메뉴 건너뛰기




Volumn 24, Issue 2, 2010, Pages 436-446

Pasireotide and octreotide stimulate distinct patterns of sst2A somatostatin receptor phosphorylation

Author keywords

[No Author keywords available]

Indexed keywords

BETA ARRESTIN; G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 3; OCTREOTIDE; PASIREOTIDE; SOMATOSTATIN 14; SOMATOSTATIN RECEPTOR 2; THREONINE;

EID: 75149175187     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2009-0315     Document Type: Article
Times cited : (84)

References (42)
  • 2
    • 29344452504 scopus 로고    scopus 로고
    • Treatment of acromegaly: Future
    • Donangelo I, Melmed S 2005 Treatment of acromegaly: future. Endocrine 28:123-128
    • (2005) Endocrine , vol.28 , pp. 123-128
    • Donangelo, I.1    Melmed, S.2
  • 3
    • 21344464681 scopus 로고    scopus 로고
    • Neuroendocrine tumors of the gastrointestinal tract: Recent advances in molecular genetics, diagnosis, and treatment
    • Oberg K 2005 Neuroendocrine tumors of the gastrointestinal tract: recent advances in molecular genetics, diagnosis, and treatment. Curr Opin Oncol 17:386-391
    • (2005) Curr Opin Oncol , vol.17 , pp. 386-391
    • Oberg, K.1
  • 4
    • 39749102502 scopus 로고    scopus 로고
    • Indium-111-pentetreotide scintigraphy and somatostatin receptor subtype 2 expression: New prognostic factors for malignant well-differentiated endocrine tumors
    • Asnacios A, Courbon F, Rochaix P, Bauvin E, Cances-Lauwers V, Susini C, Schulz S, Boneu A, Guimbaud R, Buscail L 2008 Indium-111-pentetreotide scintigraphy and somatostatin receptor subtype 2 expression: new prognostic factors for malignant well-differentiated endocrine tumors. J Clin Oncol 26:963-970
    • (2008) J Clin Oncol , vol.26 , pp. 963-970
    • Asnacios, A.1    Courbon, F.2    Rochaix, P.3    Bauvin, E.4    Cances-Lauwers, V.5    Susini, C.6    Schulz, S.7    Boneu, A.8    Guimbaud, R.9    Buscail, L.10
  • 8
    • 30944449710 scopus 로고    scopus 로고
    • The role of somatostatin analogs in Cushing's disease
    • van der Hoek J, Lamberts SW, Hofland LJ 2004 The role of somatostatin analogs in Cushing's disease. Pituitary 7:257-264
    • (2004) Pituitary , vol.7 , pp. 257-264
    • van der Hoek, J.1    Lamberts, S.W.2    Hofland, L.J.3
  • 9
    • 0036111856 scopus 로고    scopus 로고
    • SOM230: A novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile
    • Bruns C, Lewis I, Briner U, Meno-Tetang G, Weckbecker G 2002 SOM230: a novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile. Eur J Endocrinol 146:707-716
    • (2002) Eur J Endocrinol , vol.146 , pp. 707-716
    • Bruns, C.1    Lewis, I.2    Briner, U.3    Meno-Tetang, G.4    Weckbecker, G.5
  • 10
    • 0036773070 scopus 로고    scopus 로고
    • SOM230: A new somatostatin peptidomimetic with potent inhibitory effects on the growth hormone/insulin-like growth factor-I axis in rats, primates, and dogs
    • Weckbecker G, Briner U, Lewis I, Bruns C 2002 SOM230: a new somatostatin peptidomimetic with potent inhibitory effects on the growth hormone/insulin-like growth factor-I axis in rats, primates, and dogs. Endocrinology 143:4123-4130
    • (2002) Endocrinology , vol.143 , pp. 4123-4130
    • Weckbecker, G.1    Briner, U.2    Lewis, I.3    Bruns, C.4
  • 11
    • 0038440483 scopus 로고    scopus 로고
    • A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential
    • Lewis I, Bauer W, Albert R, Chandramouli N, Pless J, Weckbecker G, Bruns C 2003 A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential. J Med Chem 46:2334-2344
    • (2003) J Med Chem , vol.46 , pp. 2334-2344
    • Lewis, I.1    Bauer, W.2    Albert, R.3    Chandramouli, N.4    Pless, J.5    Weckbecker, G.6    Bruns, C.7
  • 12
    • 21844451422 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic comparison of a novel multiligand somatostatin analog, SOM230, with octreotide in patients with acromegaly
    • Ma P, Wang Y, van der Hoek J, Nedelman J, Schran H, Tran LL, Lamberts SW 2005 Pharmacokinetic-pharmacodynamic comparison of a novel multiligand somatostatin analog, SOM230, with octreotide in patients with acromegaly. Clin Pharmacol Ther 78:69-80
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 69-80
    • Ma, P.1    Wang, Y.2    van der Hoek, J.3    Nedelman, J.4    Schran, H.5    Tran, L.L.6    Lamberts, S.W.7
  • 17
    • 42749095844 scopus 로고    scopus 로고
    • Preclinical evidences suggest new treatment options for endocrine disorders: Pasireotide (SOM230) and Everolimus (RAD001)
