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Volumn 12, Issue 15, 2012, Pages 1621-1629

Development of nucleic acid drugs for neurological disorders

Author keywords

Alzheimer disease; Cerebral ischemia; Diabetic neuropathy; DNA vaccine; Multiple sclerosis; NF B decoy; Nucleic acid drug; Plasmid DNA

Indexed keywords

ALZHEIMER DISEASE VACCINE; AMYLOID BETA PROTEIN[1-42]; ATORVASTATIN; BHT 3009; CENTRAL NERVOUS SYSTEM AGENTS; DNA VACCINE; MYELIN BASIC PROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; NUCLEAR FACTOR KAPPA B DECOY; PERFLUBUTANE; PERFLUTREN; PLASMID DNA; RECOMBINANT SCATTER FACTOR; RECOMBINANT VASCULOTROPIN; SCATTER FACTOR; SHU 508; SONOVUE; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN 165; VASCULOTROPIN A; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR 1;

EID: 84867535779     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/156802612803531405     Document Type: Review
Times cited : (4)

References (83)
  • 1
    • 33748329461 scopus 로고    scopus 로고
    • Gene transfer of an engineered transcription factor promoting expression of VEGF-A protects against experimental diabetic neuropathy
    • Price, S.A.; Dent, C.; Duran-Jimenez, B.; Liang, Y.; Zhang, L.; Rebar, E.J. Gene transfer of an engineered transcription factor promoting expression of VEGF-A protects against experimental diabetic neuropathy. Diabetes, 2006, 55, 1847-54.
    • (2006) Diabetes , vol.55 , pp. 1847-1854
    • Price, S.A.1    Dent, C.2    Duran-Jimenez, B.3    Liang, Y.4    Zhang, L.5    Rebar, E.J.6
  • 2
    • 0035839531 scopus 로고    scopus 로고
    • VEGF gene transfer for diabetic neuropathy
    • Isner, J.M.; Ropper, A.; Hirst, K. VEGF gene transfer for diabetic neuropathy. Hum. Gene. Ther., 2001, 12, 1593-1594.
    • (2001) Hum. Gene. Ther , vol.12 , pp. 1593-1594
    • Isner, J.M.1    Ropper, A.2    Hirst, K.3
  • 3
    • 0036113988 scopus 로고    scopus 로고
    • Gene transfer of hepatocyte growth factor to subarachnoid space in cerebral hypoperfusion model
    • Yoshimura, S.; Morishita, R.; Hayashi, K.; Kokuzawa, J.; Aoki, M.; Matsumoto, K. Gene transfer of hepatocyte growth factor to subarachnoid space in cerebral hypoperfusion model. Hypertension. 2002, 39, 1028-1034.
    • (2002) Hypertension , vol.39 , pp. 1028-1034
    • Yoshimura, S.1    Morishita, R.2    Hayashi, K.3    Kokuzawa, J.4    Aoki, M.5    Matsumoto, K.6
  • 4
    • 17944375146 scopus 로고    scopus 로고
    • Gene therapy for preventing neuronal death using hepatocyte growth factor: In vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons
    • Hayashi, K.; Morishita, R.; Nakagami, H.; Yoshimura, S.; Hara, A.; Matsumoto, K. Gene therapy for preventing neuronal death using hepatocyte growth factor: in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons. Gene Ther., 2001, 8, 1167-1173.
    • (2001) Gene Ther , vol.8 , pp. 1167-1173
    • Hayashi, K.1    Morishita, R.2    Nakagami, H.3    Yoshimura, S.4    Hara, A.5    Matsumoto, K.6
  • 5
    • 65649114702 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene transfer for diabetic polyneuropathy: A randomized, double-blinded trial
    • Ropper, A.H.; Gorson, K.C.; Gooch, C.L. Weinberg, D.H.; Pieczek, A.; Ware, J.H. Vascular endothelial growth factor gene transfer for diabetic polyneuropathy: a randomized, double-blinded trial. Ann Neurol., 2009, 65, 386-393.
    • (2009) Ann Neurol , vol.65 , pp. 386-393
    • Ropper, A.H.1    Gorson, K.C.2    Gooch, C.L.3    Weinberg, D.H.4    Pieczek, A.5    Ware, J.H.6
  • 6
    • 52449100395 scopus 로고    scopus 로고
    • Quantitative MR measurements of regional and global left ventricular function and strain after intramyocardial transfer of VM202 into infarcted swine myocardium
    • Carlsson, M.; Osman, N.F.; Ursell, P.C.; Martin, A.J.; Saeed, M. Quantitative MR measurements of regional and global left ventricular function and strain after intramyocardial transfer of VM202 into infarcted swine myocardium. Am. J. Physiol. Heart Circ. Physiol., 2008, 295, H522-532.
    • (2008) Am. J. Physiol. Heart Circ. Physiol , vol.295
    • Carlsson, M.1    Osman, N.F.2    Ursell, P.C.3    Martin, A.J.4    Saeed, M.5
  • 8
    • 0035497348 scopus 로고    scopus 로고
    • Nuclear factor-kappa B decoy attenuates neuronal damage after global brain ischemia: A future strategy for brain protection during circulatory arrest
    • Ueno, T.; Sawa, Y.; Kitagawa-Sakakida, S.; Nishimura, M.; Morishita, R.; Kaneda, Y. Nuclear factor-kappa B decoy attenuates neuronal damage after global brain ischemia: a future strategy for brain protection during circulatory arrest. J. Thorac. Cardiovasc. Surg., 2001, 122, 720-727.
