메뉴 건너뛰기




Volumn 1269, Issue 1, 2012, Pages 84-91

Thymosin β4 and cardiac protection: Implication in inflammation and fibrosis

Author keywords

Antioxidative genes; Cardiac fibrosis; NF B; Thymosin 4

Indexed keywords

CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN; INTEGRIN LINK KINASE; PHOSPHOTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; THYMOSIN BETA4; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 84867380703     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2012.06752.x     Document Type: Article
Times cited : (31)

References (67)
  • 1
    • 0042307332 scopus 로고    scopus 로고
    • Thymosin beta 4 interactions
    • Bubb, M.R. 2003. Thymosin beta 4 interactions. VitamHorm 66: 297-316.
    • (2003) VitamHorm , vol.66 , pp. 297-316
    • Bubb, M.R.1
  • 2
    • 0030926245 scopus 로고    scopus 로고
    • Thymosin beta 4 stimulates directional migration of human umbilical vein endothelial cells
    • Malinda, K.M., A.L. Goldstein and H.K. Kleinman 1997. Thymosin beta 4 stimulates directional migration of human umbilical vein endothelial cells. Faseb J. 11: 474-481.
    • (1997) Faseb J. , vol.11 , pp. 474-481
    • Malinda, K.M.1    Goldstein, A.L.2    Kleinman, H.K.3
  • 3
    • 24344500165 scopus 로고    scopus 로고
    • Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues
    • Goldstein, A.L., E. Hannappel & H.K. Kleinman 2005. Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues. Trends Mol. Med. 11: 421-429.
    • (2005) Trends Mol. Med. , vol.11 , pp. 421-429
    • Goldstein, A.L.1    Hannappel, E.2    Kleinman, H.K.3
  • 4
    • 77951778555 scopus 로고    scopus 로고
    • Thymosin beta4: a key factor for protective effects of eEPCs in acute and chronic ischemia
    • Hinkel, R. et al 2010. Thymosin beta4: a key factor for protective effects of eEPCs in acute and chronic ischemia. Ann. N. Y. Acad. Sci. 1194: 105-111.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1194 , pp. 105-111
    • Hinkel, R.1
  • 5
    • 0642303652 scopus 로고    scopus 로고
    • The actin binding site on thymosin beta4 promotes angiogenesis
    • Philp, D. et al 2003. The actin binding site on thymosin beta4 promotes angiogenesis. Faseb. J. 17: 2103-2105.
    • (2003) Faseb. J. , vol.17 , pp. 2103-2105
    • Philp, D.1
  • 6
    • 0342576715 scopus 로고
    • Complete amino acid sequence of bovine thymosin beta 4: a thymic hormone that induces terminal deoxynucleotidyltransferase activity in thymocyte populations
    • Low, T.L., S.K. Hu & A.L. Goldstein 1981. Complete amino acid sequence of bovine thymosin beta 4: a thymic hormone that induces terminal deoxynucleotidyltransferase activity in thymocyte populations. Proc. Natl. Acad. Sci. U. S. A. 78: 1162-1166.
    • (1981) Proc. Natl. Acad. Sci. U. S. A. , vol.78 , pp. 1162-1166
    • Low, T.L.1    Hu, S.K.2    Goldstein, A.L.3
  • 7
    • 33646172942 scopus 로고    scopus 로고
    • Thymosin beta4 induces a conformational change in actin monomers
    • Dedova, I.V. et al 2006. Thymosin beta4 induces a conformational change in actin monomers. Biophys. J. 90: 985-992.
    • (2006) Biophys. J. , vol.90 , pp. 985-992
    • Dedova, I.V.1
  • 8
    • 35348953071 scopus 로고    scopus 로고
    • Contributions from all over: widely distributed residues in thymosin beta-4 affect the kinetics and stability of actin binding
    • Au, J.K., E.M. De La Cruz & D. Safer 2007. Contributions from all over: widely distributed residues in thymosin beta-4 affect the kinetics and stability of actin binding. Ann. N. Y. Acad. Sci. 1112: 38-44.
