-
1
-
-
35648957666
-
Biochemistry of ghrelin precursor peptides
-
Pemberton C, Richards AM. Biochemistry of ghrelin precursor peptides. Vitam Horm 2008, 77:13-30.
-
(2008)
Vitam Horm
, vol.77
, pp. 13-30
-
-
Pemberton, C.1
Richards, A.M.2
-
2
-
-
58149492750
-
Obestatin, obesity and diabetes
-
10.1016/j.peptides.2008.10.002, 18992781
-
Ren AJ, Guo ZF, Wang YK, Lin L, Zheng X, Yuan WJ. Obestatin, obesity and diabetes. Peptides 2009, 30:439-444. 10.1016/j.peptides.2008.10.002, 18992781.
-
(2009)
Peptides
, vol.30
, pp. 439-444
-
-
Ren, A.J.1
Guo, Z.F.2
Wang, Y.K.3
Lin, L.4
Zheng, X.5
Yuan, W.J.6
-
3
-
-
40449096914
-
Obestatin: its physicochemical characteristics and physiological functions
-
10.1016/j.peptides.2008.01.012, 18325633
-
Tang SQ, Jiang QY, Zhang YL, Zhu XT, Shu G, Gao P, Feng DY, Wang XQ, Dong XY. Obestatin: its physicochemical characteristics and physiological functions. Peptides 2008, 29:639-645. 10.1016/j.peptides.2008.01.012, 18325633.
-
(2008)
Peptides
, vol.29
, pp. 639-645
-
-
Tang, S.Q.1
Jiang, Q.Y.2
Zhang, Y.L.3
Zhu, X.T.4
Shu, G.5
Gao, P.6
Feng, D.Y.7
Wang, X.Q.8
Dong, X.Y.9
-
4
-
-
27744600963
-
Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake
-
10.1126/science.1117255, 16284174
-
Zhang JV, Ren PG, Avsian-Kretchmer O, Luo CW, Rauch R, Klein C, Hsueh AJW. Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science 2005, 310:996-999. 10.1126/science.1117255, 16284174.
-
(2005)
Science
, vol.310
, pp. 996-999
-
-
Zhang, J.V.1
Ren, P.G.2
Avsian-Kretchmer, O.3
Luo, C.W.4
Rauch, R.5
Klein, C.6
Hsueh, A.J.W.7
-
5
-
-
33846935917
-
Obestatin - a ghrelin associated peptide that does not hold its promise to suppress food intake and motility
-
Gourcerol H, Tache Y. Obestatin - a ghrelin associated peptide that does not hold its promise to suppress food intake and motility. Neurogastrenterol Motil 2007, 19:161-165.
-
(2007)
Neurogastrenterol Motil
, vol.19
, pp. 161-165
-
-
Gourcerol, H.1
Tache, Y.2
-
6
-
-
51349166631
-
Characterization of obestatin in rat and human stomach and plasma and its lack of acute effect on feeding behaviour in rodents
-
10.1677/JOE-08-0082, 18480381
-
Mondal MS, Toshinai K, Ueno H, Koshinaka K, Nakazato M. Characterization of obestatin in rat and human stomach and plasma and its lack of acute effect on feeding behaviour in rodents. J Endocrinol 2008, 198:339-346. 10.1677/JOE-08-0082, 18480381.
-
(2008)
J Endocrinol
, vol.198
, pp. 339-346
-
-
Mondal, M.S.1
Toshinai, K.2
Ueno, H.3
Koshinaka, K.4
Nakazato, M.5
-
7
-
-
33751062773
-
Central obestatin administration does not modify either spontaneous or ghrelin-induced food intake in rats
-
Seoane LM, Al-Massadi O, Pazos Y, Pagotto U, Casanueva FF. Central obestatin administration does not modify either spontaneous or ghrelin-induced food intake in rats. J Endocrinol Invest 2006, 29:RC13-15.
-
(2006)
J Endocrinol Invest
, vol.29
-
-
Seoane, L.M.1
Al-Massadi, O.2
Pazos, Y.3
Pagotto, U.4
Casanueva, F.F.5
-
8
-
-
33845883349
-
GPR39 signaling is stimulated by zinc ions but not by obestatin
-
Holst B, Egerod KL, Schild E, Vickers SP, Cheetham S, Gerlach LO, Storjohann L, Stidsen CE, Jones R, Beck-Sickinger AG, Schwartz TW. GPR39 signaling is stimulated by zinc ions but not by obestatin. Endocrinology 2007, 148:13-20.
