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ChemPhysChem

Volumn 13, Issue 15, 2012, Pages 3472-3480

On-bead screens sample narrower affinity ranges of protein-ligand interactions compared to equivalent solution assays

(3) Hintersteiner, Martin a,b Buehler, Christof c Auer, Manfred a

a UNIVERSITY OF EDINBURGH (United Kingdom)

b Succursale di Lugano (Switzerland)

c Supercomputing Systems AG (Switzerland)

Author keywords

combinatorial chemistry; high throughput screening; kinetics; molecular recognition; thermodynamics

Indexed keywords

BINDERS; BIOCHEMISTRY; BIOCHIPS; COST EFFECTIVENESS; DIGITAL STORAGE; DISSOCIATION; ENZYME KINETICS; EQUILIBRIUM CONSTANTS; KINETICS; MOLECULAR RECOGNITION; MOLECULES; PROTEINS; RATE CONSTANTS; THERMODYNAMIC PROPERTIES; THERMODYNAMICS;

BIOPHYSICAL CHARACTERIZATION; COMBINATORIAL CHEMISTRY; COST-EFFECTIVE METHODS; HIGH THROUGHPUT SCREENING; KINETIC AND THERMODYNAMIC PROPERTIES; KINETICS AND THERMODYNAMICS; PROTEIN-LIGAND INTERACTIONS; QUANTITATIVE COMPARISON;

LIGANDS;

EID: 84867546573 PISSN: 14394235 EISSN: 14397641 Source Type: Journal
DOI: 10.1002/cphc.201200117 Document Type: Article

Times cited : (20)

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