    • (2007) Ann. N. Y. Acad. Sci. , vol.1112 , pp. 38-44
    • Au, J.K.1    De La Cruz, E.M.2    Safer, D.3
  • 9
    • 84055193007 scopus 로고    scopus 로고
    • Thymosin beta4: a multi-functional regenerative peptide. Basic properties and clinical applications
    • Goldstein, A.L. et al 2012. Thymosin beta4: a multi-functional regenerative peptide. Basic properties and clinical applications. Expert Opin. Biol. Ther. 12: 37-51.
    • (2012) Expert Opin. Biol. Ther. , vol.12 , pp. 37-51
    • Goldstein, A.L.1
  • 10
    • 77951788169 scopus 로고    scopus 로고
    • Thymosin beta4 enhances repair by organizing connective tissue and preventing the appearance of myofibroblasts
    • Ehrlich, H.P. & S.W. Hazard, 3rd. 2010. Thymosin beta4 enhances repair by organizing connective tissue and preventing the appearance of myofibroblasts. Ann. N. Y. Acad. Sci. 1194: 118-124.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1194 , pp. 118-124
    • Ehrlich, H.P.1    Hazard 3rd, S.W.2
  • 11
    • 33746919929 scopus 로고    scopus 로고
    • Thymosin [beta]4 inhibits benzalkonium chloride-mediated apoptosis in corneal and conjunctival epithelial cells in vitro
    • Sosne, G. et al 2006. Thymosin [beta]4 inhibits benzalkonium chloride-mediated apoptosis in corneal and conjunctival epithelial cells in vitro. Exp. Eye Res. 83: 502-507.
    • (2006) Exp. Eye Res. , vol.83 , pp. 502-507
    • Sosne, G.1
  • 12
    • 77951845671 scopus 로고    scopus 로고
    • Thymosin beta4 and corneal wound healing: visions of the future
    • Sosne, G. et al 2010. Thymosin beta4 and corneal wound healing: visions of the future. Ann. N. Y. Acad. Sci. 1194: 190-198.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1194 , pp. 190-198
    • Sosne, G.1
  • 13
    • 77951772232 scopus 로고    scopus 로고
    • Thymosin beta 4: a novel corneal wound healing and anti-inflammatory agent
    • Sosne, G., P. Qiu & M. Kurpakus-Wheater 2007. Thymosin beta 4: a novel corneal wound healing and anti-inflammatory agent. Clin. Ophthalmol. 1: 201-207.
    • (2007) Clin. Ophthalmol. , vol.1 , pp. 201-207
    • Sosne, G.1    Qiu, P.2    Kurpakus-Wheater, M.3
  • 14
    • 9644281738 scopus 로고    scopus 로고
    • Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair
    • Bock-Marquette, I. et al 2004. Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature 432: 466-472.
    • (2004) Nature , vol.432 , pp. 466-472
    • Bock-Marquette, I.1
  • 15
    • 33846243239 scopus 로고    scopus 로고
    • Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization
    • Smart, N. et al 2007. Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization. Nature 445: 177-182.
    • (2007) Nature , vol.445 , pp. 177-182
    • Smart, N.1
  • 16
    • 77951782307 scopus 로고    scopus 로고
    • Thymosin beta4 facilitates epicardial neovascularization of the injured adult heart
    • Smart, N. et al 2010. Thymosin beta4 facilitates epicardial neovascularization of the injured adult heart. Ann. N. Y. Acad. Sci. 1194: 97-104.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1194 , pp. 97-104
    • Smart, N.1
  • 17
    • 84856468064 scopus 로고    scopus 로고
    • Thymosin beta4 protein therapy for cardiac repair
    • Dube, K.N. et al 2012. Thymosin beta4 protein therapy for cardiac repair. Curr. Pharm. Des. 18: 799-806.
    • (2012) Curr. Pharm. Des. , vol.18 , pp. 799-806
    • Dube, K.N.1
  • 18
    • 58749089339 scopus 로고    scopus 로고
    • Embryonic endothelial progenitor cell-mediated cardioprotection requires Thymosin beta4
    • Kupatt, C., I. Bock-Marquette & P. Boekstegers 2008. Embryonic endothelial progenitor cell-mediated cardioprotection requires Thymosin beta4. Trends Cardiovasc. Med. 18: 205-210.
