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Volumn 32, Issue 6, 2012, Pages 1197-1219

Immunotherapeutic strategies for cancer treatment: A novel protein transfer approach for cancer vaccine development

Author keywords

Cancer immunotherapy; Cancer vaccine; Cytokines; Glycosylphosphatidylinositol (GPI); Immunostimulatory molecules; Protein transfer

Indexed keywords

ALEMTUZUMAB; ALPHA2A INTERFERON; BEVACIZUMAB; CANCER VACCINE; CETUXIMAB; DENDRITIC CELL VACCINE; DOCETAXEL; FLUOROURACIL; GEMTUZUMAB OZOGAMICIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR VACCINE; IBRITUMOMAB TIUXETAN; INTERLEUKIN 15; INTERLEUKIN 2; MONOCLONAL ANTIBODY; OFATUMUMAB; PANITUMOMAB; PREDNISONE; RITUXIMAB; SIPULEUCEL T; THALIDOMIDE; TOSITUMOMAB; TRASTUZUMAB; UNCLASSIFIED DRUG;

EID: 84867461170     PISSN: 01986325     EISSN: 10981128     Source Type: Journal    
DOI: 10.1002/med.20237     Document Type: Article
Times cited : (15)

References (170)
  • 1
    • 1842430906 scopus 로고    scopus 로고
    • Shedding light on immunotherapy for cancer
    • Rosenberg SA. Shedding light on immunotherapy for cancer. N Eng J Med. 2004;350:1461-1463.
    • (2004) N Eng J Med , vol.350 , pp. 1461-1463
    • Rosenberg, S.A.1
  • 3
    • 2642683198 scopus 로고    scopus 로고
    • Simultaneous humoral and cellular immune response against cancer-testis antigen NY-ESO-1: Definition of human histocompatibility leukocyte antigen (HLA)-A2-binding peptide epitopes
    • Jäger E, Chen YT, Drijfhout JW, Karbach J, Ringhoffer M, Jäger D, Arand M, Wada H, Noguchi Y, Stockert E, Old LJ, Knuth A. Simultaneous humoral and cellular immune response against cancer-testis antigen NY-ESO-1: Definition of human histocompatibility leukocyte antigen (HLA)-A2-binding peptide epitopes. J Exp Med. 1998;187:265-270.
    • (1998) J Exp Med , vol.187 , pp. 265-270
    • Jäger, E.1    Chen, Y.T.2    Drijfhout, J.W.3    Karbach, J.4    Ringhoffer, M.5    Jäger, D.6    Arand, M.7    Wada, H.8    Noguchi, Y.9    Stockert, E.10    Old, L.J.11    Knuth, A.12
  • 4
    • 0002682374 scopus 로고
    • Principles of tumor immunity: Tumor antigens
    • De Vita VT, Hellman S, Rosenberg SA, editors. Philadelphia: J.B. Lippincott Co.
    • Hellstrom KE, Hellstrom I. Principles of tumor immunity: Tumor antigens. In: De Vita VT, Hellman S, Rosenberg SA, editors. The biologic therapy of cancer. Philadelphia: J.B. Lippincott Co.; 1991. pp 35-52.
    • (1991) The biologic therapy of cancer , pp. 35-52
    • Hellstrom, K.E.1    Hellstrom, I.2
  • 5
    • 0024327899 scopus 로고
    • Clonal expansion versus functional clonal inactivation: A costimulatory signaling pathway determines the outcome of T cell antigen receptor occupancy
    • Mueller DL, Jenkins MK, Schwartz RH. Clonal expansion versus functional clonal inactivation: A costimulatory signaling pathway determines the outcome of T cell antigen receptor occupancy. Annu Rev Immunol. 1989;7:445-480.
    • (1989) Annu Rev Immunol , vol.7 , pp. 445-480
    • Mueller, D.L.1    Jenkins, M.K.2    Schwartz, R.H.3
  • 6
    • 0027254103 scopus 로고
    • Accessory cell-derived signals required for T cell activation
    • Johnson JG, Jenkins MK. Accessory cell-derived signals required for T cell activation. Immunol Res. 1993;12:48-64.
    • (1993) Immunol Res , vol.12 , pp. 48-64
    • Johnson, J.G.1    Jenkins, M.K.2
  • 7
  • 8
    • 0027247372 scopus 로고
    • Distribution and function of lymphocyte surface antigens. Molecules costimulating T lymphocyte activation and function
    • Lanier LL. Distribution and function of lymphocyte surface antigens. Molecules costimulating T lymphocyte activation and function. Ann NY Acad Sci. 1993;677:86-93.
    • (1993) Ann NY Acad Sci , vol.677 , pp. 86-93
    • Lanier, L.L.1
  • 9
    • 79959579176 scopus 로고
    • Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody
    • Jenkins MK, Chen CA, Jung G, Mueller DL, Schwartz RH. Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody. J Immunol. 1990;170:3806-3811.
    • (1990) J Immunol , vol.170 , pp. 3806-3811
    • Jenkins, M.K.1    Chen, C.A.2    Jung, G.3    Mueller, D.L.4    Schwartz, R.H.5
  • 10
    • 0027392843 scopus 로고
    • Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells
    • Townsend SE, Allison JP. Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells. Science. 1993;259:368-370.
    • (1993) Science , vol.259 , pp. 368-370
    • Townsend, S.E.1    Allison, J.P.2
  • 11
    • 0028263666 scopus 로고
    • Costimulation of tumor reactive CD4+ and CD8+ T lymphocytes by B7, a natural ligand for CD28, can be used to treat established mouse melanoma
    • Li Y, McGowan P, Hellstrom I, Hellstrom KE, Chen L. Costimulation of tumor reactive CD4+ and CD8+ T lymphocytes by B7, a natural ligand for CD28, can be used to treat established mouse melanoma. J Immunol. 1994;153:421-428.
    • (1994) J Immunol , vol.153 , pp. 421-428
    • Li, Y.1    McGowan, P.2    Hellstrom, I.3    Hellstrom, K.E.4    Chen, L.5
  • 12
    • 0033568302 scopus 로고    scopus 로고
    • Human fibroblast transduced with CD80 or CD86 efficiently trans-costimulate CD4+ and CD8+ T lymphocytes in HLA-restricted reactions: Implications for immune augmentation cancer therapy and autoimmunity
    • Smythe JA, Fink PD, Logan GJ, Lees J, Rowe J, Alexander IE. Human fibroblast transduced with CD80 or CD86 efficiently trans-costimulate CD4+ and CD8+ T lymphocytes in HLA-restricted reactions: Implications for immune augmentation cancer therapy and autoimmunity. J Immunol. 1999;163:3239-3249.
    • (1999) J Immunol , vol.163 , pp. 3239-3249
    • Smythe, J.A.1    Fink, P.D.2    Logan, G.J.3    Lees, J.4    Rowe, J.5    Alexander, I.E.6
  • 13
    • 0035961504 scopus 로고    scopus 로고
    • Development of therapeutic vaccines by direct modification of cell membranes from surgically removed human tumor tissue with immunostimulatory molecules
    • Poloso N, Nagarajan S, Bumgarner GW, Selvaraj P. Development of therapeutic vaccines by direct modification of cell membranes from surgically removed human tumor tissue with immunostimulatory molecules. Vaccine. 2001;19:2029-2038.
    • (2001) Vaccine , vol.19 , pp. 2029-2038
    • Poloso, N.1    Nagarajan, S.2    Bumgarner, G.W.3    Selvaraj, P.4
  • 15
    • 0025981518 scopus 로고
    • Transforming growth factor-beta-induced inhibition of T cell function: Susceptibility difference in T cells of various phenotypes and functions and its relevance to immunosuppression in the tumor-bearing state
    • Tada T, Ohzeki S, Utsumi K, Takiuchi H, Muramatsu M, Li XF, Shimizu J, Fujiwara H, Hamaoka T. Transforming growth factor-beta-induced inhibition of T cell function: Susceptibility difference in T cells of various phenotypes and functions and its relevance to immunosuppression in the tumor-bearing state. J Immunol. 1991;146:1077-1082.
