-
1
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi, D.R., M. Andjelkovic, B. Caudwell, P. Cron, N. Morrice, P. Cohen, and B.A. Hemmings. 1996. Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 15:6541-6551.
-
(1996)
EMBO J.
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
-
2
-
-
15644381754
-
Role of translocation in the activation and function of protein kinase B
-
Andjelkovic, M., D.R. Alessi, R. Meier, A. Fernandez, N.J. Lamb, M. Frech, P. Cron, P. Cohen, J.M. Lucocq, and B.A. Hemmings. 1997. Role of translocation in the activation and function of protein kinase B. J. Biol. Chem. 272:31515-31524.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 31515-31524
-
-
Andjelkovic, M.1
Alessi, D.R.2
Meier, R.3
Fernandez, A.4
Lamb, N.J.5
Frech, M.6
Cron, P.7
Cohen, P.8
Lucocq, J.M.9
Hemmings, B.A.10
-
3
-
-
0035499454
-
Ten years of protein kinase B signalling: A hard Akt to follow
-
Brazil, D.P., and B.A. Hemmings. 2001. Ten years of protein kinase B signalling: a hard Akt to follow. Trends Biochem. Sci. 26:657-664.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 657-664
-
-
Brazil, D.P.1
Hemmings, B.A.2
-
4
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley, L.C. 2002. The phosphoinositide 3-kinase pathway. Science. 296:1655-1657.
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
5
-
-
0032530482
-
Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase
-
Delcommenne, M., C. Tan, V. Gray, L. Rue, J. Woodgett, and S. Dedhar. 1998. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase. Proc. Natl. Acad. Sci. USA. 95:11211-11216.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 11211-11216
-
-
Delcommenne, M.1
Tan, C.2
Gray, V.3
Rue, L.4
Woodgett, J.5
Dedhar, S.6
-
6
-
-
0032053709
-
Mechanisms and consequences of activation of protein kinase B/Akt
-
Downward, J. 1998. Mechanisms and consequences of activation of protein kinase B/Akt. Curr. Opin. Cell Biol. 10:262-267.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 262-267
-
-
Downward, J.1
-
7
-
-
0036351317
-
Analysis of gene function in somatic mammalian cells using small interfering RNAs
-
Elbashir, S.M., J. Harborth, K. Weber, and T. Tuschl. 2002. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods. 26:199-213.
-
(2002)
Methods
, vol.26
, pp. 199-213
-
-
Elbashir, S.M.1
Harborth, J.2
Weber, K.3
Tuschl, T.4
-
9
-
-
0037205502
-
Laminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathways
-
Gu, J., A. Fujibayashi, K.M. Yamada, and K. Sekiguchi. 2002. Laminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathways. J. Biol. Chem. 277:19922-19928.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 19922-19928
-
-
Gu, J.1
Fujibayashi, A.2
Yamada, K.M.3
Sekiguchi, K.4
-
10
-
-
0037162291
-
Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1
-
Hill, M.M., J. Feng, and B.A. Hemmings. 2002. Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1. Curr. Biol. 12:1251-1255.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1251-1255
-
-
Hill, M.M.1
Feng, J.2
Hemmings, B.A.3
-
11
-
-
0030913673
-
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
-
Khwaja, A., P. Rodriguez-Viciana, S. Wennstrom, P.H. Warne, and J. Downward. 1997. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J. 16:2783-2793.
-
(1997)
EMBO J.
, vol.16
, pp. 2783-2793
-
-
Khwaja, A.1
Rodriguez-Viciana, P.2
Wennstrom, S.3
Warne, P.H.4
Downward, J.5
-
12
-
-
0030839766
-
Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation
-
King, W.G., M.D. Mattaliano, T.O. Chan, P.N. Tsichlis, and J.S. Brugge. 1997. Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation. Mol. Cell. Biol. 17:4406-4418.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 4406-4418
-
-
King, W.G.1
Mattaliano, M.D.2
Chan, T.O.3
Tsichlis, P.N.4
Brugge, J.S.5
-
13
-
-
0034845958
-
PKB/Akt: A key mediator of cell proliferation, survival and insulin responses?
-
Lawlor, M.A., and D.R. Alessi. 2001. PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J. Cell Sci. 114:2903-2910.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2903-2910
-
-
Lawlor, M.A.1
Alessi, D.R.2
-
14
-
-
0037196566
-
The alpha5beca1 integrin selectively enhances epidermal growth factor signaling to the phosphatidylinositol-3-kinase/Akt pathway in intestinal epithelial cells
-
Lee, J.W., and R.L. Juliano. 2002. The alpha5beca1 integrin selectively enhances epidermal growth factor signaling to the phosphatidylinositol-3-kinase/Akt pathway in intestinal epithelial cells. Biochim. Biophys. Acta. 1542:23-31.
