Increased expression of the glucose-responsive gene, RCAN1, causes hypoinsulinemia, β-cell dysfunction, and diabetes

Endocrinology

Volumn 153, Issue 11, 2012, Pages 5212-5221

  Peiris, Heshan ^a   Raghupathi, Ravinarayan ^a   Jessup, Claire F ^a,b   Zanin, Mark P ^a   Mohanasundaram, Daisy ^b,c   Mackenzie, Kimberly D ^a   Chataway, Tim ^a   Clarke, Jennifer N ^a   Brealey, John ^c   Coates, P Toby ^b,c   Pritchard, Melanie A ^d   Keating, Damien J ^a  

^a FLINDERS UNIVERSITY   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^d MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN INHIBITOR; GLUCOSE; INSULIN; REACTIVE OXYGEN METABOLITE; REGULATOR OF CALCINEURIN 1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL LOSS; CONTROLLED STUDY; CYTOSOL; DIABETES MELLITUS; DOWN REGULATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; GLUCOSE TOLERANCE; HYPERGLYCEMIA; HYPOINSULINEMIA; INSULIN RELEASE; MALE; MITOCHONDRION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION;

ANIMALS; DIABETES MELLITUS; GLUCOSE INTOLERANCE; HYPERGLYCEMIA; INSULIN; INSULIN-SECRETING CELLS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MITOCHONDRIA; MUSCLE PROTEINS; REACTIVE OXYGEN SPECIES;

EID: 84867795201     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-2149     Document Type: Article

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