-
2
-
-
13144306071
-
Genome-wide association studies for common diseases and complex traits
-
DOI 10.1038/nrg1521
-
Hirschhorn JN, Daly MJ 2005 Genome-wide association studies for common diseases and complex traits. Nat Rev Genet 6:95-108 (Pubitemid 40179532)
-
(2005)
Nature Reviews Genetics
, vol.6
, Issue.2
, pp. 95-108
-
-
Hirschhorn, J.N.1
Daly, M.J.2
-
3
-
-
33745279392
-
Evaluating and improving power in whole-genome association studies using fixed marker sets
-
DOI 10.1038/ng1816, PII N1816
-
Pe'er I, de Bakker PI, Maller J, Yelensky R, Altshuler D, Daly MJ 2006 Evaluating and improving power in whole-genome association studies using fixed marker sets. Nat Genet 38:663-667 (Pubitemid 43927308)
-
(2006)
Nature Genetics
, vol.38
, Issue.6
, pp. 663-667
-
-
Pe'er, I.1
De Bakker, P.I.W.2
Maller, J.3
Yelensky, R.4
Altshuler, D.5
Daly, M.J.6
-
4
-
-
0034973984
-
High-resolution multipoint linkage-disequilibrium mapping in the context of a human genome sequence
-
DOI 10.1086/321279
-
Rannala B, Reeve JP 2001 High-resolution multipoint linkage- disequilibrium mapping in the context of a human genome sequence. Am J Hum Genet 69:159-178 (Pubitemid 32614028)
-
(2001)
American Journal of Human Genetics
, vol.69
, Issue.1
, pp. 159-178
-
-
Rannala, B.1
Reeve, J.P.2
-
5
-
-
0035837267
-
Linkage disequilibrium in the human genome
-
DOI 10.1038/35075590
-
Reich DE, Cargill M, Bolk S, Ireland J, Sabeti PC, Richter DJ, Lavery T, Kouyoumjian R, Farhadian SF, Ward R, Lander ES 2001 Linkage disequilibrium in the human genome. Nature 411:199-204 (Pubitemid 32455179)
-
(2001)
Nature
, vol.411
, Issue.6834
, pp. 199-204
-
-
Reich, D.E.1
Cargili, M.2
Boik, S.3
Ireland, J.4
Sabeti, P.C.5
Richter, D.J.6
Lavery, T.7
Kouyoumjian, R.8
Farhadian, S.F.9
Ward, R.10
Lander, E.S.11
-
6
-
-
0035451780
-
On the allelic spectrum of human disease
-
DOI 10.1016/S0168-9525(01)02410-6, PII S0168952501024106
-
Reich DE, Lander ES 2001 On the allelic spectrum of human disease. Trends Genet 17:502-510 (Pubitemid 32763048)
-
(2001)
Trends in Genetics
, vol.17
, Issue.9
, pp. 502-510
-
-
Reich, D.E.1
Lander, E.S.2
-
7
-
-
35348983887
-
A second generation human haplotype map of over 3.1 million SNPs
-
Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, Belmont JW, Boudreau A, Hardenbol P, Leal SM, Pasternak S, Wheeler DA, Willis TD, Yu F, Yang H, Zeng C, Gao Y, Hu H, Hu W, Li C, Lin W, Liu S, Pan H, Tang X, Wang J, Wang W, Yu J, Zhang B, Zhang Q, Zhao H, Zhao H, Zhou J, Gabriel SB, Barry R, Blumenstiel B, Camargo A, Defelice M, Faggart M, Goyette M, Gupta S, Moore J, Nguyen H, Onofrio RC, et al. 2007 A second generation human haplotype map of over 3.1 million SNPs. Nature 449:851-861.
-
(2007)
Nature
, vol.449
, pp. 851-861
-
-
Frazer, K.A.1
Ballinger, D.G.2
Cox, D.R.3
Hinds, D.A.4
Stuve, L.L.5
Gibbs, R.A.6
Belmont, J.W.7
Boudreau, A.8
Hardenbol, P.9
Leal, S.M.10
Pasternak, S.11
Wheeler, D.A.12
Willis, T.D.13
Yu, F.14
Yang, H.15
Zeng, C.16
Gao, Y.17
Hu, H.18
Hu, W.19
Li, C.20
Lin, W.21
Liu, S.22
Pan, H.23
Tang, X.24
Wang, J.25
Wang, W.26
Yu, J.27
Zhang, B.28
Zhang, Q.29
Zhao, H.30
Zhao, H.31
Zhou, J.32
Gabriel, S.B.33
Barry, R.34
Blumenstiel, B.35
Camargo, A.36
Defelice, M.37
Faggart, M.38
Goyette, M.39
Gupta, S.40
Moore, J.41
Nguyen, H.42
Onofrio, R.C.43
more..
-
8
-
-
77956331627
-
Integrating common and rare genetic variation in diverse human populations
-
Altshuler DM, Gibbs RA, Peltonen L, Dermitzakis E, Schaffner SF, Yu F, Peltonen L, Dermitzakis E, Bonnen PE, Altshuler DM, Gibbs RA, de Bakker PI, Deloukas P, Gabriel SB, Gwilliam R, Hunt S, Inouye M, Jia X, Palotie A, Parkin M, Whittaker P, Yu F, Chang K, Hawes A, Lewis LR, Ren Y, Wheeler D, Gibbs RA, Muzny DM, Barnes C, Darvishi K, Hurles M, Korn JM, Kristiansson K, et al. 2010 Integrating common and rare genetic variation in diverse human populations. Nature 467:52-58
-
(2010)
Nature
, vol.467
, pp. 52-58
-
-
Altshuler, D.M.1
Gibbs, R.A.2
Peltonen, L.3
Dermitzakis, E.4
Schaffner, S.F.5
Yu, F.6
Peltonen, L.7
Dermitzakis, E.8
Bonnen, P.E.9
Altshuler, D.M.10
Gibbs, R.A.11
De Bakker, P.I.12
Deloukas, P.13
Gabriel, S.B.14
Gwilliam, R.15
Hunt, S.16
Inouye, M.17
Jia, X.18
Palotie, A.19
Parkin, M.20
Whittaker, P.21
Yu, F.22
Chang, K.23
Hawes, A.24
Lewis, L.R.25
Ren, Y.26
Wheeler, D.27
Gibbs, R.A.28
Muzny, D.M.29
Barnes, C.30
Darvishi, K.31
Hurles, M.32
Korn, J.M.33
Kristiansson, K.34
more..
-
9
-
-
84975742565
-
A map of human genome variation from population-scale sequencing
-
1000 Genomes Project Consortium
-
1000 Genomes Project Consortium 2010 A map of human genome variation from population-scale sequencing. Nature 467:1061-1073
-
(2010)
Nature
, vol.467
, pp. 1061-1073
-
-
-
10
-
-
78049360110
-
Genomics: In search of rare human variants
-
Nielsen R 2010 Genomics: in search of rare human variants. Nature 467:1050-1051
-
(2010)
Nature
, vol.467
, pp. 1050-1051
-
-
Nielsen, R.1
-
11
-
-
84863116742
-
A systematic survey of loss-of-function variants in human protein-coding genes
-
MacArthur DG, Balasubramanian S, Frankish A, Huang N, Morris J, Walter K, Jostins L, Habegger L, Pickrell JK, Montgomery SB, Albers CA, Zhang ZD, Conrad DF, Lunter G, Zheng H, Ayub Q, DePristo MA, Banks E, Hu M, Handsaker RE, Rosenfeld JA, Fromer M, Jin M, Mu XJ, Khurana E, Ye K, Kay M, Saunders GI, Suner MM, Hunt T, Barnes IH, Amid C, Carvalho-Silva DR, Bignell AH, Snow C, Yngvadottir B, Bumpstead S, Cooper DN, Xue Y, Romero IG, Wang J, Li Y, Gibbs RA, McCarroll SA, Dermitzakis ET, Pritchard JK, Barrett JC, Harrow J, Hurles ME, Gerstein MB, Tyler-Smith C 2012 A systematic survey of loss-of-function variants in human protein-coding genes. Science 335:823-828
-
(2012)
Science
, vol.335
, pp. 823-828
-
-
MacArthur, D.G.1
Balasubramanian, S.2
Frankish, A.3
Huang, N.4
Morris, J.5
Walter, K.6
Jostins, L.7
Habegger, L.8
Pickrell, J.K.9
Montgomery, S.B.10
Albers, C.A.11
Zhang, Z.D.12
Conrad, D.F.13
Lunter, G.14
Zheng, H.15
Ayub, Q.16
DePristo, M.A.17
Banks, E.18
Hu, M.19
Handsaker, R.E.20
Rosenfeld, J.A.21
Fromer, M.22
Jin, M.23
Mu, X.J.24
Khurana, E.25
Ye, K.26
Kay, M.27
Saunders, G.I.28
Suner, M.M.29
Hunt, T.30
Barnes, I.H.31
Amid, C.32
Carvalho-Silva, D.R.33
Bignell, A.H.34
Snow, C.35
Yngvadottir, B.36
Bumpstead, S.37
Cooper, D.N.38
Xue, Y.39
Romero, I.G.40
Wang, J.41
Li, Y.42
Gibbs, R.A.43
McCarroll, S.A.44
Dermitzakis, E.T.45
Pritchard, J.K.46
Barrett, J.C.47
Harrow, J.48
Hurles, M.E.49
Gerstein, M.B.50
Tyler-Smith, C.51
more..
