-
1
-
-
0025040233
-
Suppression of human colorectal carcinoma cell growth by wild-type p53
-
Baker, S. J., Markowitz, S., Fearon, E. R., Willson, J. K. and Vogelstein, B. (1990) Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 249, 912-915
-
(1990)
Science
, vol.249
, pp. 912-915
-
-
Baker, S.J.1
Markowitz, S.2
Fearon, E.R.3
Willson, J.K.4
Vogelstein, B.5
-
2
-
-
0024382760
-
The p53 proto-oncogene can act as a suppressor of transformation
-
Finlay, C. A., Hinds, P. W. and Levine, A. J. (1989) The p53 proto-oncogene can act as a suppressor of transformation. Cell 57, 1083-1093
-
(1989)
Cell
, vol.57
, pp. 1083-1093
-
-
Finlay, C.A.1
Hinds, P.W.2
Levine, A.J.3
-
3
-
-
0842346437
-
Principles of tumour suppression
-
Sherr, C. J. (2004) Principles of tumour suppression. Cell 116, 235-246
-
(2004)
Cell
, vol.116
, pp. 235-246
-
-
Sherr, C.J.1
-
4
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein, B. and Kinzler, K. W. (2004) Cancer genes and the pathways they control. Nat. Med. 10, 789-799
-
(2004)
Nat. Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
5
-
-
0034676455
-
Surfing the p53 network
-
Vogelstein, B., Lane, D. and Levine, A. J. (2000) Surfing the p53 network. Nature 408, 307-310
-
(2000)
Nature
, vol.408
, pp. 307-310
-
-
Vogelstein, B.1
Lane, D.2
Levine, A.J.3
-
6
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden, K. H. and Lu, X. (2002) Live or let die: the cell's response to p53. Nat. Rev. Cancer 2, 594-604
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
7
-
-
46049090743
-
Nuclear trafficking of pro-apoptotic kinases in response to DNA damage
-
Yoshida, K. (2008) Nuclear trafficking of pro-apoptotic kinases in response to DNA damage. Trends Mol. Med. 14, 305-313
-
(2008)
Trends Mol. Med
, vol.14
, pp. 305-313
-
-
Yoshida, K.1
-
8
-
-
33847350861
-
DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage
-
Taira, N., Nihira, K., Yamaguchi, T., Miki, Y. and Yoshida, K. (2007) DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage. Mol. Cell 25, 725-738
-
(2007)
Mol. Cell
, vol.25
, pp. 725-738
-
-
Taira, N.1
Nihira, K.2
Yamaguchi, T.3
Miki, Y.4
Yoshida, K.5
-
9
-
-
31544457877
-
p53 ubiquitination: Mdm2 and beyond
-
Brooks, C. L. and Gu, W. (2006) p53 ubiquitination: Mdm2 and beyond. Mol. Cell 21, 307-315
-
(2006)
Mol. Cell
, vol.21
, pp. 307-315
-
-
Brooks, C.L.1
Gu, W.2
-
10
-
-
0030965946
-
Regulation of p53 stability by Mdm2
-
Kubbutat, M. H., Jones, S. N. and Vousden, K. H. (1997) Regulation of p53 stability by Mdm2. Nature 387, 299-303
-
(1997)
Nature
, vol.387
, pp. 299-303
-
-
Kubbutat, M.H.1
Jones, S.N.2
Vousden, K.H.3
-
11
-
-
0032475878
-
Signaling to p53: Breaking the MDM2-p53 circuit
-
Prives, C. (1998) Signaling to p53: breaking the MDM2-p53 circuit. Cell 95, 5-8
-
(1998)
Cell
, vol.95
, pp. 5-8
-
-
Prives, C.1
-
12
-
-
0001837570
-
Functions of the MDM2 oncoprotein
-
Freedman, D. A., Wu, L. and Levine, A. J. (1999) Functions of the MDM2 oncoprotein. Cell. Mol. Life Sci. 55, 96-107
-
(1999)
Cell. Mol. Life Sci
, vol.55
, pp. 96-107
-
-
Freedman, D.A.1
Wu, L.2
Levine, A.J.3
-
13
-
-
4944255743
-
Post-translational modification of p53 in tumourigenesis
-
Bode, A. M. and Dong, Z. (2004) Post-translational modification of p53 in tumourigenesis. Nat. Rev. Cancer 4, 793-805
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 793-805
-
-
Bode, A.M.1
Dong, Z.2
-
14
-
-
26244459242
-
Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin
-
Takagi, M., Absalon, M. J., McLure, K. G. and Kastan, M. B. (2005) Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin. Cell 123, 49-63
-
(2005)
Cell
, vol.123
, pp. 49-63
-
-
Takagi, M.1
Absalon, M.J.2
McLure, K.G.3
Kastan, M.B.4
-
15
-
-
0034702232
-