    • (2008) Trends Cardiovasc. Med. , vol.18 , pp. 205-210
    • Kupatt, C.1    Bock-Marquette, I.2    Boekstegers, P.3
  • 19
    • 67649206633 scopus 로고    scopus 로고
    • Thymosin beta4 induces endothelial progenitor cell migration via PI3K/Akt/eNOS signal transduction pathway
    • Qiu, F.Y. et al 2009. Thymosin beta4 induces endothelial progenitor cell migration via PI3K/Akt/eNOS signal transduction pathway. J. Cardiovasc. Pharmacol. 53: 209-214.
    • (2009) J. Cardiovasc. Pharmacol. , vol.53 , pp. 209-214
    • Qiu, F.Y.1
  • 20
    • 63549141609 scopus 로고    scopus 로고
    • Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo
    • Bock-Marquette, I. et al 2009. Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo. J. Mol. Cell Cardiol. 46: 728-738.
    • (2009) J. Mol. Cell Cardiol. , vol.46 , pp. 728-738
    • Bock-Marquette, I.1
  • 21
    • 0032949682 scopus 로고    scopus 로고
    • Molecular mechanisms of myocardial remodeling
    • Swynghedauw, B. 1999. Molecular mechanisms of myocardial remodeling. Physiol. Rev. 79: 215-262.
    • (1999) Physiol. Rev. , vol.79 , pp. 215-262
    • Swynghedauw, B.1
  • 22
    • 80054991414 scopus 로고    scopus 로고
    • New targets to treat the structural remodeling of the myocardium
    • Gonzalez, A. et al 2011. New targets to treat the structural remodeling of the myocardium. J. Am. Coll. Cardiol. 58: 1833-1843.
    • (2011) J. Am. Coll. Cardiol. , vol.58 , pp. 1833-1843
    • Gonzalez, A.1
  • 23
    • 35349031022 scopus 로고    scopus 로고
    • Thymosin beta4 is cardioprotective after myocardial infarction
    • Srivastava, D. et al 2007. Thymosin beta4 is cardioprotective after myocardial infarction. Ann. N. Y. Acad. Sci. 1112: 161-170.
    • (2007) Ann. N. Y. Acad. Sci. , vol.1112 , pp. 161-170
    • Srivastava, D.1
  • 24
    • 77951804946 scopus 로고    scopus 로고
    • Thymosin beta4 and cardiac repair
    • Shrivastava, S. et al 2010. Thymosin beta4 and cardiac repair. Ann. N. Y. Acad. Sci. 1194: 87-96.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1194 , pp. 87-96
    • Shrivastava, S.1
  • 25
    • 35348973665 scopus 로고    scopus 로고
    • Development of thymosin beta4 for treatment of patients with ischemic heart disease
    • Crockford, D. 2007. Development of thymosin beta4 for treatment of patients with ischemic heart disease. Ann. N. Y. Acad. Sci. 1112: 385-395.
    • (2007) Ann. N. Y. Acad. Sci. , vol.1112 , pp. 385-395
    • Crockford, D.1
  • 26
    • 84861159240 scopus 로고    scopus 로고
    • Thymosin beta4 levels after successful primary percutaneous coronary intervention for acute myocardial infarction
    • Yesilay, A.B. et al 2011. Thymosin beta4 levels after successful primary percutaneous coronary intervention for acute myocardial infarction. Turk KardiyolojiDernegiarsivi: Turk KardiyolojiDernegininyayinorganidir. 39: 654-660.
    • (2011) Turk KardiyolojiDernegiarsivi: Turk KardiyolojiDernegininyayinorganidir. , vol.39 , pp. 654-660
    • Yesilay, A.B.1
  • 27
    • 33751226584 scopus 로고    scopus 로고
    • Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice
    • Lu, H. et al 2006. Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice. Circulation 114: 2271-2279.