-
12
-
-
78049412267
-
Diversity of human copy number variation and multicopy genes
-
Sudmant PH, Kitzman JO, Antonacci F, Alkan C, Malig M, Tsalenko A, Sampas N, Bruhn L, Shendure J, Eichler EE 2010 Diversity of human copy number variation and multicopy genes. Science 330:641-646
-
(2010)
Science
, vol.330
, pp. 641-646
-
-
Sudmant, P.H.1
Kitzman, J.O.2
Antonacci, F.3
Alkan, C.4
Malig, M.5
Tsalenko, A.6
Sampas, N.7
Bruhn, L.8
Shendure, J.9
Eichler, E.E.10
-
13
-
-
18144425478
-
A genome-wide scalable SNP genotyping assay using microarray technology
-
DOI 10.1038/ng1547
-
Gunderson KL, Steemers FJ, Lee G, Mendoza LG, Chee MS 2005 A genome-wide scalable SNP genotyping assay using microarray technology. Nat Genet 37:549-554 (Pubitemid 40617286)
-
(2005)
Nature Genetics
, vol.37
, Issue.5
, pp. 549-554
-
-
Gunderson, K.L.1
Steemers, F.J.2
Lee, G.3
Mendoza, L.G.4
Chee, M.S.5
-
14
-
-
70350220595
-
Genotyping technologies for genetic research
-
Ragoussis J 2009 Genotyping technologies for genetic research. Annu Rev Genomics Hum Genet 10:117-133
-
(2009)
Annu Rev Genomics Hum Genet
, vol.10
, pp. 117-133
-
-
Ragoussis, J.1
-
15
-
-
78649508578
-
MaCH: Using sequence and genotype data to estimate haplotypes and unobserved genotypes
-
Li Y, Willer CJ, Ding J, Scheet P, Abecasis GR 2010 MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet Epidemiol 34:816-834
-
(2010)
Genet Epidemiol
, vol.34
, pp. 816-834
-
-
Li, Y.1
Willer, C.J.2
Ding, J.3
Scheet, P.4
Abecasis, G.R.5
-
16
-
-
34347344976
-
A new multipoint method for genome-wide association studies by imputation of genotypes
-
DOI 10.1038/ng2088, PII NG2088
-
Marchini J, Howie B, Myers S, McVean G, Donnelly P 2007 A new multipoint method for genome-wide association studies by imputation of genotypes. Nat Genet 39:906-913 (Pubitemid 47014502)
-
(2007)
Nature Genetics
, vol.39
, Issue.7
, pp. 906-913
-
-
Marchini, J.1
Howie, B.2
Myers, S.3
McVean, G.4
Donnelly, P.5
-
17
-
-
27644439141
-
Efficiency and power in genetic association studies
-
DOI 10.1038/ng1669, PII N1669
-
de Bakker PI, Yelensky R, Pe'er I, Gabriel SB, Daly MJ, Altshuler D 2005 Efficiency and power in genetic association studies. Nat Genet 37:1217-1223 (Pubitemid 41568704)
-
(2005)
Nature Genetics
, vol.37
, Issue.11
, pp. 1217-1223
-
-
De Bakker, P.I.W.1
Yelensky, R.2
Pe'Er, I.3
Gabriel, S.B.4
Daly, M.J.5
Altshuler, D.6
-
18
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, Manolio TA 2009 Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci USA 106:9362-9367
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
Collins, F.S.6
Manolio, T.A.7
-
19
-
-
35748963239
-
Genome-wide association with bone mass and geometry in the Framingham Heart Study
-
Kiel DP, Demissie S, Dupuis J, Lunetta KL, Murabito JM, Karasik D 2007 Genome-wide association with bone mass and geometry in the Framingham Heart Study. BMC Med Genet 8(Suppl 1):S14
-
(2007)
BMC Med Genet
, vol.8
, Issue.SUPPL. 1
-
-
Kiel, D.P.1
Demissie, S.2
Dupuis, J.3
Lunetta, K.L.4
Murabito, J.M.5
Karasik, D.6
-
20
-
-
44349167229
-
Multiple genetic loci for bone mineral density and fractures
-
DOI 10.1056/NEJMoa0801197
-
Styrkarsdottir U, Halldorsson BV, Gretarsdottir S, Gudbjartsson DF, Walters GB, Ingvarsson T, Jonsdottir T, Saemundsdottir J, Center JR, Nguyen TV, Bagger Y, Gulcher JR, Eisman JA, Christiansen C, Sigurdsson G, Kong A, Thorsteinsdottir U, Stefansson K 2008 Multiple genetic loci for bone mineral density and fractures. N Engl J Med 358:2355-2365 (Pubitemid 351749159)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.22
, pp. 2355-2365
-
-
Styrkarsdottir, U.1
Halldorsson, B.V.2
Gretarsdottir, S.3
Gudbjartsson, D.F.4
Walters, G.B.5
Ingvarsson, T.6
Jonsdottir, T.7
Saemundsdottir, J.8
Center, J.R.9
Nguyen, T.V.10
Bagger, Y.11
Gulcher, J.R.12
Eisman, J.A.13
Christiansen, C.14
Sigurdsson, G.15
Kong, A.16
Thorsteinsdottir, U.17
Stefansson, K.18
-
21
-
-
58149145443
-
New sequence variants associated with bone mineral density
-
Styrkarsdottir U, Halldorsson BV, Gretarsdottir S, Gudbjartsson DF, Walters GB, Ingvarsson T, Jonsdottir T, Saemundsdottir J, Snorradóttir S, Center JR, Nguyen TV, Alexandersen P, Gulcher JR, Eisman JA, Christiansen C, Sigurdsson G, Kong A, Thorsteinsdottir U, Stefansson K 2009 New sequence variants associated with bone mineral density. Nat Genet 41:15-17
-
(2009)
Nat Genet
, vol.41
, pp. 15-17
-
-
Styrkarsdottir, U.1
Halldorsson, B.V.2
Gretarsdottir, S.3
Gudbjartsson, D.F.4
Walters, G.B.5
Ingvarsson, T.6
Jonsdottir, T.7
Saemundsdottir, J.8
Snorradóttir, S.9
Center, J.R.10
Nguyen, T.V.11
Alexandersen, P.12
Gulcher, J.R.13
Eisman, J.A.14
Christiansen, C.15
Sigurdsson, G.16
Kong, A.17
Thorsteinsdottir, U.18
Stefansson, K.19
-
22
-
-
61849164536
-
Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups
-
Xiong DH, Liu XG, Guo YF, Tan LJ, Wang L, Sha BY, Tang ZH, Pan F, Yang TL, Chen XD, Lei SF, Yerges LM, Zhu XZ, Wheeler VW, Patrick AL, Bunker CH, Guo Y, Yan H, Pei YF, Zhang YP, Levy S, Papasian CJ, Xiao P, Lundberg YW, Recker RR, Liu YZ, Liu YJ, Zmuda JM, Deng HW 2009 Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups. Am J Hum Genet 84:388-398
-
(2009)
Am J Hum Genet
, vol.84
, pp. 388-398
-
-
Xiong, D.H.1
Liu, X.G.2
Guo, Y.F.3
Tan, L.J.4
Wang, L.5
Sha, B.Y.6
Tang, Z.H.7
Pan, F.8
Yang, T.L.9
Chen, X.D.10
Lei, S.F.11
Yerges, L.M.12
Zhu, X.Z.13
Wheeler, V.W.14
Patrick, A.L.15
Bunker, C.H.16
Guo, Y.17
Yan, H.18
Pei, Y.F.19
Zhang, Y.P.20
Levy, S.21
Papasian, C.J.22
Xiao, P.23
Lundberg, Y.W.24
Recker, R.R.25
Liu, Y.Z.26
Liu, Y.J.27
Zmuda, J.M.28
Deng, H.W.29
more..
-
23
-
-
43049181624
-
Bone mineral density, osteoporosis, and osteoporotic fractures: A genome-wide association study
-
Richards JB, Rivadeneira F, Inouye M, Pastinen TM, Soranzo N, Wilson SG, Andrew T, Falchi M, Gwilliam R, Ahmadi KR, Valdes AM, Arp P, Whittaker P, Verlaan DJ, Jhamai M, Kumanduri V, Moorhouse M, van Meurs JB, Hofman A, Pols HA, Hart D, Zhai G, Kato BS, Mullin BH, Zhang F, Deloukas P, Uitterlinden AG, Spector TD 2008 Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study. Lancet 371:1505-1512
-
(2008)
Lancet
, vol.371
, pp. 1505-1512
-
-
Richards, J.B.1
Rivadeneira, F.2
Inouye, M.3
Pastinen, T.M.4
Soranzo, N.5
Wilson, S.G.6
Andrew, T.7
Falchi, M.8
Gwilliam, R.9
Ahmadi, K.R.10
Valdes, A.M.11
Arp, P.12
Whittaker, P.13
Verlaan, D.J.14
Jhamai, M.15
Kumanduri, V.16
Moorhouse, M.17
Van Meurs, J.B.18
Hofman, A.19
Pols, H.A.20
Hart, D.21
Zhai, G.22
Kato, B.S.23
Mullin, B.H.24
Zhang, F.25
Deloukas, P.26
Uitterlinden, A.G.27
Spector, T.D.28
more..