-
(2007)
Endocrinology
, vol.148
, pp. 13-20
-
-
Holst, B.1
Egerod, K.L.2
Schild, E.3
Vickers, S.P.4
Cheetham, S.5
Gerlach, L.O.6
Storjohann, L.7
Stidsen, C.E.8
Jones, R.9
Beck-Sickinger, A.G.10
Schwartz, T.W.11
-
9
-
-
33750980992
-
Obestatin does not activate orphan G protein-coupled receptor GPR39
-
10.1016/j.bbrc.2006.09.141, 17054911
-
Lauwers E, Landuyt B, Arckens L, Schoofs L, Luyten W. Obestatin does not activate orphan G protein-coupled receptor GPR39. Biochem Biophys Res Commun 2006, 351:21-25. 10.1016/j.bbrc.2006.09.141, 17054911.
-
(2006)
Biochem Biophys Res Commun
, vol.351
, pp. 21-25
-
-
Lauwers, E.1
Landuyt, B.2
Arckens, L.3
Schoofs, L.4
Luyten, W.5
-
10
-
-
42449124783
-
Obestatin promotes survival of pancreatic β-cells and human islets and induces expression of genes involved in the regulation of β-cell mass and function
-
10.2337/db07-1104, 18162507
-
Granata R, Settanni F, Gallo D, Trovato L, Biancone L, Cantaluppi V, Nano R, Annunziata M, Campiglia P, Arnoletti E, Ghè C, Volante M, Papotti M, Muccioli G, Ghigo E. Obestatin promotes survival of pancreatic β-cells and human islets and induces expression of genes involved in the regulation of β-cell mass and function. Diabetes 2008, 57:967-79. 10.2337/db07-1104, 18162507.
-
(2008)
Diabetes
, vol.57
, pp. 967-979
-
-
Granata, R.1
Settanni, F.2
Gallo, D.3
Trovato, L.4
Biancone, L.5
Cantaluppi, V.6
Nano, R.7
Annunziata, M.8
Campiglia, P.9
Arnoletti, E.10
Ghè, C.11
Volante, M.12
Papotti, M.13
Muccioli, G.14
Ghigo, E.15
-
11
-
-
77954749961
-
Unacylated ghrelin and obestatin increase islet cell mass and prevent diabetes in streptozotocin-treated newborn rats
-
10.1677/JME-09-0141, 20382773
-
Granata R, Volante M, Settanni F, Gauna C, Ghé C, Annunziata M, Deidda B, Gesmundo I, Abribat T, van der Lely AJ, Muccioli G, Ghigo E, Papotti M. Unacylated ghrelin and obestatin increase islet cell mass and prevent diabetes in streptozotocin-treated newborn rats. J Mol Endocrinol 2010, 45:9-17. 10.1677/JME-09-0141, 20382773.
-
(2010)
J Mol Endocrinol
, vol.45
, pp. 9-17
-
-
Granata, R.1
Volante, M.2
Settanni, F.3
Gauna, C.4
Ghé, C.5
Annunziata, M.6
Deidda, B.7
Gesmundo, I.8
Abribat, T.9
van der Lely, A.J.10
Muccioli, G.11
Ghigo, E.12
Papotti, M.13
-
12
-
-
84858731418
-
Des-Acyl Ghrelin Fragments and Analogues Promote Survival of Pancreatic β-Cells and Human Pancreatic Islets and Prevent Diabetes in Streptozotocin-Treated Rats
-
10.1021/jm201223m, 22352743
-
Granata R, Settanni F, Julien M, Nano R, Togliatto G, Trombetta A, Gallo D, Piemonti L, Brizzi MF, Abribat T, van Der Lely AJ, Ghigo E. Des-Acyl Ghrelin Fragments and Analogues Promote Survival of Pancreatic β-Cells and Human Pancreatic Islets and Prevent Diabetes in Streptozotocin-Treated Rats. J Med Chem 2012, 55:2585-96. 10.1021/jm201223m, 22352743.
-
(2012)
J Med Chem
, vol.55
, pp. 2585-2596
-
-
Granata, R.1
Settanni, F.2
Julien, M.3
Nano, R.4
Togliatto, G.5
Trombetta, A.6
Gallo, D.7
Piemonti, L.8
Brizzi, M.F.9
Abribat, T.10
van Der Lely, A.J.11
Ghigo, E.12
-
13
-
-
33646534187
-
Ghrelin prevents development of diabetes at adult age in streptozotocin-treated newborn rats
-
10.1007/s00125-006-0226-3, 16570155
-
Irako T, Akamizu T, Hosoda H, Iwakura H, Ariyasu H, Tojo K, Tajima N, Kangawa K. Ghrelin prevents development of diabetes at adult age in streptozotocin-treated newborn rats. Diabetologia 2006, 49(6):1264-73. 10.1007/s00125-006-0226-3, 16570155.