    • (2001) J. Thorac. Cardiovasc. Surg , vol.122 , pp. 720-727
    • Ueno, T.1    Sawa, Y.2    Kitagawa-Sakakida, S.3    Nishimura, M.4    Morishita, R.5    Kaneda, Y.6
  • 11
    • 10044263401 scopus 로고    scopus 로고
    • Gene vaccination to bias the immune response to amyloid-beta peptide as therapy for Alzheimer disease
    • Qu, B.; Rosenberg, R.N.; Li, L.; Boyer, P.J.; Johnston, S.A. Gene vaccination to bias the immune response to amyloid-beta peptide as therapy for Alzheimer disease. Arch Neurol., 2004, 61, 1859-1864.
    • (2004) Arch Neurol , vol.61 , pp. 1859-1864
    • Qu, B.1    Rosenberg, R.N.2    Li, L.3    Boyer, P.J.4    Johnston, S.A.5
  • 12
    • 47749107621 scopus 로고    scopus 로고
    • Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy
    • Movsesyan, N.; Ghochikyan, A.; Mkrtichyan, M.; Petrushina, I.; Davtyan, H.; Olkhanud, P.B. Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy. PLoS One, 2008, 3, e2124.
    • (2008) PLoS One , vol.3
    • Movsesyan, N.1    Ghochikyan, A.2    Mkrtichyan, M.3    Petrushina, I.4    Davtyan, H.5    Olkhanud, P.B.6
  • 13
    • 33646524039 scopus 로고    scopus 로고
    • Abeta42 gene vaccination reduces brain amyloid plaque burden in transgenic mice
    • Qu, B.; Boyer, P.J.; Johnston, S.A.; Hynan, L.S.; Rosenberg, R. N. Abeta42 gene vaccination reduces brain amyloid plaque burden in transgenic mice. J. Neurol. Sci., 2006, 244, 151-158.
    • (2006) J. Neurol. Sci , vol.244 , pp. 151-158
    • Qu, B.1    Boyer, P.J.2    Johnston, S.A.3    Hynan, L.S.4    Rosenberg, R.N.5
  • 14
    • 84856232262 scopus 로고    scopus 로고
    • DNA-based vaccines for multiple sclerosis: Current status and future directions
    • Fissolo, N.; Montalban, X.; Comabella, M. DNA-based vaccines for multiple sclerosis: Current status and future directions. Clin. Immunol., 2012, 142(1), 76-83.
    • (2012) Clin. Immunol , vol.142 , Issue.1 , pp. 76-83
    • Fissolo, N.1    Montalban, X.2    Comabella, M.3
  • 15
    • 0032482187 scopus 로고    scopus 로고
    • Vaccination with DNA encoding an immunodominant myelin basic protein peptide targeted to Fc of immunoglobulin G suppresses experimental autoimmune encephalomyelitis
    • Lobell, A.; Weissert, R.; Storch, M.K.; Svanholm, C.; de Graaf, K.L.; Lassmann, H. Vaccination with DNA encoding an immunodominant myelin basic protein peptide targeted to Fc of immunoglobulin G suppresses experimental autoimmune encephalomyelitis. J. Exp. Med., 1998, 187, 1543-1548.
    • (1998) J. Exp. Med , vol.187 , pp. 1543-1548
    • Lobell, A.1    Weissert, R.2    Storch, M.K.3    Svanholm, C.4    de Graaf, K.L.5    Lassmann, H.6
  • 16
    • 0034652209 scopus 로고    scopus 로고
    • Protective DNA vaccination against organ-specific autoimmunity is highly specific and discriminates between single amino acid substitutions in the peptide autoantigen
    • Weissert, R.; Lobell, A.; de Graaf, K.L.; Eltayeb, S.Y.; Andersson, R.; Olsson, T. Protective DNA vaccination against organ-specific autoimmunity is highly specific and discriminates between single amino acid substitutions in the peptide autoantigen. Proc. Natl. Acad. Sci. U S A, 2000, 97, 1689-1694.
    • (2000) Proc. Natl. Acad. Sci. U S A , vol.97 , pp. 1689-1694
    • Weissert, R.1    Lobell, A.2    de Graaf, K.L.3    Eltayeb, S.Y.4    Andersson, R.5    Olsson, T.6
  • 17
    • 0037442140 scopus 로고    scopus 로고
    • Suppressive DNA vaccination in myelin oligodendrocyte glycoprotein peptide-induced experimental autoimmune encephalomyelitis involves a T1-biased immune response
    • Lobell, A.; Weissert, R.; Eltayeb, S.; de Graaf, K.L.; Wefer, J.; Storch, M.K. Suppressive DNA vaccination in myelin oligodendrocyte glycoprotein peptide-induced experimental autoimmune encephalomyelitis involves a T1-biased immune response. J. Immunol., 2003, 170, 1806-1813.
    • (2003) J. Immunol , vol.170 , pp. 1806-1813
    • Lobell, A.1    Weissert, R.2    Eltayeb, S.3    de Graaf, K.L.4    Wefer, J.5    Storch, M.K.6
  • 18
    • 0032710319 scopus 로고    scopus 로고
    • Clinical applications of angiogenic growth factors and their inhibitors
    • Ferrara, N.; Alitalo, K. Clinical applications of angiogenic growth factors and their inhibitors. Nat. Med., 1999, 5, 1359-1364.
    • (1999) Nat. Med , vol.5 , pp. 1359-1364
    • Ferrara, N.1    Alitalo, K.2
  • 19
    • 2342667384 scopus 로고    scopus 로고
    • New roles for VEGF in nervous tissue--beyond blood vessels
    • Rosenstein, J.M.; Krum, J.M. New roles for VEGF in nervous tissue--beyond blood vessels. Exp. Neurol., 2004, 187, 246-253.
    • (2004) Exp. Neurol , vol.187 , pp. 246-253
    • Rosenstein, J.M.1    Krum, J.M.2
  • 21
    • 33745277087 scopus 로고    scopus 로고
    • VEGF 164 gene transfer by electroporation improves diabetic sensory neuropathy in mice
    • Murakami, T.; Arai, M.; Sunada, Y.; Nakamura, A. VEGF 164 gene transfer by electroporation improves diabetic sensory neuropathy in mice. J. Gene Med., 2006, 8, 773-781.
