메뉴 건너뛰기




Volumn 89, Issue 1, 2008, Pages 85-93

Differential effect of environment enrichment and social isolation on depressive-like behavior, spontaneous activity and serotonin and norepinephrine concentration in prefrontal cortex and ventral striatum

Author keywords

Brain development; Depression; Environmental enrichment; Forced swimming behavior; Model; Monoamines; Open field behavior; Prefrontal cortex; Rats; Social isolation; Stress; Striatum

Indexed keywords

NORADRENALIN; SEROTONIN;

EID: 38049113439     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2007.11.004     Document Type: Article
Times cited : (219)

References (50)
  • 1
    • 0019600598 scopus 로고
    • Social housing conditions influence escape deficits produced by uncontrollable stress: "Assessment of the contribution of norepinephrine"
    • Anisman H., and Sklar L.S. Social housing conditions influence escape deficits produced by uncontrollable stress: "Assessment of the contribution of norepinephrine". Behav Neural Biol 32 (1981) 406-427
    • (1981) Behav Neural Biol , vol.32 , pp. 406-427
    • Anisman, H.1    Sklar, L.S.2
  • 2
    • 0026513157 scopus 로고
    • Depression as a consequence of inadequate neurochemical adaptation in response to stressors
    • Anisman H., and Zacharko R.M. Depression as a consequence of inadequate neurochemical adaptation in response to stressors. Br J Psychiatry 160 (1992) 36-43
    • (1992) Br J Psychiatry , vol.160 , pp. 36-43
    • Anisman, H.1    Zacharko, R.M.2
  • 3
    • 0010554730 scopus 로고    scopus 로고
    • Long term behavioral and neurochemical changes after isolation rearing in rats
    • Bakshi V.P., Schwarzkopf S.B., Braff D.L., and Geyer M.A. Long term behavioral and neurochemical changes after isolation rearing in rats. Biol Psychiatry 39 (1996) 555
    • (1996) Biol Psychiatry , vol.39 , pp. 555
    • Bakshi, V.P.1    Schwarzkopf, S.B.2    Braff, D.L.3    Geyer, M.A.4
  • 4
    • 0027233562 scopus 로고
    • Social isolation attenuates rat forebrain 5-HT release induced by KCI stimulation and exposure to a novel environment
    • Bickerdike M.J., Wright I.K., and Marsden C.A. Social isolation attenuates rat forebrain 5-HT release induced by KCI stimulation and exposure to a novel environment. Behav Pharmacol 4 (1993) 231-236
    • (1993) Behav Pharmacol , vol.4 , pp. 231-236
    • Bickerdike, M.J.1    Wright, I.K.2    Marsden, C.A.3
  • 5
    • 33244467253 scopus 로고    scopus 로고
    • Factor analysis of forced swimming test, sucrose preference test and open field test on enriched, social and isolated reared rats
    • Brenes-Sáenz J.C., Rodríguez-Villagra O., and Fornaguera-Trías J. Factor analysis of forced swimming test, sucrose preference test and open field test on enriched, social and isolated reared rats. Behav Brain Res 169 (2006) 57-65
    • (2006) Behav Brain Res , vol.169 , pp. 57-65
    • Brenes-Sáenz, J.C.1    Rodríguez-Villagra, O.2    Fornaguera-Trías, J.3
  • 6
    • 0036570222 scopus 로고    scopus 로고
    • Assessing antidepressant activity in rodents: recent developments and future needs
    • Cryan J.F., Markou A., and Lucki I. Assessing antidepressant activity in rodents: recent developments and future needs. Trends Pharmacol Sci 23 (2002) 238-245
    • (2002) Trends Pharmacol Sci , vol.23 , pp. 238-245
    • Cryan, J.F.1    Markou, A.2    Lucki, I.3
  • 7
    • 3042710247 scopus 로고    scopus 로고
    • The neuroimaging studies of mood disorders
    • Charney D., and Nestler E. (Eds), Oxford University Press Inc, New York
    • Drevets W.C., Gadde K.M., and Krishnan K.R.R. The neuroimaging studies of mood disorders. In: Charney D., and Nestler E. (Eds). Neurobiology of Mental Illness (2004), Oxford University Press Inc, New York 461-490
    • (2004) Neurobiology of Mental Illness , pp. 461-490
    • Drevets, W.C.1    Gadde, K.M.2    Krishnan, K.R.R.3
  • 8
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • Duman R.S., and Montaggia L.M. A neurotrophic model for stress-related mood disorders. Biol Psychiatry 59 (2006) 1116-1127
    • (2006) Biol Psychiatry , vol.59 , pp. 1116-1127
    • Duman, R.S.1    Montaggia, L.M.2
  • 9
    • 27644580448 scopus 로고    scopus 로고
    • Effects of social and physical enrichment on open field activity differ in male and female Sprague-Dawley rats
    • Elliot B., and Grunberg N. Effects of social and physical enrichment on open field activity differ in male and female Sprague-Dawley rats. Behav Brain Res 165 (2005) 187-196
    • (2005) Behav Brain Res , vol.165 , pp. 187-196
    • Elliot, B.1    Grunberg, N.2
  • 10
    • 0035985577 scopus 로고    scopus 로고
    • Early-life handling stimulation and environmental enrichment. Are some of their effects mediated by similar neural mechanisms?