-
24
-
-
77951645281
-
Genome-wide association study of bone mineral density in premenopausal European-American women and replication in African-American women
-
Koller DL, Ichikawa S, Lai D, Padgett LR, Doheny KF, Pugh E, Paschall J, Hui SL, Edenberg HJ, Xuei X, Peacock M, Econs MJ, Foroud T 2010 Genome-wide association study of bone mineral density in premenopausal European-American women and replication in African-American women. J Clin Endocrinol Metab 95:1802-1809
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 1802-1809
-
-
Koller, D.L.1
Ichikawa, S.2
Lai, D.3
Padgett, L.R.4
Doheny, K.F.5
Pugh, E.6
Paschall, J.7
Hui, S.L.8
Edenberg, H.J.9
Xuei, X.10
Peacock, M.11
Econs, M.J.12
Foroud, T.13
-
25
-
-
76249108602
-
Association of JAG1 with bone mineral density and osteoporotic fractures: A genome-wide association study and follow-up replication studies
-
Kung AW, Xiao SM, Cherny S, Li GH, Gao Y, Tso G, Lau KS, Luk KD, Liu JM, Cui B, Zhang MJ, Zhang ZL, He JW, Yue H, Xia WB, Luo LM, He SL, Kiel DP, Karasik D, Hsu YH, Cupples LA, Demissie S, Styrkarsdottir U, Halldorsson BV, Sigurdsson G, Thorsteinsdottir U, Stefansson K, Richards JB, Zhai G, Soranzo N, Valdes A, Spector TD, Sham PC 2010 Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies. Am J Hum Genet 86:229-239
-
(2010)
Am J Hum Genet
, vol.86
, pp. 229-239
-
-
Kung, A.W.1
Xiao, S.M.2
Cherny, S.3
Li, G.H.4
Gao, Y.5
Tso, G.6
Lau, K.S.7
Luk, K.D.8
Liu, J.M.9
Cui, B.10
Zhang, M.J.11
Zhang, Z.L.12
He, J.W.13
Yue, H.14
Xia, W.B.15
Luo, L.M.16
He, S.L.17
Kiel, D.P.18
Karasik, D.19
Hsu, Y.H.20
Cupples, L.A.21
Demissie, S.22
Styrkarsdottir, U.23
Halldorsson, B.V.24
Sigurdsson, G.25
Thorsteinsdottir, U.26
Stefansson, K.27
Richards, J.B.28
Zhai, G.29
Soranzo, N.30
Valdes, A.31
Spector, T.D.32
Sham, P.C.33
more..
-
26
-
-
77954157408
-
An integration of genomewide association study and gene expression profiling to prioritize the discovery of novel susceptibility loci for osteoporosis-related traits
-
Hsu YH, Zillikens MC, Wilson SG, Farber CR, Demissie S, Soranzo N, Bianchi EN, Grundberg E, Liang L, Richards JB, Estrada K, Zhou Y, van Nas A, Moffatt MF, Zhai G, Hofman A, van Meurs JB, Pols HA, Price RI, Nilsson O, Pastinen T, Cupples LA, Lusis AJ, Schadt EE, Ferrari S, Uitterlinden AG, Rivadeneira F, Spector TD, Karasik D, Kiel DP 2010 An integration of genomewide association study and gene expression profiling to prioritize the discovery of novel susceptibility loci for osteoporosis-related traits. PLoS Genet 6:e1000977
-
(2010)
PLoS Genet
, vol.6
-
-
Hsu, Y.H.1
Zillikens, M.C.2
Wilson, S.G.3
Farber, C.R.4
Demissie, S.5
Soranzo, N.6
Bianchi, E.N.7
Grundberg, E.8
Liang, L.9
Richards, J.B.10
Estrada, K.11
Zhou, Y.12
Van Nas, A.13
Moffatt, M.F.14
Zhai, G.15
Hofman, A.16
Van Meurs, J.B.17
Pols, H.A.18
Price, R.I.19
Nilsson, O.20
Pastinen, T.21
Cupples, L.A.22
Lusis, A.J.23
Schadt, E.E.24
Ferrari, S.25
Uitterlinden, A.G.26
Rivadeneira, F.27
Spector, T.D.28
Karasik, D.29
Kiel, D.P.30
more..
-
27
-
-
70350646912
-
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies
-
Rivadeneira F, Styrkársdottir U, Estrada K, Halldórsson BV, Hsu YH, Richards JB, Zillikens MC, Kavvoura FK, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Grundberg E, Hofman A, Kong A, Karasik D, van Meurs JB, Oostra B, Pastinen T, Pols HA, Sigurdsson G, Soranzo N, Thorleifsson G, Thorsteinsdottir U, Williams FM, Wilson SG, Zhou Y, Ralston SH, van Duijn CM, Spector T, Kiel DP, Stefansson K, Ioannidis JP, Uitterlinden AG 2009 Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet 41:1199-1206
-
(2009)
Nat Genet
, vol.41
, pp. 1199-1206
-
-
Rivadeneira, F.1
Styrkársdottir, U.2
Estrada, K.3
Halldórsson, B.V.4
Hsu, Y.H.5
Richards, J.B.6
Zillikens, M.C.7
Kavvoura, F.K.8
Amin, N.9
Aulchenko, Y.S.10
Cupples, L.A.11
Deloukas, P.12
Demissie, S.13
Grundberg, E.14
Hofman, A.15
Kong, A.16
Karasik, D.17
Van Meurs, J.B.18
Oostra, B.19
Pastinen, T.20
Pols, H.A.21
Sigurdsson, G.22
Soranzo, N.23
Thorleifsson, G.24
Thorsteinsdottir, U.25
Williams, F.M.26
Wilson, S.G.27
Zhou, Y.28
Ralston, S.H.29
Van Duijn, C.M.30
Spector, T.31
Kiel, D.P.32
Stefansson, K.33
Ioannidis, J.P.34
Uitterlinden, A.G.35
more..
-
28
-
-
79955578829
-
Genomewide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk
-
Duncan EL, Danoy P, Kemp JP, Leo PJ, McCloskey E, Nicholson GC, Eastell R, Prince RL, Eisman JA, Jones G, Sambrook PN, Reid IR, Dennison EM, Wark J, Richards JB, Uitterlinden AG, Spector TD, Esapa C, Cox RD, Brown SD, Thakker RV, Addison KA, Bradbury LA, Center JR, Cooper C, Cremin C, Estrada K, Felsenberg D, Glüer CC, Hadler J, Henry MJ, Hofman A, Kotowicz MA, Makovey J, Nguyen SC, Nguyen TV, Pasco JA, Pryce K, Reid DM, Rivadeneira F, Roux C, Stefansson K, Styrkarsdottir U, Thorleifsson G, Tichawangana R, Evans DM, Brown MA 2011 Genomewide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk. PLoS Genet 7:e1001372
-
(2011)
PLoS Genet
, vol.7
-
-
Duncan, E.L.1
Danoy, P.2
Kemp, J.P.3
Leo, P.J.4
McCloskey, E.5
Nicholson, G.C.6
Eastell, R.7
Prince, R.L.8
Eisman, J.A.9
Jones, G.10
Sambrook, P.N.11
Reid, I.R.12
Dennison, E.M.13
Wark, J.14
Richards, J.B.15
Uitterlinden, A.G.16
Spector, T.D.17
Esapa, C.18
Cox, R.D.19
Brown, S.D.20
Thakker, R.V.21
Addison, K.A.22
Bradbury, L.A.23
Center, J.R.24
Cooper, C.25
Cremin, C.26
Estrada, K.27
Felsenberg, D.28
Glüer, C.C.29
Hadler, J.30
Henry, M.J.31
Hofman, A.32
Kotowicz, M.A.33
Makovey, J.34
Nguyen, S.C.35
Nguyen, T.V.36
Pasco, J.A.37
Pryce, K.38
Reid, D.M.39
Rivadeneira, F.40
Roux, C.41
Stefansson, K.42
Styrkarsdottir, U.43
Thorleifsson, G.44
Tichawangana, R.45
Evans, D.M.46
Brown, M.A.47
more..
-
29
-
-
79955788680
-
Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese
-
Kou I, Takahashi A, Urano T, Fukui N, Ito H, Ozaki K, Tanaka T, Hosoi T, Shiraki M, Inoue S, Nakamura Y, Kamatani N, Kubo M, Mori S, Ikegawa S 2011 Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese. PLoS One 6:e19641
-
(2011)
PLoS One
, vol.6
-
-
Kou, I.1
Takahashi, A.2
Urano, T.3
Fukui, N.4
Ito, H.5
Ozaki, K.6
Tanaka, T.7
Hosoi, T.8
Shiraki, M.9
Inoue, S.10
Nakamura, Y.11
Kamatani, N.12
Kubo, M.13
Mori, S.14
Ikegawa, S.15
-
30
-
-
84860331458
-
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
-
Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, Vandenput L, Willner D, Xiao SM, Yerges-Armstrong LM, Zheng HF, Alonso N, Eriksson J, Kammerer CM, Kaptoge SK, Leo PJ, Thorleifsson G, Wilson SG, Wilson JF, Aalto V, Alen M, Aragaki AK, Aspelund T, Center JR, Dailiana Z, Duggan DJ, Garcia M, et al. 2012 Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet 44:491-501
-
(2012)
Nat Genet
, vol.44
, pp. 491-501
-
-
Estrada, K.1
Styrkarsdottir, U.2
Evangelou, E.3
Hsu, Y.H.4
Duncan, E.L.5
Ntzani, E.E.6
Oei, L.7
Albagha, O.M.8
Amin, N.9
Kemp, J.P.10
Koller, D.L.11
Li, G.12
Liu, C.T.13
Minster, R.L.14
Moayyeri, A.15
Vandenput, L.16
Willner, D.17
Xiao, S.M.18
Yerges-Armstrong, L.M.19
Zheng, H.F.20
Alonso, N.21
Eriksson, J.22
Kammerer, C.M.23
Kaptoge, S.K.24
Leo, P.J.25
Thorleifsson, G.26
Wilson, S.G.27
Wilson, J.F.28
Aalto, V.29
Alen, M.30
Aragaki, A.K.31
Aspelund, T.32
Center, J.R.33
Dailiana, Z.34
Duggan, D.J.35
Garcia, M.36
more..