-
(2006)
Diabetologia
, vol.49
, Issue.6
, pp. 1264-1273
-
-
Irako, T.1
Akamizu, T.2
Hosoda, H.3
Iwakura, H.4
Ariyasu, H.5
Tojo, K.6
Tajima, N.7
Kangawa, K.8
-
14
-
-
39049173432
-
Obestatin is present in saliva: alterations in obestatin and ghrelin levels of saliva and serum in ischemic heart disease
-
10.5483/BMBRep.2008.41.1.055, 18304451
-
Ozbay Y, Aydin S, Dagli AF, Akbulut M, Dagli N, Kilic N, Rahman A, Sahin I, Polat V, Ozercan HI, Arslan N, Sensoy D. Obestatin is present in saliva: alterations in obestatin and ghrelin levels of saliva and serum in ischemic heart disease. BMB Rep 2008, 41:55-61. 10.5483/BMBRep.2008.41.1.055, 18304451.
-
(2008)
BMB Rep
, vol.41
, pp. 55-61
-
-
Ozbay, Y.1
Aydin, S.2
Dagli, A.F.3
Akbulut, M.4
Dagli, N.5
Kilic, N.6
Rahman, A.7
Sahin, I.8
Polat, V.9
Ozercan, H.I.10
Arslan, N.11
Sensoy, D.12
-
15
-
-
38149009484
-
Plasma obestatin levels are lower in obese and post-gastrectomy subjects, but do not change in response to a meal
-
Huda MS, Durham BH, Wong SP, Deepak D, Kerrigan D, McCulloch P, Ranganath L, Pinkney J, Wilding JP. Plasma obestatin levels are lower in obese and post-gastrectomy subjects, but do not change in response to a meal. Int J Obes (Lond) 2008, 32:129-135.
-
(2008)
Int J Obes (Lond)
, vol.32
, pp. 129-135
-
-
Huda, M.S.1
Durham, B.H.2
Wong, S.P.3
Deepak, D.4
Kerrigan, D.5
McCulloch, P.6
Ranganath, L.7
Pinkney, J.8
Wilding, J.P.9
-
16
-
-
70449659327
-
Disturbance of circulating ghrelin and obestatin in chronic heart failure patients especially in those with cachexia
-
10.1016/j.peptides.2009.07.026, 19666068
-
Xin X, Ren AJ, Zheng X, Qin YW, Zhao XX, Yuan WJ, Guo ZF. Disturbance of circulating ghrelin and obestatin in chronic heart failure patients especially in those with cachexia. Peptides 2009, 30:2281-2285. 10.1016/j.peptides.2009.07.026, 19666068.
-
(2009)
Peptides
, vol.30
, pp. 2281-2285
-
-
Xin, X.1
Ren, A.J.2
Zheng, X.3
Qin, Y.W.4
Zhao, X.X.5
Yuan, W.J.6
Guo, Z.F.7
-
17
-
-
73949139015
-
Plasma ghrelin and obestatin levels are increased in spontaneously hypertensive rats
-
10.1016/j.peptides.2009.11.018, 19944125
-
Li ZF, Guo ZF, Cao J, Hu JQ, Zhao XX, Xu RL, Huang XM, Qin YW, Zheng X. Plasma ghrelin and obestatin levels are increased in spontaneously hypertensive rats. Peptides 2010, 31:297-300. 10.1016/j.peptides.2009.11.018, 19944125.
-
(2010)
Peptides
, vol.31
, pp. 297-300
-
-
Li, Z.F.1
Guo, Z.F.2
Cao, J.3
Hu, J.Q.4
Zhao, X.X.5
Xu, R.L.6
Huang, X.M.7
Qin, Y.W.8
Zheng, X.9
-
18
-
-
77955455608
-
Obestatin affords cardioprotection to the ischemic-reperfused isolated rat heart and inhibits apoptosis in cultures of similarly stressed cardiomyocytes
-
10.1152/ajpheart.00800.2009, 20525876
-
Alloatti G, Arnoletti E, Bassino E, Penna C, Perrelli MG, Ghe C, Muccioli G. Obestatin affords cardioprotection to the ischemic-reperfused isolated rat heart and inhibits apoptosis in cultures of similarly stressed cardiomyocytes. Am J Physiol Heart Circ Physiol 2010, 299:H470-481. 10.1152/ajpheart.00800.2009, 20525876.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.299
-
-
Alloatti, G.1
Arnoletti, E.2
Bassino, E.3
Penna, C.4
Perrelli, M.G.5
Ghe, C.6
Muccioli, G.7
-
19
-
-
32644448320
-
The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy
-
10.1016/j.jacc.2005.09.050, 16487830
-
Asbun J, Villarreal FJ. The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy. J Am Coll Cardiol 2006, 47:693-700. 10.1016/j.jacc.2005.09.050, 16487830.