    • Fernández-Teruel A., Giménez-Lort L., Escorihuela R.M., Gil L., Aguilar R., Thierry S., et al. Early-life handling stimulation and environmental enrichment. Are some of their effects mediated by similar neural mechanisms?. Pharmacol Biochem Behav 73 (2002) 233-245
    • (2002) Pharmacol Biochem Behav , vol.73 , pp. 233-245
    • Fernández-Teruel, A.1    Giménez-Lort, L.2    Escorihuela, R.M.3    Gil, L.4    Aguilar, R.5    Thierry, S.6
  • 11
    • 0036211883 scopus 로고    scopus 로고
    • Time course of deficits in open field behavior after unilateral neostriatal 6-hydroxydopamine lesions
    • Fornaguera J., and Schwarting R.K.W. Time course of deficits in open field behavior after unilateral neostriatal 6-hydroxydopamine lesions. Neurotox Res 4 (2002) 41-49
    • (2002) Neurotox Res , vol.4 , pp. 41-49
    • Fornaguera, J.1    Schwarting, R.K.W.2
  • 12
    • 0031026322 scopus 로고    scopus 로고
    • Social isolation in the rat enhances α-2 autoreceptor function in the hippocampus in vivo
    • Fulford A.J., and Marsden C.A. Social isolation in the rat enhances α-2 autoreceptor function in the hippocampus in vivo. Neuroscience 77 (1997) 57-64
    • (1997) Neuroscience , vol.77 , pp. 57-64
    • Fulford, A.J.1    Marsden, C.A.2
  • 13
    • 26944463057 scopus 로고    scopus 로고
    • Novel stressors affected catecholamine stores in socially isolated normotensive and spontaneously hypertensive rats
    • Gavrilovic L., Spasojevic N., and Dronjak S. Novel stressors affected catecholamine stores in socially isolated normotensive and spontaneously hypertensive rats. Auton Neurosci Basic Clin 122 (2005) 38-44
    • (2005) Auton Neurosci Basic Clin , vol.122 , pp. 38-44
    • Gavrilovic, L.1    Spasojevic, N.2    Dronjak, S.3
  • 14
    • 0031979135 scopus 로고    scopus 로고
    • Social deprivation of neonatal, adolescent, and adult rats has distinct neurochemical and behavioural consequences
    • Hall F.S. Social deprivation of neonatal, adolescent, and adult rats has distinct neurochemical and behavioural consequences. Crit Rev Neurobiol 12 (1998) 129-162
    • (1998) Crit Rev Neurobiol , vol.12 , pp. 129-162
    • Hall, F.S.1
  • 15
    • 0032583785 scopus 로고    scopus 로고
    • The effects of social isolation on the forced swimming test in Fawn Hooded and Wistar rats
    • Hall F.S., Huang S., Fong C.F., and Pert A. The effects of social isolation on the forced swimming test in Fawn Hooded and Wistar rats. J Neurosci Methods 78 (1998) 47-51
    • (1998) J Neurosci Methods , vol.78 , pp. 47-51
    • Hall, F.S.1    Huang, S.2    Fong, C.F.3    Pert, A.4
  • 16
    • 0034865015 scopus 로고    scopus 로고
    • Enhanced corticosterone release after a modified forced swim test in Fawn Hooded rats is independent of rearing experience
    • Hall F.S., Sundstrom J.M., Lerner J., and Pert A. Enhanced corticosterone release after a modified forced swim test in Fawn Hooded rats is independent of rearing experience. Pharmacol Biochem Behav 69 (2001) 629-634
    • (2001) Pharmacol Biochem Behav , vol.69 , pp. 629-634
    • Hall, F.S.1    Sundstrom, J.M.2    Lerner, J.3    Pert, A.4
  • 17
    • 34247513400 scopus 로고    scopus 로고
    • Enriched environments influence depression-related behavior in adult mice and the survival of newborn cells in their hippocampi
    • Hattori S., Hashimoto R., Miyakawa T., Yamanaka H., Maeno H., Wada K., et al. Enriched environments influence depression-related behavior in adult mice and the survival of newborn cells in their hippocampi. Behav Brain Res 180 (2007) 69-76
    • (2007) Behav Brain Res , vol.180 , pp. 69-76
    • Hattori, S.1    Hashimoto, R.2    Miyakawa, T.3    Yamanaka, H.4    Maeno, H.5    Wada, K.6
  • 18
