메뉴 건너뛰기




Volumn 303, Issue 8, 2012, Pages

Neuronal Wiskott-Aldrich syndrome protein (N-WASP) is critical for formation of α-smooth muscle action filaments during myofibroblast differentiation

Author keywords

Fibroblast; Fibrosis; Focal adhesion kinase; Lung fibrosis; Transforming growth factor

Indexed keywords

ACTIN RELATED PROTEIN 2-3 COMPLEX; ALPHA SMOOTH MUSCLE ACTIN; FOCAL ADHESION KINASE; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN; SHORT HAIRPIN RNA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84867722834     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00390.2011     Document Type: Article
Times cited : (28)

References (52)
  • 1
    • 0028086164 scopus 로고
    • Dependence of collagen remodeling on alpha-smooth muscle actin expression by fibroblasts
    • Arora PD, McCulloch CA. Dependence of collagen remodeling on alpha-smooth muscle actin expression by fibroblasts. J Cell Physiol 159: 161-175, 1994.
    • (1994) J Cell Physiol , vol.159 , pp. 161-175
    • Arora, P.D.1    McCulloch, C.A.2
  • 2
    • 0345550397 scopus 로고    scopus 로고
    • FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies
    • Beggs HE, Schahin-Reed D, Zang K, Goebbels S, Nave KA, Gorski J, Jones KR, Sretavan D, Reichardt LF. FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies. Neuron 40: 501-514, 2003.
    • (2003) Neuron , vol.40 , pp. 501-514
    • Beggs, H.E.1    Schahin-Reed, D.2    Zang, K.3    Goebbels, S.4    Nave, K.A.5    Gorski, J.6    Jones, K.R.7    Sretavan, D.8    Reichardt, L.F.9
  • 3
    • 4644342865 scopus 로고    scopus 로고
    • Regulation of WASP/WAVE proteins: Making a long story short
    • Bompard G, Caron E. Regulation of WASP/WAVE proteins: making a long story short. J Cell Biol 166: 957-962, 2004.
    • (2004) J Cell Biol , vol.166 , pp. 957-962
    • Bompard, G.1    Caron, E.2
  • 4
    • 77952763874 scopus 로고    scopus 로고
    • Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts
    • Cai GQ, Zheng A, Tang Q, White ES, Chou CF, Gladson CL, Olman MA, Ding Q. Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts. Exp Cell Res 316: 1600-1609, 2010.
    • (2010) Exp Cell Res , vol.316 , pp. 1600-1609
    • Cai, G.Q.1    Zheng, A.2    Tang, Q.3    White, E.S.4    Chou, C.F.5    Gladson, C.L.6    Olman, M.A.7    Ding, Q.8
  • 5
    • 77950550875 scopus 로고    scopus 로고
    • Force-induced myofibroblast differentiation through collagen receptors is dependent on mammalian diaphanous (mDia)
    • Chan MW, Chaudary F, Lee W, Copeland JW, McCulloch CA. Force-induced myofibroblast differentiation through collagen receptors is dependent on mammalian diaphanous (mDia). J Biol Chem 285: 9273-9281, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 9273-9281
    • Chan, M.W.1    Chaudary, F.2    Lee, W.3    Copeland, J.W.4    McCulloch, C.A.5
  • 6
    • 0028984528 scopus 로고
    • The specific NH2-terminal sequence Ac-EEED of alpha-smooth muscle actin plays a role in polymerization in vitro and in vivo
    • Chaponnier C, Goethals M, Janmey PA, Gabbiani F, Gabbiani G, Vandekerckhove J. The specific NH2-terminal sequence Ac-EEED of alpha-smooth muscle actin plays a role in polymerization in vitro and in vivo. J Cell Biol 130: 887-895, 1995.
    • (1995) J Cell Biol , vol.130 , pp. 887-895
    • Chaponnier, C.1    Goethals, M.2    Janmey, P.A.3    Gabbiani, F.4    Gabbiani, G.5    Vandekerckhove, J.6
  • 7
    • 0025306468 scopus 로고
    • Alpha-smooth muscle action is transiently expressed by myofibroblasts during experimental wound healing
    • Darby I, Skalli O, Gabbiani G. Alpha-smooth muscle action is transiently expressed by myofibroblasts during experimental wound healing. Lab Invest 63: 21-29, 1990.