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 693-700
-
-
Asbun, J.1
Villarreal, F.J.2
-
20
-
-
39949085776
-
Oxidative stress and vascular disease in diabetes: is the dichotomization of insulin signaling still valid?
-
10.1016/j.freeradbiomed.2007.12.021, 18191647
-
Avogaro A, de Kreutzenberg SV, Fadini GP. Oxidative stress and vascular disease in diabetes: is the dichotomization of insulin signaling still valid?. Free Radic Biol Med 2008, 44:1209-1215. 10.1016/j.freeradbiomed.2007.12.021, 18191647.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 1209-1215
-
-
Avogaro, A.1
de Kreutzenberg, S.V.2
Fadini, G.P.3
-
21
-
-
0037164747
-
Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/Akt
-
10.1083/jcb.200207165, 2173981, 12486113
-
Baldanzi G, Filigheddu N, Cutrupi S, Catapano F, Bonissoni S, Fubini A, Malan D, Baj G, Granata R, Broglio F, Papotti M, Surico N, Bussolino F, Isgaard J, Deghenghi R, Sinigaglia F, Prat M, Muccioli G, Ghigo E, Graziani A. Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/Akt. J Cell Biol 2002, 159:1029-1037. 10.1083/jcb.200207165, 2173981, 12486113.
-
(2002)
J Cell Biol
, vol.159
, pp. 1029-1037
-
-
Baldanzi, G.1
Filigheddu, N.2
Cutrupi, S.3
Catapano, F.4
Bonissoni, S.5
Fubini, A.6
Malan, D.7
Baj, G.8
Granata, R.9
Broglio, F.10
Papotti, M.11
Surico, N.12
Bussolino, F.13
Isgaard, J.14
Deghenghi, R.15
Sinigaglia, F.16
Prat, M.17
Muccioli, G.18
Ghigo, E.19
Graziani, A.20
more..
-
22
-
-
33748365415
-
Diabetic cardiomyopathy
-
10.1016/j.ecl.2006.05.003, 16959587
-
Fonarow GC, Srikanthan P. Diabetic cardiomyopathy. Endocrinol Metab Clin North Am 2006, 35:575-599. 10.1016/j.ecl.2006.05.003, 16959587.
-
(2006)
Endocrinol Metab Clin North Am
, vol.35
, pp. 575-599
-
-
Fonarow, G.C.1
Srikanthan, P.2
-
23
-
-
34547444891
-
Mechanistic insights into diabetes mellitus and oxidative stress
-
10.2174/092986707781058968, 2447161, 17627510
-
Maiese K, Chong ZZ, Shang YC. Mechanistic insights into diabetes mellitus and oxidative stress. Curr Med Chem 2007, 14:1729-1738. 10.2174/092986707781058968, 2447161, 17627510.
-
(2007)
Curr Med Chem
, vol.14
, pp. 1729-1738
-
-
Maiese, K.1
Chong, Z.Z.2
Shang, Y.C.3
-
24
-
-
6344292389
-
Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species
-
10.1074/jbc.M404421200, 15265871
-
Zou MH, Kirkpatrick SS, Davis BJ, Nelson JS, Wiles WG, Schlattner U, Neumann D, Brownlee M, Freeman MB, Goldman MH. Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species. J Biol Chem 2004, 279(42):43940-51. 10.1074/jbc.M404421200, 15265871.
-
(2004)
J Biol Chem
, vol.279
, Issue.42
, pp. 43940-43951
-
-
Zou, M.H.1
Kirkpatrick, S.S.2
Davis, B.J.3
Nelson, J.S.4
Wiles, W.G.5
Schlattner, U.6
Neumann, D.7
Brownlee, M.8
Freeman, M.B.9
Goldman, M.H.10
-
25
-
-
21644453934
-
Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase
-
10.1074/jbc.C500175200, 15899896
-
Kola B, Hubina E, Tucci SA, Kirkham TC, Garcia EA, Mitchell SE, Williams LM, Hawley SA, Hardie DG, Grossman AB, Korbonits M. Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase. J Biol Chem 2005, 280:25196-25201. 10.1074/jbc.C500175200, 15899896.