-
31
-
-
77953523922
-
IL21R and PTH may underlie variation of femoral neck bone mineral density as revealed by a genome-wide association study
-
Guo Y, Zhang LS, Yang TL, Tian Q, Xiong DH, Pei YF, Deng HW 2010 IL21R and PTH may underlie variation of femoral neck bone mineral density as revealed by a genome-wide association study. J Bone Miner Res 25:1042-1048
-
(2010)
J Bone Miner Res
, vol.25
, pp. 1042-1048
-
-
Guo, Y.1
Zhang, L.S.2
Yang, T.L.3
Tian, Q.4
Xiong, D.H.5
Pei, Y.F.6
Deng, H.W.7
-
32
-
-
64549163221
-
Common variants in the region around Osterix are associated with bone mineral density and growth in childhood
-
Timpson NJ, Tobias JH, Richards JB, Soranzo N, Duncan EL, Sims AM, Whittaker P, Kumanduri V, Zhai G, Glaser B, Eisman J, Jones G, Nicholson G, Prince R, Seeman E, Spector TD, Brown MA, Peltonen L, Smith GD, Deloukas P, Evans DM 2009 Common variants in the region around Osterix are associated with bone mineral density and growth in childhood. Hum Mol Genet 18: 1510-1517
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1510-1517
-
-
Timpson, N.J.1
Tobias, J.H.2
Richards, J.B.3
Soranzo, N.4
Duncan, E.L.5
Sims, A.M.6
Whittaker, P.7
Kumanduri, V.8
Zhai, G.9
Glaser, B.10
Eisman, J.11
Jones, G.12
Nicholson, G.13
Prince, R.14
Seeman, E.15
Spector, T.D.16
Brown, M.A.17
Peltonen, L.18
Smith, G.D.19
Deloukas, P.20
Evans, D.M.21
more..
-
33
-
-
78649582946
-
A genome-wide association analysis implicates SOX6 as a candidate gene for wrist bone mass
-
Tan L, Liu R, Lei S, Pan R, Yang T, Yan H, Pei Y, Yang F, Zhang F, Pan F, Zhang Y, Hu H, Levy S, Deng H 2010 A genome-wide association analysis implicates SOX6 as a candidate gene for wrist bone mass. Sci China Life Sci 53:1065-1072
-
(2010)
Sci China Life Sci
, vol.53
, pp. 1065-1072
-
-
Tan, L.1
Liu, R.2
Lei, S.3
Pan, R.4
Yang, T.5
Yan, H.6
Pei, Y.7
Yang, F.8
Zhang, F.9
Pan, F.10
Zhang, Y.11
Hu, H.12
Levy, S.13
Deng, H.14
-
34
-
-
67349188883
-
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits
-
Cho YS, Go MJ, Kim YJ, Heo JY, Oh JH, Ban HJ, Yoon D, Lee MH, Kim DJ, Park M, Cha SH, Kim JW, Han BG, Min H, Ahn Y, Park MS, Han HR, Jang HY, Cho EY, Lee JE, Cho NH, Shin C, Park T, Park JW, Lee JK, Cardon L, Clarke G, McCarthy MI, Lee JY, Lee JK, Oh B, Kim HL 2009 A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Nat Genet 41:527-534
-
(2009)
Nat Genet
, vol.41
, pp. 527-534
-
-
Cho, Y.S.1
Go, M.J.2
Kim, Y.J.3
Heo, J.Y.4
Oh, J.H.5
Ban, H.J.6
Yoon, D.7
Lee, M.H.8
Kim, D.J.9
Park, M.10
Cha, S.H.11
Kim, J.W.12
Han, B.G.13
Min, H.14
Ahn, Y.15
Park, M.S.16
Han, H.R.17
Jang, H.Y.18
Cho, E.Y.19
Lee, J.E.20
Cho, N.H.21
Shin, C.22
Park, T.23
Park, J.W.24
Lee, J.K.25
Cardon, L.26
Clarke, G.27
McCarthy, M.I.28
Lee, J.Y.29
Lee, J.K.30
Oh, B.31
Kim, H.L.32
more..
-
35
-
-
78649692094
-
Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone
-
Paternoster L, Lorentzon M, Vandenput L, Karlsson MK, Ljunggren O, Kindmark A, Mellstrom D, Kemp JP, Jarett CE, Holly JM, Sayers A, St Pourcain B, Timpson NJ, Deloukas P, Davey Smith G, Ring SM, Evans DM, Tobias JH, Ohlsson C 2010 Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone. PLoS Genet 6:e1001217
-
(2010)
PLoS Genet
, vol.6
-
-
Paternoster, L.1
Lorentzon, M.2
Vandenput, L.3
Karlsson, M.K.4
Ljunggren, O.5
Kindmark, A.6
Mellstrom, D.7
Kemp, J.P.8
Jarett, C.E.9
Holly, J.M.10
Sayers, A.11
St Pourcain, B.12
Timpson, N.J.13
Deloukas, P.14
Davey Smith, G.15
Ring, S.M.16
Evans, D.M.17
Tobias, J.H.18
Ohlsson, C.19
-
36
-
-
52349086806
-
Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study
-
Liu YZ, Wilson SG, Wang L, Liu XG, Guo YF, Li J, Yan H, Deloukas P, Soranzo N, Chinappen-Horsley U, Cervino A, Williams FM, Xiong DH, Zhang YP, Jin TB, Levy S, Papasian CJ, Drees BM, Hamilton JJ, Recker RR, Spector TD, Deng HW 2008 Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study. PLoS One 3:e3160
-
(2008)
PLoS One
, vol.3
-
-
Liu, Y.Z.1
Wilson, S.G.2
Wang, L.3
Liu, X.G.4
Guo, Y.F.5
Li, J.6
Yan, H.7
Deloukas, P.8
Soranzo, N.9
Chinappen-Horsley, U.10
Cervino, A.11
Williams, F.M.12
Xiong, D.H.13
Zhang, Y.P.14
Jin, T.B.15
Levy, S.16
Papasian, C.J.17
Drees, B.M.18
Hamilton, J.J.19
Recker, R.R.20
Spector, T.D.21
Deng, H.W.22
more..
-
37
-
-
77953419885
-
Genome-wide association study for femoral neck bone geometry
-
Zhao LJ, Liu XG, Liu YZ, Liu YJ, Papasian CJ, Sha BY, Pan F, Guo YF, Wang L, Yan H, Xiong DH, Tang ZH, Yang TL, Chen XD, Guo Y, Li J, Shen H, Zhang F, Lei SF, Recker RR, Deng HW 2010 Genome-wide association study for femoral neck bone geometry. J Bone Miner Res 25:320-329
-
(2010)
J Bone Miner Res
, vol.25
, pp. 320-329
-
-
Zhao, L.J.1
Liu, X.G.2
Liu, Y.Z.3
Liu, Y.J.4
Papasian, C.J.5
Sha, B.Y.6
Pan, F.7
Guo, Y.F.8
Wang, L.9
Yan, H.10
Xiong, D.H.11
Tang, Z.H.12
Yang, T.L.13
Chen, X.D.14
Guo, Y.15
Li, J.16
Shen, H.17
Zhang, F.18
Lei, S.F.19
Recker, R.R.20
Deng, H.W.21
more..
-
38
-
-
76749119927
-
Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis
-
Guo Y, Tan LJ, Lei SF, Yang TL, Chen XD, Zhang F, Chen Y, Pan F, Yan H, Liu X, Tian Q, Zhang ZX, Zhou Q, Qiu C, Dong SS, Xu XH, Guo YF, Zhu XZ, Liu SL, Wang XL, Li X, Luo Y, Zhang LS, Li M, Wang JT, Wen T, Drees B, Hamilton J, Papasian CJ, Recker RR, Song XP, Cheng J, Deng HW 2010 Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis. PLoS Genet 6:e1000806
-
(2010)
PLoS Genet
, vol.6
-
-
Guo, Y.1
Tan, L.J.2
Lei, S.F.3
Yang, T.L.4
Chen, X.D.5
Zhang, F.6
Chen, Y.7
Pan, F.8
Yan, H.9
Liu, X.10
Tian, Q.11
Zhang, Z.X.12
Zhou, Q.13
Qiu, C.14
Dong, S.S.15
Xu, X.H.16
Guo, Y.F.17
Zhu, X.Z.18
Liu, S.L.19
Wang, X.L.20
Li, X.21
Luo, Y.22
Zhang, L.S.23
Li, M.24
Wang, J.T.25
Wen, T.26
Drees, B.27
Hamilton, J.28
Papasian, C.J.29
Recker, R.R.30
Song, X.P.31
Cheng, J.32
Deng, H.W.33
more..
-
39
-
-
77952884683
-
Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone
-
Albagha OM, Visconti MR, Alonso N, Langston AL, Cundy T, Dargie R, Dunlop MG, Fraser WD, Hooper MJ, Isaia G, Nicholson GC, del Pino Montes J, Gonzalez-Sarmiento R, di Stefano M, Tenesa A, Walsh JP, Ralston SH 2010 Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone. Nat Genet 42:520-524
-
(2010)
Nat Genet
, vol.42
, pp. 520-524
-
-
Albagha, O.M.1
Visconti, M.R.2
Alonso, N.3
Langston, A.L.4
Cundy, T.5
Dargie, R.6
Dunlop, M.G.7
Fraser, W.D.8
Hooper, M.J.9
Isaia, G.10
Nicholson, G.C.11
Del Pino Montes, J.12
Gonzalez-Sarmiento, R.13
Di Stefano, M.14
Tenesa, A.15
Walsh, J.P.16
Ralston, S.H.17
-
40
-
-
79959745220
-
Genome-wide association identifies three new susceptibility loci for Paget's disease of bone
-
Albagha OM, Wani SE, Visconti MR, Alonso N, Goodman K, Brandi ML, Cundy T, Chung PY, Dargie R, Devogelaer JP, Falchetti A, Fraser WD, Gennari L, Gianfrancesco F, Hooper MJ, Van Hul W, Isaia G, Nicholson GC, Nuti R, Papapoulos S, Montes Jdel P, Ratajczak T, Rea SL, Rendina D, Gonzalez-Sarmiento R, Di Stefano M, Ward LC, Walsh JP, Ralston SH 2011 Genome-wide association identifies three new susceptibility loci for Paget's disease of bone. Nat Genet 43:685-689
-
(2011)
Nat Genet
, vol.43
, pp. 685-689
-
-
Albagha, O.M.1
Wani, S.E.2
Visconti, M.R.3
Alonso, N.4
Goodman, K.5
Brandi, M.L.6
Cundy, T.7
Chung, P.Y.8
Dargie, R.9
Devogelaer, J.P.10
Falchetti, A.11
Fraser, W.D.12
Gennari, L.13
Gianfrancesco, F.14
Hooper, M.J.15
Van Hul, W.16
Isaia, G.17
Nicholson, G.C.18
Nuti, R.19
Papapoulos, S.20
Montes, J.D.P.21
Ratajczak, T.22
Rea, S.L.23
Rendina, D.24
Gonzalez-Sarmiento, R.25
Di Stefano, M.26
Ward, L.C.27
Walsh, J.P.28
Ralston, S.H.29
more..
