Isolation of Antagonists of Antigen-Specific Autoimmune T Cell Proliferation

Chemistry and Biology

Volumn 16, Issue 11, 2009, Pages 1133-1139

  Gocke, Anne R ^a,b   Udugamasooriya, D Gomika ^a,b   Archer, Chase T ^a,b   Lee, Jiyong ^a,b   Kodadek, Thomas ^c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

CHEMBIO

Indexed keywords

MYELIN BASIC PROTEIN; MYELIN BASIC PROTEIN 1 11; MYELIN BASIC PROTEIN 1-11; PEPTIDE FRAGMENT; PEPTIDE LIBRARY; PEPTOID;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL; ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG EFFECT; FEMALE; FLOW CYTOMETRY; IMMUNOLOGY; METABOLISM; MOUSE; TRANSGENIC MOUSE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; COMBINATORIAL CHEMISTRY TECHNIQUES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; FLOW CYTOMETRY; MICE; MICE, TRANSGENIC; MYELIN BASIC PROTEINS; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY; PEPTOIDS;

MURINAE;

EID: 72049105305     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2009.10.011     Document Type: Article

References (18)

1. Alluri P.G., Reddy M.M., Bachhawat-Sikder K., Olivos H.J., and Kodadek T. Isolation of protein ligands from large peptoid libraries. J. Am. Chem. Soc. 125 (2003) 13995-14004
2. Ando D.G., Clayton J., Kono D., Urban J.L., and Sercarz E.E. Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype. Cell. Immunol. 124 (1989) 132-143
3. Besnier D.P., Chabannes D., Mussini J.M., Dupas B., and Esnault V.L. Extracorporeal photochemotherapy for secondary chronic progressive multiple sclerosis: a pilot study. Photodermatol. Photoimmunol. Photomed. 18 (2002) 36-41
4. Burdine L., Gillette T.G., Lin H.-J., and Kodadek T. Periodate-triggered cross-linking of DOPA-containing peptide-protein complexes. J. Am. Chem. Soc. 126 (2004) 11442-11443
5. Cavaletti G., Perseghin P., Dassi M., Cavarretta R., Frigo M., Caputo D., Stanzani L., Tagliabue E., Zoia C., Grimaldi M., et al. Extracorporeal photochemotherapy: a safety and tolerability pilot study with preliminary efficacy results in refractory relapsing-remitting multiple sclerosis. Neurol. Sci. 27 (2006) 24-32
6. Goverman J., Woods A., Larson L., Weiner L.P., Hood L., and Zaller D.M. Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Cell 72 (1993) 551-560
7. Hemmer B., and Hartung H.P. Toward the development of rational therapies in multiple sclerosis: what is on the horizon?. Ann. Neurol. 62 (2007) 314-326
8. Kodadek T., Reddy M.M., Olivos H.J., Bachhawat-Sikder K., and Alluri P.G. Synthetic molecules as antibody replacements. Acc. Chem. Res. 37 (2004) 711-718
9. Lee J., Yu P., Xiao X., and Kodadek T. A general system for evaluating the efficiency of chromophore-assisted light inactivation (CALI) of proteins reveals Ru(II) tris-bipyridyl as an unusually efficient "warhead". Mol. Biosyst. 4 (2008) 59-65
10. Lim H.-S., Cai D., Archer C., and Kodadek T. Periodate-triggered cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle. J. Am. Chem. Soc. 129 (2007) 12936-12937
11. Liu B., Burdine L., and Kodadek T. Chemistry of periodate-mediated cross-linking of 3,4-dihydroxylphenylalanine (DOPA)-containing molecules to proteins. J. Am. Chem. Soc. 128 (2006) 15228-15235
12. Noseworthy J.H., Lucchinetti C., Rodriguez M., and Weinshenker B.G. Multiple sclerosis. N. Engl. J. Med. 343 (2000) 938-952
13. Olivos H.J., Alluri P.G., Reddy M.M., Saloney D., and Kodadek T. Microwave-assisted solid-phase synthesis of peptoids. Org. Lett. 4 (2002) 4057-4059
14. Racke M.K. Experimental autoimmune encephalomyelitis (EAE). Curr. Protoc. Neurosci. 9 (2001) Unit9.7
15. Rostami A.M., Sater R.A., Bird S.J., Galetta S., Farber R.E., Kamoun M., Silberberg D.H., Grossman R.I., and Pfohl D. A double-blind, placebo-controlled trial of extracorporeal photopheresis in chronic progressive multiple sclerosis. Mult. Scler. 5 (1999) 198-203
16. Simon R.J., Kania R.S., Zuckermann R.N., Huebner V.D., Jewell D.A., Banville S., Ng S., Wang L., Rosenberg S., Marlowe C.K., et al. Peptoids: a modular approach to drug discovery. Proc. Natl. Acad. Sci. USA 89 (1992) 9367-9371
17. Udugamasooriya D.G., Dineen S.P., Brekken R.A., and Kodadek T. A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity. J. Am. Chem. Soc. 130 (2008) 5744-5752
18. Zamvil S.S., and Steinman L. The T lymphocyte in experimental allergic encephalomyelitis. Annu. Rev. Immunol. 8 (1990) 579-621