    • (2006) Circulation , vol.114 , pp. 2271-2279
    • Lu, H.1
  • 28
    • 33748278519 scopus 로고    scopus 로고
    • Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure
    • White, D.E. et al 2006. Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure. Genes Dev. 20: 2355-2360.
    • (2006) Genes Dev. , vol.20 , pp. 2355-2360
    • White, D.E.1
  • 29
    • 34249660635 scopus 로고    scopus 로고
    • Integrin-linked kinase at the heart of cardiac contractility, repair, and disease
    • Hannigan, G.E., J.G. Coles & S. Dedhar 2007. Integrin-linked kinase at the heart of cardiac contractility, repair, and disease. Circ. Res. 100: 1408-1414.
    • (2007) Circ. Res. , vol.100 , pp. 1408-1414
    • Hannigan, G.E.1    Coles, J.G.2    Dedhar, S.3
  • 30
    • 34548407064 scopus 로고    scopus 로고
    • Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells
    • Knoll, R. et al 2007. Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells. Circulation 116: 515-525.
    • (2007) Circulation , vol.116 , pp. 515-525
    • Knoll, R.1
  • 31
    • 70349334413 scopus 로고    scopus 로고
    • Increased expression of integrin-linked kinase attenuates left ventricular remodeling and improves cardiac function after myocardial infarction
    • Ding, L. et al 2009. Increased expression of integrin-linked kinase attenuates left ventricular remodeling and improves cardiac function after myocardial infarction. Circulation 120: 764-773.
    • (2009) Circulation , vol.120 , pp. 764-773
    • Ding, L.1
  • 32
    • 84856918850 scopus 로고    scopus 로고
    • Increased expression of integrin-linked kinase improves cardiac function and decreases mortality in dilated cardiomyopathy model of rats
    • Gu, R. et al 2012. Increased expression of integrin-linked kinase improves cardiac function and decreases mortality in dilated cardiomyopathy model of rats. PLoS One 7: e31279.
    • (2012) PLoS One , vol.7
    • Gu, R.1
  • 33
    • 61449220945 scopus 로고    scopus 로고
    • Genetic and cell biological analysis of integrin outside-in signaling
    • Legate, K.R., S.A. Wickstrom & R. Fassler 2009. Genetic and cell biological analysis of integrin outside-in signaling. Genes. Dev. 23: 397-418.
    • (2009) Genes. Dev. , vol.23 , pp. 397-418
    • Legate, K.R.1    Wickstrom, S.A.2    Fassler, R.3
  • 34
    • 0345803932 scopus 로고    scopus 로고
    • PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival
    • Fukuda, T. et al 2003. PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival. J. Biol. Chem. 278: 51324-51333.
    • (2003) J. Biol. Chem. , vol.278 , pp. 51324-51333
    • Fukuda, T.1
  • 35
    • 0037417416 scopus 로고    scopus 로고
    • CH-ILKBP regulates cell survival by facilitating the membrane translocation of protein kinase B/Akt
    • Fukuda, T. et al 2003. CH-ILKBP regulates cell survival by facilitating the membrane translocation of protein kinase B/Akt. J. Cell Biol. 160: 1001-1008.
    • (2003) J. Cell Biol. , vol.160 , pp. 1001-1008
    • Fukuda, T.1
  • 36
    • 79956286435 scopus 로고    scopus 로고
    • Significance of thymosin beta4 and implication of PINCH-1-ILK-alpha-Parvin (PIP) complex in human dilated cardiomyopathy
    • Sopko, N. et al 2011. Significance of thymosin beta4 and implication of PINCH-1-ILK-alpha-Parvin (PIP) complex in human dilated cardiomyopathy. PLoS One 6: e20184.
    • (2011) PLoS One , vol.6
    • Sopko, N.1
  • 37
    • 44049106474 scopus 로고    scopus 로고
    • Thymosin beta4 is an essential paracrine factor of embryonic endothelial progenitor cell-mediated cardioprotection
    • Hinkel, R. et al 2008. Thymosin beta4 is an essential paracrine factor of embryonic endothelial progenitor cell-mediated cardioprotection. Circulation 117: 2232-2240.
