Allopregnanolone regulates neurogenesis and depressive/anxiety-like behaviour in a social isolation rodent model of chronic stress

Neuropharmacology

Volumn 63, Issue 8, 2012, Pages 1315-1326

  Evans, Jane ^a   Sun, Yuhui ^a   McGregor, Ailsa ^a   Connor, Bronwen ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Allopregnanolone; BDNF; Chronic stress; Corticosteroid; Depression anxiety; Neurogenesis

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; BRAIN DERIVED NEUROTROPHIC FACTOR; FLUOXETINE; PLACEBO;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY DISORDER; ARTICLE; BRAIN NERVE CELL; CELL SURVIVAL; CHRONIC STRESS; CONTROLLED STUDY; DEPRESSION; DRUG MECHANISM; FORCED SWIMMING TEST; HYPOPHYSIS ADRENAL SYSTEM; MALE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SOCIAL ISOLATION;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL SURVIVAL; CHRONIC DISEASE; DEPRESSION; DEXAMETHASONE; FEEDING BEHAVIOR; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MOTOR ACTIVITY; NEURAL STEM CELLS; NEUROGENESIS; PREGNANOLONE; RATS; RATS, WISTAR; SOCIAL ISOLATION; STRESS, PSYCHOLOGICAL; SWIMMING;

EID: 84867514676     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.08.012     Document Type: Article

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