-
(2005)
J Biol Chem
, vol.280
, pp. 25196-25201
-
-
Kola, B.1
Hubina, E.2
Tucci, S.A.3
Kirkham, T.C.4
Garcia, E.A.5
Mitchell, S.E.6
Williams, L.M.7
Hawley, S.A.8
Hardie, D.G.9
Grossman, A.B.10
Korbonits, M.11
-
27
-
-
78651196288
-
A colorimetric micro-method for the determination of glutathione
-
1206606, 14340062
-
Owens CWI, Belcher RV. A colorimetric micro-method for the determination of glutathione. Biochem J 1965, 94:705-711. 1206606, 14340062.
-
(1965)
Biochem J
, vol.94
, pp. 705-711
-
-
Owens, C.W.I.1
Belcher, R.V.2
-
28
-
-
35948975083
-
Heterogeneity of ghrelin/growth hormone secretagogue receptors. Toward the understanding of the molecular identity of novel ghrelin/GHS receptors
-
10.1159/000105141, 17622734
-
Muccioli G, Baragli A, Granata R, Papotti M, Ghigo E. Heterogeneity of ghrelin/growth hormone secretagogue receptors. Toward the understanding of the molecular identity of novel ghrelin/GHS receptors. Neuroendocrinology 2007, 86:147-164. 10.1159/000105141, 17622734.
-
(2007)
Neuroendocrinology
, vol.86
, pp. 147-164
-
-
Muccioli, G.1
Baragli, A.2
Granata, R.3
Papotti, M.4
Ghigo, E.5
-
29
-
-
37549058838
-
Oxidative stress triggers cardiac fibrosis in the heart of diabetic rats
-
Aragno M, Mastrocola R, Alloatti G, Vercellinatto I, Bardini P, Geuna S, Catalano MG, Danni O, Boccuzzi G. Oxidative stress triggers cardiac fibrosis in the heart of diabetic rats. Endocrinology 2008, 149:380-388.
-
(2008)
Endocrinology
, vol.149
, pp. 380-388
-
-
Aragno, M.1
Mastrocola, R.2
Alloatti, G.3
Vercellinatto, I.4
Bardini, P.5
Geuna, S.6
Catalano, M.G.7
Danni, O.8
Boccuzzi, G.9
-
30
-
-
0030770245
-
Impaired contractile response to β adrenoceptor stimulation in diabetic rat hearts: alterations in β adrenoceptors-G protein-adenylate cyclase system and phospholamban phosphorylation
-
Gando S, Hattori Y, Akaishi Y, Nishihira J, Kanno M. Impaired contractile response to β adrenoceptor stimulation in diabetic rat hearts: alterations in β adrenoceptors-G protein-adenylate cyclase system and phospholamban phosphorylation. J Pharmacol Exp Ther 1997, 282:475-84.
-
(1997)
J Pharmacol Exp Ther
, vol.282
, pp. 475-484
-
-
Gando, S.1
Hattori, Y.2
Akaishi, Y.3
Nishihira, J.4
Kanno, M.5
-
31
-
-
67650914230
-
AMPK in Health and Disease
-
10.1152/physrev.00011.2008, 19584320
-
Steinberg GR, Kemp BE. AMPK in Health and Disease. Physiol Rev 2009, 89:1025-1078. 10.1152/physrev.00011.2008, 19584320.
-
(2009)
Physiol Rev
, vol.89
, pp. 1025-1078
-
-
Steinberg, G.R.1
Kemp, B.E.2
-
32
-
-
44649098808
-
Ghrelin, des-acyl ghrelin and obestatin: Three pieces of the same puzzle
-
10.1016/j.peptides.2008.02.018, 18396350
-
Soares JB, Leite-Moreira AF. Ghrelin, des-acyl ghrelin and obestatin: Three pieces of the same puzzle. Peptides 2008, 29:1255-1270. 10.1016/j.peptides.2008.02.018, 18396350.
-
(2008)
Peptides
, vol.29
, pp. 1255-1270
-
-
Soares, J.B.1
Leite-Moreira, A.F.2
-
33
-
-
79958788035
-
Cardiovascular actions of ghrelin and growth hormone-releasing hormone
-
Granata R, Isgaard J, Alloatti G, Ghigo E. Cardiovascular actions of ghrelin and growth hormone-releasing hormone. Exp Biol Med 2011, 236:505-514.
