-
1
-
-
33745541232
-
The epidemiology of inflammatory bowel disease in Canada: A population-based study
-
Bernstein CN, Wajda A, Svenson LW, MacKenzie A, Koehoorn M, Jackson M et al. The epidemiology of inflammatory bowel disease in Canada: a population-based study. Am J Gastroenterol 2006; 101: 1559-1568.
-
(2006)
Am J Gastroenterol
, vol.101
, pp. 1559-1568
-
-
Bernstein, C.N.1
Wajda, A.2
Svenson, L.W.3
MacKenzie, A.4
Koehoorn, M.5
Jackson, M.6
-
2
-
-
36549001139
-
The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States
-
Kappelman MD, Rifas-Shiman SL, Kleinman K, Ollendorf D, Bousvaros A, Grand RJ et al. The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States. Clin Gastroenterol Hepatol 2007; 5: 1424-1429.
-
(2007)
Clin Gastroenterol Hepatol
, vol.5
, pp. 1424-1429
-
-
Kappelman, M.D.1
Rifas-Shiman, S.L.2
Kleinman, K.3
Ollendorf, D.4
Bousvaros, A.5
Grand, R.J.6
-
3
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007; 39: 596-604.
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
Huett, A.6
-
4
-
-
34347338690
-
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
-
Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA et al. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet 2007; 39: 830-832.
-
(2007)
Nat Genet
, vol.39
, pp. 830-832
-
-
Parkes, M.1
Barrett, J.C.2
Prescott, N.J.3
Tremelling, M.4
Anderson, C.A.5
Fisher, S.A.6
-
5
-
-
34247566585
-
A non-synonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5
-
Prescott NJ, Fisher SA, Franke A, Hampe J, Onnie CM, Soars D et al. A non-synonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5. Gastroenterology 2007; 132: 1665-1671.
-
(2007)
Gastroenterology
, vol.132
, pp. 1665-1671
-
-
Prescott, N.J.1
Fisher, S.A.2
Franke, A.3
Hampe, J.4
Onnie, C.M.5
Soars, D.6
-
6
-
-
40949096976
-
Association between genetic variants in the IL-23R gene and early-onset Crohn's disease: Results from a case-control and family-based study among Canadian children
-
Amre DK, Mack D, Israel D, Morgan K, Lambrette P, Law L et al. Association between genetic variants in the IL-23R gene and early-onset Crohn's disease: results from a case-control and family-based study among Canadian children. Am J Gastroenterol 2008; 103: 615-620.
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 615-620
-
-
Amre, D.K.1
MacK, D.2
Israel, D.3
Morgan, K.4
Lambrette, P.5
Law, L.6
-
7
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet 2010; 42: 1118-1125.
-
(2010)
Nat Genet
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
Wang, K.4
Radford-Smith, G.L.5
Ahmad, T.6
-
8
-
-
80054975975
-
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease
-
Rivas MA, Beaudoin M, Gardet A, Stevens C, Sharma Y, Zhang CK et al. Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease. Nat Genet 2011; 43: 1066-1073.
-
(2011)
Nat Genet
, vol.43
, pp. 1066-1073
-
-
Rivas, M.A.1
Beaudoin, M.2
Gardet, A.3
Stevens, C.4
Sharma, Y.5
Zhang, C.K.6
-
9
-
-
0025690311
-
Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily
-
Sladek FM, Zhong WM, Lai E, Darnell Jr JE. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev 1990; 4: 2353-2365.
-
(1990)
Genes Dev
, vol.4
, pp. 2353-2365
-
-
Sladek, F.M.1
Zhong, W.M.2
Lai, E.3
Darnell Jr., J.E.4
-
10
-
-
0028021033
-
Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis
-
Taraviras S, Monaghan AP, Schutz G, Kelsey G. Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis. Mech Dev 1994; 48: 67-79.
-
(1994)
Mech Dev
, vol.48
, pp. 67-79
-
-
Taraviras, S.1
Monaghan, A.P.2
Schutz, G.3
Kelsey, G.4
-
11
-
-
0028246642
-
Expression of the L-type pyruvate kinase gene and the hepatocyte nuclear factor 4 transcription factor in exocrine and endocrine pancreas
-
Miquerol L, Lopez S, Cartier N, Tulliez M, Raymondjean M, Kahn A. Expression of the L-type pyruvate kinase gene and the hepatocyte nuclear factor 4 transcription factor in exocrine and endocrine pancreas. J Biol Chem 1994; 269: 8944-8951.
