-
1
-
-
0034516988
-
Toward a comprehensive theory for Alzheimer's disease: Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid β-protein
-
Selkoe DJ. Toward a comprehensive theory for Alzheimer's disease: hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid β-protein. Ann N Y Acad Sci. 2000;924:17-25.
-
(2000)
Ann N Y Acad Sci
, vol.924
, pp. 17-25
-
-
Selkoe, D.J.1
-
2
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe DJ. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev. 2001;81:741-766.
-
(2001)
Physiol Rev
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
3
-
-
0031052381
-
Amyloid, the preseniline and Alzheimer's disease
-
Hardy J. Amyloid, the preseniline and Alzheimer's disease. Trends Neurosci. 1997;20:154-159.
-
(1997)
Trends Neurosci
, vol.20
, pp. 154-159
-
-
Hardy, J.1
-
4
-
-
0033600274
-
Translating cell biology into therapeutic advances in Alzheimer's disease
-
Selkoe DJ. Translating cell biology into therapeutic advances in Alzheimer's disease. Nature. 1999;399(6738 suppl):A23-A31.
-
(1999)
Nature
, vol.399
, Issue.6738 SUPPL.
-
-
Selkoe, D.J.1
-
5
-
-
0242268945
-
Immunotherapeutic approaches to Alzheimer's disease
-
Monsonego A, Weiner HL. Immunotherapeutic approaches to Alzheimer's disease. Science. 2003;302:834-838.
-
(2003)
Science
, vol.302
, pp. 834-838
-
-
Monsonego, A.1
Weiner, H.L.2
-
7
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk D, Barbour R, Dunn W, et al. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature. 1999;400:173-177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
-
8
-
-
0036703483
-
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
-
Kotilinek LA, Bacskai B, Westerman M, et al. Reversible memory loss in a mouse transgenic model of Alzheimer's disease. J Neurosci. 2002;22:6331-6335.
-
(2002)
J Neurosci
, vol.22
, pp. 6331-6335
-
-
Kotilinek, L.A.1
Bacskai, B.2
Westerman, M.3
-
9
-
-
0033835996
-
Peripherally administered antibodies against amyloid-beta peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
Bard F, Cannon C, Barbour R, et al. Peripherally administered antibodies against amyloid-beta peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat Med. 2000;6:916-919.
-
(2000)
Nat Med
, vol.6
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
-
10
-
-
0036853548
-
Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer's disease
-
Hock C, Konietzko U, Papassotiropoulos A, et al. Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer's disease. Nat Med. 2002;8:1270-1275.
-
(2002)
Nat Med
, vol.8
, pp. 1270-1275
-
-
Hock, C.1
Konietzko, U.2
Papassotiropoulos, A.3
-
11
-
-
0038100154
-
Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease
-
Hock C, Konietzko U, Streffer JR, et al. Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease. Neuron. 2003;38:547-554.
-
(2003)
Neuron
, vol.38
, pp. 547-554
-
-
Hock, C.1
Konietzko, U.2
Streffer, J.R.3
-
12
-
-
10044288452
-
Genetic Immunization approach for therapy of Alzheimer disease
-
Qu B, Rosenberg RW, Johnston SA. Genetic Immunization approach for therapy of Alzheimer disease [abstract]. Neurobiol Aging. 2004;25(suppl):S568- S569.
-
(2004)
Neurobiol Aging
, vol.25
, Issue.SUPPL.
-
-
Qu, B.1
Rosenberg, R.W.2
Johnston, S.A.3
-
13
-
-
0041859398
-
High-level generation of polyclonal antibodies by genetic immunization
-
Chambers RS, Johnston SA. High-level generation of polyclonal antibodies by genetic immunization. Nat Biotechnol. 2003;21:1088-1092.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 1088-1092
-
-
Chambers, R.S.1
Johnston, S.A.2
-
14
-
-
2342663201
-
DMA vaccine encoding human immunodeficiency virus-1 Gag, targeted to the major histocompatibility complex II compartment by lysosomal-associated membrane protein, elicits enhanced long-term memory response
-
de Arruda LB, Chikhlikar PR, August JT, Marques ET. DMA vaccine encoding human immunodeficiency virus-1 Gag, targeted to the major histocompatibility complex II compartment by lysosomal-associated membrane protein, elicits enhanced long-term memory response. Immunology. 2004;112:126-133.
-
(2004)
Immunology
, vol.112
, pp. 126-133
-
-
De Arruda, L.B.1
Chikhlikar, P.R.2
August, J.T.3
Marques, E.T.4
-
15
-
-
0026579897
-
Genetic immunization is a simple method for eliciting an immune response
-
Tang DC, DeVit M, Johnston SA. Genetic immunization is a simple method for eliciting an immune response. Nature. 1992;356:152-154.