    • (1991) J Immunol , vol.146 , pp. 1077-1082
    • Tada, T.1    Ohzeki, S.2    Utsumi, K.3    Takiuchi, H.4    Muramatsu, M.5    Li, X.F.6    Shimizu, J.7    Fujiwara, H.8    Hamaoka, T.9
  • 16
    • 0028347925 scopus 로고
    • Production of IL-10 by melanoma cells: Examination of its role in immunosuppression mediated by melanoma
    • Chen Q, Daniel V, Maher DW, Hersey P. Production of IL-10 by melanoma cells: Examination of its role in immunosuppression mediated by melanoma. Int J Clin Oncol. 1994;56:755-760.
    • (1994) Int J Clin Oncol , vol.56 , pp. 755-760
    • Chen, Q.1    Daniel, V.2    Maher, D.W.3    Hersey, P.4
  • 18
    • 43949105866 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance
    • Sakaguchi S, Yamaguchi T, Nomura T, Ono M. Regulatory T cells and immune tolerance. Cell. 2008;133:775-787.
    • (2008) Cell , vol.133 , pp. 775-787
    • Sakaguchi, S.1    Yamaguchi, T.2    Nomura, T.3    Ono, M.4
  • 19
  • 20
    • 31644432589 scopus 로고    scopus 로고
    • Regulatory T cells in immune surveillance and treatment of cancer
    • Yamaguchi T, Sakaguchi S. Regulatory T cells in immune surveillance and treatment of cancer. Semin Cancer Biol. 2006;16:115-123.
    • (2006) Semin Cancer Biol , vol.16 , pp. 115-123
    • Yamaguchi, T.1    Sakaguchi, S.2
  • 21
    • 77955515915 scopus 로고    scopus 로고
    • Depletion of regulatory T cells by anti-GITR mAb as a novel mechanism for cancer immunotherapy
    • Coe D, Begom S, Addey C, White M, Dyson J, Chai J. Depletion of regulatory T cells by anti-GITR mAb as a novel mechanism for cancer immunotherapy. Cancer Immunol Immunother. 2010;59:1367-1377.
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 1367-1377
    • Coe, D.1    Begom, S.2    Addey, C.3    White, M.4    Dyson, J.5    Chai, J.6
  • 22
    • 84867456804 scopus 로고    scopus 로고
    • Tumor-derived soluble glucocorticoid-induced TNF-related protein (GITR) ligand diminishes antitumor reactivity of NK cells
    • Krusch M, Baltz KM, Bringmann A, Brossart P, Salih HR. Tumor-derived soluble glucocorticoid-induced TNF-related protein (GITR) ligand diminishes antitumor reactivity of NK cells. FASEB J. 2008;22:1079.25-
    • (2008) FASEB J , vol.22 , pp. 107925
    • Krusch, M.1    Baltz, K.M.2    Bringmann, A.3    Brossart, P.4    Salih, H.R.5
  • 23
    • 77953611288 scopus 로고    scopus 로고
    • Myeloid derived suppressor cells and their role in tolerance induction in cancer
    • Fujimura T, Mahnke K, Enk AH. Myeloid derived suppressor cells and their role in tolerance induction in cancer. J Dermatol Sci. 2010;59:1-6.
    • (2010) J Dermatol Sci , vol.59 , pp. 1-6
    • Fujimura, T.1    Mahnke, K.2    Enk, A.H.3
  • 24
    • 29144504335 scopus 로고    scopus 로고
    • CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1b-secreting cells
    • Song X, Krelin Y, Dvorkin T, Bjorkdahi O, Segal S, Dinarello CA, Voronov E, Apte RN. CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1b-secreting cells. J Immunol. 2005;175:8200-8208.
    • (2005) J Immunol , vol.175 , pp. 8200-8208
    • Song, X.1    Krelin, Y.2    Dvorkin, T.3    Bjorkdahi, O.4    Segal, S.5    Dinarello, C.A.6    Voronov, E.7    Apte, R.N.8
  • 26
    • 33846891555 scopus 로고    scopus 로고
    • Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma
    • Ochoa AC, Zea HA, Hernandex C, Rodriguez PC. Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma. Clin Cancer Res. 2007;13:721s-725s.
    • (2007) Clin Cancer Res , vol.13
    • Ochoa, A.C.1    Zea, H.A.2    Hernandex, C.3    Rodriguez, P.C.4
  • 27
    • 41149148269 scopus 로고    scopus 로고
    • Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: Mechanisms and therapeutic perspectives
    • Rodriguez PC, Ochoa AC. Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: Mechanisms and therapeutic perspectives. Immunol Rev. 2008;222:180-191.
    • (2008) Immunol Rev , vol.222 , pp. 180-191
    • Rodriguez, P.C.1    Ochoa, A.C.2
  • 28
    • 47949090079 scopus 로고    scopus 로고
    • The role of myeloid cells in the promotion of tumor angiogenesis
    • Murdoch C, Muthana M, Coffelt SB, Lewis CE. The role of myeloid cells in the promotion of tumor angiogenesis. Nat Rev Cancer. 2008;8:618-631.
    • (2008) Nat Rev Cancer , vol.8 , pp. 618-631
    • Murdoch, C.1    Muthana, M.2    Coffelt, S.B.3    Lewis, C.E.4
  • 29
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol. 2009;9:162-174.
    • (2009) Nat Rev Immunol , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 30
    • 77952231121 scopus 로고    scopus 로고
    • Induction of lymphoid like stroma and immune escape by tumors that express the chemokine CCL21
    • Shields JD, Kourtis IC, Tomei AA, Roberts JM, Swartz MA. Induction of lymphoid like stroma and immune escape by tumors that express the chemokine CCL21. Science. 2010;328:697-698.
    • (2010) Science , vol.328 , pp. 697-698
    • Shields, J.D.1    Kourtis, I.C.2    Tomei, A.A.3    Roberts, J.M.4    Swartz, M.A.5
  • 32
    • 67650495415 scopus 로고    scopus 로고
    • IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
    • Wang L, Yi T, Kortylewski M, Pardoll DM, Zeng D, Yu H. IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med. 2009;206:1457-1464.
    • (2009) J Exp Med , vol.206 , pp. 1457-1464
    • Wang, L.1    Yi, T.2    Kortylewski, M.3    Pardoll, D.M.4    Zeng, D.5    Yu, H.6
  • 34
    • 0034909080 scopus 로고    scopus 로고
    • Inoculation of human interleukin-17 gene-transfected meth-A fibrosarcoma cells induces T cell-dependent tumor-specific immunity in mice
    • Hirahara N, Nio Y, Sasaki S, Minari Y, Takamura M, Iguchi C, Dong M, Yamasawa K, Tamura K. Inoculation of human interleukin-17 gene-transfected meth-A fibrosarcoma cells induces T cell-dependent tumor-specific immunity in mice. Oncology. 2001;61:79-89.
    • (2001) Oncology , vol.61 , pp. 79-89
    • Hirahara, N.1    Nio, Y.2    Sasaki, S.3    Minari, Y.4    Takamura, M.5    Iguchi, C.6    Dong, M.7    Yamasawa, K.8    Tamura, K.9
  • 35
    • 67651094058 scopus 로고    scopus 로고
    • Endogenous IL-17 contributes to reduced tumor growth and metastasis
    • Kryczek I, Wei S, Szeliga W, Vatan L, Zou W. Endogenous IL-17 contributes to reduced tumor growth and metastasis. Blood. 2009;114:357-359.
    • (2009) Blood , vol.114 , pp. 357-359
    • Kryczek, I.1    Wei, S.2    Szeliga, W.3    Vatan, L.4    Zou, W.5
  • 36
    • 77949329050 scopus 로고    scopus 로고
    • Tumor microenvironments direct the recruitment and expansion of human Th17 cells
    • Su X, Ye J, Hsueh EC, Zhang Y, Hoft DF, Peng G. Tumor microenvironments direct the recruitment and expansion of human Th17 cells. J Immunol. 2010;184:1630-1641.