Compromised HOXA5 function can limit p53 expression in human breast tumours
-
Raman, V., Martensen, S. A., Reisman, D., Evron, E., Odenwald, W. F., Jaffee, E., Marks, J. and Sukumar, S. (2000) Compromised HOXA5 function can limit p53 expression in human breast tumours. Nature 405, 974-978
-
(2000)
Nature
, vol.405
, pp. 974-978
-
-
Raman, V.1
Martensen, S.A.2
Reisman, D.3
Evron, E.4
Odenwald, W.F.5
Jaffee, E.6
Marks, J.7
Sukumar, S.8
-
16
-
-
0041662272
-
Integration of interferon-α/β signalling to p53 responses in tumour suppression and antiviral defence
-
Takaoka, A., Hayakawa, S., Yanai, H., Stoiber, D., Negishi, H., Kikuchi, H., Sasaki, S., Imai, K., Shibue, T., Honda, K. and Taniguchi, T. (2003) Integration of interferon-α/β signalling to p53 responses in tumour suppression and antiviral defence. Nature 424, 516-523
-
(2003)
Nature
, vol.424
, pp. 516-523
-
-
Takaoka, A.1
Hayakawa, S.2
Yanai, H.3
Stoiber, D.4
Negishi, H.5
Kikuchi, H.6
Sasaki, S.7
Imai, K.8
Shibue, T.9
Honda, K.10
Taniguchi, T.11
-
17
-
-
35548949865
-
Transcriptional activation of p53 by Pitx1
-
Liu, D. X. and Lobie, P. E. (2007) Transcriptional activation of p53 by Pitx1. Cell Death Differ. 14, 1893-1907
-
(2007)
Cell Death Differ
, vol.14
, pp. 1893-1907
-
-
Liu, D.X.1
Lobie, P.E.2
-
18
-
-
37549051733
-
Protein kinase C delta induces transcription of the TP53 tumour suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage
-
Liu, H., Lu, Z. G., Miki, Y. and Yoshida, K. (2007) Protein kinase C delta induces transcription of the TP53 tumour suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage. Mol. Cell. Biol. 27, 8480-8491
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 8480-8491
-
-
Liu, H.1
Lu, Z.G.2
Miki, Y.3
Yoshida, K.4
-
19
-
-
33646229039
-
Protein Kinase Cδ regulates Ser46 phosphorylation of p53 tumour suppressor in the apoptotic response to DNA damage
-
Yoshida, K., Liu, H. and Miki, Y. (2006) Protein Kinase Cδ regulates Ser46 phosphorylation of p53 tumour suppressor in the apoptotic response to DNA damage. J. Biol. Chem. 281, 5734-5740
-
(2006)
J. Biol. Chem
, vol.281
, pp. 5734-5740
-
-
Yoshida, K.1
Liu, H.2
Miki, Y.3
-
20
-
-
10344247666
-
The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells
-
Phan, R. T. and Dalla-Favera, R. (2004) The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells. Nature 432, 635-639
-
(2004)
Nature
, vol.432
, pp. 635-639
-
-
Phan, R.T.1
Dalla-Favera, R.2
-
21
-
-
33746865877
-
p73 or p53 directly regulates human p53 transcription to maintain cell cycle checkpoints
-
Wang, S. and El-Deiry, W. S. (2006) p73 or p53 directly regulates human p53 transcription to maintain cell cycle checkpoints. Cancer Res. 66, 6982-6989
-
(2006)
Cancer Res
, vol.66
, pp. 6982-6989
-
-
Wang, S.1
El-Deiry, W.S.2
-
22
-
-
0036241988
-
c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage
-
Yoshida, K., Komatsu, K., Wang, H. G. and Kufe, D. (2002) c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage. Mol. Cell. Biol. 22, 3292-3300
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 3292-3300
-
-
Yoshida, K.1
Komatsu, K.2
Wang, H.G.3
Kufe, D.4
-
23
-
-
0038237433
-
Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9
-
Yoshida, K., Wang, H. G., Miki, Y. and Kufe, D. (2003) Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9. EMBO J. 22, 1431-1441
-
(2003)
EMBO J
, vol.22
, pp. 1431-1441
-
-
Yoshida, K.1
Wang, H.G.2
Miki, Y.3
Kufe, D.4
-
24
-
-
14744301343
-
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage
-
Yoshida, K., Yamaguchi, T., Natsume, T., Kufe, D. and Miki, Y. (2005) JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage. Nat. Cell Biol. 7, 278-285
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 278-285
-
-
Yoshida, K.1
Yamaguchi, T.2