-
(1992)
Nature
, vol.356
, pp. 152-154
-
-
Tang, D.C.1
DeVit, M.2
Johnston, S.A.3
-
16
-
-
0035164034
-
ELISPOT assay for detection of peptide specific interferon-gamma secreting cells in rhesus macaques
-
Kumar A, Weiss W, Tine JA, Hoffman SL, Rogers WO. ELISPOT assay for detection of peptide specific interferon-gamma secreting cells in rhesus macaques. J Immunol Methods. 2001;247:49-60.
-
(2001)
J Immunol Methods
, vol.247
, pp. 49-60
-
-
Kumar, A.1
Weiss, W.2
Tine, J.A.3
Hoffman, S.L.4
Rogers, W.O.5
-
17
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt DR, Ratovitski T, van Lare J, et al. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron. 1997;19:939-945.
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
-
18
-
-
10744233138
-
Genetic background regulates β-amyloid precursor protein processing and β-amyloid deposition in the mouse
-
Lehman EJ, Kulnane LS, Gao Y, et al. Genetic background regulates β-amyloid precursor protein processing and β-amyloid deposition in the mouse. Hum Mol Genet. 2003;12:2949-2956.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2949-2956
-
-
Lehman, E.J.1
Kulnane, L.S.2
Gao, Y.3
-
19
-
-
0032845737
-
Decrease of glial fibrillary acidic protein in rat frontal cortex following aluminum treatment
-
Guo-Ross SX, Yang EY, Walsh TJ, Bondy SC. Decrease of glial fibrillary acidic protein in rat frontal cortex following aluminum treatment. J Neurochem. 1999;73:1609-1614.
-
(1999)
J Neurochem
, vol.73
, pp. 1609-1614
-
-
Guo-Ross, S.X.1
Yang, E.Y.2
Walsh, T.J.3
Bondy, S.C.4
-
20
-
-
0028863527
-
Protection against mycoplasma infection using expression-library immunization
-
Barry MA, Lai WC, Johnston SA. Protection against mycoplasma infection using expression-library immunization. Nature. 1995;377:632-635.
-
(1995)
Nature
, vol.377
, pp. 632-635
-
-
Barry, M.A.1
Lai, W.C.2
Johnston, S.A.3
-
21
-
-
0027411456
-
Heterologous protection against influenza by injection of DNA encoding a viral protein
-
Ulmer JB, Donnelly JJ, Parker SE, et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science. 1993;259:1745-1749.
-
(1993)
Science
, vol.259
, pp. 1745-1749
-
-
Ulmer, J.B.1
Donnelly, J.J.2
Parker, S.E.3
-
22
-
-
0033589811
-
Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal compartment enhances the antitumor immunity of DNA vaccines against murine human papillomavirus type 16 E7-exprssing tumors
-
Ji H, Wang TL, Chen CH, et al. Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal compartment enhances the antitumor immunity of DNA vaccines against murine human papillomavirus type 16 E7-exprssing tumors. Hum Gene Ther. 1999;10:2727-2740.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 2727-2740
-
-
Ji, H.1
Wang, T.L.2
Chen, C.H.3
-
23
-
-
7944236860
-
Antibodies from a DNA peptide vaccination decrease the brain amyloid burden in a mouse model of Alzheimer's disease
-
Schultz JG, Salzer U, Mohajerl MH, et al. Antibodies from a DNA peptide vaccination decrease the brain amyloid burden in a mouse model of Alzheimer's disease. J Mol Med [online series]. Available at: http://www. 2004;0570-z.
-
(2004)
J Mol Med [Online Series]
-
-
Schultz, J.G.1
Salzer, U.2
Mohajerl, M.H.3
-
24
-
-
0031093543
-
Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization
-
Feltquate DM, Heaney S, Webster RG, Robinson HL. Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization. J Immunol. 1997;158:2278-2284.
-
(1997)
J Immunol
, vol.158
, pp. 2278-2284
-
-
Feltquate, D.M.1
Heaney, S.2
Webster, R.G.3
Robinson, H.L.4
-
25
-
-
0037135660
-
Gene gun bombardment with gold particles displays a particular Th2-promoting signal that over-rules the Th1-inducing effect of immunostimulatory CpG motifs in DNA
-
Weiss R, Scheiblhofer S, Freund J, et al. Gene gun bombardment with gold particles displays a particular Th2-promoting signal that over-rules the Th1-inducing effect of immunostimulatory CpG motifs in DNA. Vaccine. 2002;20:3148-3154.
-
(2002)
Vaccine
, vol.20
, pp. 3148-3154
-
-
Weiss, R.1
Scheiblhofer, S.2
Freund, J.3
-
26
-
-
10044232897
-
Alzheimer's disease and immunotherapy
-
Solomon B. Alzheimer's disease and immunotherapy. Curr Alzheimer Res. 2004;1:149-163.
-
(2004)
Curr Alzheimer Res
, vol.1
, pp. 149-163
-
-
Solomon, B.1
|