    • (2010) J Immunol , vol.184 , pp. 1630-1641
    • Su, X.1    Ye, J.2    Hsueh, E.C.3    Zhang, Y.4    Hoft, D.F.5    Peng, G.6
  • 37
    • 67650446560 scopus 로고    scopus 로고
    • Malignant B cells skew the balance of regulatory T cells and Th17 cells in B-cell non-Hodgkin's lymphoma
    • Yang ZZ, Novak AJ, Ziesmer SC, Witzig TE, Ansell SM. Malignant B cells skew the balance of regulatory T cells and Th17 cells in B-cell non-Hodgkin's lymphoma. Cancer Res. 2009;69:5522-5530.
    • (2009) Cancer Res , vol.69 , pp. 5522-5530
    • Yang, Z.Z.1    Novak, A.J.2    Ziesmer, S.C.3    Witzig, T.E.4    Ansell, S.M.5
  • 38
    • 63949083529 scopus 로고    scopus 로고
    • The effects of trastuzumab on the CD4+ CD25+ FoxP3+ and CD4+ IL17+ T-cell axis in patients with breast cancer
    • Herlock C, Scott B, Dyson PJ, Morishita M, Coombes RC, Savage P, Stebbing J. The effects of trastuzumab on the CD4+ CD25+ FoxP3+ and CD4+ IL17+ T-cell axis in patients with breast cancer. Br J Cancer. 2009;100:1061-1067.
    • (2009) Br J Cancer , vol.100 , pp. 1061-1067
    • Herlock, C.1    Scott, B.2    Dyson, P.J.3    Morishita, M.4    Coombes, R.C.5    Savage, P.6    Stebbing, J.7
  • 39
    • 0033051081 scopus 로고    scopus 로고
    • Dendritic cell vaccines for cancer immunotherapy
    • Timmerman JM, Levy R. Dendritic cell vaccines for cancer immunotherapy. Annu Rev Med. 1999;50:507-529.
    • (1999) Annu Rev Med , vol.50 , pp. 507-529
    • Timmerman, J.M.1    Levy, R.2
  • 40
    • 0034121654 scopus 로고    scopus 로고
    • Dendritic cells in cancer immunotherapy
    • Fong L, Engleman EG. Dendritic cells in cancer immunotherapy. Annu Rev Immunol. 2000;18:245-273.
    • (2000) Annu Rev Immunol , vol.18 , pp. 245-273
    • Fong, L.1    Engleman, E.G.2
  • 41
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • Rosenberg SA, Yang CJ, Restifo PN. Cancer immunotherapy: Moving beyond current vaccines. Nat Med. 2004;10:909-915.
    • (2004) Nat Med , vol.10 , pp. 909-915
    • Rosenberg, S.A.1    Yang, C.J.2    Restifo, P.N.3
  • 42
    • 0031960301 scopus 로고    scopus 로고
    • Cancer vaccines
    • Pardoll DM. Cancer vaccines. Nat Med. 1998;4:525-531.
    • (1998) Nat Med , vol.4 , pp. 525-531
    • Pardoll, D.M.1
  • 43
    • 4644274088 scopus 로고    scopus 로고
    • The first 1000 dendritic cell vaccines
    • Ridgeway D. The first 1000 dendritic cell vaccines. Cancer Invest. 2003;21:876-886.
    • (2003) Cancer Invest , vol.21 , pp. 876-886
    • Ridgeway, D.1
  • 44
    • 0033818096 scopus 로고    scopus 로고
    • The dendritic cell and human cancer vaccines
    • Dallal RM, Lotze MT. The dendritic cell and human cancer vaccines. Curr Opin Immunol. 2000;12:583-588.
    • (2000) Curr Opin Immunol , vol.12 , pp. 583-588
    • Dallal, R.M.1    Lotze, M.T.2
  • 45
    • 0028208910 scopus 로고
    • Effective tumor vaccine generated by fusion of hepatoma cells with activated B cells
    • Guo Y, Wu M, Chen H, Wang X, Liu G, Li G, Ma J, Sy M. Effective tumor vaccine generated by fusion of hepatoma cells with activated B cells. Science. 1994;263:518-520.
    • (1994) Science , vol.263 , pp. 518-520
    • Guo, Y.1    Wu, M.2    Chen, H.3    Wang, X.4    Liu, G.5    Li, G.6    Ma, J.7    Sy, M.8
  • 46
    • 0030904482 scopus 로고    scopus 로고
    • Induction of antitumor activity by immunization with fusions of dendritic cells and carcinoma cells
    • Gong J, Chen D, Kashowaba M, Kufe D. Induction of antitumor activity by immunization with fusions of dendritic cells and carcinoma cells. Nat Med. 1997;3:558-561.
    • (1997) Nat Med , vol.3 , pp. 558-561
    • Gong, J.1    Chen, D.2    Kashowaba, M.3    Kufe, D.4
  • 49
    • 0031941423 scopus 로고    scopus 로고
    • Vaccination of melanoma patients with peptide-or tumor lysate-pulsed dendritic cells
    • Nestle FO, Alijagic S, Gilliet M, Sun Y, Grabbe S, Dummer R, Burg G. Vaccination of melanoma patients with peptide-or tumor lysate-pulsed dendritic cells. Nat Med. 1998;4:328-332.
    • (1998) Nat Med , vol.4 , pp. 328-332
    • Nestle, F.O.1    Alijagic, S.2    Gilliet, M.3    Sun, Y.4    Grabbe, S.5    Dummer, R.6    Burg, G.7
  • 50
    • 33644636996 scopus 로고    scopus 로고
    • Therapeutic cancer vaccines
    • Srivastava PK. Therapeutic cancer vaccines. Curr Opin Immunol. 2006;18:201-205.
    • (2006) Curr Opin Immunol , vol.18 , pp. 201-205
    • Srivastava, P.K.1
  • 53
    • 3242747658 scopus 로고    scopus 로고
    • Immunotherapy (APC8015, Provenge) targeting prostatic acid phosphotase can induce durable remission of metastatic androgen-independent prostate cancer: A phase 2 trial
    • Burch PA, Croghan GA, Gastineau DA, Jones LA, Kaur SJ, Kylstra JW, Richardson RL, Valone FH, Vuk-Pavlovic SV. Immunotherapy (APC8015, Provenge) targeting prostatic acid phosphotase can induce durable remission of metastatic androgen-independent prostate cancer: A phase 2 trial. Prostate. 2004;60:197-204.
    • (2004) Prostate , vol.60 , pp. 197-204
    • Burch, P.A.1    Croghan, G.A.2    Gastineau, D.A.3    Jones, L.A.4    Kaur, S.J.5    Kylstra, J.W.6    Richardson, R.L.7    Valone, F.H.8    Vuk-Pavlovic, S.V.9
  • 54
    • 34548190506 scopus 로고    scopus 로고
    • Immunotherapy for prostate cancer using antigen-loaded antigen-presenting cells: APC8015 (Provenge)
    • Harzstark AL, Small EJ. Immunotherapy for prostate cancer using antigen-loaded antigen-presenting cells: APC8015 (Provenge). Expert Opin Biol Ther. 2007;7:1275-1280.
    • (2007) Expert Opin Biol Ther , vol.7 , pp. 1275-1280
    • Harzstark, A.L.1    Small, E.J.2
  • 55
    • 23844479317 scopus 로고    scopus 로고
    • Results of a placebo-controlled phase III trial of immunotherapy with APC8015 for patients with hormone refractory prostate cancer (HRPC)
    • Abstract.
    • Small EJ, Schellhammer PF, Higano CS, Neumanaitis J, Valone F, Hershberg R. Results of a placebo-controlled phase III trial of immunotherapy with APC8015 for patients with hormone refractory prostate cancer (HRPC). ASCO. 2005;4500:Abstract.
    • (2005) ASCO , vol.4500
    • Small, E.J.1    Schellhammer, P.F.2    Higano, C.S.3    Neumanaitis, J.4    Valone, F.5    Hershberg, R.6
  • 57
    • 22144497779 scopus 로고    scopus 로고
    • Vaccines in cancer: GVAX, a GM-CSF gene vaccine
    • Nemunaitis J. Vaccines in cancer: GVAX, a GM-CSF gene vaccine. Expert Rev Vaccines. 2005;4:259-274.