Natsume, T.3
Kufe, D.4
Miki, Y.5
-
25
-
-
33646257584
-
Protein kinase Cδ activates topoisomerase IIα to induce apoptotic cell death in response to DNA damage
-
Yoshida, K., Yamaguchi, T., Shinagawa, H., Taira, N., Nakayama, K. I. and Miki, Y. (2006) Protein kinase Cδ activates topoisomerase IIα to induce apoptotic cell death in response to DNA damage. Mol. Cell. Biol. 26, 3414-3431
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 3414-3431
-
-
Yoshida, K.1
Yamaguchi, T.2
Shinagawa, H.3
Taira, N.4
Nakayama, K.I.5
Miki, Y.6
-
26
-
-
0035216604
-
Negative regulation of the SHPTP1 protein tyrosine phosphatase by protein kinase Cδ in response to DNA damage
-
Yoshida, K. and Kufe, D. (2001) Negative regulation of the SHPTP1 protein tyrosine phosphatase by protein kinase Cδ in response to DNA damage. Mol. Pharmacol. 60, 1431-1438
-
(2001)
Mol. Pharmacol
, vol.60
, pp. 1431-1438
-
-
Yoshida, K.1
Kufe, D.2
-
27
-
-
0033520997
-
Functional interaction between SHPTP1 and the Lyn tyrosine kinase in the apoptotic response to DNA damage
-
Yoshida, K., Kharbanda, S. and Kufe, D. (1999) Functional interaction between SHPTP1 and the Lyn tyrosine kinase in the apoptotic response to DNA damage. J. Biol. Chem. 274, 34663-34668
-
(1999)
J. Biol. Chem
, vol.274
, pp. 34663-34668
-
-
Yoshida, K.1
Kharbanda, S.2
Kufe, D.3
-
28
-
-
0033927555
-
Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage
-
Yoshida, K., Weichselbaum, R., Kharbanda, S. and Kufe, D. (2000) Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage. Mol. Cell. Biol. 20, 5370-5380
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 5370-5380
-
-
Yoshida, K.1
Weichselbaum, R.2
Kharbanda, S.3
Kufe, D.4
-
29
-
-
2242473920
-
Activation of SAPK/JNK signaling by protein kinase Cδ in response to DNA damage
-
Yoshida, K., Miki, Y. and Kufe, D. (2002) Activation of SAPK/JNK signaling by protein kinase Cδ in response to DNA damage. J. Biol. Chem. 277, 48372-48378
-
(2002)
J. Biol. Chem
, vol.277
, pp. 48372-48378
-
-
Yoshida, K.1
Miki, Y.2
Kufe, D.3
-
30
-
-
36348975260
-
The deubiquitinating enzyme USP11 controls an IKKα-p53 signaling pathway in response to TNFα
-
Yamaguchi, T., Kimura, J., Miki, Y. and Yoshida, K. (2007) The deubiquitinating enzyme USP11 controls an IKKα-p53 signaling pathway in response to TNFα. J. Biol. Chem. 282, 33943-33948
-
(2007)
J. Biol. Chem
, vol.282
, pp. 33943-33948
-
-
Yamaguchi, T.1
Kimura, J.2
Miki, Y.3
Yoshida, K.4
-
31
-
-
34548432969
-
Protein kinase C delta activates IκB-kinase α to induce the p53 tumour suppressor in response to oxidative stress
-
Yamaguchi, T., Miki, Y. and Yoshida, K. (2007) Protein kinase C delta activates IκB-kinase α to induce the p53 tumour suppressor in response to oxidative stress. Cell. Signalling 19, 2088-2097
-
(2007)
Cell. Signalling
, vol.19
, pp. 2088-2097
-
-
Yamaguchi, T.1
Miki, Y.2
Yoshida, K.3
-
32
-
-
0029007316
-
Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression
-
Sun, X., Shimizu, H. and Yamamoto, K. (1995) Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression. Mol. Cell. Biol. 15, 4489-4496
-
(1995)
Mol. Cell. Biol
, vol.15
, pp. 4489-4496
-
-
Sun, X.1
Shimizu, H.2
Yamamoto, K.3
-
33
-
-
31544477735
-
Increased p53 transcription prior to DNA synthesis is regulated through a novel regulatory element within the p53 promoter
-
Boggs, K. and Reisman, D. (2006) Increased p53 transcription prior to DNA synthesis is regulated through a novel regulatory element within the p53 promoter. Oncogene 25, 555-565
-
(2006)
Oncogene
, vol.25
, pp. 555-565
-
-
Boggs, K.1
Reisman, D.2
-
34
-
-
10144220638
-
RREB-1, a novel zinc finger protein, is involved in the differentiation response to Ras in human medullary thyroid carcinomas
-