    • (1990) Lab Invest , vol.63 , pp. 21-29
    • Darby, I.1    Skalli, O.2    Gabbiani, G.3
  • 9
    • 0027212686 scopus 로고
    • Transforming growth factor-beta 1 induces alpha-smooth muscle action expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
    • Desmouliere A, Geinoz A, Gabbiani F, Gabbiani G. Transforming growth factor-beta 1 induces alpha-smooth muscle action expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biochem 122: 103-111, 1993.
    • (1993) J Cell Biochem , vol.122 , pp. 103-111
    • Desmouliere, A.1    Geinoz, A.2    Gabbiani, F.3    Gabbiani, G.4
  • 10
    • 55249089456 scopus 로고    scopus 로고
    • FAK-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner
    • Ding Q, Gladson CL, Wu H, Hayasaka H, Olman MA. FAK-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner. J Biol Chem 283: 26839-26849, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 26839-26849
    • Ding, Q.1    Gladson, C.L.2    Wu, H.3    Hayasaka, H.4    Olman, M.A.5
  • 11
    • 14844327984 scopus 로고    scopus 로고
    • P27KIP1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain
    • Ding Q, Grammer JR, Nelson MA, Guan JL, Stewart JE Jr, Gladson CL. p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain. J Biol Chem 280: 6802-6815, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 6802-6815
    • Ding, Q.1    Grammer, J.R.2    Nelson, M.A.3    Guan, J.L.4    Stewart Jr., J.E.5    Gladson, C.L.6
  • 13
    • 0141994778 scopus 로고    scopus 로고
    • The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged
    • Ding Q, Stewart J Jr, Olman MA, Klobe MR, Gladson CL. The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged. J Biol Chem 278: 39882-39891, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 39882-39891
    • Ding, Q.1    Stewart Jr., J.2    Olman, M.A.3    Klobe, M.R.4    Gladson, C.L.5
  • 14
    • 0037105704 scopus 로고    scopus 로고
    • Promotion of malignant astrocytoma cell migration by osteopontin expressed in the normal brain:Differences in integrin signaling during cell adhesion to osteopontin vs.vitronectin
    • Ding Q, Stewart J Jr, Prince CW, Chang PL, Trikha M, Han X, Grammer JR, Gladson CL. Promotion of malignant astrocytoma cell migration by osteopontin expressed in the normal brain: differences in integrin signaling during cell adhesion to osteopontin vs. vitronectin. Cancer Res 62: 5336-5343, 2002.
    • (2002) Cancer Res , vol.62 , pp. 5336-5343
    • Ding, Q.1    Stewart Jr., J.2    Prince, C.W.3    Chang, P.L.4    Trikha, M.5    Han, X.6    Grammer, J.R.7    Gladson, C.L.8
  • 15
    • 70450245305 scopus 로고    scopus 로고
    • Actin filament nucleation and elongation factors-structure-function relationships
    • Dominguez R. Actin filament nucleation and elongation factors-structure-function relationships. Crit Rev Biochem Mol Biol 44: 351-366, 2009.
    • (2009) Crit Rev Biochem Mol Biol , vol.44 , pp. 351-366
    • Dominguez, R.1
  • 16
    • 0015225464 scopus 로고
    • Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction
    • Gabbiani G, Ryan GB, Majne G. Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction. Experien-tia 27: 549-550, 1971.
    • (1971) Experien-tia , vol.27 , pp. 549-550
    • Gabbiani, G.1    Ryan, G.B.2    Majne, G.3
  • 17
    • 0027955331 scopus 로고
    • Fibroblasts, Myofibroblasts, and wound contraction
    • Grinnell F. Fibroblasts, Myofibroblasts, and wound contraction. J Cell Biol 124: 401-404, 1994.
    • (1994) J Cell Biol , vol.124 , pp. 401-404
    • Grinnell, F.1
  • 18
    • 35848952094 scopus 로고    scopus 로고
    • Muscle fatigue: MK2 signaling and myofibro-blast differentiation
    • Hagood JS, Olman MA. Muscle fatigue: MK2 signaling and myofibro-blast differentiation. Am J Respir Cell Mol Biol 37: 503-506, 2007.