-
(2011)
Exp Biol Med
, vol.236
, pp. 505-514
-
-
Granata, R.1
Isgaard, J.2
Alloatti, G.3
Ghigo, E.4
-
34
-
-
34948870833
-
In vivo and in vitro antioxidant activity of ghrelin: attenuation of gastric ischemic injury in the rat
-
10.1111/j.1440-1746.2006.04696.x, 17914952
-
El Eter E, Al Tuwaijiri A, Hagar H, Arafa M. In vivo and in vitro antioxidant activity of ghrelin: attenuation of gastric ischemic injury in the rat. J Gastroenterol Hepatol 2007, 22:1791-1799. 10.1111/j.1440-1746.2006.04696.x, 17914952.
-
(2007)
J Gastroenterol Hepatol
, vol.22
, pp. 1791-1799
-
-
El Eter, E.1
Al Tuwaijiri, A.2
Hagar, H.3
Arafa, M.4
-
35
-
-
34548427342
-
Effect of ghrelin on human endothelial cells apoptosis induced by high glucose
-
10.1016/j.bbrc.2007.08.021, 17719561
-
Zhao H, Liu G, Wang Q, Ding L, Cai H, Jiang H, Xin Z. Effect of ghrelin on human endothelial cells apoptosis induced by high glucose. Biochem Biophys Res Commun 2007, 362:677-681. 10.1016/j.bbrc.2007.08.021, 17719561.
-
(2007)
Biochem Biophys Res Commun
, vol.362
, pp. 677-681
-
-
Zhao, H.1
Liu, G.2
Wang, Q.3
Ding, L.4
Cai, H.5
Jiang, H.6
Xin, Z.7
-
36
-
-
41149150716
-
NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities
-
10.2337/dc08-s247, 18227481
-
Paravicini TM, Touyz RM. NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities. Diabetes Care 2008, 31(2):S170-180. 10.2337/dc08-s247, 18227481.
-
(2008)
Diabetes Care
, vol.31
, Issue.2
-
-
Paravicini, T.M.1
Touyz, R.M.2
-
37
-
-
80455143341
-
Pathophysiology of myocardial reperfusion injury: preconditioning, postconditioning, and translational aspects of protective measures
-
10.1152/ajpheart.00553.2011, 21856909
-
Sanada S, Komuro I, Kitakaze M. Pathophysiology of myocardial reperfusion injury: preconditioning, postconditioning, and translational aspects of protective measures. Am J Physiol Heart Circ Physiol 2011, 301:H1723-41. 10.1152/ajpheart.00553.2011, 21856909.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
-
-
Sanada, S.1
Komuro, I.2
Kitakaze, M.3
-
38
-
-
70449727681
-
Ghrelin reverses experimental diabetic neuropathy in mice
-
10.1016/j.bbrc.2009.08.171, 19733151
-
Kyoraku I, Shiomi K, Kangawa K, Nakazato M. Ghrelin reverses experimental diabetic neuropathy in mice. Biochem Biophys Res Commun 2009, 389:405-408. 10.1016/j.bbrc.2009.08.171, 19733151.
-
(2009)
Biochem Biophys Res Commun
, vol.389
, pp. 405-408
-
-
Kyoraku, I.1
Shiomi, K.2
Kangawa, K.3
Nakazato, M.4
-
39
-
-
84855588454
-
Myocardial and metabolic dysfunction in type 2 diabetic rats: impact of ghrelin
-
10.1139/y11-103, 22188509
-
Hussein AA, Abdel-Aziz A, Gabr M, Hemmaid KZ. Myocardial and metabolic dysfunction in type 2 diabetic rats: impact of ghrelin. Can J Physiol Pharmacol 2012, 90:99-111. 10.1139/y11-103, 22188509.
-
(2012)
Can J Physiol Pharmacol
, vol.90
, pp. 99-111
-
-
Hussein, A.A.1
Abdel-Aziz, A.2
Gabr, M.3
Hemmaid, K.Z.4
-
40
-
-
79953045959
-
Inhibition of NADPH oxidase alleviates experimental diabetes-induced myocardial contractile dysfunction
-
10.1111/j.1463-1326.2011.01369.x, 21272185
-
Roe ND, Thomas DP, Ren J. Inhibition of NADPH oxidase alleviates experimental diabetes-induced myocardial contractile dysfunction. Diabetes Obes Metab 2011, 13:465-73. 10.1111/j.1463-1326.2011.01369.x, 21272185.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 465-473
-
-
Roe, N.D.1
Thomas, D.P.2
Ren, J.3
-
41
-
-
77951297902
-
Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction
-
10.1007/s10557-010-6222-3, 2874156, 20229055
-
Paiva MA, Gonçalves LM, Providência LA, Davidson SM, Yellon DM, Mocanu MM. Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction. Cardiovasc Drugs Ther 2010, 24:25-32. 10.1007/s10557-010-6222-3, 2874156, 20229055.