-
(1994)
J Biol Chem
, vol.269
, pp. 8944-8951
-
-
Miquerol, L.1
Lopez, S.2
Cartier, N.3
Tulliez, M.4
Raymondjean, M.5
Kahn, A.6
-
12
-
-
0030695445
-
The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism
-
Stoffel M, Duncan SA. The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism. Proc Natl Acad Sci USA 1997; 94: 13209-13214.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13209-13214
-
-
Stoffel, M.1
Duncan, S.A.2
-
13
-
-
33749048777
-
In vitro differentiation of human placenta-derived multipotent cells into hepatocyte-like cells
-
Chien CC, Yen BL, Lee FK, Lai TH, Chen YC, Chan SH et al. In vitro differentiation of human placenta-derived multipotent cells into hepatocyte-like cells. Stem Cells 2006; 24: 1759-1768.
-
(2006)
Stem Cells
, vol.24
, pp. 1759-1768
-
-
Chien, C.C.1
Yen, B.L.2
Lee, F.K.3
Lai, T.H.4
Chen, Y.C.5
Chan, S.H.6
-
14
-
-
0037237461
-
Liver-specific gene expression in cultured human hematopoietic stem cells
-
Fiegel HC, Lioznov MV, Cortes-Dericks L, Lange C, Kluth D, Fehse B et al. Liver-specific gene expression in cultured human hematopoietic stem cells. Stem Cells 2003; 21: 98-104.
-
(2003)
Stem Cells
, vol.21
, pp. 98-104
-
-
Fiegel, H.C.1
Lioznov, M.V.2
Cortes-Dericks, L.3
Lange, C.4
Kluth, D.5
Fehse, B.6
-
15
-
-
33644931102
-
Failure of hepatocyte marker-expressing hematopoietic progenitor cells to efficiently convert into hepatocytes in vitro
-
Lian G, Wang C, Teng C, Zhang C, Du L, Zhong Q et al. Failure of hepatocyte marker-expressing hematopoietic progenitor cells to efficiently convert into hepatocytes in vitro. Exp Hematol 2006; 34: 348-358.
-
(2006)
Exp Hematol
, vol.34
, pp. 348-358
-
-
Lian, G.1
Wang, C.2
Teng, C.3
Zhang, C.4
Du, L.5
Zhong, Q.6
-
16
-
-
0038757830
-
Hepato-cyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis
-
Parviz F, Matullo C, Garrison WD, Savatski L, Adamson JW, Ning G et al. Hepato-cyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis. Nat Genet 2003; 34: 292-296.
-
(2003)
Nat Genet
, vol.34
, pp. 292-296
-
-
Parviz, F.1
Matullo, C.2
Garrison, W.D.3
Savatski, L.4
Adamson, J.W.5
Ning, G.6
-
17
-
-
0027662208
-
Orphan receptor HNF-4 and liver-specific gene expression
-
Sladek FM. Orphan receptor HNF-4 and liver-specific gene expression. Receptor 1993; 3: 223-232.
-
(1993)
Receptor
, vol.3
, pp. 223-232
-
-
Sladek, F.M.1
-
18
-
-
0035807902
-
A transcription factor regulatory circuit in differentiated pancreatic cells
-
Boj SF, Parrizas M, Maestro MA, Ferrer J. A transcription factor regulatory circuit in differentiated pancreatic cells. Proc Natl Acad Sci USA 2001; 98: 14481-14486.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 14481-14486
-
-
Boj, S.F.1
Parrizas, M.2
Maestro, M.A.3
Ferrer, J.4
-
19
-
-
0034777911
-
A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young
-
Thomas H, Jaschkowitz K, Bulman M, Frayling TM, Mitchell SM, Roosen S et al. A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young. Hum Mol Genet 2001; 10: 2089-2097.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 2089-2097
-
-
Thomas, H.1
Jaschkowitz, K.2
Bulman, M.3
Frayling, T.M.4
Mitchell, S.M.5
Roosen, S.6
-
20
-
-
33645283867
-
In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping
-
Briancon N, Weiss MC. In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping. EMBO J 2006; 25: 1253-1262.