    • (2007) Am J Respir Cell Mol Biol , vol.37 , pp. 503-506
    • Hagood, J.S.1    Olman, M.A.2
  • 19
    • 0033843257 scopus 로고    scopus 로고
    • Focal adhesion kinase functions as a receptor-proximal signaling component required for directed cell migration
    • Hauck CR, Klingbeil CK, Schlaepfer DD. Focal adhesion kinase functions as a receptor-proximal signaling component required for directed cell migration. Immunol Res 21: 293-303, 2000.
    • (2000) Immunol Res , vol.21 , pp. 293-303
    • Hauck, C.R.1    Klingbeil, C.K.2    Schlaepfer, D.D.3
  • 20
    • 0035159094 scopus 로고    scopus 로고
    • Alpha-smooth muscle actin expression upregulates fibroblast contractile activity
    • Hinz B, Celetta G, Tomasek JJ, Gabbiani G, Chaponnier C. Alpha-smooth muscle actin expression upregulates fibroblast contractile activity. Mol Biol Cell 12: 2730-2741, 2001.
    • (2001) Mol Biol Cell , vol.12 , pp. 2730-2741
    • Hinz, B.1    Celetta, G.2    Tomasek, J.J.3    Gabbiani, G.4    Chaponnier, C.5
  • 21
    • 0037632844 scopus 로고    scopus 로고
    • Alpha-smooth muscle action is crucial for focal adhesion maturation in myofibroblasts
    • Hinz B, Dugina V, Ballestrem C, Wehrle-Haller B, Chaponnier C. Alpha-smooth muscle action is crucial for focal adhesion maturation in myofibroblasts. Mol Biol Cell 14: 2508-2519, 2003.
    • (2003) Mol Biol Cell , vol.14 , pp. 2508-2519
    • Hinz, B.1    Dugina, V.2    Ballestrem, C.3    Wehrle-Haller, B.4    Chaponnier, C.5
  • 22
    • 0037070964 scopus 로고    scopus 로고
    • The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo
    • Hinz B, Gabbiani G, Chaponnier C. The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo. J Cell Biochem 157: 657-663, 2002.
    • (2002) J Cell Biochem , vol.157 , pp. 657-663
    • Hinz, B.1    Gabbiani, G.2    Chaponnier, C.3
  • 24
    • 33847171545 scopus 로고    scopus 로고
    • Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofi-broblasts
    • Horowitz JC, Rogers DS, Sharma V, Vittal R, White ES, Cui Z, Thannickal VJ. Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofi-broblasts. Cell Signal 19: 761-771, 2007.
    • (2007) Cell Signal , vol.19 , pp. 761-771
    • Horowitz, J.C.1    Rogers, D.S.2    Sharma, V.3    Vittal, R.4    White, E.S.5    Cui, Z.6    Thannickal, V.J.7
  • 27
    • 0242319836 scopus 로고    scopus 로고
    • 2 inhibits fibroblast to myofibroblast transition via E prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation
    • Kolodsick JE, Peters-Golden M, Larios JM, Toews GB, Thannickal VJ, Moore BB. Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation. Am J Respir Cell Mol Biol 29: 537-544, 2003.
    • (2003) Am J Respir Cell Mol Biol , vol.29 , pp. 537-544
    • Kolodsick, J.E.1    Peters-Golden, M.2    Larios, J.M.3    Toews, G.B.4    Thannickal, V.J.5    Moore, B.B.6
  • 29
    • 73949143585 scopus 로고    scopus 로고
    • Small cytoskeleton-associated molecule, fibroblast growth factor receptor 1 oncogene partner 2/wound inducible transcript-3.0 (FGFR1OP2/wit30), facilitates fibroblast-driven wound closure
    • Lin A, Hokugo A, Choi J, Nishimura I. Small cytoskeleton-associated molecule, fibroblast growth factor receptor 1 oncogene partner 2/wound inducible transcript-3.0 (FGFR1OP2/wit30), facilitates fibroblast-driven wound closure. Am J Pathol 176: 108-121, 2010.