    • (2008) Circulation , vol.117 , pp. 2232-2240
    • Hinkel, R.1
  • 38
    • 84055214880 scopus 로고    scopus 로고
    • Thymosin beta 4 treatment after myocardial infarction does not reprogram epicardial cells into cardiomyocytes
    • Zhou, B. et al 2012. Thymosin beta 4 treatment after myocardial infarction does not reprogram epicardial cells into cardiomyocytes. J. Mol. Cell Cardiol. 52: 43-47.
    • (2012) J. Mol. Cell Cardiol. , vol.52 , pp. 43-47
    • Zhou, B.1
  • 40
    • 84856756039 scopus 로고    scopus 로고
    • Thymosin beta 4 is dispensable for murine cardiac development and function
    • Banerjee, I. et al 2012. Thymosin beta 4 is dispensable for murine cardiac development and function. Circ. Res. 110: 456-464.
    • (2012) Circ. Res. , vol.110 , pp. 456-464
    • Banerjee, I.1
  • 41
    • 34548746306 scopus 로고    scopus 로고
    • Myocardial reperfusion injury
    • Yellon, D.M. & D.J. Hausenloy 2007. Myocardial reperfusion injury. N. Engl. J. Med. 357: 1121-1135.
    • (2007) N. Engl. J. Med. , vol.357 , pp. 1121-1135
    • Yellon, D.M.1    Hausenloy, D.J.2
  • 42
    • 80155198133 scopus 로고    scopus 로고
    • The role of monocytes and inflammation in the pathophysiology of heart failure
    • Wrigley, B.J., G.Y. Lip & E. Shantsila 2011. The role of monocytes and inflammation in the pathophysiology of heart failure. Eur. J. Heart Fail. 13: 1161-1171.
    • (2011) Eur. J. Heart Fail. , vol.13 , pp. 1161-1171
    • Wrigley, B.J.1    Lip, G.Y.2    Shantsila, E.3
  • 43
    • 0037632133 scopus 로고    scopus 로고
    • Thymosinbeta(4) reduces lethality and down-regulates inflammatory mediators in endotoxin-induced septic shock
    • Badamchian, M. et al 2003. Thymosinbeta(4) reduces lethality and down-regulates inflammatory mediators in endotoxin-induced septic shock. Int. Immunopharmacol. 3: 1225-1233.
    • (2003) Int. Immunopharmacol. , vol.3 , pp. 1225-1233
    • Badamchian, M.1
  • 44
    • 33750989327 scopus 로고    scopus 로고
    • Therapeutic potential of thymosin-beta4 and its derivative N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) in cardiac healing after infarction
    • Cavasin, M.A. 2006. Therapeutic potential of thymosin-beta4 and its derivative N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) in cardiac healing after infarction. Am. J. Cardiovasc. Drugs 6: 305-311.
    • (2006) Am. J. Cardiovasc. Drugs , vol.6 , pp. 305-311
    • Cavasin, M.A.1
  • 45
    • 0037954136 scopus 로고    scopus 로고
    • Anti-inflammatory effects in the skin of thymosin-beta4 splice-variants
    • Girardi, M. et al 2003. Anti-inflammatory effects in the skin of thymosin-beta4 splice-variants. Immunology 109: 1-7.
    • (2003) Immunology , vol.109 , pp. 1-7
    • Girardi, M.1
  • 46
    • 0036349917 scopus 로고    scopus 로고
    • Thymosin beta 4 promotes corneal wound healing and decreases inflammation in vivo following alkali injury
    • Sosne, G. et al 2002. Thymosin beta 4 promotes corneal wound healing and decreases inflammation in vivo following alkali injury. Exp. Eye Res. 74: 293-299.
    • (2002) Exp. Eye Res. , vol.74 , pp. 293-299
    • Sosne, G.1
  • 47
    • 23244447079 scopus 로고    scopus 로고
    • Thymosin-beta4 modulates corneal matrix metalloproteinase levels and polymorphonuclear cell infiltration after alkali injury
    • Sosne, G. et al 2005. Thymosin-beta4 modulates corneal matrix metalloproteinase levels and polymorphonuclear cell infiltration after alkali injury. Invest. Ophthalmol. Vis. Sci. 46: 2388-2395.