-
(2006)
EMBO J
, vol.25
, pp. 1253-1262
-
-
Briancon, N.1
Weiss, M.C.2
-
21
-
-
0242349197
-
Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): Requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis
-
Rhee J, Inoue Y, Yoon JC, Puigserver P, Fan M, Gonzalez FJ et al. Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. Proc Natl Acad Sci USA 2003; 100: 4012-4017.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4012-4017
-
-
Rhee, J.1
Inoue, Y.2
Yoon, J.C.3
Puigserver, P.4
Fan, M.5
Gonzalez, F.J.6
-
22
-
-
0034680936
-
Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta-cell genes implicated in glucose metabolism and nutrient-induced insulin secretion
-
Wang H, Maechler P, Antinozzi PA, Hagenfeldt KA, Wollheim CB. Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta-cell genes implicated in glucose metabolism and nutrient-induced insulin secretion. J Biol Chem 2000; 275: 35953-35959.
-
(2000)
J Biol Chem
, vol.275
, pp. 35953-35959
-
-
Wang, H.1
Maechler, P.2
Antinozzi, P.A.3
Hagenfeldt, K.A.4
Wollheim, C.B.5
-
23
-
-
0037135622
-
Activation of the insulin gene promoter through a direct effect of hepatocyte nuclear factor 4 alpha
-
Bartoov-Shifman R, Hertz R, Wang H, Wollheim CB, Bar-Tana J, Walker MD. Activation of the insulin gene promoter through a direct effect of hepatocyte nuclear factor 4 alpha. J Biol Chem 2002; 277: 25914-25919.
-
(2002)
J Biol Chem
, vol.277
, pp. 25914-25919
-
-
Bartoov-Shifman, R.1
Hertz, R.2
Wang, H.3
Wollheim, C.B.4
Bar-Tana, J.5
Walker, M.D.6
-
24
-
-
34249290413
-
Molecular mechanism of basal CYP3A4 regulation by hepatocyte nuclear factor 4alpha: Evidence for direct regulation in the intestine
-
Tegude H, Schnabel A, Zanger UM, Klein K, Eichelbaum M, Burk O. Molecular mechanism of basal CYP3A4 regulation by hepatocyte nuclear factor 4alpha: evidence for direct regulation in the intestine. Drug Metab Dispos 2007; 35: 946-954.
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 946-954
-
-
Tegude, H.1
Schnabel, A.2
Zanger, U.M.3
Klein, K.4
Eichelbaum, M.5
Burk, O.6
-
25
-
-
0035960122
-
Molecular mechanisms and clinical pathophy-siology of maturity-onset diabetes of the young
-
Fajans SS, Bell GI, Polonsky KS. Molecular mechanisms and clinical pathophy-siology of maturity-onset diabetes of the young. N Engl J Med 2001; 345: 971-980.
-
(2001)
N Engl J Med
, vol.345
, pp. 971-980
-
-
Fajans, S.S.1
Bell, G.I.2
Polonsky, K.S.3
-
26
-
-
15944398611
-
Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes
-
Bagwell AM, Bento JL, Mychaleckyj JC, Freedman BI, Langefeld CD, Bowden DW. Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes. Diabetes 2005; 54: 1185-1190.
-
(2005)
Diabetes
, vol.54
, pp. 1185-1190
-
-
Bagwell, A.M.1
Bento, J.L.2
Mychaleckyj, J.C.3
Freedman, B.I.4
Langefeld, C.D.5
Bowden, D.W.6
-
27
-
-
16844386536
-
Variation near the hepatocyte nuclear factor (HNF)-4alpha gene associates with type 2 diabetes in the Danish population
-
Hansen SK, Rose CS, Glumer C, Drivsholm T, Borch-Johnsen K, Jorgensen T et al. Variation near the hepatocyte nuclear factor (HNF)-4alpha gene associates with type 2 diabetes in the Danish population. Diabetologia 2005; 48: 452-458.
-
(2005)
Diabetologia
, vol.48
, pp. 452-458
-
-
Hansen, S.K.1
Rose, C.S.2
Glumer, C.3
Drivsholm, T.4
Borch-Johnsen, K.5
Jorgensen, T.6
-
28
-
-
16844361887
-
Effect of common polymorphisms in the HNF4alpha promoter on susceptibility to type 2 diabetes in the French Caucasian population
-
Vaxillaire M, Dina C, Lobbens S, Dechaume A, Vasseur-Delannoy V, Helbecque N et al. Effect of common polymorphisms in the HNF4alpha promoter on susceptibility to type 2 diabetes in the French Caucasian population. Diabetologia 2005; 48: 440-444.
