Mitochondrial dysfunction in insulin resistance: Differential contributions of chronic insulin and saturated fatty acid exposure in muscle cells

Bioscience Reports

Volumn 32, Issue 5, 2012, Pages 465-478

  Yang, Chenjing ^a   Aye, Cho Cho ^a   Li, Xiaoxin ^a   Diaz Ramos, Angels ^b   Zorzano, Antonio ^b   Mora, Silvia ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Fatty acid; Insulin; Insulin resistance; Membrane potential; Mitochondrion; Myocyte; Peroxisome proliferator activated receptor co activator 1

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOCHROME C OXIDASE; INSULIN; MITOCHONDRIAL ELECTRON CHAIN COMPLEX PROTEIN; MITOCHONDRIAL PROTEIN; MITOFUSIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SATURATED FATTY ACID; STRESS ACTIVATED PROTEIN KINASE; SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; GLYCOLYSIS; IN VITRO STUDY; INSULIN RESISTANCE; MITOCHONDRIAL GENE; MITOCHONDRIAL MEMBRANE POTENTIAL; MUSCLE CELL; MYOTUBE; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELLS, CULTURED; FATTY ACIDS; GENE EXPRESSION REGULATION; GTP PHOSPHOHYDROLASES; INSULIN; INSULIN RESISTANCE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PALMITIC ACID; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION; UNCOUPLING AGENTS;

EID: 84867393052     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20120034     Document Type: Article

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