    • Schmid HA 2008 Preclinical evidences suggest new treatment options for endocrine disorders: Pasireotide (SOM230) and Everolimus (RAD001). Ann Endocrinol 69:162-163
    • (2008) Ann Endocrinol , vol.69 , pp. 162-163
    • Schmid, H.A.1
  • 18
    • 6044221565 scopus 로고    scopus 로고
    • Functional activity of the multiligand analog SOM230 at human recombinant somatostatin receptor subtypes supports its usefulness in neuroendocrine tumors
    • Schmid HA, Schoeffter P 2004 Functional activity of the multiligand analog SOM230 at human recombinant somatostatin receptor subtypes supports its usefulness in neuroendocrine tumors. Neuroendocrinology 1(Suppl 80):47-50
    • (2004) Neuroendocrinology , vol.1 , Issue.SUPPL. 80 , pp. 47-50
    • Schmid, H.A.1    Schoeffter, P.2
  • 19
    • 33744982453 scopus 로고    scopus 로고
    • Short- and long-term effects of octreotide and SOM230 on GH, IGF-I, ACTH, corticosterone and ghrelin in rats
    • Schmid HA, Silva AP 2005 Short- and long-term effects of octreotide and SOM230 on GH, IGF-I, ACTH, corticosterone and ghrelin in rats. J Endocrinol Invest 28:28-35
    • (2005) J Endocrinol Invest , vol.28 , pp. 28-35
    • Schmid, H.A.1    Silva, A.P.2
  • 22
    • 59749083610 scopus 로고    scopus 로고
    • Differential effects of octreotide and pasireotide on somatostatin receptor internalization and trafficking in vitro
    • Lesche S, Lehmann D, Nagel F, Schmid HA, Schulz S 2009 Differential effects of octreotide and pasireotide on somatostatin receptor internalization and trafficking in vitro. J Clin Endocrinol Metab 94:654-661
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 654-661
    • Lesche, S.1    Lehmann, D.2    Nagel, F.3    Schmid, H.A.4    Schulz, S.5
  • 23
    • 0037205489 scopus 로고    scopus 로고
    • Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization
    • Pfeiffer M, Koch T, Schröder H, Laugsch M, Höllt V, Schulz S 2002 Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization. J Biol Chem 277:19762-19772
    • (2002) J Biol Chem , vol.277 , pp. 19762-19772
    • Pfeiffer, M.1    Koch, T.2    Schröder, H.3    Laugsch, M.4    Höllt, V.5    Schulz, S.6
  • 24
    • 2442705543 scopus 로고    scopus 로고
    • Differential β-arrestin trafficking and endosomal sorting of somatostatin receptor subtypes
    • Tulipano G, Stumm R, Pfeiffer M, Kreienkamp HJ, Höllt V, Schulz S 2004 Differential β-arrestin trafficking and endosomal sorting of somatostatin receptor subtypes. J Biol Chem 279:21374-21382
    • (2004) J Biol Chem , vol.279 , pp. 21374-21382
    • Tulipano, G.1    Stumm, R.2    Pfeiffer, M.3    Kreienkamp, H.J.4    Höllt, V.5    Schulz, S.6
  • 27
    • 42049083552 scopus 로고    scopus 로고
    • Low levels of raf kinase inhibitory protein in growth hormone-secreting pituitary adenomas correlate with poor response to octreotide treatment
    • Fougner SL, Bollerslev J, Latif F, Hald JK, Lund T, Ramm-Pettersen J, Berg JP 2008 Low levels of raf kinase inhibitory protein in growth hormone-secreting pituitary adenomas correlate with poor response to octreotide treatment. J Clin Endocrinol Metab 93:1211-1216
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 1211-1216
    • Fougner, S.L.1    Bollerslev, J.2    Latif, F.3    Hald, J.K.4    Lund, T.5    Ramm-Pettersen, J.6    Berg, J.P.7
  • 28
    • 0346874333 scopus 로고    scopus 로고
    • Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2
    • Lorenz K, Lohse MJ, Quitterer U 2003 Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2. Nature 426:574-579
    • (2003) Nature , vol.426 , pp. 574-579
    • Lorenz, K.1    Lohse, M.J.2    Quitterer, U.3
  • 29
    • 67349112176 scopus 로고    scopus 로고
    • Somatostatin and dopamine receptors as targets for medical treatment of Cushing's Syndrome
    • de Bruin C, Feelders RA, Lamberts SW, Hofland LJ 2009 Somatostatin and dopamine receptors as targets for medical treatment of Cushing's Syndrome. Rev Endocr Metab Disord 10:91-102
    • (2009) Rev Endocr Metab Disord , vol.10 , pp. 91-102
    • de Bruin, C.1    Feelders, R.A.2    Lamberts, S.W.3    Hofland, L.J.4
  • 30
    • 4444311166 scopus 로고    scopus 로고
    • Morphine induces terminal micro-opioid receptor desensitization by sustained phosphorylation of serine-375
    • Schulz S, Mayer D, Pfeiffer M, Stumm R, Koch T, Höllt V 2004 Morphine induces terminal micro-opioid receptor desensitization by sustained phosphorylation of serine-375. EMBO J 23:3282-3289
    • (2004) EMBO J , vol.23 , pp. 3282-3289
