Thymosin β4 stimulates directional migration of human umbilical vein endothelial cells

FASEB Journal

Volumn 11, Issue 6, 1997, Pages 474-481

  Malinda, Katherine M ^a   Goldstein, Allan L ^b   Kleinman, Hynda K ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Angiogenesis; Human umbilical vein endothelial cells; Migration; T 4

Indexed keywords

G ACTIN; MATRIX METALLOPROTEINASE; THYMOSIN BETA4;

ANGIOGENESIS; ARTICLE; BASEMENT MEMBRANE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; UMBILICAL VEIN;

EID: 0030926245     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.11.6.9194528     Document Type: Article

References (39)

1. Kubota, Y., Kleinman, H. K., Martin, G. R., and Lawley, T. J. (1988) Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures. J. Cell Biol. 107, 1589-1598
2. Grant, D. S., Kinsella, J. L., Fridman, R., Auerbach, R., Piasecki, B. A., Yamada, Y., Zain, M., and Kleinman, H. K. (1992) Interaction of endothelial cells with a laminin A chain peptide (SIKVAV) in vitro and induction of angiogenic behavior in vivo. J. Cell. Physiol. 153, 614-625
3. 4 gene in differentiating endothelial cells. J. Cell Sci. 108, 3685-3694
4. 4 Cell 175, 1007-1014
5. Oates, K. K., and Goldstein, A. L. (1995) Thymosin. In Biologic Therapy of Cancer (DeVita, V. T., Hellman, S., and Rosenberg, S. A., eds) pp. 841-852, J. B. Lippincott, Philadelphia
6. Mihelic, M., and Voelter, W. (1994) Distribution and biological activity of β-thymosins. Amino Acids 6, 1-13
7. 4 sequesters the majority of G-actin in resting human polymorphonuclear leukocytes. J. Cell. Biol. 119, 1261-1270
8. 4 (Fx peptide) is a potent regulator of actin polymerization in living cells. Proc. Natl. Acad. Sci. USA 89, 4678-4682
9. Yu, F.-X., Lin, S.-C., Morrison-Bogorad, M., Atkinson, M. A., and Yin, H. L. (1993) Thymosin beta 10 and thymosin beta 4 are both actin monomer sequestering proteins. J. Biol. Chem. 268, 502-509
10. 10 on actin structures in living cells. Cell Motil. Cytoskel. 27, 13-25
11. Safer, D., and Nachmias, V. T. (1994) Beta thymosins as actin binding proteins. BioEssays 16, 473-479
12. 4 in PtK2 cells: effects on stress fibers, cytokinesis, and cell spreading. Cell Motil. Cytoskeleton 31, 307-322
13. Hu, S.-K., Low, T. L. K., and Goldstein, A. L. (1981) Modulation of terminal deoxynudeotidyl transferase activity by thymosin. Mol. Cell. Biochem. 41, 49-58
14. 4. J Cell. Biol. 257, 1000-1006
15. Low, T. L. K., Hu, S.-K., and Goldstein, A.L. (1981) Complete amino acid sequence of bovine thymosin: a thymic hormone that induces terminal deoxynucleotidyl transferase activity in thymocyte populations. Proc. Natl. Acad. Sci. USA 78, 1162-1166
16. 10 in rat brain and other tissues. J. Mol. Neurosci. 2, 35-44
17. Codon, M. R., and Hall, A. K. (1992) Expression of thymosin beta-4 and related genes in the developing brain. J. Mol. Neurosci. 3, 165-170
18. 4 gene is strongly activated in neural tissues during early postimplantation mouse development. Neuroscience Letters 184, 63-66
19. 4 gene during Xenopus laevis embryogenesis. Biochem. Biophys. Res. Commun. 184, 93-99
20. 4 gene in lymphocytes, macrophages, and granulocytes. J. Immunol. 139, 3840-3848