    • (2006) J. Gene Med , vol.8 , pp. 773-781
    • Murakami, T.1    Arai, M.2    Sunada, Y.3    Nakamura, A.4
  • 22
    • 0021285134 scopus 로고
    • Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats
    • Nakamura, T.; Nawa, K.; Ichihara, A. Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats. Biochem. Biophys. Res. Commun., 1984, 122, 1450-1459.
    • (1984) Biochem. Biophys. Res. Commun , vol.122 , pp. 1450-1459
    • Nakamura, T.1    Nawa, K.2    Ichihara, A.3
  • 24
    • 0029142780 scopus 로고
    • Localization and functional coupling of HGF and c-Met/HGF receptor in rat brain: Implication as neurotrophic factor
    • Honda, S.; Kagoshima, M.; Wanaka, A.; Tohyama, M.; Matsumoto, K.; Nakamura, T. Localization and functional coupling of HGF and c-Met/HGF receptor in rat brain: implication as neurotrophic factor. Brain Res. Mol. Brain Res., 1995, 32, 197-210.
    • (1995) Brain Res. Mol. Brain Res , vol.32 , pp. 197-210
    • Honda, S.1    Kagoshima, M.2    Wanaka, A.3    Tohyama, M.4    Matsumoto, K.5    Nakamura, T.6
  • 25
    • 0028308229 scopus 로고
    • Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain
    • Jung, W.; Castren, E.; Odenthal, M.; Vande Woude, G.F.; Ishii, T.; Dienes, H.P. Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain. J. Cell Biol., 1994, 126, 485-494.
    • (1994) J. Cell Biol , vol.126 , pp. 485-494
    • Jung, W.1    Castren, E.2    Odenthal, M.3    van de Woude, G.F.4    Ishii, T.5    Dienes, H.P.6
  • 26
    • 0034651876 scopus 로고    scopus 로고
    • Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol-3 kinase/Akt pathway
    • Zhang, L.; Himi, T.; Morita, I.; Murota, S. Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol-3 kinase/Akt pathway. J. Neurosci. Res., 2000, 59, 489-496.
    • (2000) J. Neurosci. Res , vol.59 , pp. 489-496
    • Zhang, L.1    Himi, T.2    Morita, I.3    Murota, S.4
  • 27
    • 0036316595 scopus 로고    scopus 로고
    • Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase/aktdependent and MAPK/CREB-independent
    • Hossain, M.A.; Russell, J.C.; Gomez, R.; Laterra, J. Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase/aktdependent and MAPK/CREB-independent. J. Neurochem., 2002, 81, 365-378.
    • (2002) J. Neurochem , vol.81 , pp. 365-378
    • Hossain, M.A.1    Russell, J.C.2    Gomez, R.3    Laterra, J.4
  • 28
    • 0037387794 scopus 로고    scopus 로고
    • Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene
    • Koike, H.; Morishita, R.; Iguchi, S.; Aoki, M.; Matsumoto, K.; Nakamura, T. Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene. FASEB J., 2003, 17, 779-781.
    • (2003) FASEB J , vol.17 , pp. 779-781
    • Koike, H.1    Morishita, R.2    Iguchi, S.3    Aoki, M.4    Matsumoto, K.5    Nakamura, T.6
  • 29
    • 14644396138 scopus 로고    scopus 로고
    • Nonviral gene transfer of human hepatocyte growth factor improves streptozotocin-induced diabetic neuropathy in rats
    • Kato, N.; Nemoto, K.; Nakanishi, K.; Morishita, R.; Kaneda, Y.; Uenoyama, M. Nonviral gene transfer of human hepatocyte growth factor improves streptozotocin-induced diabetic neuropathy in rats. Diabetes, 2005, 54, 846-854.
    • (2005) Diabetes , vol.54 , pp. 846-854
    • Kato, N.1    Nemoto, K.2    Nakanishi, K.3    Morishita, R.4    Kaneda, Y.5    Uenoyama, M.6
  • 30
    • 53749100318 scopus 로고    scopus 로고
    • MR assessment of myocardial perfusion, viability, and function after intramyocardial transfer of VM202, a new plasmid human hepatocyte growth factor in ischemic swine myocardium
    • Saeed, M.; Martin, A.; Ursell, P.; Do, L.; Bucknor, M.; Higgins, C.B. MR assessment of myocardial perfusion, viability, and function after intramyocardial transfer of VM202, a new plasmid human hepatocyte growth factor in ischemic swine myocardium. Radiology, 2008, 249, 107-118.
    • (2008) Radiology , vol.249 , pp. 107-118
    • Saeed, M.1    Martin, A.2    Ursell, P.3    Do, L.4    Bucknor, M.5    Higgins, C.B.6
  • 31
    • 0000135127 scopus 로고    scopus 로고
    • Protection of hippocampal neurons from ischemia-induced delayed neuronal death by hepatocyte growth factor: A novel neurotrophic factor
    • Miyazawa, T.; Matsumoto, K.; Ohmichi, H.; Katoh, H.; Yamashima, T.; Nakamura, T. Protection of hippocampal neurons from ischemia-induced delayed neuronal death by hepatocyte growth factor: a novel neurotrophic factor. J. Cereb. Blood Flow Metab., 1998, 18, 345-348.
    • (1998) J. Cereb. Blood Flow Metab , vol.18 , pp. 345-348
    • Miyazawa, T.1    Matsumoto, K.2    Ohmichi, H.3    Katoh, H.4    Yamashima, T.5    Nakamura, T.6
  • 32
    • 0034967770 scopus 로고    scopus 로고
    • Hepatocyte growth factor reduces the infarct volume after transient focal cerebral ischemia in rats
    • Tsuzuki, N.; Miyazawa, T.; Matsumoto, K.; Nakamura, T.; Shima, K. Hepatocyte growth factor reduces the infarct volume after transient focal cerebral ischemia in rats. Neurol. Res., 2001, 23, 417-424.
