Analgesic effects of loperamide in bone cancer pain in mice

Pharmacology Biochemistry and Behavior

Volumn 81, Issue 1, 2005, Pages 114-121

  Menéndez, Luis ^a   Lastra, Ana ^a   Meana, Álvaro ^a   Hidalgo, Agustín ^a   Baamonde, Ana ^a  

^a DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

Author keywords

Cancer pain; Loperamide; Osteosarcoma; Peripheral opioid receptors

Indexed keywords

17 METHYLNALOXONE; BINALTORPHIMINE; CYPRODIME; LOPERAMIDE; MU OPIATE RECEPTOR; NALTRINDOLE;

ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE CANCER; CANCER PAIN; CONTROLLED STUDY; DRUG EFFECT; HYPERALGESIA; LATENT PERIOD; MOUSE; NECK; NONHUMAN; OSTEOSARCOMA; PRIORITY JOURNAL; THERMAL ANALYSIS; TIBIA;

ANALGESICS; ANIMALS; BONE NEOPLASMS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; LOPERAMIDE; MICE; MICE, INBRED C3H; PAIN; TIME FACTORS;

GARCIA;

EID: 19344364702     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2005.02.007     Document Type: Article

References (40)

1. A. Baamonde, V. Dauge, G. Gacel, and B.P. Roques Systemic administration of (Tyr-D-Ser(O-tert-butyl)-Gly-Phe-Leu-Thr(O-tert-butyl), a highly selective delta opioid agonist, induces mu receptor-mediated analgesia in mice J Pharmacol Exp Ther 257 1991 767 773
2. A. Baamonde, A. Lastra, M. Villazon, J. Bordallo, A. Hidalgo, and L. Menendez Involvement of endogenous endothelins in thermal and mechanical inflammatory hyperalgesia in mice Naunyn-Schmiedeberg's Arch Pharmacol 369 2004 245 251
3. F.J. Brescia, D. Adler, G. Gray, M.A. Ryan, J. Cimino, and R. Mamtani Hospitalized advanced cancer patients: a profile J Pain Symptom Manage 5 1990 221 227
4. D.M. Cain, P.W. Wacnik, M. Turner, G. Wendelschafer-Crabb, W.R. Kennedy, and G.L. Wilcox Functional interactions between tumor and peripheral nerve: changes in excitability and morphology of primary afferent fibers in a murine model of cancer pain J Neurosci 21 2001 9367 9376
5. C.S. Cleeland, R. Gonin, A.K. Hatfield, J.H. Edmonson, R.H. Blum, and J.A. Stewart Pain and its treatment in outpatients with metastatic cancer N Engl J Med 330 1994 592 596
6. D.L. DeHaven-Hudkins, L.C. Burgos, J.A. Cassel, J.D. Daubert, R.N. DeHaven, and E. Mansson Loperamide (ADL 2-1294), an opioid antihyperalgesic agent with peripheral selectivity J Pharmacol Exp Ther 289 1999 494 502
7. T. Donovan-Rodriguez, A.H. Dickenson, and C.E. Urch Superficial dorsal horn neuronal responses and the emergence of behavioural hyperalgesia in a rat model of cancer-induced bone pain Neurosci Lett 360 2004 29 32
8. S.H. Ferreira, B.B. Lorenzetti, A.F. Bristow, and S. Poole Interleukin-1 beta as a potent hyperalgesic agent antagonized by a tripeptide analogue Nature 334 1988 698 700
9. A. Fox, S. Medhurst, J.P. Courade, M. Glatt, J. Dawson, and L. Urban Anti-hyperalgesic activity of the COX-2 inhibitor lumiracoxib in a model of bone cancer pain in the rat Pain 107 2004 33 40
10. P. Honore, S.D. Rogers, M.J. Schwei, J.L. Salak-Johnson, N.M. Luger, and M.C. Sabino Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons Neuroscience 98 2000 585 598
11. S.X. Hou, J.G. Tang, H.S. Chen, and J. Chen Chronic inflammation and compression of the dorsal root contribute to sciatica induced by the intervertebral disc herniation in rats Pain 105 2003 255 264
12. R.R. Ji, Q. Zhang, P.Y. Law, H.H. Low, R. Elde, and T. Hokfelt Expression of mu-, delta-, and kappa-opioid receptor-like immunoreactivities in rat dorsal root ganglia after carrageenan-induced inflammation J Neurosci 15 1995 8156 8166
13. D. Julius, and A.I. Basbaum Molecular mechanisms of nociception Nature 413 2001 203 210
14. L.J. Kehl, D.T. Hamamoto, P.W. Wacnik, D.L. Croft, B.D. Norsted, and G.L. Wilcox A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain Pain 103 2003 175 186
15. T. Lewanowitsch, and R.J. Irvine Naloxone methiodide reverses opioid-induced respiratory depression and analgesia without withdrawal Eur J Pharmacol 445 2002 61 67
16. N.M. Luger, M.A. Sabino, M.J. Schwei, D.B. Mach, J.D. Pomonis, and C.P. Keyser Efficacy of systemic morphine suggests a fundamental difference in the mechanisms that generate bone cancer vs. inflammatory pain Pain 99 2002 397 406
17. J.P. McLaughlin, M. Marton-Popovici, and C. Chavkin Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses J Neurosci 23 2003 5483 5674
