Profound conformational changes of PED/PEA-15 in ERK2 complex revealed by NMR backbone dynamics

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1824, Issue 12, 2012, Pages 1382-1393

  Twomey, Edward C ^a   Cordasco, Dana F ^a   Wei, Yufeng ^a,b  

^a SETON HALL UNIVERSITY   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Death effector domain; ERK2; MAP kinase; NMR dynamics; PED PEA 15

Indexed keywords

FAS ASSOCIATED DEATH DOMAIN PROTEIN; GROWTH FACTOR; HORMONE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROTRANSMITTER; PHOSPHOPROTEIN; PROCASPASE 8; PROTEIN PED; PROTEIN PLD1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANALYTIC METHOD; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CYTOPLASM; CYTOSOL; DYNAMICS; ENZYME ACTIVATION; ENZYME IMMOBILIZATION; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; MOLECULAR MODEL; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM;

AMINO ACID SEQUENCE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAGNETIC RESONANCE SPECTROSCOPY; MITOGEN-ACTIVATED PROTEIN KINASE 1; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEINS; PROTEIN CONFORMATION;

MAMMALIA;

EID: 84867680319     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2012.07.001     Document Type: Article

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