21. Hall, A. R. (1991) Differential expression of thymosin genes in human tumors and in the developing kidney. Int. J. Cancer 48, 672-677
22. 4 gene: preliminary characterization and expression in tissues, thymic cells, and lymphocytes. J. Immunol. 143, 2740-2744
23. 4 in serum: comparison of normal, cord, homosexual and AIDS serum. Int. J. Immunopharmacol. 8, 667-676
24. 4 in vitro and in vivo. AIDS Res. Human Retroviruses 10, 1525-1529
25. 4 expression is correlated with metastatic capacity of colorectal carcinomas. Biochem. Biophys. Res. Commun. 193, 706-710
26. Cockerill, G. W., Gamble, J. R., and Vadas, M. A. (1995) Angiogenesis: models and modulators. Int. Rev. Cytol. 159, 113-160
27. Hu, G.-F, Strydom, D. J., Fett, J. W., Riordan, J. F., and Vallee, B. L. (1993) Actin is a binding protein for angiogenin. Proc. Natl. Acad. Sci. USA 90, 1217-1221
28. Jaffe, E. A., Nachman, R. L., Becker, C. G., and Minick, C. R. (1973) Culture of endothelial cells derived from umbilical veins. Identification by morphological and immunological criteria. J Clin Invest. 52, 2745
29. Kibbey, M. C., Corcoran, M. L., Wahl, L. M., and Kleinman, H. K. (1994) Laminin SIKVAV peptide-induced angiogenesis in vivo is potentiated by neutrophils. J. Cell Phys. 160, 185-193
30. Kleinman, H. K., McGarvy, M. L., Liotta, L. A., Gehron-Robbey, P., Tryggvasson, K., and Martin, G. R. (1982) Isolation and characterization of type IV procollagen, laminin, and heparin sulfate proteoglycan from the EHS sarcoma. Biochemistry 24, 6188-6193
31. Lafrenie, R. M., Wahl, L. M., Epstein, J. S., Hewlett, I. K., Yamada, K. M., and Dhawan, S. (1996) HIV-1 tat protein promotes chemotaxis and invasive behavior by monocytes. J. Immunol. 157, 974-977
32. Kleiner, D. E., and Stetler-Stevenson, W. G. (1994) Quantitative zymography: detection of picogram quantities of gelatinases. Anal. Biochem. 218, 325-329
33. 4. Immunopharmacology 7, 9-16
34. 4 in human serum. J. Biol. Response Mod. 7, 91-96
35. Thurman, G. B., Low, T. L. K., Rossio, J. L., and Goldstein, A. L. (1981) Specific and nonspecific macrophage migration inhibition. In Lymphokines and Thymic Hormones: Their Potential Utilization in Cancer Therapeutics (Goldstein, A. L., and Chirigos, M. A., eds) pp. 145-157, Raven, New York
36. Sun, H.-Q., Kwiatkowska, K., and Lin, H. L. (1996) β-Thymosins are not simple actin monomer buffering proteins. J. Biol. Chem. 271, 9223-9230
37. Schnaper, H. W., Grant, D. S., Stetler-Stevenson, W. G., Fridman, R., D'Orazi, G., Murphy, A. N., Bird, R. E., Hoythya, M., Fuerst, T. R., French, D. L., Quigley, J. P., and Kleinman, H. K. (1993) Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis. J. Cell. Phys. 156, 235-246
38. Passaniti, A., Taylor, R. M., Pili, R., Guo, Y. Long, P. V., Haney, J. A., Pauly, R. R., Grant, D. G., and Martin, G. R. (1992) A simple, quantitative method for assessing angiogenesis and antiangiogenic agents using reconstituted basement membrane, heparin, and fibroblast growth factor. Lab. Invest. 67, 519-528
39. Frohm, M., Gunne, H., Bergman, A.-C., Agerberth, B., Bergman, T., Boman, A., Liden, S., Jornvall, H., and Boman, H.G. (1996) Biochemical and antibacterial analysis of human wound and blister fluid. Eur. J. Biochem. 237, 86-92