Size and sulfation are critical for the effect of heparin on APP processing and Aβ production

Journal of Neurochemistry

Volumn 123, Issue 3, 2012, Pages 447-457

  Cui, Hao ^a,b   Hung, Amos C ^a   Freeman, Craig ^c   Narkowicz, Christian ^b   Jacobson, Glenn A ^b   Small, David H ^a  

^a UNIVERSITY OF TASMANIA   (Australia)

^b UNIVERSITY OF TASMANIA   (Australia)

^c Biology and Environment   (Australia)

Author keywords

Alzheimer's disease; amyloid; glycosaminoglycan; sulfation

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CARBOXYL GROUP; GLYCOSAMINOGLYCAN; HEPARIN;

ANIMAL CELL; ARTICLE; BRAIN CELL; BRAIN CORTEX; CARBOHYDRATE ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; MOLECULAR SIZE; MOUSE; MOUSE STRAIN; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; SULFATION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANIMALS, NEWBORN; BLOOD-BRAIN BARRIER; DRUG DESIGN; HEPARIN; MICE; MICE, TRANSGENIC; NEURONS; PRIMARY CELL CULTURE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOGLYCANS;

MUS;

EID: 84867336210     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07929.x     Document Type: Article

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