    • (2005) Expert Rev Vaccines , vol.4 , pp. 259-274
    • Nemunaitis, J.1
  • 58
    • 77951277997 scopus 로고    scopus 로고
    • Current status of immunological therapies for prostate cancer
    • Antonarakis ES, Drake CG. Current status of immunological therapies for prostate cancer. Curr Opin Urol. 2010;20:241-246.
    • (2010) Curr Opin Urol , vol.20 , pp. 241-246
    • Antonarakis, E.S.1    Drake, C.G.2
  • 59
    • 70349242210 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting cellular immunotherapy in combination with autologous stem cell transplantation (ASCT) as post remission therapy for acute myeloid leukemia (AML)
    • Borrello IM, Levitsky HI, Stock W, Sher D, Qin L, DeAngelo DJ, Alyea EP, Stone RM, Damon LE, Linker CA, Maslyar DJ, Hege KM. Granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting cellular immunotherapy in combination with autologous stem cell transplantation (ASCT) as post remission therapy for acute myeloid leukemia (AML). Blood. 2009;114:1736-1745.
    • (2009) Blood , vol.114 , pp. 1736-1745
    • Borrello, I.M.1    Levitsky, H.I.2    Stock, W.3    Sher, D.4    Qin, L.5    DeAngelo, D.J.6    Alyea, E.P.7    Stone, R.M.8    Damon, L.E.9    Linker, C.A.10    Maslyar, D.J.11    Hege, K.M.12
  • 60
    • 0024426529 scopus 로고
    • Experience with the use of high-dose interleukin-2 in the treatment of 652 cancer patients
    • Rosenberg SA, Lotze MT, Yang JC. Experience with the use of high-dose interleukin-2 in the treatment of 652 cancer patients. Ann Surg. 1989;210:474-484.
    • (1989) Ann Surg , vol.210 , pp. 474-484
    • Rosenberg, S.A.1    Lotze, M.T.2    Yang, J.C.3
  • 61
    • 0035339880 scopus 로고    scopus 로고
    • High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected state IIB-III melanoma: Results of intergroup trial E1694/S9512/C509801
    • Kirkwood JM, Ibrahim JG, Sosman JA, Sondak VK, Agarwala SS, Ernstoff MS, Rao U. High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected state IIB-III melanoma: Results of intergroup trial E1694/S9512/C509801. J Clin Oncol. 2001;19:2370-2380.
    • (2001) J Clin Oncol , vol.19 , pp. 2370-2380
    • Kirkwood, J.M.1    Ibrahim, J.G.2    Sosman, J.A.3    Sondak, V.K.4    Agarwala, S.S.5    Ernstoff, M.S.6    Rao, U.7
  • 63
    • 0347302952 scopus 로고    scopus 로고
    • Cytokines in cancer pathogenesis and cancer therapy
    • Dranoff G. Cytokines in cancer pathogenesis and cancer therapy. Nature. 2004;4:11-22.
    • (2004) Nature , vol.4 , pp. 11-22
    • Dranoff, G.1
  • 64
    • 0028929682 scopus 로고
    • Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy
    • Fyfe G, Fisher RI, Rosenberg SA, Sznol M, Parkinson DR, Louie AC. Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy. J Clin Oncol. 1995;13:688-696.
    • (1995) J Clin Oncol , vol.13 , pp. 688-696
    • Fyfe, G.1    Fisher, R.I.2    Rosenberg, S.A.3    Sznol, M.4    Parkinson, D.R.5    Louie, A.C.6
  • 65
    • 0026017971 scopus 로고
    • Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis
    • Lenardo MJ. Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis. Nature. 1991;353:858-861.
    • (1991) Nature , vol.353 , pp. 858-861
    • Lenardo, M.J.1
  • 68
    • 16644376744 scopus 로고    scopus 로고
    • Tumor secreting high levels of IL-15 induces specific immunity to low immunogenic colon adenocarcinoma
    • Araki A, Hazama S, Yoshimura K, Yoshino S, Iizuka N, Oka M. Tumor secreting high levels of IL-15 induces specific immunity to low immunogenic colon adenocarcinoma. Int J Mol Med. 2004;14:571-576.
    • (2004) Int J Mol Med , vol.14 , pp. 571-576
    • Araki, A.1    Hazama, S.2    Yoshimura, K.3    Yoshino, S.4    Iizuka, N.5    Oka, M.6
  • 69
    • 11244255868 scopus 로고    scopus 로고
    • IL-15 presentation in the activation of NK-mediated killing, which leads to enhanced tumor immunesurveillance
    • Kobayashi H, Dubois S, Sato N, Sabzevari H, Sakai Y, Waldmann TA, Tagaya Y. IL-15 presentation in the activation of NK-mediated killing, which leads to enhanced tumor immunesurveillance. Blood. 2005;105:721-727.
    • (2005) Blood , vol.105 , pp. 721-727
    • Kobayashi, H.1    Dubois, S.2    Sato, N.3    Sabzevari, H.4    Sakai, Y.5    Waldmann, T.A.6    Tagaya, Y.7
  • 71
    • 76749116183 scopus 로고    scopus 로고
    • Interferon alfa-2a versus combination therapy with interferon alfa-2a, interleukin-2 and fluorouracil in patients with untreated metastatic renal cell carcinoma (MRC RE04/EORTC GU 30012): An open-label randomized trial
    • Gore ME, Griffin CL, Hancock B, Patel PM, Pyle L, Aitchison M, James N, Oliver RT, Mardiak J, Hussain T, Sylvester R, Parmar MK, Royston P, Mulders PF. Interferon alfa-2a versus combination therapy with interferon alfa-2a, interleukin-2 and fluorouracil in patients with untreated metastatic renal cell carcinoma (MRC RE04/EORTC GU 30012): An open-label randomized trial. Lancet. 2010;375:641-648.
    • (2010) Lancet , vol.375 , pp. 641-648
    • Gore, M.E.1    Griffin, C.L.2    Hancock, B.3    Patel, P.M.4    Pyle, L.5    Aitchison, M.6    James, N.7    Oliver, R.T.8    Mardiak, J.9    Hussain, T.10    Sylvester, R.11    Parmar, M.K.12    Royston, P.13    Mulders, P.F.14
  • 74
    • 0023073438 scopus 로고
    • Local administration of interleukin-2 activates lymphocytes from tumor bearing mice to recruit host immunoreactivity and inhibit tumor growth
    • Forni G, Musso T, Santoni A, Giovarelli M. Local administration of interleukin-2 activates lymphocytes from tumor bearing mice to recruit host immunoreactivity and inhibit tumor growth. Prog Clin Biol Res. 1987;244:105-
    • (1987) Prog Clin Biol Res , vol.244 , pp. 105
    • Forni, G.1    Musso, T.2    Santoni, A.3    Giovarelli, M.4
  • 75
    • 0024502120 scopus 로고
    • Murine interleukin-4 displays potent anti-tumor activity in vivo
    • Tepper RI, Pattengale PK, Leder P. Murine interleukin-4 displays potent anti-tumor activity in vivo. Cell. 1989;57:503-512.
    • (1989) Cell , vol.57 , pp. 503-512
    • Tepper, R.I.1    Pattengale, P.K.2    Leder, P.3
  • 76
    • 0025000864 scopus 로고
    • IL-2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity
    • Gansbacher B, Zier K, Daniels B, Cronin K, Bannerji R, Gilboa E. IL-2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity. J Exp Med. 1990;172:1217-1224.