-
(2010)
Cardiovasc Drugs Ther
, vol.24
, pp. 25-32
-
-
Paiva, M.A.1
Gonçalves, L.M.2
Providência, L.A.3
Davidson, S.M.4
Yellon, D.M.5
Mocanu, M.M.6
-
42
-
-
39549092137
-
AMP-activated protein kinase conducts the ischemic stress response orchestra
-
10.1161/CIRCULATIONAHA.107.713115, 18268160
-
Young LH. AMP-activated protein kinase conducts the ischemic stress response orchestra. Circulation 2008, 117:832-840. 10.1161/CIRCULATIONAHA.107.713115, 18268160.
-
(2008)
Circulation
, vol.117
, pp. 832-840
-
-
Young, L.H.1
-
43
-
-
0027469730
-
Glycolysis is necessary to preserve myocardial Ca2+ homeostasis during beta-adrenergic stimulation
-
Nakamura K, Kusuoka H, Ambrosio G, Becker LC. Glycolysis is necessary to preserve myocardial Ca2+ homeostasis during beta-adrenergic stimulation. Am J Physiol 1993, 264:H670-H678.
-
(1993)
Am J Physiol
, vol.264
-
-
Nakamura, K.1
Kusuoka, H.2
Ambrosio, G.3
Becker, L.C.4
-
44
-
-
0027189905
-
The functional recovery of post-ischemic myocardium requires glycolysis during early reperfusion
-
10.1006/jmcc.1993.1033, 8510169
-
Jeremy RW, Ambrosio G, Pike MM, Jacobus WE, Becker LC. The functional recovery of post-ischemic myocardium requires glycolysis during early reperfusion. J Mol Cell Cardiol 1993, 25(3):261-76. 10.1006/jmcc.1993.1033, 8510169.
-
(1993)
J Mol Cell Cardiol
, vol.25
, Issue.3
, pp. 261-276
-
-
Jeremy, R.W.1
Ambrosio, G.2
Pike, M.M.3
Jacobus, W.E.4
Becker, L.C.5
-
45
-
-
14344257169
-
AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells
-
10.1016/j.bbrc.2004.09.177, 15504342
-
Cacicedo JM, Yagihashi N, Keaney JF, Ruderman NB, Ido Y. AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells. Biochem Biophys Res Commun 2004, 324:1204-1209. 10.1016/j.bbrc.2004.09.177, 15504342.
-
(2004)
Biochem Biophys Res Commun
, vol.324
, pp. 1204-1209
-
-
Cacicedo, J.M.1
Yagihashi, N.2
Keaney, J.F.3
Ruderman, N.B.4
Ido, Y.5
-
46
-
-
59649091027
-
An ezrin/calpain/PI3K/AMPK/eNOSs1179 signaling cascade mediating VEGF-dependent endothelial nitric oxide production
-
2720268, 19038867
-
Youn JY, Wang T, Cai H. An ezrin/calpain/PI3K/AMPK/eNOSs1179 signaling cascade mediating VEGF-dependent endothelial nitric oxide production. Circ Res 2009, 104:50-59. 2720268, 19038867.
-
(2009)
Circ Res
, vol.104
, pp. 50-59
-
-
Youn, J.Y.1
Wang, T.2
Cai, H.3
-
47
-
-
78651589386
-
Glucagon-like peptide-1 enhances cardiac L-type Ca2+ currents via activation of the cAMP-dependent protein kinase A pathway
-
10.1186/1475-2840-10-6, 3037307, 21251280
-
Xiao XF, Nikolskaya A, Jaye DA, Sigg DC. Glucagon-like peptide-1 enhances cardiac L-type Ca2+ currents via activation of the cAMP-dependent protein kinase A pathway. Cardiovasc Diabetol 2011, 10:6. 10.1186/1475-2840-10-6, 3037307, 21251280.