    • (2005) Invest. Ophthalmol. Vis. Sci. , vol.46 , pp. 2388-2395
    • Sosne, G.1
  • 49
    • 79955605472 scopus 로고    scopus 로고
    • Multiple facets of NF-kappaB in the heart: to be or not to NF-kappaB
    • Gordon, J.W., J.A. Shaw & L.A. Kirshenbaum 2011. Multiple facets of NF-kappaB in the heart: to be or not to NF-kappaB. Circ. Res. 108: 1122-1132.
    • (2011) Circ. Res. , vol.108 , pp. 1122-1132
    • Gordon, J.W.1    Shaw, J.A.2    Kirshenbaum, L.A.3
  • 50
    • 33947200192 scopus 로고    scopus 로고
    • Thymosin beta 4 suppression of corneal NFkappaB: a potential anti-inflammatory pathway
    • Sosne, G. et al 2007. Thymosin beta 4 suppression of corneal NFkappaB: a potential anti-inflammatory pathway. Exp. Eye Res. 84: 663-669.
    • (2007) Exp. Eye Res. , vol.84 , pp. 663-669
    • Sosne, G.1
  • 51
    • 79957922304 scopus 로고    scopus 로고
    • Thymosin beta4 inhibits TNF-alpha-induced NF-kappaB activation, IL-8 expression, and the sensitizing effects by its partners PINCH-1 and ILK
    • Qiu, P. et al 2011. Thymosin beta4 inhibits TNF-alpha-induced NF-kappaB activation, IL-8 expression, and the sensitizing effects by its partners PINCH-1 and ILK. Faseb J. 25: 1815-1826.
    • (2011) Faseb J. , vol.25 , pp. 1815-1826
    • Qiu, P.1
  • 52
    • 78751507979 scopus 로고    scopus 로고
    • Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart
    • Creemers, E.E. & Y.M. Pinto 2011. Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart. Cardiovasc. Res. 89: 265-272.
    • (2011) Cardiovasc. Res. , vol.89 , pp. 265-272
    • Creemers, E.E.1    Pinto, Y.M.2
  • 53
    • 77957729712 scopus 로고    scopus 로고
    • The origin of fibroblasts and mechanism of cardiac fibrosis
    • Krenning, G., E.M. Zeisberg & R. Kalluri 2010. The origin of fibroblasts and mechanism of cardiac fibrosis. J. Cell. Physiol. 225: 631-637.
    • (2010) J. Cell. Physiol. , vol.225 , pp. 631-637
    • Krenning, G.1    Zeisberg, E.M.2    Kalluri, R.3
  • 54
    • 76549099669 scopus 로고    scopus 로고
    • Emerging concepts in cardiac matrix biology
    • Espira, L. & M.P. Czubryt 2009. Emerging concepts in cardiac matrix biology. Can. J. Physiol. Pharmacol. 87: 996-1008.
    • (2009) Can. J. Physiol. Pharmacol. , vol.87 , pp. 996-1008
    • Espira, L.1    Czubryt, M.P.2
  • 55
    • 0842267835 scopus 로고    scopus 로고
    • Ac-SDKP reverses inflammation and fibrosis in rats with heart failure after myocardial infarction
    • Yang, F. et al 2004. Ac-SDKP reverses inflammation and fibrosis in rats with heart failure after myocardial infarction. Hypertension 43: 229-236.
    • (2004) Hypertension , vol.43 , pp. 229-236
    • Yang, F.1
  • 56
    • 34250803343 scopus 로고    scopus 로고
    • Decreased endogenous levels of Ac-SDKP promote organ fibrosis
    • Cavasin, M.A. et al 2007. Decreased endogenous levels of Ac-SDKP promote organ fibrosis. Hypertension 50: 130-136.