-
(2005)
Diabetologia
, vol.48
, pp. 440-444
-
-
Vaxillaire, M.1
Dina, C.2
Lobbens, S.3
Dechaume, A.4
Vasseur-Delannoy, V.5
Helbecque, N.6
-
29
-
-
33646477296
-
Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon
-
Garrison WD, Battle MA, Yang C, Kaestner KH, Sladek FM, Duncan SA. Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon. Gastroenterology 2006; 130: 1207-1220.
-
(2006)
Gastroenterology
, vol.130
, pp. 1207-1220
-
-
Garrison, W.D.1
Battle, M.A.2
Yang, C.3
Kaestner, K.H.4
Sladek, F.M.5
Duncan, S.A.6
-
30
-
-
84861871131
-
The transcription factor HNF-4alpha: A key factor of the intestinal uptake of fatty acids in mouse
-
Frochot V, Alqub M, Cattin AL, Carriere V, Houllier A, Baraille F et al. The transcription factor HNF-4alpha: a key factor of the intestinal uptake of fatty acids in mouse. Am J Physiol Gastrointest Liver Physiol 2012; 302: G1253-G1263.
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.302
-
-
Frochot, V.1
Alqub, M.2
Cattin, A.L.3
Carriere, V.4
Houllier, A.5
Baraille, F.6
-
31
-
-
39149087999
-
Hepatocyte nuclear factor-4alpha promotes differentiation of intestinal epithelial cells in a coculture system
-
Lussier CR, Babeu JP, Auclair BA, Perreault N, Boudreau F. Hepatocyte nuclear factor-4alpha promotes differentiation of intestinal epithelial cells in a coculture system. Am J Physiol Gastrointest Liver Physiol 2008; 294: G418-G428.
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.294
-
-
Lussier, C.R.1
Babeu, J.P.2
Auclair, B.A.3
Perreault, N.4
Boudreau, F.5
-
32
-
-
67650021574
-
Hepatocyte nuclear factor 4alpha contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation
-
Babeu JP, Darsigny M, Lussier CR, Boudreau F. Hepatocyte nuclear factor 4alpha contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation. Am J Physiol Gastrointest Liver Physiol 2009; 297: G124-G134.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.297
-
-
Babeu, J.P.1
Darsigny, M.2
Lussier, C.R.3
Boudreau, F.4
-
33
-
-
70449585192
-
Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice
-
Darsigny M, Babeu JP, Dupuis AA, Furth EE, Seidman EG, Levy E et al. Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice. PLoS One 2009; 4: e7609.
-
(2009)
PLoS One
, vol.4
-
-
Darsigny, M.1
Babeu, J.P.2
Dupuis, A.A.3
Furth, E.E.4
Seidman, E.G.5
Levy, E.6
-
34
-
-
78650343791
-
Modification in oxidative stress, inflammation and lipoprotein assembly in response to hepatocyte nuclear factor 4 alpha knockdown in intestinal epithelial cells
-
Marcil V, Seidman E, Sinnett D, Boudreau F, Gendron FP, Beaulieu JF et al. Modification in oxidative stress, inflammation and lipoprotein assembly in response to hepatocyte nuclear factor 4 alpha knockdown in intestinal epithelial cells. J Biol Chem 2010; 285: 40448-40460.
-
(2010)
J Biol Chem
, vol.285
, pp. 40448-40460
-
-
Marcil, V.1
Seidman, E.2
Sinnett, D.3
Boudreau, F.4
Gendron, F.P.5
Beaulieu, J.F.6
-
35
-
-
70649103789
-
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
-
Barrett JC, Lee JC, Lees CW, Prescott NJ, Anderson CA, Phillips A et al. Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet 2009; 41: 1330-1334.
-
(2009)
Nat Genet
, vol.41
, pp. 1330-1334
-
-
Barrett, J.C.1
Lee, J.C.2
Lees, C.W.3
Prescott, N.J.4
Anderson, C.A.5
Phillips, A.6
-
36
-
-
33750596924
-
Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns
-
Bonnycastle LL, Willer CJ, Conneely KN, Jackson AU, Burrill CP, Watanabe RM et al. Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns. Diabetes 2006; 55: 2534-2540.
