Comparison of resin and solution screening methodologies in combinatorial chemistry and the identification of a 100 nM inhibitor of trypanothione reductase

Journal of Combinatorial Chemistry

Volumn 1, Issue 4, 1999, Pages 326-332

  Smith, Helen K ^a   Bradley, Mark ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITRYPANOSOMAL AGENT; ENZYME INHIBITOR; OXIDOREDUCTASE; PEPTIDE LIBRARY; PLANT RESIN; POLYAMINE; TRYPANOTHIONE REDUCTASE;

ARTICLE; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; METHODOLOGY; SOLUTION AND SOLUBILITY; SYNTHESIS;

COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; ENZYME INHIBITORS; NADH, NADPH OXIDOREDUCTASES; PEPTIDE LIBRARY; POLYAMINES; RESINS, PLANT; SOLUTIONS; TRYPANOCIDAL AGENTS;

EID: 0033155999     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc990013c     Document Type: Article

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