    • (2010) Am J Pathol , vol.176 , pp. 108-121
    • Lin, A.1    Hokugo, A.2    Choi, J.3    Nishimura, I.4
  • 31
    • 33645960124 scopus 로고    scopus 로고
    • Therapeutic strategies against TGF-beta signaling pathway in hepatic fibrosis
    • Liu X, Hu H, Yin JQ. Therapeutic strategies against TGF-beta signaling pathway in hepatic fibrosis. Liver Int 26: 8-22, 2006.
    • (2006) Liver Int , vol.26 , pp. 8-22
    • Liu, X.1    Hu, H.2    Yin, J.Q.3
  • 34
    • 0037509990 scopus 로고    scopus 로고
    • Focal adhesion kinase: The first ten years
    • Parsons JT. Focal adhesion kinase: the first ten years. J Cell Sci 116: 1409-1416, 2003.
    • (2003) J Cell Sci , vol.116 , pp. 1409-1416
    • Parsons, J.T.1
  • 35
    • 0036933489 scopus 로고    scopus 로고
    • The myofibroblast in pulmonary fibrosis
    • Phan SH. The myofibroblast in pulmonary fibrosis. Chest 122: 286S-289S, 2002.
    • (2002) Chest , vol.122
    • Phan, S.H.1
  • 36
    • 0037459075 scopus 로고    scopus 로고
    • Cellular motility driven by assembly and disassembly of actin filaments
    • Pollard TD, Borisy GG. Cellular motility driven by assembly and disassembly of actin filaments. Cell 112: 453-465, 2003.
    • (2003) Cell , vol.112 , pp. 453-465
    • Pollard, T.D.1    Borisy, G.G.2
  • 37
    • 0033574722 scopus 로고    scopus 로고
    • The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly
    • Rohatgi R, Ma L, Miki H, Lopez M, Kirchhausen T, Takenawa T, Kirschner MW. The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell 97: 221-231, 1999.
    • (1999) Cell , vol.97 , pp. 221-231
    • Rohatgi, R.1    Ma, L.2    Miki, H.3    Lopez, M.4    Kirchhausen, T.5    Takenawa, T.6    Kirschner, M.W.7
  • 38
    • 0030051051 scopus 로고    scopus 로고
    • Cellular changes involved in conversion of normal to malignant breast: Importance of the stromal reaction
    • Ronnov-Jessen L, Petersen OW, Bissell MJ. Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction. Physiol Rev 76: 69-125, 1996.
    • (1996) Physiol Rev , vol.76 , pp. 69-125
    • Ronnov-Jessen, L.1    Petersen, O.W.2    Bissell, M.J.3
  • 39
    • 3342910234 scopus 로고    scopus 로고
    • FAK and paxillin: Regulators of N-cadherin adhesion and inhibitors of cell migration?
    • Schaller MD. FAK and paxillin: regulators of N-cadherin adhesion and inhibitors of cell migration? J Cell Biol 166: 157-159, 2004.
    • (2004) J Cell Biol , vol.166 , pp. 157-159
    • Schaller, M.D.1
  • 40
    • 22344434300 scopus 로고    scopus 로고
    • Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis
    • Shen TL, Park AY, Alcaraz A, Peng X, Jang I, Koni P, Flavell RA, Gu H, Guan JL. Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis. J Cell Biol 169: 941-952, 2005.
    • (2005) J Cell Biol , vol.169 , pp. 941-952
    • Shen, T.L.1    Park, A.Y.2    Alcaraz, A.3    Peng, X.4    Jang, I.5    Koni, P.6    Flavell, R.A.7    Gu, H.8    Guan, J.L.9
  • 41
    • 33745808765 scopus 로고    scopus 로고
    • Transforming growth factor beta: A central modulator of pulmonary and airway inflammation and fibrosis
    • Sheppard D. Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis. Proc Am Thorac Soc 3: 413-417, 2006.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 413-417
    • Sheppard, D.1
  • 43
    • 0037084459 scopus 로고    scopus 로고
    • N-WASP activation by a beta1-integrin-dependent mechanism supports PI3K-independent chemotaxis stimulated by urokinase-type plasminogen activator
    • Sturge J, Hamelin J, Jones GE. N-WASP activation by a beta1-integrin-dependent mechanism supports PI3K-independent chemotaxis stimulated by urokinase-type plasminogen activator. J Cell Sci 115: 699-711, 2002.