-
(2006)
Diabetes
, vol.55
, pp. 2534-2540
-
-
Bonnycastle, L.L.1
Willer, C.J.2
Conneely, K.N.3
Jackson, A.U.4
Burrill, C.P.5
Watanabe, R.M.6
-
37
-
-
33747039577
-
Common hepatic nuclear factor-4alpha variants are associated with high serum lipid levels and the metabolic syndrome
-
Weissglas-Volkov D, Huertas-Vazquez A, Suviolahti E, Lee J, Plaisier C, Canizales-Quinteros S et al. Common hepatic nuclear factor-4alpha variants are associated with high serum lipid levels and the metabolic syndrome. Diabetes 2006; 55: 1970-1977.
-
(2006)
Diabetes
, vol.55
, pp. 1970-1977
-
-
Weissglas-Volkov, D.1
Huertas-Vazquez, A.2
Suviolahti, E.3
Lee, J.4
Plaisier, C.5
Canizales-Quinteros, S.6
-
38
-
-
84894353884
-
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
-
Silverberg MS, Satsangi J, Ahmad T, Arnott ID, Bernstein CN, Brant SR et al. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol 200519(Suppl A): 5-36.
-
(2005)
Can J Gastroenterol
, vol.19
, Issue.SUPPL. A
, pp. 5-36
-
-
Silverberg, M.S.1
Satsangi, J.2
Ahmad, T.3
Arnott, I.D.4
Bernstein, C.N.5
Brant, S.R.6
-
39
-
-
47949083278
-
Hepatocyte nuclear factor 4alpha in the intestinal epithelial cells protects against inflammatory bowel disease
-
Ahn SH, Shah YM, Inoue J, Morimura K, Kim I, Yim S et al. Hepatocyte nuclear factor 4alpha in the intestinal epithelial cells protects against inflammatory bowel disease. Inflamm Bowel Dis 2008; 14: 908-920.
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 908-920
-
-
Ahn, S.H.1
Shah, Y.M.2
Inoue, J.3
Morimura, K.4
Kim, I.5
Yim, S.6
-
40
-
-
33750475959
-
Cross-talk between nuclear receptors and nuclear factor kappaB
-
De BK, Vanden Berghe W, Haegeman G. Cross-talk between nuclear receptors and nuclear factor kappaB. Oncogene 2006; 25: 6868-6886.
-
(2006)
Oncogene
, vol.25
, pp. 6868-6886
-
-
De, B.K.1
Vanden Berghe, W.2
Haegeman, G.3
-
41
-
-
33748742725
-
Inhibition of hepatocyte nuclear factor 4 transcriptional activity by the nuclear factor kappaB pathway
-
Nikolaidou-Neokosmidou V, Zannis VI, Kardassis D. Inhibition of hepatocyte nuclear factor 4 transcriptional activity by the nuclear factor kappaB pathway. Biochem J 2006; 398: 439-450.
-
(2006)
Biochem J
, vol.398
, pp. 439-450
-
-
Nikolaidou-Neokosmidou, V.1
Zannis, V.I.2
Kardassis, D.3
-
42
-
-
77955285576
-
Association between genome-wide association studies reported SNPs and pediatric-onset Crohn's disease in Canadian children
-
Amre DK, Mack DR, Morgan K, Israel D, Deslandres C, Seidman EG et al. Association between genome-wide association studies reported SNPs and pediatric-onset Crohn's disease in Canadian children. Hum Genet 2010; 128: 131-135.
-
(2010)
Hum Genet
, vol.128
, pp. 131-135
-
-
Amre, D.K.1
MacK, D.R.2
Morgan, K.3
Israel, D.4
Deslandres, C.5
Seidman, E.G.6
-
43
-
-
84858150678
-
A common genetic background could explain early-onset Crohn's disease
-
Bianco AM, Zanin V, Girardelli M, Magnolato A, Martellossi S, Tommasini A et al. A common genetic background could explain early-onset Crohn's disease. Med Hypotheses 2012; 78: 520-522.
-
(2012)
Med Hypotheses
, vol.78
, pp. 520-522
-
-
Bianco, A.M.1
Zanin, V.2
Girardelli, M.3
Magnolato, A.4
Martellossi, S.5
Tommasini, A.6
-
44
-
-
0002772438
-
Hepatocyte nuclear factor 4á
-
Burris TP, McCabe E (eds) Academic Press: London, UK
-
Sladek FM, Seidel SD. Hepatocyte nuclear factor 4á. In: Burris TP, McCabe E (eds). Nuclear Receptors and Genetic Diseases. Academic Press: London, UK, 2001, pp 309-361.