    • (2001) Neurol. Res , vol.23 , pp. 417-424
    • Tsuzuki, N.1    Miyazawa, T.2    Matsumoto, K.3    Nakamura, T.4    Shima, K.5
  • 33
    • 0041743159 scopus 로고    scopus 로고
    • VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia
    • Sun, Y.; Jin, K.; Xie, L.; Childs, J.; Mao, X.O.; Logvinova, A. VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia. J. Clin. Invest., 2003, 111, 1843-1851.
    • (2003) J. Clin. Invest , vol.111 , pp. 1843-1851
    • Sun, Y.1    Jin, K.2    Xie, L.3    Childs, J.4    Mao, X.O.5    Logvinova, A.6
  • 34
    • 0033797255 scopus 로고    scopus 로고
    • VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain
    • Zhang, Z.G.; Zhang, L.; Jiang, Q.; Zhang, R.; Davies, K.; Powers, C. VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain. J. Clin. Invest., 2000, 106, 829-838.
    • (2000) J. Clin. Invest , vol.106 , pp. 829-838
    • Zhang, Z.G.1    Zhang, L.2    Jiang, Q.3    Zhang, R.4    Davies, K.5    Powers, C.6
  • 35
    • 0032950983 scopus 로고    scopus 로고
    • Effective administration route for the deleted form of hepatocyte growth factor To exert its pharmacological effects
    • Uematsu, Y.; Fujise, N.; Kohsaka, K.; Masunaga, H.; Higashio, K. Effective administration route for the deleted form of hepatocyte growth factor To exert its pharmacological effects. J. Pharm. Sci., 1999, 88, 131-135.
    • (1999) J. Pharm. Sci , vol.88 , pp. 131-135
    • Uematsu, Y.1    Fujise, N.2    Kohsaka, K.3    Masunaga, H.4    Higashio, K.5
  • 36
    • 9144265425 scopus 로고    scopus 로고
    • Novel therapeutic strategy to treat brain ischemia: Overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model
    • Shimamura, M.; Sato, N.; Oshima, K.; Aoki, M.; Kurinami, H.; Waguri, S. Novel therapeutic strategy to treat brain ischemia: overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model. Circulation, 2004, 109, 424-431.
    • (2004) Circulation , vol.109 , pp. 424-431
    • Shimamura, M.1    Sato, N.2    Oshima, K.3    Aoki, M.4    Kurinami, H.5    Waguri, S.6
  • 37
    • 33645835919 scopus 로고    scopus 로고
    • Gene transfer of hepatocyte growth factor gene improves learning and memory in the chronic stage of cerebral infarction
    • Shimamura, M.; Sato, N.; Waguri, S.; Uchiyama, Y.; Hayashi, T.; Iida, H. Gene transfer of hepatocyte growth factor gene improves learning and memory in the chronic stage of cerebral infarction. Hypertension, 2006, 47, 742-751.
    • (2006) Hypertension , vol.47 , pp. 742-751
    • Shimamura, M.1    Sato, N.2    Waguri, S.3    Uchiyama, Y.4    Hayashi, T.5    Iida, H.6
  • 38
    • 54049097850 scopus 로고    scopus 로고
    • Cell death and proliferation in NF-kappaB p50 knockout mouse after cerebral ischemia
    • Li, J.; Lu, Z.; Li, W.L.; Yu, S.P.; Wei, L. Cell death and proliferation in NF-kappaB p50 knockout mouse after cerebral ischemia. Brain Res., 2008, 1230, 281-289.
    • (2008) Brain Res , vol.1230 , pp. 281-289
    • Li, J.1    Lu, Z.2    Li, W.L.3    Yu, S.P.4    Wei, L.5
  • 39
    • 33646558596 scopus 로고    scopus 로고
    • NF-kappaB protects neurons from ischemic injury after middle cerebral artery occlusion in mice
    • Duckworth, E.A.; Butler, T.; Collier, L.; Collier, S.; Pennypacker, K. R. NF-kappaB protects neurons from ischemic injury after middle cerebral artery occlusion in mice. Brain Res., 2006, 1088, 167-175.
    • (2006) Brain Res , vol.1088 , pp. 167-175
    • Duckworth, E.A.1    Butler, T.2    Collier, L.3    Collier, S.4    Pennypacker, K.R.5
  • 40
    • 78149259667 scopus 로고
    • NF-kappaB and innate immunity in ischemic stroke
    • Harari, O.A.; Liao, J.K. NF-kappaB and innate immunity in ischemic stroke. Ann. N. Y. Acad. Sci., 1207, 32-40.
    • (1207) Ann. N. Y. Acad. Sci , pp. 32-40
    • Harari, O.A.1    Liao, J.K.2
  • 41
    • 0142210080 scopus 로고    scopus 로고
    • Gene transfer with echoenhanced contrast agents: Comparison between Albunex, Optison, and Levovist in mice--initial results
    • Li, T.; Tachibana, K.; Kuroki, M. Gene transfer with echoenhanced contrast agents: comparison between Albunex, Optison, and Levovist in mice--initial results. Radiology, 2003, 229, 423-428.
    • (2003) Radiology , vol.229 , pp. 423-428
    • Li, T.1    Tachibana, K.2    Kuroki, M.3
  • 42
    • 27944474332 scopus 로고    scopus 로고
    • Gene transfer into adult rat spinal cord using naked plasmid DNA and ultrasound microbubbles
    • Shimamura, M.; Sato, N.; Taniyama, Y.; Kurinami, H.; Tanaka, H.; Takami, T. Gene transfer into adult rat spinal cord using naked plasmid DNA and ultrasound microbubbles. J. Gene Med., 2005, 7, 1468-1474.