    • 26044443198 scopus 로고    scopus 로고
    • The pathogenesis of clinical depression: stressor-and cytokine-induced alterations of neuroplasticity
    • Hayley S., Poulter M.O., Merali Z., and Anisman H. The pathogenesis of clinical depression: stressor-and cytokine-induced alterations of neuroplasticity. Neuroscience 135 (2005) 659-678
    • (2005) Neuroscience , vol.135 , pp. 659-678
    • Hayley, S.1    Poulter, M.O.2    Merali, Z.3    Anisman, H.4
  • 19
    • 0034638494 scopus 로고    scopus 로고
    • Behavioral, neurochemical and endocrinological characterization of the early isolation syndrome
    • Heidbreder C.A., Weiss I.C., Domeney A.M., Pryce C., Homberg J., and Hedou G. Behavioral, neurochemical and endocrinological characterization of the early isolation syndrome. Neuroscience 100 (2000) 749-768
    • (2000) Neuroscience , vol.100 , pp. 749-768
    • Heidbreder, C.A.1    Weiss, I.C.2    Domeney, A.M.3    Pryce, C.4    Homberg, J.5    Hedou, G.6
  • 20
    • 0025065081 scopus 로고
    • Effects of social isolation on brain catecholamines and forced swimming in rats: prevention by antidepressant treatment
    • Heritch A.J., Henderson K., and Westfall T.C. Effects of social isolation on brain catecholamines and forced swimming in rats: prevention by antidepressant treatment. J Psychother Pract Res 24 (1990) 251-258
    • (1990) J Psychother Pract Res , vol.24 , pp. 251-258
    • Heritch, A.J.1    Henderson, K.2    Westfall, T.C.3
  • 21
    • 0027378270 scopus 로고
    • Changes in basal and stimulated release of endogenous serotonin from different nuclei of rats subjected to two models of depression
    • Jaffe E., De Frias V., and Ibarra C. Changes in basal and stimulated release of endogenous serotonin from different nuclei of rats subjected to two models of depression. Neurosci Lett 162 (1993) 157-160
    • (1993) Neurosci Lett , vol.162 , pp. 157-160
    • Jaffe, E.1    De Frias, V.2    Ibarra, C.3
  • 23
    • 0036304285 scopus 로고    scopus 로고
    • Toward a comprehensive developmental model for major depression in women
    • Kendler K.S., Gardner C.O., and Prescott C.A. Toward a comprehensive developmental model for major depression in women. Am J Psychiatry 159 (2002) 1133-1145
    • (2002) Am J Psychiatry , vol.159 , pp. 1133-1145
    • Kendler, K.S.1    Gardner, C.O.2    Prescott, C.A.3
  • 24
    • 33846344311 scopus 로고    scopus 로고
    • Depressive behavior and selective downregulation of serotonin receptor expression after early-life seizures: reversal by environmental enrichment
    • Koh S., Magid R., Chung H., Stine C.D., and Wilson D.N. Depressive behavior and selective downregulation of serotonin receptor expression after early-life seizures: reversal by environmental enrichment. Epilepsy Behav 10 (2007) 26-31
    • (2007) Epilepsy Behav , vol.10 , pp. 26-31
    • Koh, S.1    Magid, R.2    Chung, H.3    Stine, C.D.4    Wilson, D.N.5
  • 25
    • 0035985558 scopus 로고    scopus 로고
    • Psychological stress and environmental adaptation in enriched vs. impoverished housed rats
    • Larsson F., Winblad B., and Mohammed A.H. Psychological stress and environmental adaptation in enriched vs. impoverished housed rats. Pharmacol Biochem Behav 73 (2002) 193-207
    • (2002) Pharmacol Biochem Behav , vol.73 , pp. 193-207
    • Larsson, F.1    Winblad, B.2    Mohammed, A.H.3
  • 26
    • 22144473378 scopus 로고    scopus 로고
    • Developmental determinants of sensitivity and resistance to stress
    • Levine S. Developmental determinants of sensitivity and resistance to stress. Psychoneuroendocrinology 30 (2005) 939-946
    • (2005) Psychoneuroendocrinology , vol.30 , pp. 939-946
    • Levine, S.1
  • 27
    • 0020578440 scopus 로고