18. S.J. Medhurst, K. Walker, M. Bowes, B.L. Kidd, M. Glatt, and M. Muller A rat model of bone cancer pain Pain 96 2002 129 140
19. S.T. Meller, and G.F. Gebhart Spinal mediators of hyperalgesia Drugs 47 Suppl. 5 1994 10 20
20. G.L. Mendes, A.R. Santos, A. Malheiros, V.C. Filho, R.A. Yunes, and J.B. Calixto Assessment of mechanisms involved in antinociception caused by sesquiterpene polygodial J Pharmacol Exp Ther 292 2000 164 172
21. L. Menéndez, A. Lastra, A. Hidalgo, and A. Baamonde Unilateral hot plate test: a simple and sensitive method for detecting central and peripheral hyperalgesia in mice J Neurosci Methods 113 2002 91 97
22. L. Menéndez, A. Lastra, M.F. Fresno, S. Llames, A. Meana, and A. Hidalgo Initial thermal heat hypoalgesia and delayed hyperalgesia in a murine model of bone cancer pain Brain Res 969 2003 102 109
23. L. Menéndez, A. Lastra, A. Hidalgo, A. Meana, E. Garcia, and A. Baamonde Peripheral opioids act as analgesics in bone cancer pain in mice NeuroReport 14 2003 867 869
24. C.M. Peters, T.H. Lindsay, J.D. Pomonis, N.M. Luger, J.R. Ghilardi, and M.A. Sevcik Endothelin and the tumorigenic component of bone cancer pain Neuroscience 126 2004 1043 1052
25. M.A. Sabino, J.R. Ghilardi, J.L. Jongen, C.P. Keyser, N.M. Luger, and D.B. Mach Simultaneous reduction in cancer pain, bone destruction, and tumor growth by selective inhibition of cyclooxygenase-2 Cancer Res 62 2002 7343 7349
26. A.H. Schinkel, E. Wagenaar, C.A. Mol, and L. van Deemter P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs J Clin Invest 97 1996 2517 2524
27. M.J. Schwei, P. Honore, S.D. Rogers, J.L. Salak-Johnson, M.P. Finke, and M.L. Ramnaraine Neurochemical and cellular reorganization of the spinal cord in a murine model of bone cancer pain J Neurosci 19 1999 10886 10897
28. C. Stein Peripheral analgesic actions of opioids J Pain Symptom Manage 6 1991 119 124
29. C. Stein, M.J. Millan, T.S. Shippenberg, K. Peter, and A. Herz Peripheral opioid receptors mediating antinociception in inflammation. Evidence for involvement of mu, delta and kappa receptors J Pharmacol Exp Ther 248 1989 1269 1275
30. C. Stein, M. Schafer, and H. Machelska Attacking pain at its source: new perspectives on opioids Nat Med 9 2003 1003 1008
31. W. Truong, C. Cheng, Q.G. Xu, X.Q. Li, and D.W. Zochodne Mu opioid receptors and analgesia at the site of a peripheral nerve injury Ann Neurol 53 2003 366 375
32. M.E. Turnbach, and A. Randich The effect of spinal and systemic administration of indomethacin on zymosan-induced edema, mechanical hyperalgesia, and thermal hyperalgesia J Pain 2 2001 25 35
33. C.E. Urch, T. Donovan-Rodriguez, and A.H. Dickenson Alterations in dorsal horn neurones in a rat model of cancer-induced bone pain Pain 106 2003 347 356
34. F. Viana, E. de la Pena, and C. Belmonte Specificity of cold thermotransduction is determined by differential ionic channel expression Nat Neurosci 5 2002 254 260
35. P.W. Wacnik, L.J. Eikmeier, T.R. Ruggles, M.L. Ramnaraine, B.K. Walcheck, and A.J. Beitz Functional interactions between tumor and peripheral nerve: morphology, algogen identification, and behavioral characterization of a new murine model of cancer pain J Neurosci 21 2001 9355 9366
36. P.W. Wacnik, L.J. Kehl, T.M. Trempe, M.L. Ramnaraine, A.J. Beitz, and G.L. Wilcox Tumor implantation in mouse humerus evokes movement-related hyperalgesia exceeding that evoked by intramuscular carrageenan Pain 101 2003 175 186
37. K. Walker, S.J. Medhurst, B.L. Kidd, M. Glatt, M. Bowes, and S. Patel Disease modifying and anti-nociceptive effects of the bisphosphonate, zoledronic acid in a model of bone cancer pain Pain 100 2002 219 229
38. C.J. Woolf, American College of Physicians, and American Physiological Society Pain: moving from symptom control toward mechanism-specific pharmacologic management Ann Intern Med 140 2004 441 451
39. M. Wuster, and A. Herz Opiate agonist action of antidiarrheal agents in vitro and in vivo-findings in support for selective action Naunyn-Schmiedeberg's Arch Pharmacol 301 1978 187 194
40. C. Zollner, M.A. Shaqura, C.P. Bopaiah, S. Mousa, C. Stein, and M. Schafer Painful inflammation-induced increase in mu-opioid receptor binding and G-protein coupling in primary afferent neurons Mol Pharmacol 64 2003 202 210