    • (2005) J. Gene Med , vol.7 , pp. 1468-1474
    • Shimamura, M.1    Sato, N.2    Taniyama, Y.3    Kurinami, H.4    Tanaka, H.5    Takami, T.6
  • 43
    • 0036113958 scopus 로고    scopus 로고
    • Fetal gene transfer by intrauterine injection with micro- bubble-enhanced ultrasound
    • Endoh, M.; Koibuchi, N.; Sato, M.; Morishita, R.; Kanzaki, T.; Murata, Y. Fetal gene transfer by intrauterine injection with micro- bubble-enhanced ultrasound. Mol. Ther., 2002, 5, 501-508.
    • (2002) Mol. Ther , vol.5 , pp. 501-508
    • Endoh, M.1    Koibuchi, N.2    Sato, M.3    Morishita, R.4    Kanzaki, T.5    Murata, Y.6
  • 44
    • 0036227368 scopus 로고    scopus 로고
    • Development of safe and efficient novel nonviral gene transfer using ultrasound: Enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle
    • Taniyama, Y.; Tachibana, K.; Hiraoka, K.; Aoki, M.; Yamamoto, S.; Matsumoto, K. Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle. Gene Ther., 2002, 9, 372-380.
    • (2002) Gene Ther , vol.9 , pp. 372-380
    • Taniyama, Y.1    Tachibana, K.2    Hiraoka, K.3    Aoki, M.4    Yamamoto, S.5    Matsumoto, K.6
  • 45
    • 33749316457 scopus 로고    scopus 로고
    • Transient permeabilization of cell membranes by ultra- sound-exposed microbubbles is related to formation of hydrogen peroxide
    • Juffermans, L.J.; Dijkmans, P.A.; Musters, R.J.; Visser, C.A.; Kamp, O. Transient permeabilization of cell membranes by ultra- sound-exposed microbubbles is related to formation of hydrogen peroxide. Am. J. Physiol. Heart Circ. Physiol., 2006, 291, H1595-1601.
    • (2006) Am. J. Physiol. Heart Circ. Physiol , vol.291
    • Juffermans, L.J.1    Dijkmans, P.A.2    Musters, R.J.3    Visser, C.A.4    Kamp, O.5
  • 46
    • 0037332465 scopus 로고    scopus 로고
    • Transfection of NFkappaB-decoy oligodeoxynucleotides using efficient ultrasound-mediated gene transfer into donor kidneys prolonged survival of rat renal allografts
    • Azuma, H.; Tomita, N.; Kaneda, Y.; Koike, H.; Ogihara, T.; Katsuoka, Y. Transfection of NFkappaB-decoy oligodeoxynucleotides using efficient ultrasound-mediated gene transfer into donor kidneys prolonged survival of rat renal allografts. Gene Ther., 2003, 10, 415-425.
    • (2003) Gene Ther , vol.10 , pp. 415-425
    • Azuma, H.1    Tomita, N.2    Kaneda, Y.3    Koike, H.4    Ogihara, T.5    Katsuoka, Y.6
  • 47
    • 39649089582 scopus 로고    scopus 로고
    • Marked regression of liver metastasis by combined therapy of ultrasound-mediated NF kappaB-decoy transfer and transportal injection of paclitaxel, in mouse
    • Azuma, H.; Tomita, N.; Sakamoto, T.; Kiyama, S.; Inamoto, T.; Takahara, K. Marked regression of liver metastasis by combined therapy of ultrasound-mediated NF kappaB-decoy transfer and transportal injection of paclitaxel, in mouse. Int. J. Cancer, 2008, 122, 1645-1656.
    • (2008) Int. J. Cancer , vol.122 , pp. 1645-1656
    • Azuma, H.1    Tomita, N.2    Sakamoto, T.3    Kiyama, S.4    Inamoto, T.5    Takahara, K.6
  • 48
    • 43049183518 scopus 로고    scopus 로고
    • Alleviation of Abeta-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse model
    • Takeuchi, D., Sato, N.; Shimamura, M.; Kurinami, H.; Takeda, S.; Shinohara, M. Alleviation of Abeta-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse model. Gene Ther., 2008, 15, 561-571.
    • (2008) Gene Ther , vol.15 , pp. 561-571
    • Takeuchi, D.1    Sato, N.2    Shimamura, M.3    Kurinami, H.4    Takeda, S.5    Shinohara, M.6
  • 49
    • 0032543118 scopus 로고    scopus 로고
    • Adenoviral gene transfer to spinal-cord neurons: Intrathecal vs. intraparenchymal administration
    • Mannes, A.J.; Caudle, R.M.; O'Connell, B.C.; Iadarola, M.J. Adenoviral gene transfer to spinal-cord neurons: intrathecal vs. intraparenchymal administration. Brain Res., 1998, 793, 1-6.
    • (1998) Brain Res , vol.793 , pp. 1-6
    • Mannes, A.J.1    Caudle, R.M.2    O'Connell, B.C.3    Iadarola, M.J.4
  • 50
    • 0038826285 scopus 로고    scopus 로고
    • Optimization of ultrasound parameters for cardiac gene delivery of adenoviral or plasmid deoxyribonucleic acid by ultrasoundtargeted microbubble destruction
    • Chen, S.; Shohet, R.V.; Bekeredjian, R.; Frenkel, P.; Grayburn, P.A. Optimization of ultrasound parameters for cardiac gene delivery of adenoviral or plasmid deoxyribonucleic acid by ultrasoundtargeted microbubble destruction. J. Am. Coll. Cardiol., 2003, 42, 301-308.