    • Long term isolation in the rat induces opposite changes in binding of α-1 and α-2 adrenoceptors in the brain and vas deferens
    • Lopez de Ceballos M., Guisado E., Sanchez-Blazquez P., Garzon J., and del Rio J. Long term isolation in the rat induces opposite changes in binding of α-1 and α-2 adrenoceptors in the brain and vas deferens. Neurosci Lett 39 (1983) 217-222
    • (1983) Neurosci Lett , vol.39 , pp. 217-222
    • Lopez de Ceballos, M.1    Guisado, E.2    Sanchez-Blazquez, P.3    Garzon, J.4    del Rio, J.5
  • 28
    • 0000587671 scopus 로고
    • The serotonin hypothesis of major depression
    • Bloom F., and Kupfer D. (Eds), Raven, New York
    • Maes M., and Meltzer H.Y. The serotonin hypothesis of major depression. In: Bloom F., and Kupfer D. (Eds). Psychopharmacology: The fourth generation of progress (1995), Raven, New York 933-944
    • (1995) Psychopharmacology: The fourth generation of progress , pp. 933-944
    • Maes, M.1    Meltzer, H.Y.2
  • 29
    • 10444275641 scopus 로고    scopus 로고
    • Effects of postnatal cocaine exposure and environmental enrichment on rat behavior in a forced swim test
    • Magalhaes A., Summavielle T., Tavares M.A., and de Sousa L. Effects of postnatal cocaine exposure and environmental enrichment on rat behavior in a forced swim test. Ann N Y Acad Sci 1025 (2004) 619-629
    • (2004) Ann N Y Acad Sci , vol.1025 , pp. 619-629
    • Magalhaes, A.1    Summavielle, T.2    Tavares, M.A.3    de Sousa, L.4
  • 30
    • 0036837646 scopus 로고    scopus 로고
    • Influence of aging and social isolation on changes in brain monoamine turnover and biosynthesis of rats elicited by novelty stress
    • Miura H., Qiao H., and Ohta T. Influence of aging and social isolation on changes in brain monoamine turnover and biosynthesis of rats elicited by novelty stress. Synapse 46 (2002) 116-124
    • (2002) Synapse , vol.46 , pp. 116-124
    • Miura, H.1    Qiao, H.2    Ohta, T.3
  • 31
    • 14644393040 scopus 로고    scopus 로고
    • Effects of fluvoxamine on levels of dopamine, serotonin, and their metabolites in the hippocampus elicited by isolation housing and novelty stress in adult rats
    • Miura H., Qiao H., Kitagami T., Ohta T., and Ozaki N. Effects of fluvoxamine on levels of dopamine, serotonin, and their metabolites in the hippocampus elicited by isolation housing and novelty stress in adult rats. Int J Neurosci 115 (2005) 367-378
    • (2005) Int J Neurosci , vol.115 , pp. 367-378
    • Miura, H.1    Qiao, H.2    Kitagami, T.3    Ohta, T.4    Ozaki, N.5
  • 32
    • 0037016342 scopus 로고    scopus 로고
    • An enriched environment increases noradrenaline concentration in the mouse brain
    • Naka F., Shiga T., Yaguchi M., and Okado N. An enriched environment increases noradrenaline concentration in the mouse brain. Brain Res 924 (2002) 124-126
    • (2002) Brain Res , vol.924 , pp. 124-126
    • Naka, F.1    Shiga, T.2    Yaguchi, M.3    Okado, N.4
  • 33
    • 0033220002 scopus 로고    scopus 로고
    • Serotonergic mediation of the effects of fluoxetine, but not desipramine, in rats forced swimming test
    • Page M.E., Dekte M.J., Dalvi A., Kirby L.G., and Lucki I. Serotonergic mediation of the effects of fluoxetine, but not desipramine, in rats forced swimming test. Psychopharmacology 147 (1999) 162-167
    • (1999) Psychopharmacology , vol.147 , pp. 162-167
    • Page, M.E.1    Dekte, M.J.2    Dalvi, A.3    Kirby, L.G.4    Lucki, I.5
  • 34
    • 0037221748 scopus 로고    scopus 로고
    • Simultaneous analyses of the neurochemical and behavioural effects of the norepinephrine reuptake inhibitor reboxetine in a rat model of antidepressant action
