Human tumor membrane vesicles modified to express glycolipid-anchored IL-12 by protein transfer induce T cell proliferation in vitro: A potential approach for local delivery of cytokines during vaccination

Vaccine

Volumn 24, Issue 13, 2006, Pages 2264-2274

  Nagarajan, Shanmugam ^a,b   Selvaraj, Periasamy ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b U S DEPARTMENT OF AGRICULTURE   (United States)

Author keywords

GPI; IL 12; Membrane vesicles; Protein transfer; Tumor vaccine

Indexed keywords

B7 ANTIGEN; CD59 ANTIGEN; CYTOKINE; DISULFIDE; GAMMA INTERFERON; GLYCOLIPID; GLYCOSYLPHOSPHATIDYLINOSITOL; HETERODIMER; INTERLEUKIN 12; PROTEIN; PROTEIN SUBUNIT;

ANIMAL CELL; ARTICLE; CANCER IMMUNOTHERAPY; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG PURIFICATION; GENE THERAPY; HUMAN; HUMAN CELL; IMMUNOGENICITY; LYMPHOCYTE PROLIFERATION; MEMBRANE VESICLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN TRANSPORT; RAT; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TUMOR; TUMOR CELL LINE; VACCINATION;

ANIMALS; ANTIGENS, CD40; ANTIGENS, CD80; CANCER VACCINES; CELL MEMBRANE; CHO CELLS; CRICETINAE; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; INTERFERON TYPE II; INTERLEUKIN-12; LYMPHOCYTE ACTIVATION; MICE; T-LYMPHOCYTES; VACCINATION; VACCINES, SYNTHETIC;

EID: 33344457223     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.11.045     Document Type: Article

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