    • (2003) J. Am. Coll. Cardiol , vol.42 , pp. 301-308
    • Chen, S.1    Shohet, R.V.2    Bekeredjian, R.3    Frenkel, P.4    Grayburn, P.A.5
  • 51
    • 67349230291 scopus 로고    scopus 로고
    • Microbubble stability is a major determinant of the efficiency of ultrasound and microbubble mediated in vivo gene transfer
    • Alter, J.; Sennoga, C.A.; Lopes, D.M.; Eckersley, R.J.; Wells, D.J. Microbubble stability is a major determinant of the efficiency of ultrasound and microbubble mediated in vivo gene transfer. Ultrasound Med. Biol., 2009, 35, 976-984.
    • (2009) Ultrasound Med. Biol , vol.35 , pp. 976-984
    • Alter, J.1    Sennoga, C.A.2    Lopes, D.M.3    Eckersley, R.J.4    Wells, D.J.5
  • 52
    • 0037464419 scopus 로고    scopus 로고
    • Intradermal immunization with novel plasmid DNA-coated nanoparticles via a needle-free injection device
    • Cui, Z.; Baizer, L.; Mumper, R.J. Intradermal immunization with novel plasmid DNA-coated nanoparticles via a needle-free injection device. J. Biotechnol., 2003, 102, 105-115.
    • (2003) J. Biotechnol , vol.102 , pp. 105-115
    • Cui, Z.1    Baizer, L.2    Mumper, R.J.3
  • 53
    • 33745646496 scopus 로고    scopus 로고
    • Current status and future prospects of needle-free liquid jet injectors
    • Mitragotri, S. Current status and future prospects of needle-free liquid jet injectors. Nat. Rev. Drug Discov., 2006, 5, 543-548.
    • (2006) Nat. Rev. Drug Discov , vol.5 , pp. 543-548
    • Mitragotri, S.1
  • 54
    • 33947594713 scopus 로고    scopus 로고
    • Protection of mice against rotavirus challenge following intradermal DNA immunization by Biojector needle-free injection
    • Choi, A.H.; Smiley, K.; Basu, M.; McNeal, M.M.; Shao, M.; Bean, J.A. Protection of mice against rotavirus challenge following intradermal DNA immunization by Biojector needle-free injection. Vaccine, 2007, 25, 3215-3218.
    • (2007) Vaccine , vol.25 , pp. 3215-3218
    • Choi, A.H.1    Smiley, K.2    Basu, M.3    McNeal, M.M.4    Shao, M.5    Bean, J.A.6
  • 55
    • 34250721613 scopus 로고    scopus 로고
    • Pre-clinical evaluation of a CEA DNA prime/protein boost vaccination strategy against colorectal cancer
    • Hallermalm, K.; Johansson, S.; Brave, A.; Ek, M.; Engstrom, G.; Boberg, A. Pre-clinical evaluation of a CEA DNA prime/protein boost vaccination strategy against colorectal cancer. Scand. J. Immunol., 2007, 66, 43-51.
    • (2007) Scand. J. Immunol , vol.66 , pp. 43-51
    • Hallermalm, K.1    Johansson, S.2    Brave, A.3    Ek, M.4    Engstrom, G.5    Boberg, A.6
  • 57
    • 0032008094 scopus 로고    scopus 로고
    • Intradermal DNA immunization of mice against influenza A virus using the novel PowderJect system
    • Degano, P.; Sarphie, D.F.; Bangham, C.R. Intradermal DNA immunization of mice against influenza A virus using the novel PowderJect system. Vaccine, 1998, 16, 394-398.
    • (1998) Vaccine , vol.16 , pp. 394-398
    • Degano, P.1    Sarphie, D.F.2    Bangham, C.R.3
  • 58
    • 0033575486 scopus 로고    scopus 로고
    • Phase 1 safety and immune response studies of a DNA vaccine encoding hepatitis B surface antigen delivered by a gene delivery device
    • Tacket, C.O.; Roy, M.J.; Widera, G.; Swain, W.F.; Broome, S.; Edelman, R. Phase 1 safety and immune response studies of a DNA vaccine encoding hepatitis B surface antigen delivered by a gene delivery device. Vaccine, 1999, 17, 2826-2829.
    • (1999) Vaccine , vol.17 , pp. 2826-2829
    • Tacket, C.O.1    Roy, M.J.2    Widera, G.3    Swain, W.F.4    Broome, S.5    Edelman, R.6
  • 59
    • 1542298891 scopus 로고    scopus 로고
    • Use of recombinant modified vaccinia Ankara viral vectors for equine influenza vaccination
    • Breathnach, C.C.; Rudersdorf, R.; Lunn, D.P. Use of recombinant modified vaccinia Ankara viral vectors for equine influenza vaccination. Vet. Immunol. Immunopathol., 2004, 98, 127-136.
    • (2004) Vet. Immunol. Immunopathol , vol.98 , pp. 127-136
    • Breathnach, C.C.1    Rudersdorf, R.2    Lunn, D.P.3
  • 60
    • 33746169418 scopus 로고    scopus 로고
    • Acceleration of wound healing by combined gene transfer of hepatocyte growth factor and prostacyclin synthase with Shima Jet
    • Kunugiza, Y.; Tomita, N.; Taniyama, Y.; Tomita, T.; Osako, M.K.; Tamai, K. Acceleration of wound healing by combined gene transfer of hepatocyte growth factor and prostacyclin synthase with Shima Jet. Gene Ther., 2006; 13, 1143-1152.
    • (2006) Gene Ther , vol.13 , pp. 1143-1152
    • Kunugiza, Y.1    Tomita, N.2    Taniyama, Y.3    Tomita, T.4    Osako, M.K.5    Tamai, K.6
  • 61
    • 0032851810 scopus 로고    scopus 로고
    • In vivo gene introduction into keratinocytes using jet injection
    • Sawamura, D.; Ina, S.; Itai, K.; Meng, X.; Kon, A.; Tamai, K. In vivo gene introduction into keratinocytes using jet injection. Gene Ther., 1999, 6, 1785-1787.