    • Page M.E., Brown K., and Lucki I. Simultaneous analyses of the neurochemical and behavioural effects of the norepinephrine reuptake inhibitor reboxetine in a rat model of antidepressant action. Psychopharmacology 165 (2003) 194-201
    • (2003) Psychopharmacology , vol.165 , pp. 194-201
    • Page, M.E.1    Brown, K.2    Lucki, I.3
  • 35
    • 0028933405 scopus 로고
    • Low parental care as a risk factor to lifetime depression in a community sample
    • Parker G., Hadzi-Pavlovic D., Greenwald S., and Weissman M. Low parental care as a risk factor to lifetime depression in a community sample. J Affect Disord 33 (1995) 173-180
    • (1995) J Affect Disord , vol.33 , pp. 173-180
    • Parker, G.1    Hadzi-Pavlovic, D.2    Greenwald, S.3    Weissman, M.4
  • 36
    • 2342627257 scopus 로고    scopus 로고
    • Long-term effects of the periadolescent environment on exploratory activity and aggressive behaviour in mice: social versus physical enrichment
    • Pietropaolo S., Branchi I., Cirulli F., Chiarotti F., Aloe L., and Alleva E. Long-term effects of the periadolescent environment on exploratory activity and aggressive behaviour in mice: social versus physical enrichment. Physiol Behav 81 (2004) 443-453
    • (2004) Physiol Behav , vol.81 , pp. 443-453
    • Pietropaolo, S.1    Branchi, I.2    Cirulli, F.3    Chiarotti, F.4    Aloe, L.5    Alleva, E.6
  • 37
    • 0031807854 scopus 로고    scopus 로고
    • Psychoneuroendocrinology of depression. Hypothalamic-pituitary-adrenal axis
    • Plotsky P.M., Owen M.J., and Nemeroff C.B. Psychoneuroendocrinology of depression. Hypothalamic-pituitary-adrenal axis. Psychiatr Clin North Am 21 (1998) 293-307
    • (1998) Psychiatr Clin North Am , vol.21 , pp. 293-307
    • Plotsky, P.M.1    Owen, M.J.2    Nemeroff, C.B.3
  • 38
    • 19944421824 scopus 로고    scopus 로고
    • Long-term effects of early-life environmental manipulations in rodents and primates: potential animal models in depression research
    • Pryce C.R., Rüedi-Bettschen D.C., Dettling A.C., Weston A., Russig H., Ferger B., et al. Long-term effects of early-life environmental manipulations in rodents and primates: potential animal models in depression research. Neurosci Biobehav Rev 29 (2005) 649-674
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 649-674
    • Pryce, C.R.1    Rüedi-Bettschen, D.C.2    Dettling, A.C.3    Weston, A.4    Russig, H.5    Ferger, B.6
  • 39
    • 0034892425 scopus 로고    scopus 로고
    • Behavioral and neurochemical effects of anpirtoline and citalopram in isolated and group housed mice
    • Rilke O., Will K., Jähkel M., and Oehler J. Behavioral and neurochemical effects of anpirtoline and citalopram in isolated and group housed mice. Prog Neuro-Psychopharmacol Biol Psychiatry 25 (2001) 1125-1144
    • (2001) Prog Neuro-Psychopharmacol Biol Psychiatry , vol.25 , pp. 1125-1144
    • Rilke, O.1    Will, K.2    Jähkel, M.3    Oehler, J.4
  • 40
    • 0029879274 scopus 로고    scopus 로고
    • Behavioural and neurochemical effects of early social deprivation in the rat
    • Robbins T.W., Jones G.H., and Wilkinson L.S. Behavioural and neurochemical effects of early social deprivation in the rat. J Psychopharmacol 10 (1996) 39-47
    • (1996) J Psychopharmacol , vol.10 , pp. 39-47
    • Robbins, T.W.1    Jones, G.H.2    Wilkinson, L.S.3
  • 41
    • 0033848019 scopus 로고    scopus 로고
    • Los fármacos antidepresivos y la conducta de inmovilidad en la prueba de nado forzado: Participación de los sistemas de neurotransmisión
    • Rodríguez-Landa J.F., and Contreras C.M. Los fármacos antidepresivos y la conducta de inmovilidad en la prueba de nado forzado: Participación de los sistemas de neurotransmisión. Arch Neurocienc 5 (2000) 74-83
    • (2000) Arch Neurocienc , vol.5 , pp. 74-83