    • Schulz, S.1    Mayer, D.2    Pfeiffer, M.3    Stumm, R.4    Koch, T.5    Höllt, V.6
  • 32
    • 2542423686 scopus 로고    scopus 로고
    • Differential desensitization, receptor phosphorylation, β-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7
    • Kohout TA, Nicholas SL, Perry SJ, Reinhart G, Junger S, Struthers RS 2004 Differential desensitization, receptor phosphorylation, β-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7. J Biol Chem 279:23214-23222
    • (2004) J Biol Chem , vol.279 , pp. 23214-23222
    • Kohout, T.A.1    Nicholas, S.L.2    Perry, S.J.3    Reinhart, G.4    Junger, S.5    Struthers, R.S.6
  • 33
    • 67649856866 scopus 로고    scopus 로고
    • Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
    • Zidar DA, Violin JD, Whalen EJ, Lefkowitz RJ 2009 Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands. Proc Natl Acad Sci USA 106:9649-9654
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9649-9654
    • Zidar, D.A.1    Violin, J.D.2    Whalen, E.J.3    Lefkowitz, R.J.4
  • 34
    • 0035374624 scopus 로고    scopus 로고
    • Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-β-arrestin complexes after receptor endocytosis*
    • Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG 2001 Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-β-arrestin complexes after receptor endocytosis*. J Biol Chem 276:19452-19460
    • (2001) J Biol Chem , vol.276 , pp. 19452-19460
    • Oakley, R.H.1    Laporte, S.A.2    Holt, J.A.3    Barak, L.S.4    Caron, M.G.5
  • 35
    • 0034595860 scopus 로고    scopus 로고
    • Differential affinities of visual arrestin, β arrestin1, and β arrestin2 for G protein-coupled receptors delineate two major classes of receptors
    • Oakley RH, Laporte SA, Holt JA, Caron MG, Barak LS 2000 Differential affinities of visual arrestin, β arrestin1, and β arrestin2 for G protein-coupled receptors delineate two major classes of receptors. J Biol Chem 275:17201-17210
    • (2000) J Biol Chem , vol.275 , pp. 17201-17210
    • Oakley, R.H.1    Laporte, S.A.2    Holt, J.A.3    Caron, M.G.4    Barak, L.S.5
  • 36
    • 4143070533 scopus 로고    scopus 로고
    • Differential kinetic and spatial patterns of β-arrestin and G protein-mediated ERK activation by the angiotensin II receptor
    • Ahn S, Shenoy SK, Wei H, Lefkowitz RJ 2004 Differential kinetic and spatial patterns of β-arrestin and G protein-mediated ERK activation by the angiotensin II receptor. J Biol Chem 279:35518-35525
    • (2004) J Biol Chem , vol.279 , pp. 35518-35525
    • Ahn, S.1    Shenoy, S.K.2    Wei, H.3    Lefkowitz, R.J.4
  • 37
    • 17644402459 scopus 로고    scopus 로고
    • Transduction of receptor signals by β-arrestins
    • Lefkowitz RJ, Shenoy SK 2005 Transduction of receptor signals by β-arrestins. Science 308:512-517
    • (2005) Science , vol.308 , pp. 512-517
    • Lefkowitz, R.J.1    Shenoy, S.K.2
  • 38
    • 57349142534 scopus 로고    scopus 로고
    • Reassessment of sst2 somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-1
    • Fischer T, Doll C, Jacobs S, Kolodziej A, Stumm R, Schulz S 2008 Reassessment of sst2 somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-1. J Clin Endocrinol Metab 93:4519-4524
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 4519-4524
    • Fischer, T.1    Doll, C.2    Jacobs, S.3    Kolodziej, A.4    Stumm, R.5    Schulz, S.6
  • 40
    • 0344442675 scopus 로고    scopus 로고
    • Somatostatin receptor subtypes in human pheochromocytoma: Subcellular expression pattern and functional relevance for octreotide scintigraphy
    • Mundschenk J, Unger N, Schulz S, Höllt V, Schulz S, Steinke R, Lehnert H 2003 Somatostatin receptor subtypes in human pheochromocytoma: subcellular expression pattern and functional relevance for octreotide scintigraphy. J Clin Endocrinol Metab 88:5150-5157
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5150-5157
    • Mundschenk, J.1    Unger, N.2    Schulz, S.3    Höllt, V.4    Schulz, S.5    Steinke, R.6    Lehnert, H.7
  • 42
    • 13444270337 scopus 로고    scopus 로고
    • Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
    • Ren XR, Reiter E, Ahn S, Kim J, Chen W, Lefkowitz RJ 2005 Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor. Proc Natl Acad Sci USA 102:1448-1453
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1448-1453
    • Ren, X.R.1    Reiter, E.2    Ahn, S.3    Kim, J.4    Chen, W.5    Lefkowitz, R.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.