    • (1999) Gene Ther , vol.6 , pp. 1785-1787
    • Sawamura, D.1    Ina, S.2    Itai, K.3    Meng, X.4    Kon, A.5    Tamai, K.6
  • 62
    • 37349096386 scopus 로고    scopus 로고
    • Improvement of survival of skin flaps by combined gene transfer of hepatocyte growth factor and prostacyclin synthase
    • Nakagawa, A.; Makino, H.; Aoki, M.; Miyake, T.; Shiraya, S.; Nakamura, T. Improvement of survival of skin flaps by combined gene transfer of hepatocyte growth factor and prostacyclin synthase. J. Gene Med., 2007, 9, 1087-1094.
    • (2007) J. Gene Med , vol.9 , pp. 1087-1094
    • Nakagawa, A.1    Makino, H.2    Aoki, M.3    Miyake, T.4    Shiraya, S.5    Nakamura, T.6
  • 63
    • 0035117313 scopus 로고    scopus 로고
    • Nonviral in vivo gene delivery into tumors using a novel low volume jet-injection technology
    • Walther, W.; Stein, U.; Fichtner, I.; Malcherek, L.; Lemm, M.; Schlag, P.M. Nonviral in vivo gene delivery into tumors using a novel low volume jet-injection technology. Gene Ther., 2001, 8, 173-180.
    • (2001) Gene Ther , vol.8 , pp. 173-180
    • Walther, W.1    Stein, U.2    Fichtner, I.3    Malcherek, L.4    Lemm, M.5    Schlag, P.M.6
  • 64
    • 21644490243 scopus 로고    scopus 로고
    • Low-volume jet injection for efficient nonviral in vivo gene transfer
    • Walther, W.; Stein, U.; Fichtner, I.; Schlag, P.M. Low-volume jet injection for efficient nonviral in vivo gene transfer. Mol. Biotechnol., 2004, 28, 121-128.
    • (2004) Mol. Biotechnol , vol.28 , pp. 121-128
    • Walther, W.1    Stein, U.2    Fichtner, I.3    Schlag, P.M.4
  • 65
    • 58149337433 scopus 로고    scopus 로고
    • Novel jet-injection technology for nonviral intratumoral gene transfer in patients with melanoma and breast cancer
    • Walther, W.; Siegel, R.; Kobelt, D.; Knosel, T.; Dietel, M.; Bembenek, A. Novel jet-injection technology for nonviral intratumoral gene transfer in patients with melanoma and breast cancer. Clin. Cancer Res., 2008, 14, 7545-7553.
    • (2008) Clin. Cancer Res , vol.14 , pp. 7545-7553
    • Walther, W.1    Siegel, R.2    Kobelt, D.3    Knosel, T.4    Dietel, M.5    Bembenek, A.6
  • 67
    • 0028819916 scopus 로고
    • Gene gun-based nucleic acid immunization: Elicitation of humoral and cytotoxic T lymphocyte responses following epidermal delivery of nanogram quantities of DNA
    • Pertmer, T.M.; Eisenbraun, M.D.; McCabe, D.; Prayaga, S.K.; Fuller, D.H.; Haynes, J.R. Gene gun-based nucleic acid immunization: elicitation of humoral and cytotoxic T lymphocyte responses following epidermal delivery of nanogram quantities of DNA. Vaccine, 1995, 13, 1427-1430.
    • (1995) Vaccine , vol.13 , pp. 1427-1430
    • Pertmer, T.M.1    Eisenbraun, M.D.2    McCabe, D.3    Prayaga, S.K.4    Fuller, D.H.5    Haynes, J.R.6
  • 68
    • 52449104809 scopus 로고    scopus 로고
    • DNA vaccines: Ready for prime time?
    • Kutzler, M.A.; Weiner, D.B. DNA vaccines: ready for prime time? Nat. Rev. Genet., 2008, 9, 776-788.
    • (2008) Nat. Rev. Genet , vol.9 , pp. 776-788
    • Kutzler, M.A.1    Weiner, D.B.2
  • 69
    • 0028081659 scopus 로고
    • Direct gene transfer in skeletal muscle: Plasmid DNA-based immunization against the hepatitis B virus surface antigen
    • Davis, H.L.; Michel, M.L.; Mancini, M.; Schleef, M.; Whalen, R.G. Direct gene transfer in skeletal muscle: plasmid DNA-based immunization against the hepatitis B virus surface antigen. Vaccine, 1994, 12, 1503-1509.
    • (1994) Vaccine , vol.12 , pp. 1503-1509
    • Davis, H.L.1    Michel, M.L.2    Mancini, M.3    Schleef, M.4    Whalen, R.G.5
  • 70
    • 34548070699 scopus 로고    scopus 로고
    • A new multi-clade DNA prime/ recombinant MVA boost vaccine induces broad and high levels of HIV-1specific CD8(+) T-cell and humoral responses in mice
    • Brave, A.; Boberg, A.; Gudmundsdotter, L.; Rollman, E.; Hallermalm, K.; Ljungberg, K. A new multi-clade DNA prime/ recombinant MVA boost vaccine induces broad and high levels of HIV-1specific CD8(+) T-cell and humoral responses in mice. Mol. Ther., 2007, 15, 1724-1733.
    • (2007) Mol. Ther , vol.15 , pp. 1724-1733
    • Brave, A.1    Boberg, A.2    Gudmundsdotter, L.3    Rollman, E.4    Hallermalm, K.5    Ljungberg, K.6
  • 71
    • 55849093906 scopus 로고    scopus 로고
    • Phase I study of a herpes simplex virus type 2 (HSV2) DNA vaccine administered to healthy, HSV-2-seronegative adults by a needle-free injection system
    • Cattamanchi, A.; Posavad, C.M.; Wald, A.; Baine, Y.; Moses, J.; Higgins, T.J. Phase I study of a herpes simplex virus type 2 (HSV2) DNA vaccine administered to healthy, HSV-2-seronegative adults by a needle-free injection system. Clin. Vaccine Immunol., 2008, 15, 1638-1643.