    • Rodríguez-Landa, J.F.1    Contreras, C.M.2
  • 42
    • 0029893652 scopus 로고    scopus 로고
    • Psychobiology of plasticity: effects of training and experience on brain and behavior
    • Rosenzweig M.R., and Bennett E.L. Psychobiology of plasticity: effects of training and experience on brain and behavior. Behav Brain Res 78 (1996) 57-65
    • (1996) Behav Brain Res , vol.78 , pp. 57-65
    • Rosenzweig, M.R.1    Bennett, E.L.2
  • 43
    • 0035826517 scopus 로고    scopus 로고
    • Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model
    • Russo-Neustadt A., Ha T., Ramírez R., and Kesslak J.P. Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model. Behav Brain Res 120 (2001) 87-95
    • (2001) Behav Brain Res , vol.120 , pp. 87-95
    • Russo-Neustadt, A.1    Ha, T.2    Ramírez, R.3    Kesslak, J.P.4
  • 44
    • 0035985570 scopus 로고    scopus 로고
    • Dissociable effects of isolation rearing and environmental enrichment on exploration, spatial learning and HPA activity in adult rats
    • Schrijver N.C., Bahr N.I., Weiss I.C., and Wurbel H. Dissociable effects of isolation rearing and environmental enrichment on exploration, spatial learning and HPA activity in adult rats. Pharmacol Biochem Behav 73 (2002) 209-224
    • (2002) Pharmacol Biochem Behav , vol.73 , pp. 209-224
    • Schrijver, N.C.1    Bahr, N.I.2    Weiss, I.C.3    Wurbel, H.4
  • 46
    • 0034576650 scopus 로고    scopus 로고
    • Neural consequences of environmental enrichment
    • Van Praag H., Kempermann G., and Gage F.H. Neural consequences of environmental enrichment. Nat Neurosci 1 (2000) 191-198
    • (2000) Nat Neurosci , vol.1 , pp. 191-198
    • Van Praag, H.1    Kempermann, G.2    Gage, F.H.3
  • 47
    • 0033913927 scopus 로고    scopus 로고
    • Strain differences in the isolation-induced effects on prepulse inhibition of the acoustic startle response and on locomotor activity
    • Weiss I.C., Di Iorio L., Feldon J., and Domeney A.M. Strain differences in the isolation-induced effects on prepulse inhibition of the acoustic startle response and on locomotor activity. Behav Neurosci 114 (2000) 364-373
    • (2000) Behav Neurosci , vol.114 , pp. 364-373
    • Weiss, I.C.1    Di Iorio, L.2    Feldon, J.3    Domeney, A.M.4
  • 48
    • 2942587380 scopus 로고    scopus 로고
    • Effect of social isolation on stress-related behavioural and neuroendocrine state in the rat
    • Weiss I.C., Pryce C.R., Jongen-Relo A.L., Bahr N.I., and Feldon J. Effect of social isolation on stress-related behavioural and neuroendocrine state in the rat. Behav Brain Res 152 (2004) 279-295
    • (2004) Behav Brain Res , vol.152 , pp. 279-295
    • Weiss, I.C.1    Pryce, C.R.2    Jongen-Relo, A.L.3    Bahr, N.I.4    Feldon, J.5
  • 49
    • 31444438416 scopus 로고    scopus 로고
    • Beneficial effects of exercise and its molecular mechanisms on depression in rats
    • Zheng H., Liu Y., Li W., Yang B., Chen D., Wang X., et al. Beneficial effects of exercise and its molecular mechanisms on depression in rats. Behav Brain Res 168 (2006) 47-55
    • (2006) Behav Brain Res , vol.168 , pp. 47-55
    • Zheng, H.1    Liu, Y.2    Li, W.3    Yang, B.4    Chen, D.5    Wang, X.6
  • 50
    • 0035105420 scopus 로고    scopus 로고
    • Enrichment-dependent differences in novelty exploration in rats can be explained by habituation
    • Zimmermann A., Stauffacher M., Langhans W., and Würbel H. Enrichment-dependent differences in novelty exploration in rats can be explained by habituation. Behav Brain Res 121 (2001) 11-20
    • (2001) Behav Brain Res , vol.121 , pp. 11-20
    • Zimmermann, A.1    Stauffacher, M.2    Langhans, W.3    Würbel, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.