-
(2001)
Nuclear Receptors and Genetic Diseases
, pp. 309-361
-
-
Sladek, F.M.1
Seidel, S.D.2
-
45
-
-
33748357551
-
Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha (HNF1A) and 4 alpha (HNF4A) in maturity-onset diabetes of the young
-
Ellard S, Colclough K. Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha (HNF1A) and 4 alpha (HNF4A) in maturity-onset diabetes of the young. Hum Mutat 2006; 27: 854-869.
-
(2006)
Hum Mutat
, vol.27
, pp. 854-869
-
-
Ellard, S.1
Colclough, K.2
-
46
-
-
57649190746
-
Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: A lesson for replication studies
-
Barroso I, Luan J, Wheeler E, Whittaker P, Wasson J, Zeggini E et al. Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies. Diabetes 2008; 57: 3161-3165.
-
(2008)
Diabetes
, vol.57
, pp. 3161-3165
-
-
Barroso, I.1
Luan, J.2
Wheeler, E.3
Whittaker, P.4
Wasson, J.5
Zeggini, E.6
-
47
-
-
33847029892
-
P2 promoter variants of the hepatocyte nuclear factor 4alpha gene are associated with type 2 diabetes in Mexican Americans
-
Lehman DM, Richardson DK, Jenkinson CP, Hunt KJ, Dyer TD, Leach RJ et al. P2 promoter variants of the hepatocyte nuclear factor 4alpha gene are associated with type 2 diabetes in Mexican Americans. Diabetes 2007; 56: 513-517.
-
(2007)
Diabetes
, vol.56
, pp. 513-517
-
-
Lehman, D.M.1
Richardson, D.K.2
Jenkinson, C.P.3
Hunt, K.J.4
Dyer, T.D.5
Leach, R.J.6
-
48
-
-
36849037397
-
Studies in 3523 Norwegians and meta-analysis in 11,571 subjects indicate that variants in the hepatocyte nuclear factor 4 alpha (HNF4A) P2 region are associated with type 2 diabetes in Scandinavians
-
Johansson S, Raeder H, Eide SA, Midthjell K, Hveem K, Sovik O et al. Studies in 3523 Norwegians and meta-analysis in 11,571 subjects indicate that variants in the hepatocyte nuclear factor 4 alpha (HNF4A) P2 region are associated with type 2 diabetes in Scandinavians. Diabetes 2007; 56: 3112-3117.
-
(2007)
Diabetes
, vol.56
, pp. 3112-3117
-
-
Johansson, S.1
Raeder, H.2
Eide, S.A.3
Midthjell, K.4
Hveem, K.5
Sovik, O.6
-
49
-
-
79960134827
-
Hepatocyte nuclear factor 4 alpha P2 promoter variants associate with insulin resistance
-
Saif-Ali R, Harun R, Al-Jassabi S, Wan Ngah WZ. Hepatocyte nuclear factor 4 alpha P2 promoter variants associate with insulin resistance. Acta Biochim Pol 2011; 58: 179-186.
-
(2011)
Acta Biochim Pol
, vol.58
, pp. 179-186
-
-
Saif-Ali, R.1
Harun, R.2
Al-Jassabi, S.3
Wan Ngah, W.Z.4
-
50
-
-
20044365215
-
Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7883 people
-
Winckler W, Graham RR, de Bakker PI, Sun M, Almgren P, Tuomi T et al. Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7883 people. Diabetes 2005; 54: 886-892.
-
(2005)
Diabetes
, vol.54
, pp. 886-892
-
-
Winckler, W.1
Graham, R.R.2
De Bakker, P.I.3
Sun, M.4
Almgren, P.5
Tuomi, T.6
-
51
-
-
59249097905
-
Shared susceptibility variations in autoimmune diseases: A brief perspective on common issues
-
Seldin MF, Amos CI. Shared susceptibility variations in autoimmune diseases: a brief perspective on common issues. Genes Immun 2009; 10: 1-4.