    • (1990) J Exp Med , vol.172 , pp. 1217-1224
    • Gansbacher, B.1    Zier, K.2    Daniels, B.3    Cronin, K.4    Bannerji, R.5    Gilboa, E.6
  • 78
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • Dranoff G, Jaffee E, Lazenby A, Golumbek P, Levitsky HI, Brose K, Jackson V, Hamada H, Pardoll D, Mulligan RC. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA. 1993;90:3539-3543.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3    Golumbek, P.4    Levitsky, H.I.5    Brose, K.6    Jackson, V.7    Hamada, H.8    Pardoll, D.9    Mulligan, R.C.10
  • 80
    • 70449447887 scopus 로고    scopus 로고
    • Targeting TNFalpha for cancer therapy
    • Burton ER, Libutti SK. Targeting TNFalpha for cancer therapy. J Biol. 2009;8:85.1-85.5.
    • (2009) J Biol , vol.8 , pp. 851-855
    • Burton, E.R.1    Libutti, S.K.2
  • 82
    • 44949146378 scopus 로고    scopus 로고
    • Phase II study of combination thalidomide/interleukin-2 therapy plus granulocyte macrophage-colony stimulating factor in patients with metastatic renal cell carcinoma
    • Amato RJ, Malya R, Rawat A. Phase II study of combination thalidomide/interleukin-2 therapy plus granulocyte macrophage-colony stimulating factor in patients with metastatic renal cell carcinoma. Am J Clin Oncol. 2008;31:237-243.
    • (2008) Am J Clin Oncol , vol.31 , pp. 237-243
    • Amato, R.J.1    Malya, R.2    Rawat, A.3
  • 83
    • 65549133424 scopus 로고    scopus 로고
    • A phase I study of granulocyte macrophage colony-stimulating factor (Sargramostim) and escalating doses of thalidomide in patients with high risk malignant melanoma
    • Lutzky J, Weber R, Nunez Y, Gillett M, Spitler L. A phase I study of granulocyte macrophage colony-stimulating factor (Sargramostim) and escalating doses of thalidomide in patients with high risk malignant melanoma. J Immunther. 2009;32:79-85.
    • (2009) J Immunther , vol.32 , pp. 79-85
    • Lutzky, J.1    Weber, R.2    Nunez, Y.3    Gillett, M.4    Spitler, L.5
  • 84
    • 0037264969 scopus 로고    scopus 로고
    • Therapeutic antibodies for human diseases at the dawn of the twenty-first century
    • Brekke OH, Sandlie I. Therapeutic antibodies for human diseases at the dawn of the twenty-first century. Nat Rev Drug Discov. 2003;2:52-62.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 52-62
    • Brekke, O.H.1    Sandlie, I.2
  • 85
    • 34247876138 scopus 로고    scopus 로고
    • Development trends for monoclonal antibody cancer therapeutics
    • Reichert JM, Valge-Archer V. Development trends for monoclonal antibody cancer therapeutics. Nat Rev Drug Discov. 2007;6:349-356.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 349-356
    • Reichert, J.M.1    Valge-Archer, V.2
  • 87
    • 0020608528 scopus 로고
    • Human macrophages armed with murine immunoglobulin G2a antibodies to tumors destroy human cancer cells
    • Steplewski Z, Lubeck MD, Koprowski H. Human macrophages armed with murine immunoglobulin G2a antibodies to tumors destroy human cancer cells. Science. 1983;221:865-867.
    • (1983) Science , vol.221 , pp. 865-867
    • Steplewski, Z.1    Lubeck, M.D.2    Koprowski, H.3
  • 88
    • 0036464611 scopus 로고    scopus 로고
    • The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: Evidence of caspase activation and apoptosis induction
    • Byrd JC, Kitada S, Flinn IW, Aron JL, Pearson M, Lucas D, Reed JC. The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: Evidence of caspase activation and apoptosis induction. Blood. 2002;99:1038-1043.
    • (2002) Blood , vol.99 , pp. 1038-1043
    • Byrd, J.C.1    Kitada, S.2    Flinn, I.W.3    Aron, J.L.4    Pearson, M.5    Lucas, D.6    Reed, J.C.7
  • 89
    • 58149357133 scopus 로고    scopus 로고
    • The role of membrane complement regulatory proteins in cancer immunotherapy
    • Yan J, Allendorf DJ, Li B, Yan R, Hansen R, Donev R. The role of membrane complement regulatory proteins in cancer immunotherapy. Adv Exp Med Biol. 2008;632:159-174.
    • (2008) Adv Exp Med Biol , vol.632 , pp. 159-174
    • Yan, J.1    Allendorf, D.J.2    Li, B.3    Yan, R.4    Hansen, R.5    Donev, R.6
  • 91
    • 33745263037 scopus 로고    scopus 로고
    • Rituximab, an anti-CD20 monoclonal antibody: History and mechanism of action
    • Pescovitz MD. Rituximab, an anti-CD20 monoclonal antibody: History and mechanism of action. Am J Transplant. 2006;6:859-866.
    • (2006) Am J Transplant , vol.6 , pp. 859-866
    • Pescovitz, M.D.1
  • 93
    • 76949104717 scopus 로고    scopus 로고
    • Ofatumumab, a human anti-CD20 monoclonal antibody
    • Osterborg A. Ofatumumab, a human anti-CD20 monoclonal antibody. Expert Opin Biol Ther. 2010;10:439-449.
    • (2010) Expert Opin Biol Ther , vol.10 , pp. 439-449
    • Osterborg, A.1
  • 94
    • 34249725061 scopus 로고    scopus 로고
    • Radioimmunotherapy for B-cell lymphoma: Y90 ibritumomab tiuxetan and I(131) tositumomab
    • Davies A. Radioimmunotherapy for B-cell lymphoma: Y90 ibritumomab tiuxetan and I(131) tositumomab. Oncogene. 2007;26:3614-3628.
    • (2007) Oncogene , vol.26 , pp. 3614-3628
    • Davies, A.1
  • 95
    • 36048996657 scopus 로고    scopus 로고
    • Comparison of 90Y-ibritumomab tiuxetan and I31I-tositumomab in clinical practice
    • Jacene H, Filice R, Kasecamp W, Wahl RL. Comparison of 90Y-ibritumomab tiuxetan and I31I-tositumomab in clinical practice. J Nucl Med. 2007;48:1767-1776.
    • (2007) J Nucl Med , vol.48 , pp. 1767-1776
    • Jacene, H.1    Filice, R.2    Kasecamp, W.3    Wahl, R.L.4
  • 97
    • 0036125566 scopus 로고    scopus 로고
    • Level of CD20 expression and efficacy of rituximab treatment in patients with resistant or relapsing B-cell prolymphocytic leukemia and B-cell chronic lymphocytic leukemia
    • Perz J, Topaly J, Fruehauf S, Hensel M, Ho AD. Level of CD20 expression and efficacy of rituximab treatment in patients with resistant or relapsing B-cell prolymphocytic leukemia and B-cell chronic lymphocytic leukemia. Leuk Lymphoma. 2002;43:149-151.
    • (2002) Leuk Lymphoma , vol.43 , pp. 149-151
    • Perz, J.1    Topaly, J.2    Fruehauf, S.3    Hensel, M.4    Ho, A.D.5
  • 98
    • 32044464340 scopus 로고    scopus 로고
    • The shaving reaction: Rituximab/CD20 complexes are removed from mantle cell lymphoma and chronic lymphocytic leukemia cells by THP-1 molecules
    • Beum PV, Kennedy AD, Williams ME, Lindorfer MA, Taylor RP. The shaving reaction: Rituximab/CD20 complexes are removed from mantle cell lymphoma and chronic lymphocytic leukemia cells by THP-1 molecules. J Immunol. 2006;176:2600-2609.
    • (2006) J Immunol , vol.176 , pp. 2600-2609
    • Beum, P.V.1    Kennedy, A.D.2    Williams, M.E.3    Lindorfer, M.A.4    Taylor, R.P.5
  • 100
    • 0036023451 scopus 로고    scopus 로고
    • Intracellular accumulation of the anti-CD20 antibody 1F5 in B-lymphoma cells
    • Michel RB, Mattes MJ. Intracellular accumulation of the anti-CD20 antibody 1F5 in B-lymphoma cells. Clin Cancer Res. 2002;8:2701-2713.