    • (2007) Hypertension , vol.50 , pp. 130-136
    • Cavasin, M.A.1
  • 58
    • 81555220895 scopus 로고    scopus 로고
    • ROS and RNS signaling in heart disorders: could antioxidant treatment be successful
    • Afanas'ev, I. 2011. ROS and RNS signaling in heart disorders: could antioxidant treatment be successful Oxid. Med. Cell. Longev. 2011: 293769.
    • (2011) Oxid. Med. Cell. Longev. , vol.2011 , pp. 293769
    • Afanas'ev, I.1
  • 59
    • 14644442283 scopus 로고    scopus 로고
    • Oxygen, oxidative stress, hypoxia, and heart failure
    • Giordano, F.J. 2005. Oxygen, oxidative stress, hypoxia, and heart failure. J. Clin. Invest. 115: 500-508.
    • (2005) J. Clin. Invest. , vol.115 , pp. 500-508
    • Giordano, F.J.1
  • 60
    • 0033588198 scopus 로고    scopus 로고
    • Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium
    • Ide, T. et al 1999. Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium. Circ. Res. 85: 357-363.
    • (1999) Circ. Res. , vol.85 , pp. 357-363
    • Ide, T.1
  • 61
    • 58249093939 scopus 로고    scopus 로고
    • How mitochondria produce reactive oxygen species
    • Murphy, M.P. 2009. How mitochondria produce reactive oxygen species. Biochem. J. 417: 1-13.
    • (2009) Biochem. J. , vol.417 , pp. 1-13
    • Murphy, M.P.1
  • 62
    • 47049124833 scopus 로고    scopus 로고
    • Thymosin beta-4 upregulates anti-oxidative enzymes and protects human cornea epithelial cells against oxidative damage
    • Ho, J.H. et al 2008. Thymosin beta-4 upregulates anti-oxidative enzymes and protects human cornea epithelial cells against oxidative damage. Br. J. Ophthalmol. 92: 992-997.
    • (2008) Br. J. Ophthalmol. , vol.92 , pp. 992-997
    • Ho, J.H.1
  • 63
    • 80055028395 scopus 로고    scopus 로고
    • Thymosin beta 4 prevents oxidative stress by targeting antioxidant and anti-apoptotic genes in cardiac fibroblasts
    • Kumar, S. & S. Gupta 2011. Thymosin beta 4 prevents oxidative stress by targeting antioxidant and anti-apoptotic genes in cardiac fibroblasts. PLoS One 6: e26912.
    • (2011) PLoS One , vol.6
    • Kumar, S.1    Gupta, S.2
  • 64
    • 0042859821 scopus 로고    scopus 로고
    • Role of the mitochondrial permeability transition in myocardial disease
    • Weiss, J.N. et al 2003. Role of the mitochondrial permeability transition in myocardial disease. Circ. Res. 93: 292-301.
    • (2003) Circ. Res. , vol.93 , pp. 292-301
    • Weiss, J.N.1
  • 65
    • 84555188518 scopus 로고    scopus 로고
    • Mitochondrial proteome remodelling in pressure overload-induced heart failure: the role of mitochondrial oxidative stress
    • Dai, D.F. et al 2012. Mitochondrial proteome remodelling in pressure overload-induced heart failure: the role of mitochondrial oxidative stress. Cardiovasc. Res. 93: 79-88.
    • (2012) Cardiovasc. Res. , vol.93 , pp. 79-88
    • Dai, D.F.1
  • 66
    • 9444269830 scopus 로고    scopus 로고
    • Nuclear localisation of the G-actin sequestering peptide thymosin beta4
    • Huff, T. et al 2004. Nuclear localisation of the G-actin sequestering peptide thymosin beta4. J. Cell Sci. 117: 5333-5341.
    • (2004) J. Cell Sci. , vol.117 , pp. 5333-5341
    • Huff, T.1
  • 67
    • 59449092492 scopus 로고    scopus 로고
    • Oxidative stress and left ventricular remodelling after myocardial infarction
    • Hori, M. & K. Nishida 2009. Oxidative stress and left ventricular remodelling after myocardial infarction. Cardiovasc. Res. 81: 457-464.
    • (2009) Cardiovasc. Res. , vol.81 , pp. 457-464
    • Hori, M.1    Nishida, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.