Thiagalingam, A., De Bustros, A., Borges, M., Jasti, R., Compton, D., Diamond, L., Mabry, M., Ball, D. W., Baylin, S. B. and Nelkin, B. D. (1996) RREB-1, a novel zinc finger protein, is involved in the differentiation response to Ras in human medullary thyroid carcinomas. Mol. Cell. Biol. 16, 5335-5345
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 5335-5345
-
-
Thiagalingam, A.1
De Bustros, A.2
Borges, M.3
Jasti, R.4
Compton, D.5
Diamond, L.6
Mabry, M.7
Ball, D.W.8
Baylin, S.B.9
Nelkin, B.D.10
-
35
-
-
0033565650
-
A human Raf-responsive zinc-finger protein that binds to divergent sequences
-
Zhang, L., Zhao, J. and Edenberg, H. J. (1999) A human Raf-responsive zinc-finger protein that binds to divergent sequences. Nucleic Acids Res. 27, 2947-2956
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 2947-2956
-
-
Zhang, L.1
Zhao, J.2
Edenberg, H.J.3
-
36
-
-
0030807174
-
A novel zinc finger protein, Finb, is a transcriptional activator and localized in nuclear bodies
-
Fujimoto-Nishiyama, A., Ishii, S., Matsuda, S., Inoue, J. and Yamamoto, T. (1997) A novel zinc finger protein, Finb, is a transcriptional activator and localized in nuclear bodies. Gene 195, 267-275
-
(1997)
Gene
, vol.195
, pp. 267-275
-
-
Fujimoto-Nishiyama, A.1
Ishii, S.2
Matsuda, S.3
Inoue, J.4
Yamamoto, T.5
-
37
-
-
0037214281
-
Novel transcriptional potentiation of BETA2/NeuroD on the secretin gene promoter by the DNA-binding protein Finb/RREB-1
-
Ray, S. K., Nishitani, J., Petry, M. W., Fessing, M. Y. and Leiter, A. B. (2003) Novel transcriptional potentiation of BETA2/NeuroD on the secretin gene promoter by the DNA-binding protein Finb/RREB-1. Mol. Cell. Biol. 23, 259-271
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 259-271
-
-
Ray, S.K.1
Nishitani, J.2
Petry, M.W.3
Fessing, M.Y.4
Leiter, A.B.5
-
38
-
-
0038523839
-
p16 INK4a gene promoter variation and differential binding of a repressor, the ras-responsive zinc-finger transcription factor, RREB
-
Zhang, S., Qian, X., Redman, C., Bliskovski, V., Ramsay, E. S., Lowy, D. R. and Mock, B. A. (2003) p16 INK4a gene promoter variation and differential binding of a repressor, the ras-responsive zinc-finger transcription factor, RREB. Oncogene 22, 2285-2295
-
(2003)
Oncogene
, vol.22
, pp. 2285-2295
-
-
Zhang, S.1
Qian, X.2
Redman, C.3
Bliskovski, V.4
Ramsay, E.S.5
Lowy, D.R.6
Mock, B.A.7
-
39
-
-
16644376712
-
Finb, a multiple zinc finger protein, represses transcription of the human angiotensinogen gene
-
Date, S., Nibu, Y., Yanai, K., Hirata, J., Yagami, K. and Fukamizu, A. (2004) Finb, a multiple zinc finger protein, represses transcription of the human angiotensinogen gene. Int. J. Mol. Med. 13, 637-642
-
(2004)
Int. J. Mol. Med
, vol.13
, pp. 637-642
-
-
Date, S.1
Nibu, Y.2
Yanai, K.3
Hirata, J.4
Yagami, K.5
Fukamizu, A.6
-
40
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
Shi, Y., Lan, F., Matson, C., Mulligan, P., Whetstine, J. R., Cole, P. A., Casero, R. A. and Shi, Y. (2004) Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119, 941-953
-
(2004)
Cell
, vol.119
, pp. 941-953
-
-
Shi, Y.1
Lan, F.2
Matson, C.3
Mulligan, P.4
Whetstine, J.R.5
Cole, P.A.6
Casero, R.A.7
Shi, Y.8
-
41
-
-
0031987284
-
Transcriptional regulation of the p53 tumour suppressor gene
-
Reisman, D. and Loging, W. T. (1998) Transcriptional regulation of the p53 tumour suppressor gene. Semin. Cancer Biol. 8, 317-324
-
(1998)
Semin. Cancer Biol
, vol.8
, pp. 317-324
-
-
Reisman, D.1
Loging, W.T.2
-
42
-
-
0024573893
-
Characterization of the human p53 gene promoter
-
Tuck, S. P. and Crawford, L. (1989) Characterization of the human p53 gene promoter. Mol. Cell. Biol. 9, 2163-2172
-
(1989)
Mol. Cell. Biol
, vol.9
, pp. 2163-2172
-
-
Tuck, S.P.1
Crawford, L.2
|