    • (2002) Clin Cancer Res , vol.8 , pp. 2701-2713
    • Michel, R.B.1    Mattes, M.J.2
  • 102
    • 0020591822 scopus 로고
    • Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement
    • Hale G, Bright S, Chumbley G, Hoang T, Metcalf D, Munro AJ, Waldmann H. Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement. Blood. 1983;62:873-882.
    • (1983) Blood , vol.62 , pp. 873-882
    • Hale, G.1    Bright, S.2    Chumbley, G.3    Hoang, T.4    Metcalf, D.5    Munro, A.J.6    Waldmann, H.7
  • 103
    • 0025878925 scopus 로고
    • Characterization of the CAMPATH-1(CDw52) antigen: Biochemical analysis and cDNA cloning reveal an unusually small peptide backbone
    • Xia MQ, Tone M, Packman L, Hale G, Waldmann H. Characterization of the CAMPATH-1(CDw52) antigen: Biochemical analysis and cDNA cloning reveal an unusually small peptide backbone. Eur J Immunol. 1991;21:1677-1684.
    • (1991) Eur J Immunol , vol.21 , pp. 1677-1684
    • Xia, M.Q.1    Tone, M.2    Packman, L.3    Hale, G.4    Waldmann, H.5
  • 104
    • 40349114506 scopus 로고    scopus 로고
    • FDA drug approval summary: Alemtuzumab as single agent treatment for B cell CLL
    • Demko S, Summers J, Keegan P, Pazdur R. FDA drug approval summary: Alemtuzumab as single agent treatment for B cell CLL. Oncologist. 2008;13:167-174.
    • (2008) Oncologist , vol.13 , pp. 167-174
    • Demko, S.1    Summers, J.2    Keegan, P.3    Pazdur, R.4
  • 105
    • 0023820894 scopus 로고
    • Calicheamicin gamma 1: An antitumor antibiotic that cleaves double-stranded DNA site specifically
    • Zein N, Sinha AM, McGahren WJ, Ellestad GA. Calicheamicin gamma 1: An antitumor antibiotic that cleaves double-stranded DNA site specifically. Science. 1988;240:1198-1201.
    • (1988) Science , vol.240 , pp. 1198-1201
    • Zein, N.1    Sinha, A.M.2    McGahren, W.J.3    Ellestad, G.A.4
  • 111
    • 34347395733 scopus 로고    scopus 로고
    • Trastuzumab-mechanism of action and use in clinical practice
    • Hudis CA. Trastuzumab-mechanism of action and use in clinical practice. N Engl J Med. 2007;357:39-51.
    • (2007) N Engl J Med , vol.357 , pp. 39-51
    • Hudis, C.A.1
  • 112
    • 34447306848 scopus 로고    scopus 로고
    • Trastuzumab: Mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer
    • Valabrega G, Montemurro F, Aglietta M. Trastuzumab: Mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer. Ann Oncol. 2007;18:977-984.
    • (2007) Ann Oncol , vol.18 , pp. 977-984
    • Valabrega, G.1    Montemurro, F.2    Aglietta, M.3
  • 113
    • 0000212829 scopus 로고    scopus 로고
    • Overall survival (OS) advantage to simultaneous chemotherapy (CRx) plus the humanized anti-HER2 monoclonal antibody Herceptin (H) in HER2-overexpressing (HER2+) metastatic breast cancer (MBC)
    • Norton L, Slamon D, Leyland-Jones B. Overall survival (OS) advantage to simultaneous chemotherapy (CRx) plus the humanized anti-HER2 monoclonal antibody Herceptin (H) in HER2-overexpressing (HER2+) metastatic breast cancer (MBC). Proc Am Soc Clin Oncol. 1999;127a.
    • (1999) Proc Am Soc Clin Oncol , vol.127 A
    • Norton, L.1    Slamon, D.2    Leyland-Jones, B.3
  • 115
    • 0030856731 scopus 로고    scopus 로고
    • Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
    • Presta LG, Chen H, O'Connor SJ, Chisholm V, Meng YG, Krummen L, Winkler M, Ferrara N. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res. 1997;57:4593-4599.
    • (1997) Cancer Res , vol.57 , pp. 4593-4599
    • Presta, L.G.1    Chen, H.2    O'Connor, S.J.3    Chisholm, V.4    Meng, Y.G.5    Krummen, L.6    Winkler, M.7    Ferrara, N.8
  • 116
    • 2442621619 scopus 로고    scopus 로고
    • Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
    • Ferrara N, Hillan KJ, Gerber HP, Novotny W. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov. 2004;3:391-400.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 391-400
    • Ferrara, N.1    Hillan, K.J.2    Gerber, H.P.3    Novotny, W.4
  • 120
    • 77951258203 scopus 로고    scopus 로고
    • Bevacizumab as a treatment option in advanced renal cell carcinoma: An analysis and interpretation of clinical trial data
    • Mcdermott DF, George DJ. Bevacizumab as a treatment option in advanced renal cell carcinoma: An analysis and interpretation of clinical trial data. Cancer Treat Rev. 2010;36:216-223.
    • (2010) Cancer Treat Rev , vol.36 , pp. 216-223
    • Mcdermott, D.F.1    George, D.J.2
  • 121
    • 0031800885 scopus 로고    scopus 로고
    • EGF,TGF-alpha, and EGF-R in human colorectal adenocarcinoma
    • Messa C, Russo F, Caruso MG, DiLeo A. EGF, TGF-alpha, and EGF-R in human colorectal adenocarcinoma. Acta Oncol. 1998;37:285-289.
    • (1998) Acta Oncol , vol.37 , pp. 285-289
    • Messa, C.1    Russo, F.2    Caruso, M.G.3    DiLeo, A.4
  • 122
    • 2142641698 scopus 로고    scopus 로고
    • Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
    • Saltz LB, Meropol NJ, Loehrer PJ, Sr., Needle MN, Kopit J, Mayer RJ. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol. 2004;22:1201-1208.
    • (2004) J Clin Oncol , vol.22 , pp. 1201-1208
    • Saltz, L.B.1    Meropol, N.J.2    Loehrer Sr, P.J.3    Needle, M.N.4    Kopit, J.5    Mayer, R.J.6
  • 124
    • 13844250537 scopus 로고    scopus 로고
    • The epidermal growth factor receptor as a target for colorectal cancer therapy
    • Lockhart C, Berlin JD. The epidermal growth factor receptor as a target for colorectal cancer therapy. Semin Oncol. 2005;32:52-60.
    • (2005) Semin Oncol , vol.32 , pp. 52-60
    • Lockhart, C.1    Berlin, J.D.2
  • 125
    • 0034779291 scopus 로고    scopus 로고
    • The EGFR as a target for anticancer therapy-Focus on cetuximab
    • Baselga J. The EGFR as a target for anticancer therapy-Focus on cetuximab. Eur J Cancer. 2001;37:S16-S22.
    • (2001) Eur J Cancer , vol.37
    • Baselga, J.1
  • 126
    • 0035117355 scopus 로고    scopus 로고
    • Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy
    • Yang XD, Jia XC, Corvalan JR, Wang P, Davis CG. Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy. Crit Rev Oncol Hematol. 2001;38:17-23.
    • (2001) Crit Rev Oncol Hematol , vol.38 , pp. 17-23
    • Yang, X.D.1    Jia, X.C.2    Corvalan, J.R.3    Wang, P.4    Davis, C.G.5
  • 128
    • 0028283407 scopus 로고
    • Gene therapy for metabolic disorders
    • Kay MA, Woo SL. Gene therapy for metabolic disorders. Trends Genet. 1994;10:253-257.
    • (1994) Trends Genet , vol.10 , pp. 253-257
    • Kay, M.A.1    Woo, S.L.2
  • 129
    • 0038745599 scopus 로고    scopus 로고
    • Progress and problems with the use of viral vectors for gene therapy
    • Thomas CE, Ehrhardt A, Kay MA. Progress and problems with the use of viral vectors for gene therapy. Nat Rev Genet. 2003;4:346-358.