-
41
-
-
84858023800
-
Learning from our GWAS mistakes: From experimental design to scientific method
-
Lambert CG, Black LJ 2012 Learning from our GWAS mistakes: from experimental design to scientific method. Biostatistics 13:195-203
-
(2012)
Biostatistics
, vol.13
, pp. 195-203
-
-
Lambert, C.G.1
Black, L.J.2
-
42
-
-
79960666840
-
Retraction
-
Sebastiani P, Solovieff N, Puca A, Hartley SW, Milista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Perls TT 2011 Retraction. Science 330:404
-
(2011)
Science
, vol.330
, pp. 404
-
-
Sebastiani, P.1
Solovieff, N.2
Puca, A.3
Hartley, S.W.4
Milista, E.5
Andersen, S.6
Dworkis, D.A.7
Wilk, J.B.8
Myers, R.H.9
Steinberg, M.H.10
Montano, M.11
Baldwin, C.T.12
Perls, T.T.13
-
43
-
-
0038192128
-
Effects of population structure and admixture on exact tests for association between loci
-
Law B, Buckleton JS, Triggs CM, Weir BS 2003 Effects of population structure and admixture on exact tests for association between loci. Genetics 164:381-387 (Pubitemid 36617721)
-
(2003)
Genetics
, vol.164
, Issue.1
, pp. 381-387
-
-
Law, B.1
Buckleton, J.S.2
Triggs, C.M.3
Weir, B.S.4
-
44
-
-
0041817568
-
Inference of population structure using multilocus genotype data: Linked loci and correlated allele frequencies
-
Falush D, Stephens M, Pritchard JK 2003 Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics 164:1567-1587 (Pubitemid 37102217)
-
(2003)
Genetics
, vol.164
, Issue.4
, pp. 1567-1587
-
-
Falush, D.1
Stephens, M.2
Pritchard, J.K.3
-
45
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
DOI 10.1038/ng1847, PII NG1847
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D 2006 Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 38:904-909 (Pubitemid 44141658)
-
(2006)
Nature Genetics
, vol.38
, Issue.8
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
46
-
-
0032714352
-
Genomic control for association studies
-
Devlin B, Roeder K 1999 Genomic control for association studies. Biometrics 55:997-1004
-
(1999)
Biometrics
, vol.55
, pp. 997-1004
-
-
Devlin, B.1
Roeder, K.2
-
47
-
-
16544380910
-
Genomic control to the extreme
-
author reply 1131
-
Devlin B, Bacanu SA, Roeder K 2004 Genomic control to the extreme. Nat Genet 36:1129-1130; author reply 1131
-
(2004)
Nat Genet
, vol.36
, pp. 1129-1130
-
-
Devlin, B.1
Bacanu, S.A.2
Roeder, K.3
-
48
-
-
33745279056
-
Evaluating coverage of genome-wide association studies
-
DOI 10.1038/ng1801, PII N1801
-
Barrett JC, Cardon LR 2006 Evaluating coverage of genome-wide association studies. Nat Genet 38:659-662 (Pubitemid 43927307)
-
(2006)
Nature Genetics
, vol.38
, Issue.6
, pp. 659-662
-
-
Barrett, J.C.1
Cardon, L.R.2
-
49
-
-
0038621500
-
Molecular studies of identification of genes for osteoporosis: The 2002 update
-
DOI 10.1677/joe.0.1770147
-
Liu YZ, Liu YJ, Recker RR, Deng HW 2003 Molecular studies of identification of genes for osteoporosis: the 2002 update. J Endocrinol 177:147-196 (Pubitemid 36665294)
-
(2003)
Journal of Endocrinology
, vol.177
, Issue.2
, pp. 147-196
-
-
Liu, Y.-Z.1
Liu, Y.-J.2
Recker, R.R.3
Deng, H.-W.4
-
50
-
-
33745612144
-
Molecular genetic studies of gene identification for osteoporosis: A 2004 update
-
DOI 10.1359/jbmr.051002
-
Liu YJ, Shen H, Xiao P, Xiong DH, Li LH, Recker RR, Deng HW 2006 Molecular genetic studies of gene identification for osteoporosis: a 2004 update. J Bone Miner Res 21:1511-1535 (Pubitemid 44484596)
-
(2006)
Journal of Bone and Mineral Research
, vol.21
, Issue.10
, pp. 1511-1535
-
-
Liu, Y.-J.1
Shen, H.2
Xiao, P.3
Xiong, D.-H.4
Li, L.-H.5
Recker, R.R.6
Deng, H.-W.7
-
51
-
-
70350221000
-
Collaborative meta-analysis: Associations of 150 candidate genes with osteoporosis and osteoporotic fracture
-
Richards JB, Kavvoura FK, Rivadeneira F, Styrkársdóttir U, Estrada K, Halldórsson BV, Hsu YH, Zillikens MC, Wilson SG, Mullin BH, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Hofman A, Kong A, Karasik D, van Meurs JB, Oostra BA, Pols HA, Sigurdsson G, Thorsteinsdottir U, Soranzo N, Williams FM, Zhou Y, Ralston SH, Thorleifsson G, van Duijn CM, Kiel DP, Stefansson K, Uitterlinden AG, Ioannidis JP, Spector TD 2009 Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med 151: 528-537
-
(2009)
Ann Intern Med
, vol.151
, pp. 528-537
-
-
Richards, J.B.1
Kavvoura, F.K.2
Rivadeneira, F.3
Styrkársdóttir, U.4
Estrada, K.5
Halldórsson, B.V.6
Hsu, Y.H.7
Zillikens, M.C.8
Wilson, S.G.9
Mullin, B.H.10
Amin, N.11
Aulchenko, Y.S.12
Cupples, L.A.13
Deloukas, P.14
Demissie, S.15
Hofman, A.16
Kong, A.17
Karasik, D.18
Van Meurs, J.B.19
Oostra, B.A.20
Pols, H.A.21
Sigurdsson, G.22
Thorsteinsdottir, U.23
Soranzo, N.24
Williams, F.M.25
Zhou, Y.26
Ralston, S.H.27
Thorleifsson, G.28
Van Duijn, C.M.29
Kiel, D.P.30
Stefansson, K.31
Uitterlinden, A.G.32
Ioannidis, J.P.33
Spector, T.D.34
more..
-
52
-
-
77955364949
-
Molecular genetic studies of gene identification for osteoporosis: The 2009 update
-
Xu XH, Dong SS, Guo Y, Yang TL, Lei SF, Papasian CJ, Zhao M, Deng HW 2010 Molecular genetic studies of gene identification for osteoporosis: the 2009 update. Endocr Rev 31:447-505
-
(2010)
Endocr Rev
, vol.31
, pp. 447-505
-
-
Xu, X.H.1
Dong, S.S.2
Guo, Y.3
Yang, T.L.4
Lei, S.F.5
Papasian, C.J.6
Zhao, M.7
Deng, H.W.8
-
53
-
-
41849149688
-
Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes
-
DOI 10.1359/jbmr.071113
-
Sims AM, Shephard N, Carter K, Doan T, Dowling A, Duncan EL, Eisman J, Jones G, Nicholson G, Prince R, Seeman E, Thomas G, Wass JA, Brown MA 2008 Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes. J Bone Miner Res 23:499-506 (Pubitemid 351501890)
-
(2008)
Journal of Bone and Mineral Research
, vol.23
, Issue.4
, pp. 499-506
-
-
Sims, A.-M.1
Shephard, N.2
Carter, K.3
Doan, T.4
Dowling, A.5
Duncan, E.L.6
Eisman, J.7
Jones, G.8
Nicholson, G.9
Prince, R.10
Seeman, E.11
Thomas, G.12
Wass, J.A.13
Brown, M.A.14
-
54
-
-
67651205715
-
Identifying relationships among genomic disease regions: Predicting genes at pathogenic SNP associations and rare deletions
-
Raychaudhuri S, Plenge RM, Rossin EJ, Ng AC, Purcell SM, Sklar P, Scolnick EM, Xavier RJ, Altshuler D, Daly MJ 2009 Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions. PLoS Genet 5:e1000534
-
(2009)
PLoS Genet
, vol.5
-
-
Raychaudhuri, S.1
Plenge, R.M.2
Rossin, E.J.3
Ng, A.C.4
Purcell, S.M.5
Sklar, P.6
Scolnick, E.M.7
Xavier, R.J.8
Altshuler, D.9
Daly, M.J.10
-
55
-
-
84866668118
-
Assessment of gene-by-sex interaction effect on bone mineral density
-
12 June doi: 10.1002/jbmr.1679
-
Liu CT, Estrada K, Yerges-Armstrong LM, Amin N, Evangelou E, Li G, Minster RL, Carless MA, Kammerer CM, Oei L, Zhou Y, Alonso N, Dailiana Z, Eriksson J, García-Giralt N, Giroux S, Husted LB, Khusainova RI, Koromila T, Kung AW, Lewis JR, Masi L, Mencej-Bedrac S, Nogues X, Patel MS, Prezelj J, Richards JB, Sham PC, Spector T, Vandenput L, Xiao SM, Zheng HF, Zhu K, Balcells S, Brandi ML, Frost M, Goltzman D, et al. 12 June 2012 Assessment of gene-by-sex interaction effect on bone mineral density. J Bone Miner Res doi: 10.1002/jbmr.1679
-
(2012)
J Bone Miner Res
-
-
Liu, C.T.1
Estrada, K.2
Yerges-Armstrong, L.M.3
Amin, N.4
Evangelou, E.5
Li, G.6
Minster, R.L.7
Carless, M.A.8
Kammerer, C.M.9
Oei, L.10
Zhou, Y.11
Alonso, N.12
Dailiana, Z.13
Eriksson, J.14
García-Giralt, N.15
Giroux, S.16
Husted, L.B.17
Khusainova, R.I.18
Koromila, T.19
Kung, A.W.20
Lewis, J.R.21
Masi, L.22
Mencej-Bedrac, S.23
Nogues, X.24
Patel, M.S.25
Prezelj, J.26
Richards, J.B.27
Sham, P.C.28
Spector, T.29
Vandenput, L.30
Xiao, S.M.31
Zheng, H.F.32
Zhu, K.33
Balcells, S.34
Brandi, M.L.35
Frost, M.36
Goltzman, D.37
more..