    • (2008) Clin. Vaccine Immunol , vol.15 , pp. 1638-1643
    • Cattamanchi, A.1    Posavad, C.M.2    Wald, A.3    Baine, Y.4    Moses, J.5    Higgins, T.J.6
  • 73
    • 28444497720 scopus 로고    scopus 로고
    • Multigene/multisubtype HIV-1 vaccine induces potent cellular and humoral immune responses by needle-free intradermal delivery
    • Brave, A.; Ljungberg, K.; Boberg, A.; Rollman, E.; Isaguliants, M.; Lundgren, B. Multigene/multisubtype HIV-1 vaccine induces potent cellular and humoral immune responses by needle-free intradermal delivery. Mol. Ther., 2005, 12, 1197-1205.
    • (2005) Mol. Ther , vol.12 , pp. 1197-1205
    • Brave, A.1    Ljungberg, K.2    Boberg, A.3    Rollman, E.4    Isaguliants, M.5    Lundgren, B.6
  • 74
    • 0037393454 scopus 로고    scopus 로고
    • Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: A case report
    • Nicoll, J.A.; Wilkinson, D.; Holmes, C.; Steart, P.; Markham, H.; Weller, R.O. Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report. Nat. Med., 2003, 9, 448-452.
    • (2003) Nat. Med , vol.9 , pp. 448-452
    • Nicoll, J.A.1    Wilkinson, D.2    Holmes, C.3    Steart, P.4    Markham, H.5    Weller, R.O.6
  • 75
    • 0041886776 scopus 로고    scopus 로고
    • Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease
    • Monsonego, A.; Zota, V.; Karni, A.; Krieger, J.I.; Bar-Or, A.; Bitan, G. Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease. J. Clin. Invest., 2003, 112, 415-422.
    • (2003) J. Clin. Invest , vol.112 , pp. 415-422
    • Monsonego, A.1    Zota, V.2    Karni, A.3    Krieger, J.I.4    Bar-Or, A.5    Bitan, G.6
  • 76
    • 70350735909 scopus 로고    scopus 로고
    • DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model
    • Lambracht-Washington, D.; Qu, B.X.; Fu, M.; Eagar, T.N.; Stuve, O.; Rosenberg, R.N. DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model. JAMA, 2009, 302, 1796-802.
    • (2009) JAMA , vol.302 , pp. 1796-1802
    • Lambracht-Washington, D.1    Qu, B.X.2    Fu, M.3    Eagar, T.N.4    Stuve, O.5    Rosenberg, R.N.6
  • 78
    • 0034332960 scopus 로고    scopus 로고
    • Naked DNA vaccination differentially modulates autoimmune responses in experimental autoimmune encephalomyelitis
    • Selmaj, K.; Kowal, C.; Walczak, A.; Nowicka, J.; Raine, C.S. Naked DNA vaccination differentially modulates autoimmune responses in experimental autoimmune encephalomyelitis. J. Neuroimmunol., 2000, 111, 34-44.
    • (2000) J. Neuroimmunol , vol.111 , pp. 34-44
    • Selmaj, K.1    Kowal, C.2    Walczak, A.3    Nowicka, J.4    Raine, C.S.5
  • 79
    • 2642588817 scopus 로고    scopus 로고
    • Differential prevention of experimental autoimmune encephalomyelitis with antigen-specific DNA vaccination
    • Walczak, A.; Szymanska, B.; Selmaj, K. Differential prevention of experimental autoimmune encephalomyelitis with antigen-specific DNA vaccination. Clin. Neurol. Neurosurg., 2004, 106, 241-245.
    • (2004) Clin. Neurol. Neurosurg , vol.106 , pp. 241-245
    • Walczak, A.1    Szymanska, B.2    Selmaj, K.3
  • 80
    • 34848865834 scopus 로고    scopus 로고
    • Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial
    • Bar-Or, A.; Vollmer, T.; Antel, J.; Arnold, D.L.; Bodner, C.A.; Campagnolo, D. Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial. Arch. Neurol., 2007, 64, 1407-1415.
    • (2007) Arch. Neurol , vol.64 , pp. 1407-1415
    • Bar-Or, A.1    Vollmer, T.2    Antel, J.3    Arnold, D.L.4    Bodner, C.A.5    Campagnolo, D.6
  • 81
    • 44849103664 scopus 로고    scopus 로고
    • Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis
    • Garren, H.; Robinson, W.H.; Krasulova, E.; Havrdova, E.; Nadj, C.; Selmaj, K. Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis. Ann. Neurol., 2008, 63, 611-620.
    • (2008) Ann. Neurol , vol.63 , pp. 611-620
    • Garren, H.1    Robinson, W.H.2    Krasulova, E.3    Havrdova, E.4    Nadj, C.5    Selmaj, K.6
  • 83
    • 13644249272 scopus 로고    scopus 로고
    • Organ-specific expression of the lacZ gene controlled by the opsin promoter after intravenous gene administration in adult mice
    • Zhu, C.; Zhang, Y.; Zhang, Y.F.; Yi Li, J.; Boado, R.J.; Pardridge, W.M. Organ-specific expression of the lacZ gene controlled by the opsin promoter after intravenous gene administration in adult mice. J. Gene Med., 2004, 6, 906-912.
    • (2004) J. Gene Med , vol.6 , pp. 906-912
    • Zhu, C.1    Zhang, Y.2    Zhang, Y.F.3    Yi, L.J.4    Boado, R.J.5    Pardridge, W.M.6


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