Estrogen receptor potentiates mTORC2 signaling in breast cancer cells by upregulating superoxide anions

Free Radical Biology and Medicine

Volumn 53, Issue 10, 2012, Pages 1929-1941

  Kumari Kanchan, Ranjana ^a   Tripathi, Chakrapani ^a   Singh Baghel, Khemraj ^a   Kumar Dwivedi, Shailendra ^a   Kumar, Balawant ^a   Sanyal, Sabyasachi ^a   Sharma, Sharad ^a   Mitra, Kalyan ^a   Garg, Vivek ^b   Singh, Kavita ^a   Sultana, Sarwat ^c   Kamal Tripathi, Raj ^a   Kumar Rath, Srikanta ^a   Bhadauria, Smrati ^a  

^a Central Drug Research Institute CSIR   (India)

^b Lucknow Cancer Institute   (India)

^c HAMDARD UNIVERSITY   (India)

Author keywords

Estrogen receptor; Free radicals; mTORC2; Redox signaling; ROS; Superoxide anions

Indexed keywords

ACETYLCYSTEINE; ANION; ESTROGEN RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MANGANESE DERIVATIVE; MANGANESE TETRAKIS(4 BENZOIC ACID)PORPHYRIN; OXYGEN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; SUPEROXIDE; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CONFOCAL MICROSCOPY; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOCHONDRION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; UPREGULATION;

BREAST NEOPLASMS; CELL LINE, TUMOR; DISEASE PROGRESSION; ESTRADIOL; FEMALE; HUMANS; MCF-7 CELLS; MITOCHONDRIA; MULTIPROTEIN COMPLEXES; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; RECEPTORS, ESTROGEN; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; SUPEROXIDES; TOR SERINE-THREONINE KINASES; UP-REGULATION;

MAMMALIA;

EID: 84867358532     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.08.595     Document Type: Article

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