Anti-proliferative effects of tricyclodecan-9-yl-xanthogenate (D609) involve ceramide and cell cycle inhibition

Molecular Neurobiology

Volumn 45, Issue 3, 2012, Pages 455-464

  Gusain, Anchal ^a   Hatcher, James F ^a,c   Adibhatla, Rao Muralikrishna ^a,b,c   Wesley, Umadevi V ^a   Dempsey, Robert J ^a,c  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b University of Wisconsin Cardiovascular Research Center   (United States)

^c WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

Author keywords

Astrocytes; BrdU; Cell cycle; Ceramide; Flow cytometry; Macrophages; Microglia; p21; Sphingomyelin synthase

Indexed keywords

BRIDGED COMPOUND; BROXURIDINE; CASPASE 3; CERAMIDE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DIACYLGLYCEROL; SPHINGOMYELIN; THIOKETONE; TRICYCLODECANE 9 YL XANTHOGENATE; TRICYCLODECANE-9-YL-XANTHOGENATE;

ANIMAL; ARTICLE; CELL CYCLE; CELL CYCLE CHECKPOINT; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; METABOLISM; MOUSE; TIME;

ANIMALS; BRIDGED COMPOUNDS; BROMODEOXYURIDINE; CASPASE 3; CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CERAMIDES; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DIGLYCERIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; MICE; SPHINGOMYELINS; THIONES; TIME FACTORS;

EID: 84867445472     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-012-8254-0     Document Type: Article

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