-
(2009)
Genes Immun
, vol.10
, pp. 1-4
-
-
Seldin, M.F.1
Amos, C.I.2
-
52
-
-
60849128209
-
Identifying disease associations via genome-wide association studies
-
Huang W, Wang P, Liu Z, Zhang L. Identifying disease associations via genome-wide association studies. BMC Bioinformatics 2009; 10(Suppl 1): S68.
-
(2009)
BMC Bioinformatics
, vol.10
, Issue.SUPPL. 1
-
-
Huang, W.1
Wang, P.2
Liu, Z.3
Zhang, L.4
-
53
-
-
77951210494
-
Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases
-
Eleftherohorinou H, Wright V, Hoggart C, Hartikainen AL, Jarvelin MR, Balding D et al. Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases. PLoS One 2009; 4: e8068.
-
(2009)
PLoS One
, vol.4
-
-
Eleftherohorinou, H.1
Wright, V.2
Hoggart, C.3
Hartikainen, A.L.4
Jarvelin, M.R.5
Balding, D.6
-
54
-
-
70249118941
-
DNA damage signalling recruits RREB-1 to the p53 tumour suppressor promoter
-
Liu H, Hew HC, Lu ZG, Yamaguchi T, Miki Y, Yoshida K. DNA damage signalling recruits RREB-1 to the p53 tumour suppressor promoter. Biochem J 2009; 422: 543-551.
-
(2009)
Biochem J
, vol.422
, pp. 543-551
-
-
Liu, H.1
Hew, H.C.2
Lu, Z.G.3
Yamaguchi, T.4
Miki, Y.5
Yoshida, K.6
-
56
-
-
33744795211
-
Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver
-
Battle MA, Konopka G, Parviz F, Gaggl AL, Yang C, Sladek FM et al. Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver. Proc Natl Acad Sci USA 2006; 103: 8419-8424.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 8419-8424
-
-
Battle, M.A.1
Konopka, G.2
Parviz, F.3
Gaggl, A.L.4
Yang, C.5
Sladek, F.M.6
-
57
-
-
25844464135
-
Behavior of tight-junction, adherens-junction and cell polarity proteins during HNF-4alpha-induced epithelial polarization
-
Satohisa S, Chiba H, Osanai M, Ohno S, Kojima T, Saito T et al. Behavior of tight-junction, adherens-junction and cell polarity proteins during HNF-4alpha-induced epithelial polarization. Exp Cell Res 2005; 310: 66-78.
-
(2005)
Exp Cell Res
, vol.310
, pp. 66-78
-
-
Satohisa, S.1
Chiba, H.2
Osanai, M.3
Ohno, S.4
Kojima, T.5
Saito, T.6
-
58
-
-
71949092030
-
Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium
-
Cattin AL, Le BJ, Barreau F, Saint-Just S, Houllier A, Gonzalez FJ et al. Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium. Mol Cell Biol 2009; 29: 6294-6308.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 6294-6308
-
-
Cattin, A.L.1
Le, B.J.2
Barreau, F.3
Saint-Just, S.4
Houllier, A.5
Gonzalez, F.J.6
-
59
-
-
0032831796
-
Status of lipidsoluble antioxidants and TRAP in patients with Crohn's disease and healthy controls
-
Genser D, Kang MH, Vogelsang H, Elmadfa I. Status of lipidsoluble antioxidants and TRAP in patients with Crohn's disease and healthy controls. Eur J Clin Nutr 1999; 53: 675-679.
-
(1999)
Eur J Clin Nutr
, vol.53
, pp. 675-679
-
-
Genser, D.1
Kang, M.H.2
Vogelsang, H.3
Elmadfa, I.4
-
60
-
-
0024810567
-
Classification of inflammatory bowel disease
-
Lennard-Jones JE. Classification of inflammatory bowel disease. Scand J Gastro-enterol Suppl 1989; 170: 2-6.
-
(1989)
Scand J Gastro-enterol Suppl
, vol.170
, pp. 2-6
-
-
Lennard-Jones, J.E.1
-
61
-
-
2442613767
-
From symptom to diagnosis: Clinical distinctions among various forms of intestinal inflammation
-
Sands BE. From symptom to diagnosis: clinical distinctions among various forms of intestinal inflammation. Gastroenterology 2004; 126: 1518-1532.
-
(2004)
Gastroenterology
, vol.126
, pp. 1518-1532
-
-
Sands, B.E.1
-
62
-
-
19944432946
-
Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies
-
Tang H, Quertermous T, Rodriguez B, Kardia SL, Zhu X, Brown A et al. Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet 2005; 76: 268-275.