-
56
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, Rotimi CN, Slatkin M, Valle D, Whittemore AS, Boehnke M, Clark AG, Eichler EE, Gibson G, Haines JL, Mackay TF, McCarroll SA, Visscher PM 2009 Finding the missing heritability of complex diseases. Nature 461:747-753
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
Goldstein, D.B.4
Hindorff, L.A.5
Hunter, D.J.6
McCarthy, M.I.7
Ramos, E.M.8
Cardon, L.R.9
Chakravarti, A.10
Cho, J.H.11
Guttmacher, A.E.12
Kong, A.13
Kruglyak, L.14
Mardis, E.15
Rotimi, C.N.16
Slatkin, M.17
Valle, D.18
Whittemore, A.S.19
Boehnke, M.20
Clark, A.G.21
Eichler, E.E.22
Gibson, G.23
Haines, J.L.24
Mackay, T.F.25
McCarroll, S.A.26
Visscher, P.M.27
more..
-
57
-
-
77957947562
-
Hundreds of variants clustered in genomic loci and biological pathways affect human height
-
Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segrè AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, Mägi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, et al. 2010 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 467:832-838
-
(2010)
Nature
, vol.467
, pp. 832-838
-
-
Lango Allen, H.1
Estrada, K.2
Lettre, G.3
Berndt, S.I.4
Weedon, M.N.5
Rivadeneira, F.6
Willer, C.J.7
Jackson, A.U.8
Vedantam, S.9
Raychaudhuri, S.10
Ferreira, T.11
Wood, A.R.12
Weyant, R.J.13
Segrè, A.V.14
Speliotes, E.K.15
Wheeler, E.16
Soranzo, N.17
Park, J.H.18
Yang, J.19
Gudbjartsson, D.20
Heard-Costa, N.L.21
Randall, J.C.22
Qi, L.23
Vernon Smith, A.24
Mägi, R.25
Pastinen, T.26
Liang, L.27
Heid, I.M.28
Luan, J.29
Thorleifsson, G.30
Winkler, T.W.31
Goddard, M.E.32
Sin Lo, K.33
Palmer, C.34
Workalemahu, T.35
more..
-
58
-
-
78049337953
-
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
-
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Allen HL, Lindgren CM, Luan J, Mägi R, Randall JC, Vedantam S, Winkler TW, Qi L, Workalemahu T, Heid IM, Steinthorsdottir V, Stringham HM, Weedon MN, Wheeler E, Wood AR, Ferreira T, Weyant RJ, Segrè AV, Estrada K, Liang L, Nemesh J, Park JH, Gustafsson S, Kilpeläinen TO, Yang J, Bouatia- Naji N, Esko T, Feitosa MF, Kutalik Z, Mangino M, et al. 2010 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 42:937-948
-
(2010)
Nat Genet
, vol.42
, pp. 937-948
-
-
Speliotes, E.K.1
Willer, C.J.2
Berndt, S.I.3
Monda, K.L.4
Thorleifsson, G.5
Jackson, A.U.6
Allen, H.L.7
Lindgren, C.M.8
Luan, J.9
Mägi, R.10
Randall, J.C.11
Vedantam, S.12
Winkler, T.W.13
Qi, L.14
Workalemahu, T.15
Heid, I.M.16
Steinthorsdottir, V.17
Stringham, H.M.18
Weedon, M.N.19
Wheeler, E.20
Wood, A.R.21
Ferreira, T.22
Weyant, R.J.23
Segrè, A.V.24
Estrada, K.25
Liang, L.26
Nemesh, J.27
Park, J.H.28
Gustafsson, S.29
Kilpeläinen, T.O.30
Yang, J.31
Bouatia-Naji, N.32
Esko, T.33
Feitosa, M.F.34
Kutalik, Z.35
Mangino, M.36
more..
-
59
-
-
79952195585
-
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
-
Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, Baldassano RN, Barclay M, Bayless TM, Brand S, Büning C, Colombel JF, Denson LA, De Vos M, Dubinsky M, Edwards C, Ellinghaus D, Fehrmann RS, Floyd JA, Florin T, Franchimont D, Franke L, Georges M, Glas J, Glazer NL, Guthery SL, Haritunians T, Hayward NK, et al. 2011 Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet 43:246-252
-
(2011)
Nat Genet
, vol.43
, pp. 246-252
-
-
Anderson, C.A.1
Boucher, G.2
Lees, C.W.3
Franke, A.4
D'Amato, M.5
Taylor, K.D.6
Lee, J.C.7
Goyette, P.8
Imielinski, M.9
Latiano, A.10
Lagacé, C.11
Scott, R.12
Amininejad, L.13
Bumpstead, S.14
Baidoo, L.15
Baldassano, R.N.16
Barclay, M.17
Bayless, T.M.18
Brand, S.19
Büning, C.20
Colombel, J.F.21
Denson, L.A.22
De Vos, M.23
Dubinsky, M.24
Edwards, C.25
Ellinghaus, D.26
Fehrmann, R.S.27
Floyd, J.A.28
Florin, T.29
Franchimont, D.30
Franke, L.31
Georges, M.32
Glas, J.33
Glazer, N.L.34
Guthery, S.L.35
Haritunians, T.36
Hayward, N.K.37
more..
-
60
-
-
79251480074
-
Genetic profiling and individualized prognosis of fracture
-
Tran BN, Nguyen ND, Nguyen VX, Center JR, Eisman JA, Nguyen TV 2011 Genetic profiling and individualized prognosis of fracture. J Bone Miner Res 26:414-419
-
(2011)
J Bone Miner Res
, vol.26
, pp. 414-419
-
-
Tran, B.N.1
Nguyen, N.D.2
Nguyen, V.X.3
Center, J.R.4
Eisman, J.A.5
Nguyen, T.V.6
-
61
-
-
33751329250
-
Global variation in copy number in the human genome
-
DOI 10.1038/nature05329, PII NATURE05329
-
Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S, Freeman JL, González JR, Gratacòs M, Huang J, Kalaitzopoulos D, Komura D, MacDonald JR, Marshall CR, Mei R, Montgomery L, Nishimura K, Okamura K, Shen F, Somerville MJ, Tchinda J, Valsesia A, Woodwark C, Yang F, Zhang J, Zerjal T, Zhang J, Armengol L, Conrad DF, Estivill X, Tyler-Smith C, Carter NP, Aburatani H, Lee C, Jones KW, Scherer SW, Hurles ME 2006 Global variation in copy number in the human genome. Nature 444:444-454 (Pubitemid 44809057)
-
(2006)
Nature
, vol.444
, Issue.7118
, pp. 444-454
-
-
Redon, R.1
Ishikawa, S.2
Fitch, K.R.3
Feuk, L.4
Perry, G.H.5
Andrews, T.D.6
Fiegler, H.7
Shapero, M.H.8
Carson, A.R.9
Chen, W.10
Cho, E.K.11
Dallaire, S.12
Freeman, J.L.13
Gonzalez, J.R.14
Gratacos, M.15
Huang, J.16
Kalaitzopoulos, D.17
Komura, D.18
MacDonald, J.R.19
Marshall, C.R.20
Mei, R.21
Montgomery, L.22
Nishimura, K.23
Okamura, K.24
Shen, F.25
Somerville, M.J.26
Tchinda, J.27
Valsesia, A.28
Woodwark, C.29
Yang, F.30
Zhang, J.31
Zerjal, T.32
Zhang, J.33
Armengol, L.34
Conrad, D.F.35
Estivill, X.36
Tyler-Smith, C.37
Carter, N.P.38
Aburatani, H.39
Lee, C.40
Jones, K.W.41
Scherer, S.W.42
Hurles, M.E.43
more..