-
(2011)
Cardiovasc Diabetol
, vol.10
, pp. 6
-
-
Xiao, X.F.1
Nikolskaya, A.2
Jaye, D.A.3
Sigg, D.C.4
-
48
-
-
45549105772
-
Dual roles of the MAPK/ERK1/2 cell signaling pathway after stroke
-
10.1002/jnr.21604, 18189318
-
Sawe N, Steinberg G, Zhao H. Dual roles of the MAPK/ERK1/2 cell signaling pathway after stroke. J Neurosci Res 2008, 86:1659-69. 10.1002/jnr.21604, 18189318.
-
(2008)
J Neurosci Res
, vol.86
, pp. 1659-1669
-
-
Sawe, N.1
Steinberg, G.2
Zhao, H.3
-
49
-
-
79551679143
-
Reperfusion injury salvage kinase and survivor activating factor enhancement pro-survival signaling pathways in ischemic postconditioning: two sides of the same coin
-
10.1089/ars.2010.3360, 20615076
-
Hausenloy DJ, Lecour S, Yellon DM. Reperfusion injury salvage kinase and survivor activating factor enhancement pro-survival signaling pathways in ischemic postconditioning: two sides of the same coin. Antioxid Redox Signal 2011, 14:893-907. 10.1089/ars.2010.3360, 20615076.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 893-907
-
-
Hausenloy, D.J.1
Lecour, S.2
Yellon, D.M.3
-
50
-
-
42049108814
-
Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury
-
10.1152/physrev.00024.2007, 3199571, 18391174
-
Murphy E, Steenbergen C. Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury. Physiol Rev 2008, 88:581-609. 10.1152/physrev.00024.2007, 3199571, 18391174.
-
(2008)
Physiol Rev
, vol.88
, pp. 581-609
-
-
Murphy, E.1
Steenbergen, C.2
-
51
-
-
33847642830
-
Obestatin mediated proliferation of human retinal pigment epithelial cells: regulatory mechanisms
-
10.1002/jcp.20925, 17186496
-
Camina JP, Campos JF, Caminos E, Dieguez C, Casanueva FF. Obestatin mediated proliferation of human retinal pigment epithelial cells: regulatory mechanisms. J Cell Physiol 2007, 211:1-9. 10.1002/jcp.20925, 17186496.
-
(2007)
J Cell Physiol
, vol.211
, pp. 1-9
-
-
Camina, J.P.1
Campos, J.F.2
Caminos, E.3
Dieguez, C.4
Casanueva, F.F.5
-
52
-
-
41449114267
-
Stimulation of extracellular signal-regulated kinases and proliferation in the human gastric cancer cells KATO-III by obestatin
-
Pazos Y, Alvarez CJ, Camina JP, Casanueva FF. Stimulation of extracellular signal-regulated kinases and proliferation in the human gastric cancer cells KATO-III by obestatin. Growth Factors 2008, 25:373-381.
-
(2008)
Growth Factors
, vol.25
, pp. 373-381
-
-
Pazos, Y.1
Alvarez, C.J.2
Camina, J.P.3
Casanueva, F.F.4
-
53
-
-
67649882599
-
Role of glycogen synthase kinase-3β in cardioprotection
-
10.1161/CIRCRESAHA.109.197996, 2726042, 19498210
-
Juhaszova M, Zorov DB, Yaniv Y, Nuss HB, Wang S, Sollott SJ. Role of glycogen synthase kinase-3β in cardioprotection. Circ Res 2009, 104(11):1240-1252. 10.1161/CIRCRESAHA.109.197996, 2726042, 19498210.
-
(2009)
Circ Res
, vol.104
, Issue.11
, pp. 1240-1252
-
-
Juhaszova, M.1
Zorov, D.B.2
Yaniv, Y.3
Nuss, H.B.4
Wang, S.5
Sollott, S.J.6
-
54
-
-
79960562931
-
Increased nitric oxide availability attenuates high fat diet metabolic alterations and gene expression associated with insulin resistance
-
10.1186/1475-2840-10-68, 3212914, 21781316
-
Razny U, Kiec-Wilk B, Wator L, Polus A, Dyduch G, Solnica B, Malecki M, Tomaszewska R, Cooke JP, Dembinska-Kiec A. Increased nitric oxide availability attenuates high fat diet metabolic alterations and gene expression associated with insulin resistance. Cardiovasc Diabetol 2011, 10:68. 10.1186/1475-2840-10-68, 3212914, 21781316.
-
(2011)
Cardiovasc Diabetol
, vol.10
, pp. 68
-
-
Razny, U.1
Kiec-Wilk, B.2
Wator, L.3
Polus, A.4
Dyduch, G.5
Solnica, B.6
Malecki, M.7
Tomaszewska, R.8
Cooke, J.P.9
Dembinska-Kiec, A.10
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