    • (2003) Nat Rev Genet , vol.4 , pp. 346-358
    • Thomas, C.E.1    Ehrhardt, A.2    Kay, M.A.3
  • 131
    • 0037215367 scopus 로고    scopus 로고
    • Dosimetric and technical considerations for interstitial adenoviral gene therapy as applied to prostate cancer
    • Li S, Simmons J, Detorie N, O'Rourke B, Hamper U, DeWeese TL. Dosimetric and technical considerations for interstitial adenoviral gene therapy as applied to prostate cancer. Int J Radiat Oncol Biol Phys. 2003;55:204-214.
    • (2003) Int J Radiat Oncol Biol Phys , vol.55 , pp. 204-214
    • Li, S.1    Simmons, J.2    Detorie, N.3    O'Rourke, B.4    Hamper, U.5    DeWeese, T.L.6
  • 133
    • 0030928619 scopus 로고    scopus 로고
    • Gene therapy-promises, problems and prospects
    • Verma IM, Somia N. Gene therapy-promises, problems and prospects. Nature (London). 1997;389:239-242.
    • (1997) Nature (London) , vol.389 , pp. 239-242
    • Verma, I.M.1    Somia, N.2
  • 135
    • 0026472495 scopus 로고
    • Retroviral gene transfer induced constitutive expression of interleukin-2 or interferon-gamma in irradiated human melanoma cells
    • Gansbacher B, Zier K, Cronin K, Hantzopoulos PA, Bouchard B, Houghton A, Gliboa E, Golde D. Retroviral gene transfer induced constitutive expression of interleukin-2 or interferon-gamma in irradiated human melanoma cells. Blood. 1992;80:2817-2825.
    • (1992) Blood , vol.80 , pp. 2817-2825
    • Gansbacher, B.1    Zier, K.2    Cronin, K.3    Hantzopoulos, P.A.4    Bouchard, B.5    Houghton, A.6    Gliboa, E.7    Golde, D.8
  • 138
    • 11144248909 scopus 로고    scopus 로고
    • The innate immune response to adenovirus vectors
    • Muruve DA. The innate immune response to adenovirus vectors. Hum Gene Ther. 2004;15:1157-1166.
    • (2004) Hum Gene Ther , vol.15 , pp. 1157-1166
    • Muruve, D.A.1
  • 139
    • 33749367953 scopus 로고    scopus 로고
    • Gene therapy for cancer treatment: Past, present and future
    • Cross D, Burmester JK. Gene therapy for cancer treatment: Past, present and future. Clin Med Res. 2006;3:218-227.
    • (2006) Clin Med Res , vol.3 , pp. 218-227
    • Cross, D.1    Burmester, J.K.2
  • 140
    • 0036227368 scopus 로고    scopus 로고
    • Development of safe and efficient novel nonviral gene transfer using ultrasound: Enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle
    • Taniyama Y, Tachibana K, Hiraoka K, Aoki M, Yamamoto S, Matsumoto K, Nakamura T, Ogihara T, Kaneda Y, Morishita R. Development of safe and efficient novel nonviral gene transfer using ultrasound: Enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle. Gene Ther. 2002;9:372-380.
    • (2002) Gene Ther , vol.9 , pp. 372-380
    • Taniyama, Y.1    Tachibana, K.2    Hiraoka, K.3    Aoki, M.4    Yamamoto, S.5    Matsumoto, K.6    Nakamura, T.7    Ogihara, T.8    Kaneda, Y.9    Morishita, R.10
  • 142
    • 0033005285 scopus 로고    scopus 로고
    • Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors
    • Li S, Wu SP, Whitmore M, Loeffert EJ, Wng L, Watkins SC, Pitt BR, Huang L. Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors. Am J Physiol. 1999;276:L796-L804.
    • (1999) Am J Physiol , vol.276
    • Li, S.1    Wu, S.P.2    Whitmore, M.3    Loeffert, E.J.4    Wng, L.5    Watkins, S.C.6    Pitt, B.R.7    Huang, L.8
  • 143
    • 0029121499 scopus 로고
    • Construction, purification and functional reconstitution on tumor cells of glycolipid-anchored human B7-1 (CD80)
    • McHugh RS, Ahmed SN, Wang Y-C, Sell KW, Selvaraj P. Construction, purification and functional reconstitution on tumor cells of glycolipid-anchored human B7-1 (CD80). Proc Natl Acad Sci USA. 1995;92:8059-8063.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8059-8063
    • McHugh, R.S.1    Ahmed, S.N.2    Wang, Y.-C.3    Sell, K.W.4    Selvaraj, P.5
  • 144
    • 0029111505 scopus 로고
    • Purification and optimization of functional reconstitution on the surface of leukemic cell lines of GPI-anchored Fcγreceptor III
    • Nagarajan S, Anderson M, Ahmed SN, Sell KW, Selvaraj P. Purification and optimization of functional reconstitution on the surface of leukemic cell lines of GPI-anchored Fcγreceptor III. J Immunol Methods. 1995;184:241-251.
    • (1995) J Immunol Methods , vol.184 , pp. 241-251
    • Nagarajan, S.1    Anderson, M.2    Ahmed, S.N.3    Sell, K.W.4    Selvaraj, P.5
  • 145
    • 0344817850 scopus 로고
    • Construction, purification, and functional reconstitution on tumor cells of a glycolipid anchored B7-1 molecule: A novel alternative to gene transfection in human immunotherapy
    • McHugh RS, Ahmed SN, Wang Y-C, Sell KW, Selvaraj P. Construction, purification, and functional reconstitution on tumor cells of a glycolipid anchored B7-1 molecule: A novel alternative to gene transfection in human immunotherapy. Proc Am Assoc Cancer Res. 1995;36:494-
    • (1995) Proc Am Assoc Cancer Res , vol.36 , pp. 494
    • McHugh, R.S.1    Ahmed, S.N.2    Wang, Y.-C.3    Sell, K.W.4    Selvaraj, P.5
  • 146
    • 0033562996 scopus 로고    scopus 로고
    • Protein transfer of glycosylphosphatidylinositol-B7-1 into tumor cell membranes: A novel approach to tumor immunotherapy
    • McHugh RS, Nagarajan S, Wang YC, Sell KW, Selvaraj P. Protein transfer of glycosylphosphatidylinositol-B7-1 into tumor cell membranes: A novel approach to tumor immunotherapy. Cancer Res. 1999;59:2433-2437.
    • (1999) Cancer Res , vol.59 , pp. 2433-2437
    • McHugh, R.S.1    Nagarajan, S.2    Wang, Y.C.3    Sell, K.W.4    Selvaraj, P.5
  • 149
    • 0023578991 scopus 로고
    • Deficiency of lymphocyte function associated antigen-3 (LFA-3) in paroxysmal nocturnal hemoglobinuria: Functional correlates and evidence for a phosphatidylinositol membrane anchor
    • Selvaraj P, Dustin ML, Silber R, Low MG, Springer TA. Deficiency of lymphocyte function associated antigen-3 (LFA-3) in paroxysmal nocturnal hemoglobinuria: Functional correlates and evidence for a phosphatidylinositol membrane anchor. J Exp Med. 1987;166:1011-1025.
    • (1987) J Exp Med , vol.166 , pp. 1011-1025
    • Selvaraj, P.1    Dustin, M.L.2    Silber, R.3    Low, M.G.4    Springer, T.A.5
  • 150
    • 0024282583 scopus 로고
    • The major Fc receptor in blood has a phosphatidylinositol anchor and is deficient in paroxysmal nocturnal hemoglobinuria
    • Selvaraj P, Rosse WF, Silber R, Springer TA. The major Fc receptor in blood has a phosphatidylinositol anchor and is deficient in paroxysmal nocturnal hemoglobinuria. Nature. 1988;333:565-567.
    • (1988) Nature , vol.333 , pp. 565-567
    • Selvaraj, P.1    Rosse, W.F.2    Silber, R.3    Springer, T.A.4
  • 151
    • 0028981209 scopus 로고
    • How glycosyl phosphatidylinositol-anchored membrane proteins are made
    • Udenfriend S, Kodukula K. How glycosyl phosphatidylinositol-anchored membrane proteins are made. Annu Rev Biochem. 1995;64:563-591.