-
62
-
-
33846978695
-
Relative impact of nucleotide and copy number variation on gene expression phenotypes
-
Stranger BE, Forrest MS, Dunning M, Ingle CE, Beazley C, Thorne N, Redon R, Bird CP, de Grassi A, Lee C, Tyler-Smith C, Carter N, Scherer SW, Tavaré S, Deloukas P, Hurles ME, Dermitzakis ET 2007 Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science 315:848-853
-
(2007)
Science
, vol.315
, pp. 848-853
-
-
Stranger, B.E.1
Forrest, M.S.2
Dunning, M.3
Ingle, C.E.4
Beazley, C.5
Thorne, N.6
Redon, R.7
Bird, C.P.8
De Grassi, A.9
Lee, C.10
Tyler-Smith, C.11
Carter, N.12
Scherer, S.W.13
Tavaré, S.14
Deloukas, P.15
Hurles, M.E.16
Dermitzakis, E.T.17
-
63
-
-
55949100282
-
Small-scale copy number variation and large-scale changes in gene expression
-
Mileyko Y, Joh RI, Weitz JS 2008 Small-scale copy number variation and large-scale changes in gene expression. Proc Natl Acad Sci USA 105:16659-16664
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 16659-16664
-
-
Mileyko, Y.1
Joh, R.I.2
Weitz, J.S.3
-
64
-
-
57149123783
-
Genomewide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis
-
Yang TL, Chen XD, Guo Y, Lei SF, Wang JT, Zhou Q, Pan F, Chen Y, Zhang ZX, Dong SS, Xu XH, Yan H, Liu X, Qiu C, Zhu XZ, Chen T, Li M, Zhang H, Zhang L, Drees BM, Hamilton JJ, Papasian CJ, Recker RR, Song XP, Cheng J, Deng HW 2008 Genomewide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis. Am J Hum Genet 83:663-674
-
(2008)
Am J Hum Genet
, vol.83
, pp. 663-674
-
-
Yang, T.L.1
Chen, X.D.2
Guo, Y.3
Lei, S.F.4
Wang, J.T.5
Zhou, Q.6
Pan, F.7
Chen, Y.8
Zhang, Z.X.9
Dong, S.S.10
Xu, X.H.11
Yan, H.12
Liu, X.13
Qiu, C.14
Zhu, X.Z.15
Chen, T.16
Li, M.17
Zhang, H.18
Zhang, L.19
Drees, B.M.20
Hamilton, J.J.21
Papasian, C.J.22
Recker, R.R.23
Song, X.P.24
Cheng, J.25
Deng, H.W.26
more..
-
65
-
-
77950961444
-
Genome-wide copy number variation association study suggested VPS13B gene for osteoporosis in Caucasians
-
Deng FY, Zhao LJ, Pei YF, Sha BY, Liu XG, Yan H, Wang L, Yang TL, Recker RR, Papasian CJ, Deng HW 2010 Genome-wide copy number variation association study suggested VPS13B gene for osteoporosis in Caucasians. Osteoporos Int 21:579-587
-
(2010)
Osteoporos Int
, vol.21
, pp. 579-587
-
-
Deng, F.Y.1
Zhao, L.J.2
Pei, Y.F.3
Sha, B.Y.4
Liu, X.G.5
Yan, H.6
Wang, L.7
Yang, T.L.8
Recker, R.R.9
Papasian, C.J.10
Deng, H.W.11
-
66
-
-
79960307586
-
Copy number variation in CNP267 region may be associated with hip bone size
-
Liu SL, Lei SF, Yang F, Li X, Liu R, Nie S, Liu XG, Yang TL, Guo Y, Deng FY, Tian Q, Li J, Liu YZ, Liu YJ, Shen H, Deng HW 2011 Copy number variation in CNP267 region may be associated with hip bone size. PLoS One 6:e22035
-
(2011)
PLoS One
, vol.6
-
-
Liu, S.L.1
Lei, S.F.2
Yang, F.3
Li, X.4
Liu, R.5
Nie, S.6
Liu, X.G.7
Yang, T.L.8
Guo, Y.9
Deng, F.Y.10
Tian, Q.11
Li, J.12
Liu, Y.Z.13
Liu, Y.J.14
Shen, H.15
Deng, H.W.16
-
67
-
-
85027951876
-
Homozygous deletion of the UGT2B17 gene is not associated with osteoporosis risk in elderly Caucasian women
-
Chew S, Mullin BH, Lewis JR, Spector TD, Prince RL, Wilson SG 2011 Homozygous deletion of the UGT2B17 gene is not associated with osteoporosis risk in elderly Caucasian women. Osteoporos Int 22:1981-1986
-
(2011)
Osteoporos Int
, vol.22
, pp. 1981-1986
-
-
Chew, S.1
Mullin, B.H.2
Lewis, J.R.3
Spector, T.D.4
Prince, R.L.5
Wilson, S.G.6
-
68
-
-
79957588287
-
Genome partitioning of genetic variation for complex traits using common SNPs
-
Yang J, Manolio TA, Pasquale LR, Boerwinkle E, Caporaso N, Cunningham JM, de Andrade M, Feenstra B, Feingold E, Hayes MG, Hill WG, Landi MT, Alonso A, Lettre G, Lin P, Ling H, Lowe W, Mathias RA, Melbye M, Pugh E, Cornelis MC, Weir BS, Goddard ME, Visscher PM 2011 Genome partitioning of genetic variation for complex traits using common SNPs. Nat Genet 43:519-525
-
(2011)
Nat Genet
, vol.43
, pp. 519-525
-
-
Yang, J.1
Manolio, T.A.2
Pasquale, L.R.3
Boerwinkle, E.4
Caporaso, N.5
Cunningham, J.M.6
De Andrade, M.7
Feenstra, B.8
Feingold, E.9
Hayes, M.G.10
Hill, W.G.11
Landi, M.T.12
Alonso, A.13
Lettre, G.14
Lin, P.15
Ling, H.16
Lowe, W.17
Mathias, R.A.18
Melbye, M.19
Pugh, E.20
Cornelis, M.C.21
Weir, B.S.22
Goddard, M.E.23
Visscher, P.M.24
more..
-
69
-
-
70349303959
-
Bayesian statistical methods for genetic association studies
-
Stephens M, Balding DJ 2009 Bayesian statistical methods for genetic association studies. Nat Rev Genet 10:681-690
-
(2009)
Nat Rev Genet
, vol.10
, pp. 681-690
-
-
Stephens, M.1
Balding, D.J.2
-
70
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
2007 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447:661-678
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
71
-
-
84860333083
-
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis
-
Stahl EA, Wegmann D, Trynka G, Gutierrez-Achury J, Do R, Voight BF, Kraft P, Chen R, Kallberg HJ, Kurreeman FA, Kathiresan S, Wijmenga C, Gregersen PK, Alfredsson L, Siminovitch KA, Worthington J, de Bakker PI, Raychaudhuri S, Plenge RM 2012 Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis. Nat Genet 44:483-489
-
(2012)
Nat Genet
, vol.44
, pp. 483-489
-
-
Stahl, E.A.1
Wegmann, D.2
Trynka, G.3
Gutierrez-Achury, J.4
Do, R.5
Voight, B.F.6
Kraft, P.7
Chen, R.8
Kallberg, H.J.9
Kurreeman, F.A.10
Kathiresan, S.11
Wijmenga, C.12
Gregersen, P.K.13
Alfredsson, L.14
Siminovitch, K.A.15
Worthington, J.16
De Bakker, P.I.17
Raychaudhuri, S.18
Plenge, R.M.19
-
72
-
-
34547782270
-
A bayesian measure of the probability of false discovery in genetic epidemiology studies
-
DOI 10.1086/519024
-
Wakefield J 2007 A Bayesian measure of the probability of false discovery in genetic epidemiology studies. Am J Hum Genet 81: 208-227 (Pubitemid 47236070)
-
(2007)
American Journal of Human Genetics
, vol.81
, Issue.2
, pp. 208-227
-
-
Wakefield, J.1
-
73
-
-
74049157110
-
Meta-analysis of genetic association studies: Methodologies, between-study heterogeneity and winner's curse
-
Nakaoka H, Inoue I 2009 Meta-analysis of genetic association studies: methodologies, between-study heterogeneity and winner's curse. J Hum Genet 54:615-623
-
(2009)
J Hum Genet
, vol.54
, pp. 615-623
-
-
Nakaoka, H.1
Inoue, I.2
-
74
-
-
41049093347
-
The combination of estimates from different experiments
-
Cochran WG 1954 The combination of estimates from different experiments. Biometrics 10:101-129
-
(1954)
Biometrics
, vol.10
, pp. 101-129
-
-
Cochran, W.G.1
-
75
-
-
0037098199
-
Quantifying heterogeneity in a meta-analysis
-
DOI 10.1002/sim.1186
-
Higgins JP, Thompson SG 2002 Quantifying heterogeneity in a meta-analysis. Stat Med 21:1539-1558 (Pubitemid 34746062)
-
(2002)
Statistics in Medicine
, vol.21
, Issue.11
, pp. 1539-1558
-
-
Higgins, J.P.T.1
Thompson, S.G.2
-
76
-
-
28444493739
-
Combining probability from independent tests: The weighted Z-method is superior to Fisher's approach
-
DOI 10.1111/j.1420-9101.2005.00917.x
-
Whitlock MC 2005 Combining probability from independent tests: the weighted Z-method is superior to Fisher's approach. J Evol Biol 18:1368-1373 (Pubitemid 41725687)
-
(2005)
Journal of Evolutionary Biology
, vol.18
, Issue.5
, pp. 1368-1373
-
-
Whitlock, M.C.1
-
77
-
-
0022992740
-
Meta-analysis in clinical trials
-
DOI 10.1016/0197-2456(86)90046-2
-
DerSimonian R, Laird N 1986 Meta-analysis in clinical trials. Control Clin Trials 7:177-188 (Pubitemid 17189972)
-
(1986)
Controlled Clinical Trials
, vol.7
, Issue.3
, pp. 177-188
-
-
DerSimonian, R.1
Laird, N.2
-
78
-
-
78049323331
-
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants
-
Li Y, Vinckenbosch N, Tian G, Huerta-Sanchez E, Jiang T, Jiang H, Albrechtsen A, Andersen G, Cao H, Korneliussen T, Grarup N, Guo Y, Hellman I, Jin X, Li Q, Liu J, Liu X, Sparsø T, Tang M, Wu H, Wu R, Yu C, Zheng H, Astrup A, Bolund L, Holmkvist J, Jørgensen T, Kristiansen K, Schmitz O, Schwartz TW, Zhang X, Li R, Yang H, Wang J, Hansen T, Pedersen O, Nielsen R, Wang J 2010 Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants. Nat Genet 42:969-972
-
(2010)
Nat Genet
, vol.42
, pp. 969-972
-
-
Li, Y.1
Vinckenbosch, N.2
Tian, G.3
Huerta-Sanchez, E.4
Jiang, T.5
Jiang, H.6
Albrechtsen, A.7
Andersen, G.8
Cao, H.9
Korneliussen, T.10
Grarup, N.11
Guo, Y.12
Hellman, I.13
Jin, X.14
Li, Q.15
Liu, J.16
Liu, X.17
Sparsø, T.18
Tang, M.19
Wu, H.20
Wu, R.21
Yu, C.22
Zheng, H.23
Astrup, A.24
Bolund, L.25
Holmkvist, J.26
Jørgensen, T.27
Kristiansen, K.28
Schmitz, O.29
Schwartz, T.W.30
Zhang, X.31
Li, R.32
Yang, H.33
Wang, J.34
Hansen, T.35
Pedersen, O.36
Nielsen, R.37
Wang, J.38
more..
