TRPV1 in GABAergic interneurons mediates neuropathic mechanical allodynia and disinhibition of the nociceptive circuitry in the spinal cord. Neuron 74:640-647
19. Li L, Dragulev B, Zigrino P, Mauch C, Fox JW (2009) The invasive potential of human melanoma cell lines correlates with their ability to alter fibroblast gene expression in vitro and the stromal microenvironment in vivo. Int J Cancer 25:1796-1804
20. Menéndez L, Lastra A, Fresno MF, Llames S, Meana A, Hidalgo A, Baamonde A (2003) Initial thermal heat hypoalgesia and delayed hyperalgesia in a murine model of bone cancer pain. Brain Res 969:102-109
21. Menéndez L, Lastra A, Meana A, Hidalgo A, Baamonde A (2005) Analgesic effects of loperamide in bone cancer pain in mice. Pharmacol Biochem Behav 81:114-121
22. Mirzadegan T, Diehl F, Ebi B, Bhakta S, Polsky I, McCarley D, Mulkins M, Weatherhead GS, Lapierre JM, Dankwardt J, Morgans D Jr, Wilhelm R, Jarnagin K (2000) Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists. J Biol Chem 275:25562-25571
23. Mueller L, von Seggern L, Schumacher J, Goumas F, Wilms C, Braun F, Broering DC (2010) TNF-alpha similarly induces IL-6 and MCP-1 in fibroblasts from colorectal liver metastases and normal liver fibroblasts. Biochem Biophys Res Commun 397:586-591
24. Ogura N, Satoh K, Akutsu M, Tobe M, Kuyama K, Kuboyama N, Sakamaki H, Kujiraoka H, Kondoh T (2010) MCP-1 production in temporomandibular joint inflammation. J Dent Res 89:1117-1122
25. Owen JL, Torroella-Kouri M, Handel-Fernandez ME, Iragavarapu-Charyulu V (2007) GM-CSF upregulates the expression of CCL2 by T lymphocytes in mammary tumor-bearing mice. Int J Mol Med 20:129-136
26. Qin X, Wan Y, Wang X (2005) CCL2 and CXCL1 trigger calcitonin gene-related peptide release by exciting primary nociceptive neurons. J Neurosci Res 82:51-62
27. Schiller KR, Zillhardt MR, Alley J, Borjesson DL, Beitz AJ, Mauro LJ (2009) Secretion of MCP-1 and other paracrine factors in a novel tumor-bone coculture model. BMC Cancer 9:45
28. Schweizerhof M, Stösser S, Kurejova M, Njoo C, Gangadharan V, Agarwal N, Schmelz M, Bali KK, Michalski CW, Brugger S, Dickenson A, Simone DA, Kuner R (2009) Hematopoietic colony-stimulating factors mediate tumor-nerve interactions and bone cancer pain. Nat Med 15:802-807
29. Shirotake S, Miyajima A, Kosaka T, Tanaka N, Kikuchi E, Mikami S, Okada Y, Oya M (2012) Regulation of monocyte chemoattractant protein-1 through angiotensin II type 1 receptor in prostate cancer. Am J Pathol 180:1008-1016
30. Soria G, Ofri-Shahak M, Haas I, Yaal-Hahoshen N, Leider-Trejo L, Leibovich-Rivkin T, Weitzenfeld P, Meshel T, Shabtai E, Gutman M, Ben-Baruch A (2011) Inflammatory mediators in breast cancer: coordinated expression of TNFα & IL-1β with CCL2 & CCL5 and effects on epithelial-to-mesenchymal transition. BMC Cancer 11:130
31. Stösser S, Schweizerhof M, Kuner R (2011) Hematopoietic colony-stimulating factors: new players in tumor-nerve interactions. J Mol Med (Berl) 89:321-329
32. Tanaka T, Minami M, Nakagawa T, Satoh M (2004) Enhanced production of monocyte chemoattractant protein-1 in the dorsal root ganglia in a rat model of neuropathic pain: possible involvement in the development of neuropathic pain. Neurosci Res 48:463-469
33. Wang XM, Hamza M, Wu TX, Dionne RA (2009) Upregulation of IL-6, IL-8 and CCL2 gene expression after acute inflammation: correlation to clinical pain. Pain 142:275-283
34. White FA, Bhangoo SK, Miller RJ (2005) Chemokines: integrators of pain and inflammation. Nat Rev Drug Discov 4:834-844
35. Zimmermann M (1983) Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16:109-110