    • (1995) Annu Rev Biochem , vol.64 , pp. 563-591
    • Udenfriend, S.1    Kodukula, K.2
  • 152
    • 77951895530 scopus 로고    scopus 로고
    • Structural remodeling of GPI anchors during biosynthesis and after attachment to proteins
    • Fujita M, Kinoshita T. Structural remodeling of GPI anchors during biosynthesis and after attachment to proteins. FEBS Lett. 2010;584:1670-1677.
    • (2010) FEBS Lett , vol.584 , pp. 1670-1677
    • Fujita, M.1    Kinoshita, T.2
  • 153
    • 0023654822 scopus 로고
    • Biochemistry of the glycosyl-phosphatidylinositol membrane protein anchors
    • Low MG. Biochemistry of the glycosyl-phosphatidylinositol membrane protein anchors. Biochem J. 1987;244:1-13.
    • (1987) Biochem J , vol.244 , pp. 1-13
    • Low, M.G.1
  • 154
    • 0025203675 scopus 로고
    • Glycolipid anchoring of plasma membrane proteins
    • Cross GAM. Glycolipid anchoring of plasma membrane proteins. Annu Rev Cell Biol. 1990;6:1-39.
    • (1990) Annu Rev Cell Biol , vol.6 , pp. 1-39
    • Cross, G.A.M.1
  • 155
    • 46849102138 scopus 로고    scopus 로고
    • The glycosylphosphatidylinositol anchor: A complex membrane-anchoring structure for proteins
    • Paulick MG, Bertozzi CR. The glycosylphosphatidylinositol anchor: A complex membrane-anchoring structure for proteins. Biochemistry. 2008;47:6991-7000.
    • (2008) Biochemistry , vol.47 , pp. 6991-7000
    • Paulick, M.G.1    Bertozzi, C.R.2
  • 157
    • 0021713655 scopus 로고
    • Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes
    • Medof ME, Kinoshita T, Nussenzweig V. Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes. J Exp Med. 1984;160:1558-1563.
    • (1984) J Exp Med , vol.160 , pp. 1558-1563
    • Medof, M.E.1    Kinoshita, T.2    Nussenzweig, V.3
  • 158
    • 25744455393 scopus 로고
    • Reconstitution of CD16 expression on nucleated cells using purified CD16
    • Nagarajan S, Selvaraj P. Reconstitution of CD16 expression on nucleated cells using purified CD16. FASEB J. 1991;5:A1718-
    • (1991) FASEB J , vol.5
    • Nagarajan, S.1    Selvaraj, P.2
  • 159
    • 0028802579 scopus 로고
    • Glycosylphosphatidylinositol-modified murine B7-1 and B7-2 retain costimulator function
    • Brunschwig EB, Levine E, Trefzer U, Tykocinski ML. Glycosylphosphatidylinositol-modified murine B7-1 and B7-2 retain costimulator function. J Immunol. 1995;155:5498-5505.
    • (1995) J Immunol , vol.155 , pp. 5498-5505
    • Brunschwig, E.B.1    Levine, E.2    Trefzer, U.3    Tykocinski, M.L.4
  • 160
    • 0030004824 scopus 로고    scopus 로고
    • Induction of autologous tumor-specific cytotoxic T-lymphocyte activity against a human renal carcinoma cell line by B7-1 (CD80) costimulation
    • Wang YC, Zhu L, McHugh R, Graham SD, Jr., Hillyer C, Dillehay D, Sell KW, Selvaraj P. Induction of autologous tumor-specific cytotoxic T-lymphocyte activity against a human renal carcinoma cell line by B7-1 (CD80) costimulation. J Immunother. 1996;19:1-8.
    • (1996) J Immunother , vol.19 , pp. 1-8
    • Wang, Y.C.1    Zhu, L.2    McHugh, R.3    Graham Jr., S.D.4    Hillyer, C.5    Dillehay, D.6    Sell, K.W.7    Selvaraj, P.8
  • 161
    • 0037093038 scopus 로고    scopus 로고
    • Glycolipid-anchored IL-12 expressed on tumor cell surface induces antitumor immune response
    • Nagarajan S, Selvaraj P. Glycolipid-anchored IL-12 expressed on tumor cell surface induces antitumor immune response. Cancer Res. 2002;62:2869-2874.
    • (2002) Cancer Res , vol.62 , pp. 2869-2874
    • Nagarajan, S.1    Selvaraj, P.2
  • 164
    • 0027284230 scopus 로고
    • Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation
    • Gimmi CD, Freeman GJ, Gribben JG, Gray G, Nadler LM. Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation. Proc Natl Acad Sci USA. 1993;90:6586-6590.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6586-6590
    • Gimmi, C.D.1    Freeman, G.J.2    Gribben, J.G.3    Gray, G.4    Nadler, L.M.5
  • 165
    • 0027211058 scopus 로고
    • Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules
    • Baskar S, Ostrand Rosenberg S, Nabavi N, Nadler LM, Freeman GJ, Glimcher LH. Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules. Proc Natl Acad Sci USA. 1993;90:5687-5690.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5687-5690
    • Baskar, S.1    Ostrand Rosenberg, S.2    Nabavi, N.3    Nadler, L.M.4    Freeman, G.J.5    Glimcher, L.H.6
  • 166
    • 0036196662 scopus 로고    scopus 로고
    • GPI-anchoring of GM-CSF results in active membrane-bound and partially shed cytokine
    • Poloso NJ, Nagarajan S, Mejia-Oneta JM, Selvaraj P. GPI-anchoring of GM-CSF results in active membrane-bound and partially shed cytokine. Mol Immunol. 2002;38:803-816.
    • (2002) Mol Immunol , vol.38 , pp. 803-816
    • Poloso, N.J.1    Nagarajan, S.2    Mejia-Oneta, J.M.3    Selvaraj, P.4
  • 167
    • 0033948423 scopus 로고    scopus 로고
    • Induction of tumor-specific immunity in mice by immunization with reconstituted tumor membrane liposomes containing recombinant B7-2
    • Westerman LE, Sund SC, Selvaraj P, Jensen PE. Induction of tumor-specific immunity in mice by immunization with reconstituted tumor membrane liposomes containing recombinant B7-2. J Immunother. 2000;23:456-463.
    • (2000) J Immunother , vol.23 , pp. 456-463
    • Westerman, L.E.1    Sund, S.C.2    Selvaraj, P.3    Jensen, P.E.4
  • 168
    • 0036151027 scopus 로고    scopus 로고
    • ITAMs versus ITIMs: Striking a balance during cell regulation
    • Billadeau DD. ITAMs versus ITIMs: Striking a balance during cell regulation. J Clin Invest. 2002;109:161-168.
    • (2002) J Clin Invest , vol.109 , pp. 161-168
    • Billadeau, D.D.1
  • 169
    • 84867456806 scopus 로고    scopus 로고
    • Melanoma cells expressing membrane-anchored IL-2 and IL-12 induce effective antitumor immunity in the presence or absence of B7-1 costimulation
    • Shashidharamurthy R, Panchanathan R, Fiske ED, Tien L, Selvaraj P. Melanoma cells expressing membrane-anchored IL-2 and IL-12 induce effective antitumor immunity in the presence or absence of B7-1 costimulation. FASEB J. 2008;22:1078.21-
    • (2008) FASEB J , vol.22 , pp. 107821
    • Shashidharamurthy, R.1    Panchanathan, R.2    Fiske, E.D.3    Tien, L.4    Selvaraj, P.5
  • 170
    • 33344457223 scopus 로고    scopus 로고
    • Human tumor membrane vesicles modified to express glycolipid-anchored IL-12 by protein transfer induce T cell proliferation in vitro: A potential approach for local delivery of cytokines during vaccination
    • Nagarajan S, Selvaraj P. Human tumor membrane vesicles modified to express glycolipid-anchored IL-12 by protein transfer induce T cell proliferation in vitro: A potential approach for local delivery of cytokines during vaccination. Vaccine. 2006;24:2264-2274.
    • (2006) Vaccine , vol.24 , pp. 2264-2274
    • Nagarajan, S.1    Selvaraj, P.2


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