In vivo role of the HNF4α AF-1 activation domain revealed by exon swapping

EMBO Journal

Volumn 25, Issue 6, 2006, Pages 1253-1262

  Briançon, Nadège ^a   Weiss, Mary C ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

Activation function; Isoform; Lipid metabolism; Nuclear receptor 2a1; Type II diabetes mellitus

Indexed keywords

CELL NUCLEUS RECEPTOR; NUCLEAR RECEPTOR HEPATOCYTE NUCLEAR FACTOR ALPHA; UNCLASSIFIED DRUG; CRE RECOMBINASE; HEPATOCYTE NUCLEAR FACTOR 4; HNF4A PROTEIN, MOUSE; INTEGRASE; ISOPROTEIN; LIPID; PRIMER DNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DYSLIPIDEMIA; EXON; FEMALE; GENE ACTIVATION; GENE DISRUPTION; GENE EXPRESSION; GENE IDENTIFICATION; GENE TARGETING; GENETIC CODE; GLUCOSE TOLERANCE; IN VIVO STUDY; KNOCKOUT MOUSE; LETHALITY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; ALTERNATIVE RNA SPLICING; ANIMAL; C57BL MOUSE; CHEMISTRY; CHROMATIN IMMUNOPRECIPITATION; COMPARATIVE STUDY; GENE EXPRESSION REGULATION; GENETICS; GLUCOSE TOLERANCE TEST; LETHAL GENE; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; TRANSACTIVATION;

ANIMALIA;

ALTERNATIVE SPLICING; ANIMALS; CHROMATIN IMMUNOPRECIPITATION; DNA PRIMERS; DYSLIPIDEMIAS; EXONS; FEMALE; GENE EXPRESSION REGULATION; GENES, LETHAL; GLUCOSE TOLERANCE TEST; HEPATOCYTE NUCLEAR FACTOR 4; INTEGRASES; LIPIDS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROMOTER REGIONS (GENETICS); PROTEIN ISOFORMS; TRANS-ACTIVATION (GENETICS);

EID: 33645283867     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601021     Document Type: Article

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