    • (2002) J Cell Sci , vol.115 , pp. 699-711
    • Sturge, J.1    Hamelin, J.2    Jones, G.E.3
  • 44
    • 0034983715 scopus 로고    scopus 로고
    • WASP and WAVE family proteins: Key molecules for rapid rearrangement of cortical action filaments and cell movement
    • Takenawa T, Miki H. WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical action filaments and cell movement. J Cell Sci 114: 1801-1809, 2001.
    • (2001) J Cell Sci , vol.114 , pp. 1801-1809
    • Takenawa, T.1    Miki, H.2
  • 45
    • 33845729059 scopus 로고    scopus 로고
    • The WASP-WAVE protein network: Connecting the membrane to the cytoskeleton
    • Takenawa T, Suetsugu S. The WASP-WAVE protein network: connecting the membrane to the cytoskeleton. Nat Rev Mol Cell Biol 8: 37-48, 2007.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 37-48
    • Takenawa, T.1    Suetsugu, S.2
  • 46
    • 0038823614 scopus 로고    scopus 로고
    • Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase
    • Thannickal VJ, Lee DY, White ES, Cui Z, Larios JM, Chacon R, Horowitz JC, Day RM, Thomas PE. Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase. J Biol Chem 278: 12384-12389, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 12384-12389
    • Thannickal, V.J.1    Lee, D.Y.2    White, E.S.3    Cui, Z.4    Larios, J.M.5    Chacon, R.6    Horowitz, J.C.7    Day, R.M.8    Thomas, P.E.9
  • 48
    • 0033231935 scopus 로고    scopus 로고
    • The world according to Arp: Regulation of action nucleation by the Arp2/3 complex
    • Welch MD. The world according to Arp: regulation of action nucleation by the Arp2/3 complex. Trends Cell Biol 9: 423-427, 1999.
    • (1999) Trends Cell Biol , vol.9 , pp. 423-427
    • Welch, M.D.1
  • 49
    • 37249044357 scopus 로고    scopus 로고
    • Myofibroblast contraction activates latent TGF-beta1 from the extra cellular matrix
    • Wipff PJ, Rifkin DB, Meister JJ, Hinz B. Myofibroblast contraction activates latent TGF-beta1 from the extra cellular matrix. J Cell Biol 179: 1311-1323, 2007.
    • (2007) J Cell Biol , vol.179 , pp. 1311-1323
    • Wipff, P.J.1    Rifkin, D.B.2    Meister, J.J.3    Hinz, B.4
  • 50
    • 1542304700 scopus 로고    scopus 로고
    • Focal adhesion kinase regulation of N-WASP sub cellular localization and function
    • Wu X, Suetsugu S, Cooper LA, Takenawa T, Guan JL. Focal adhesion kinase regulation of N-WASP sub cellular localization and function. J Biol Chem 279: 9565-9576, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 9565-9576
    • Wu, X.1    Suetsugu, S.2    Cooper, L.A.3    Takenawa, T.4    Guan, J.L.5
  • 51
    • 33744953676 scopus 로고    scopus 로고
    • Interaction of N-WASP with hnRNPK and its role in filopodia formation and cell spreading
    • Yoo Y, Wu X, Egile C, Li R, Guan JL. Interaction of N-WASP with hnRNPK and its role in filopodia formation and cell spreading. J Biol Chem 281: 15352-15360, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 15352-15360
    • Yoo, Y.1    Wu, X.2    Egile, C.3    Li, R.4    Guan, J.L.5
  • 52
    • 79951680622 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha regulates the Hypocretin system via mRNA degradation and ubiquitination
    • Zhan S, Cai GQ, Zheng A, Wang Y, Jia J, Fang H, Yang Y, Hu M, Ding Q. Tumor necrosis factor-alpha regulates the Hypocretin system via mRNA degradation and ubiquitination. Biochim Biophys Acta 1812: 565-571, 2011.
    • (2011) Biochim Biophys Acta , vol.1812 , pp. 565-571
    • Zhan, S.1    Cai, G.Q.2    Zheng, A.3    Wang, Y.4    Jia, J.5    Fang, H.6    Yang, Y.7    Hu, M.8    Ding, Q.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.