-
(2002)
Biochim. Biophys. Acta
, vol.1542
, pp. 23-31
-
-
Lee, J.W.1
Juliano, R.L.2
-
15
-
-
0033378656
-
Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats
-
Li, F., Y. Zhang, and C. Wu. 1999. Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats. J. Cell Sci. 112:4589-4599.
-
(1999)
J. Cell Sci.
, vol.112
, pp. 4589-4599
-
-
Li, F.1
Zhang, Y.2
Wu, C.3
-
16
-
-
0033599029
-
Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism
-
Lynch, D.K., C.A. Ellis, P.A. Edwards, and I. Hiles. 1999. Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism. Oncogene. 18:8024-8032.
-
(1999)
Oncogene
, vol.18
, pp. 8024-8032
-
-
Lynch, D.K.1
Ellis, C.A.2
Edwards, P.A.3
Hiles, I.4
-
18
-
-
0036222549
-
Sensing the environment: A historical perspective on integrin signal transduction
-
Miranti, C.K., and J.S. Brugge. 2002. Sensing the environment: a historical perspective on integrin signal transduction. Nat. Cell Biol. 4:E83-E90.
-
(2002)
Nat. Cell Biol.
, vol.4
-
-
Miranti, C.K.1
Brugge, J.S.2
-
19
-
-
0034739856
-
Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion
-
Nikolopoulos, S.N., and C.E. Turner. 2000. Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion. J. Cell Biol 151:1435-1448.
-
(2000)
J. Cell Biol.
, vol.151
, pp. 1435-1448
-
-
Nikolopoulos, S.N.1
Turner, C.E.2
-
20
-
-
0037059789
-
Molecular dissection of actopaxin-integrin-linked kinase-paxillin interactions and their role in subcellular localization
-
Nikolopoulos, S.N., and C.E. Turner. 2002. Molecular dissection of actopaxin-integrin-linked kinase-paxillin interactions and their role in subcellular localization. J. Biol. Chem. 277:1568-1575.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1568-1575
-
-
Nikolopoulos, S.N.1
Turner, C.E.2
-
21
-
-
0035126590
-
Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily
-
Olski, T.M., A.A. Noegel, and E. Korenbaum. 2001. Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily. J. Cell Sci. 114:525-538.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 525-538
-
-
Olski, T.M.1
Noegel, A.A.2
Korenbaum, E.3
-
22
-
-
0036333737
-
Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B
-
Scheid, M.P., P.A. Marignani, and J.R. Woodgett. 2002. Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B. Mol. Cell. Biol. 22:6247-6260.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 6247-6260
-
-
Scheid, M.P.1
Marignani, P.A.2
Woodgett, J.R.3
-
23
-
-
0035972170
-
A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading
-
Tu, Y., Y. Huang, Z. Zhang, Y. Hua, and C. Wu. 2001. A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading. J. Cell Biol. 153:585-598.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 585-598
-
-
Tu, Y.1
Huang, Y.2
Zhang, Z.3
Hua, Y.4
Wu, C.5
-
24
-
-
0033594403
-
Akt/PKB localisation and 3′ phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction
-
Watton, S.J., and J. Downward. 1999. Akt/PKB localisation and 3′ phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction. Curr. Biol. 9:433-436.
-
(1999)
Curr. Biol.
, vol.9
, pp. 433-436
-
-
Watton, S.J.1
Downward, J.2
-
25
-
-
0035969233
-
Integrin-linked kinase (ILK) and its interactors: A new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes
-
Wu, C., and S. Dedhar. 2001. Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes. J. Cell Biol. 155:505-510.
-
(2001)
J. Cell Biol.
, vol.155
, pp. 505-510
-
-
Wu, C.1
Dedhar, S.2
-
26
-
-
0035844879
-
A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction
-
Yamaji, S., A. Suzuki, Y. Sugiyama, Y. Koide, M. Yoshida, H. Kanamori, H. Mohri, S. Ohno, and Y. Ishigatsubo. 2001. A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction. J. Cell Biol. 153:1251-1264.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1251-1264
-
-
Yamaji, S.1
Suzuki, A.2
Sugiyama, Y.3
Koide, Y.4
Yoshida, M.5
Kanamori, H.6
Mohri, H.7
Ohno, S.8
Ishigatsubo, Y.9
-
27
-
-
0037115611
-
Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites
-
Zhang, Y., K. Chen, Y. Tu, A. Velyvis, Y. Yang, J. Qin, and C. Wu. 2002. Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites. J. Cell Sci. 115:4777-4786.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 4777-4786
-
-
Zhang, Y.1
Chen, K.2
Tu, Y.3
Velyvis, A.4
Yang, Y.5
Qin, J.6
Wu, C.7
|