-
(2005)
Am J Hum Genet
, vol.76
, pp. 268-275
-
-
Tang, H.1
Quertermous, T.2
Rodriguez, B.3
Kardia, S.L.4
Zhu, X.5
Brown, A.6
-
63
-
-
0038013035
-
The Quebec Child and Adolescent Health and Social Survey: Design and methods of a cardiovascular risk factor survey for youth
-
Paradis G, Lambert M, O'Loughlin J, Lavallee C, Aubin J, Berthiaume P et al. The Quebec Child and Adolescent Health and Social Survey: design and methods of a cardiovascular risk factor survey for youth. Can J Cardiol 2003; 19: 523-531.
-
(2003)
Can J Cardiol
, vol.19
, pp. 523-531
-
-
Paradis, G.1
Lambert, M.2
O'Loughlin, J.3
Lavallee, C.4
Aubin, J.5
Berthiaume, P.6
-
64
-
-
33746675027
-
Single nucleotide polymorphisms of the HNF4alpha gene are associated with the conversion to type 2 diabetes mellitus: The STOP-NIDDM trial
-
Andrulionyte L, Laukkanen O, Chiasson JL, Laakso M. Single nucleotide polymorphisms of the HNF4alpha gene are associated with the conversion to type 2 diabetes mellitus: the STOP-NIDDM trial. J Mol Med 2006; 84: 701-708.
-
(2006)
J Mol Med
, vol.84
, pp. 701-708
-
-
Andrulionyte, L.1
Laukkanen, O.2
Chiasson, J.L.3
Laakso, M.4
-
65
-
-
25844509429
-
Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians
-
Muller YL, Infante AM, Hanson RL, Love-Gregory L, Knowler W, Bogardus C et al. Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians. Diabetes 2005; 54: 3035-3039.
-
(2005)
Diabetes
, vol.54
, pp. 3035-3039
-
-
Muller, Y.L.1
Infante, A.M.2
Hanson, R.L.3
Love-Gregory, L.4
Knowler, W.5
Bogardus, C.6
-
66
-
-
0024297354
-
Multiple sequence alignment with hierarchical clustering
-
Corpet F. Multiple sequence alignment with hierarchical clustering. Nucleic Acids Res 1988; 16: 10881-10890.
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 10881-10890
-
-
Corpet, F.1
-
67
-
-
37249070232
-
Multiplexed genotyping of ABC transporter polymorphisms with the Bioplex suspension array
-
Koo SH, Ong TC, Chong KT, Lee CG, Chew FT, Lee EJ. Multiplexed genotyping of ABC transporter polymorphisms with the Bioplex suspension array. Biol Proced Online 2007; 9: 27-42.
-
(2007)
Biol Proced Online
, vol.9
, pp. 27-42
-
-
Koo, S.H.1
Ong, T.C.2
Chong, K.T.3
Lee, C.G.4
Chew, F.T.5
Lee, E.J.6
-
69
-
-
0033862733
-
Iron-ascorbate alters the efficiency of Caco-2 cells to assemble and secrete lipoproteins
-
Courtois F, Suc I, Garofalo C, Ledoux M, Seidman E, Levy E. Iron-ascorbate alters the efficiency of Caco-2 cells to assemble and secrete lipoproteins. Am J Physiol Gastrointest Liver Physiol 2000; 279: G12-G19.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.279
-
-
Courtois, F.1
Suc, I.2
Garofalo, C.3
Ledoux, M.4
Seidman, E.5
Levy, E.6
-
70
-
-
0033999250
-
Altered lipid profile, lipoprotein composition, and oxidant and antioxidant status in pediatric Crohn disease
-
Levy E, Rizwan Y, Thibault L, Lepage G, Brunet S, Bouthillier L et al. Altered lipid profile, lipoprotein composition, and oxidant and antioxidant status in pediatric Crohn disease. Am J Clin Nutr 2000; 71: 807-815.
-
(2000)
Am J Clin Nutr
, vol.71
, pp. 807-815
-
-
Levy, E.1
Rizwan, Y.2
Thibault, L.3
Lepage, G.4
Brunet, S.5
Bouthillier, L.6
-
71
-
-
13444269543
-
Haploview: Analysis and visualization of LD and haplotype maps
-
Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-265.
-
(2005)
Bioinformatics
, vol.21
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
|