Fractal dimension as a measure of surface roughness of G protein-coupled receptors: Implications for structure and function

Journal of Molecular Modeling

Volumn 18, Issue 9, 2012, Pages 4465-4475

  Kaczor, Agnieszka A ^a,b   Guixà González, Ramon ^a   Carrió, Pau ^a   Obiol Pardo, Cristian ^a,c   Pastor, Manuel ^a   Selent, Jana ^a  

^a Barcelona Biomedical Research Park   (Spain)

^b MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^c Intelligent Pharma   (Spain)

Author keywords

Fractal geometry; G protein coupled receptors; Ligand binding; Membrane cholesterol; Surface roughness

Indexed keywords

ALPRENOLOL; BETA 2 ADRENERGIC RECEPTOR; CARAZOLOL; G PROTEIN COUPLED RECEPTOR; PROTEIN PATCHED; TIMOLOL;

ARTICLE; CALCULATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG TARGETING; FRACTAL ANALYSIS; GEOMETRY; LIGAND BINDING; PERIODICITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SURFACE PROPERTY; SURFACE ROUGHNESS;

BINDING SITES; CHOLESTEROL; FRACTALS; MODELS, MOLECULAR; PROTEIN CONFORMATION; RECEPTORS, ADRENERGIC, BETA-2; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PROPERTIES;

EID: 84867576743     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-012-1431-2     Document Type: Article

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