In vivo gene introduction into keratinocytes using jet injection

Gene Therapy

Volumn 6, Issue 10, 1999, Pages 1785-1787

  Sawamura, D ^a   Ina, S ^a   Itai, K ^a   Meng, X ^a   Kon, A ^a   Tamai, K ^a   Hanada, K ^a   Hashimoto, I ^a  

^a HIROSAKI UNIVERSITY   (Japan)

Author keywords

Epidermis; Gene transfer; Jet injection; Keratinocyte gene therapy

Indexed keywords

BETA GALACTOSIDASE; DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; EPIDERMIS; EXPRESSION VECTOR; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; JET INJECTION; KERATINOCYTE; NEEDLE; NONHUMAN; PLASMID; PRIORITY JOURNAL; RAT; SKIN; SKIN TRANSPLANTATION;

ANIMALS; BETA-GALACTOSIDASE; BIOLISTICS; DNA; GENE EXPRESSION; GENE THERAPY; HUMANS; INJECTIONS; INJECTIONS, JET; KERATINOCYTES; RATS; RATS, NUDE; SKIN DISEASES; SKIN TRANSPLANTATION; TRANSPLANTATION, HETEROLOGOUS;

EID: 0032851810     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301002     Document Type: Article

References (17)

1. Greenhalgh DA, Rothnagel JA, Roop DR. Epidermis: an attractive target tissue for gene therapy. J Invest Dermatol 1992; 103: 63S-69S.
2. Meng X et al. Keratinocyte gene therapy for systemic diseases: circulating interleukin-10 released from gene-transferred keratinocytes inhibited contact hypersensitivity at distant areas of the skin. J Clin Invest 1998; 101: 1462-1467.
3. Cheng L, Ziegelhoffer PR, Yang NS. In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by particle bombardment. Proc Natl Acad Sci USA 1993; 90: 4455-4459.
4. Setoguchi Y, Jaffe HA, Dane C, Crystal RG. Ex vivo and in vivo gene transfer to the skin using replication-deficient recombinant adenovirus vectors. J Invest Dermatol 1994; 102: 415-421.
5. Hengge UR et al. Cytokine gene expression in epidermis with biological effects following injection of naked DNA. Nat Genet 1995; 10: 161-166.
6. Sawamura D et al. In vivo gene transfer of a foreign gene to keratinocyte using the hemagglutinating virus of the Japan-liposome method. J Invest Dermatol 1997; 108: 195-199.
7. Lu B et al. Topical application of viral vectors for epidermal gene transfer. J Invest Dermatol 1997; 108: 803-808.
8. Li L, Huffman RM. The feasibility of targeted selective gene therapy of the hair follicle. Nature Med 1995; 1: 705-706.
9. Furth PA, Shamay A, Wall RJ, Hennighausen L. Gene transfer into somatic tissues by jet injection. Anal Biochem 1992; 205: 365-368.
10. Brandsma J, Yang ZH, Barthold SW, Johnson EA. Use of a rapid, efficient inoculation method to induce papillomas by cottontail rabbit papillomavirus DNA shows that the E7 gene is required. Proc Natl Acad Sci USA 1991; 88: 4816-4820.
11. Soyka P, Zellweger GA. Betamethasome in the treatment of hypertrophic scars. Helv Chir Acta 1980; 47: 137-140.
12. Sparrow G, Abell E. Granuloma annulare and necrobiosis lipoidica treated by jet injection. Br J Dermatol 1975; 93: 85-89.
13. Niwa H, Yamamura K, Miyazaki J. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 1991; 108: 193-200.
14. Sawamura D et al. Induction of keratinocyte proliferation and lymphocytic infiltration by in vivo introduction of the IL-6 gene into keratinocytes and possibility of keratinocyte gene therapy for inflammatory skin diseases using IL-6 mutant genes. J Immunol 1998; 161: 5633-5639.
15. Sawamura D et al. Promoter/enhancer cassettes for keratinocyte gene therapy. J Invest Dermatol 1999; 112: 829-830.
16. Furth PA, Shamay A, Hennighausen L. Gene transfer into mammalian cells by jet injection. Hybridoma 1995; 14: 149-152.
17. Hengge UR, Walker PS, Vogel JC. Expression of naked DNA in human, pig, and mouse skin. J Clin Invest 1996; 97: 2911-2916.