-
79
-
-
38749145596
-
Shifting Paradigm of Association Studies: Value of Rare Single-Nucleotide Polymorphisms
-
DOI 10.1016/j.ajhg.2007.09.006, PII S0002929707000122
-
Gorlov IP, Gorlova OY, Sunyaev SR, Spitz MR, Amos CI 2008 Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms. Am J Hum Genet 82:100-112 (Pubitemid 351726083)
-
(2008)
American Journal of Human Genetics
, vol.82
, Issue.1
, pp. 100-112
-
-
Gorlov, I.P.1
Gorlova, O.Y.2
Sunyaev, S.R.3
Spitz, M.R.4
Amos, C.I.5
-
80
-
-
77249134594
-
Rare variants create synthetic genome-wide associations
-
Dickson SP, Wang K, Krantz I, Hakonarson H, Goldstein DB 2010 Rare variants create synthetic genome-wide associations. PLoS Biol 8:e1000294
-
(2010)
PLoS Biol
, vol.8
-
-
Dickson, S.P.1
Wang, K.2
Krantz, I.3
Hakonarson, H.4
Goldstein, D.B.5
-
81
-
-
79851487366
-
The importance of synthetic associations will only be resolved empirically
-
Goldstein DB 2011 The importance of synthetic associations will only be resolved empirically. PLoS Biol 9:e1001008
-
(2011)
PLoS Biol
, vol.9
-
-
Goldstein, D.B.1
-
82
-
-
79851468862
-
Synthetic associations are unlikely to account for many common disease genome-wide association signals
-
Anderson CA, Soranzo N, Zeggini E, Barrett JC 2011 Synthetic associations are unlikely to account for many common disease genome-wide association signals. PLoS Biol 9:e1000580
-
(2011)
PLoS Biol
, vol.9
-
-
Anderson, C.A.1
Soranzo, N.2
Zeggini, E.3
Barrett, J.C.4
-
83
-
-
62649084535
-
Power of deep, all-exon resequencing for discovery of human trait genes
-
Kryukov GV, Shpunt A, Stamatoyannopoulos JA, Sunyaev SR 2009 Power of deep, all-exon resequencing for discovery of human trait genes. Proc Natl Acad Sci USA 106:3871-3876
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3871-3876
-
-
Kryukov, G.V.1
Shpunt, A.2
Stamatoyannopoulos, J.A.3
Sunyaev, S.R.4
-
84
-
-
3843056691
-
Multiple rare alleles contribute to low plasma levels of HDL cholesterol
-
DOI 10.1126/science.1099870
-
Cohen JC, Kiss RS, Pertsemlidis A, Marcel YL, McPherson R, Hobbs HH 2004 Multiple rare alleles contribute to low plasma levels of HDL cholesterol. Science 305:869-872 (Pubitemid 39038422)
-
(2004)
Science
, vol.305
, Issue.5685
, pp. 869-872
-
-
Cohen, J.C.1
Kiss, R.S.2
Pertsemlidis, A.3
Marcel, Y.L.4
McPherson, R.5
Hobbs, H.H.6
-
85
-
-
65249131713
-
Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes
-
Nejentsev S, Walker N, Riches D, Egholm M, Todd JA 2009 Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes. Science 324:387-389
-
(2009)
Science
, vol.324
, pp. 387-389
-
-
Nejentsev, S.1
Walker, N.2
Riches, D.3
Egholm, M.4
Todd, J.A.5
-
86
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
DOI 10.1126/science.1145720
-
Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, Shen D, Boca SM, Barber T, Ptak J, Silliman N, Szabo S, Dezso Z, Ustyanksky V, Nikolskaya T, Nikolsky Y, Karchin R, Wilson PA, Kaminker JS, Zhang Z, Croshaw R, Willis J, Dawson D, Shipitsin M, Willson JK, Sukumar S, Polyak K, Park BH, Pethiyagoda CL, Pant PV, Ballinger DG, Sparks AB, Hartigan J, Smith DR, Suh E, Papadopoulos N, Buckhaults P, Markowitz SD, Parmigiani G, Kinzler KW, Velculescu VE, Vogelstein B 2007 The genomic landscapes of human breast and colorectal cancers. Science 318:1108-1113 (Pubitemid 350134889)
-
(2007)
Science
, vol.318
, Issue.5853
, pp. 1108-1113
-
-
Wood, L.D.1
Parsons, D.W.2
Jones, S.3
Lin, J.4
Sjoblom, T.5
Leary, R.J.6
Shen, D.7
Boca, S.M.8
Barber, T.9
Ptak, J.10
Silliman, N.11
Szabo, S.12
Dezso, Z.13
Ustyanksky, V.14
Nikolskaya, T.15
Nikolsky, Y.16
Karchin, R.17
Wilson, P.A.18
Kaminker, J.S.19
Zhang, Z.20
Croshaw, R.21
Willis, J.22
Dawson, D.23
Shipitsin, M.24
Willson, J.K.V.25
Sukumar, S.26
Polyak, K.27
Ben, H.P.28
Pethiyagoda, C.L.29
Pant, P.V.K.30
Ballinger, D.G.31
Sparks, A.B.32
Hartigan, J.33
Smith, D.R.34
Suh, E.35
Papadopoulos, N.36
Buckhaults, P.37
Markowitz, S.D.38
Parmigiani, G.39
Kinzler, K.W.40
Velculescu, V.E.41
Vogelstein, B.42
more..
-
87
-
-
34047177395
-
Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL
-
DOI 10.1038/ng1984, PII NG1984
-
Romeo S, Pennacchio LA, Fu Y, Boerwinkle E, Tybjaerg-Hansen A, Hobbs HH, Cohen JC 2007 Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL. Nat Genet 39:513-516 (Pubitemid 46514768)
-
(2007)
Nature Genetics
, vol.39
, Issue.4
, pp. 513-516
-
-
Romeo, S.1
Pennacchio, L.A.2
Fu, Y.3
Boerwinkle, E.4
Tybjaerg-Hansen, A.5
Hobbs, H.H.6
Cohen, J.C.7
-
88
-
-
77952096810
-
Rare deletions at 16p13.11 predispose to a diverse spectrum of sporadic epilepsy syndromes
-
Heinzen EL, Radtke RA, Urban TJ, Cavalleri GL, Depondt C, Need AC, Walley NM, Nicoletti P, Ge D, Catarino CB, Duncan JS, KasperaviciÛte D, Tate SK, Caboclo LO, Sander JW, Clayton L, Linney KN, Shianna KV, Gumbs CE, Smith J, Cronin KD, Maia JM, Doherty CP, Pandolfo M, Leppert D, Middleton LT, Gibson RA, Johnson MR, Matthews PM, Hosford D, Kälviäinen R, Eriksson K, Kantanen AM, Dorn T, Hansen J, Krämer G, Steinhoff BJ, Wieser HG, Zumsteg D, Ortega M, Wood NW, Huxley-Jones J, Mikati M, Gallentine WB, Husain AM, Buckley PG, Stallings RL, Podgoreanu MV, Delanty N, Sisodiya SM, Goldstein DB 2010 Rare deletions at 16p13.11 predispose to a diverse spectrum of sporadic epilepsy syndromes. Am J Hum Genet 86:707-718
-
(2010)
Am J Hum Genet
, vol.86
, pp. 707-718
-
-
Heinzen, E.L.1
Radtke, R.A.2
Urban, T.J.3
Cavalleri, G.L.4
Depondt, C.5
Need, A.C.6
Walley, N.M.7
Nicoletti, P.8
Ge, D.9
Catarino, C.B.10
Duncan, J.S.11
KasperaviciÛte, D.12
Tate, S.K.13
Caboclo, L.O.14
Sander, J.W.15
Clayton, L.16
Linney, K.N.17
Shianna, K.V.18
Gumbs, C.E.19
Smith, J.20
Cronin, K.D.21
Maia, J.M.22
Doherty, C.P.23
Pandolfo, M.24
Leppert, D.25
Middleton, L.T.26
Gibson, R.A.27
Johnson, M.R.28
Matthews, P.M.29
Hosford, D.30
Kälviäinen, R.31
Eriksson, K.32
Kantanen, A.M.33
Dorn, T.34
Hansen, J.35
Krämer, G.36
Steinhoff, B.J.37
Wieser, H.G.38
Zumsteg, D.39
Ortega, M.40
Wood, N.W.41
Huxley-Jones, J.42
Mikati, M.43
Gallentine, W.B.44
Husain, A.M.45
Buckley, P.G.46
Stallings, R.L.47
Podgoreanu, M.V.48
Delanty, N.49
Sisodiya, S.M.50
Goldstein, D.B.51
more..
-
89
-
-
42649084334
-
Rare independent mutations in renal salt handling genes contribute to blood pressure variation
-
Ji W, Foo JN, O'Roak BJ, Zhao H, Larson MG, Simon DB, Newton- Cheh C, State MW, Levy D, Lifton RP 2008 Rare independent mutations in renal salt handling genes contribute to blood pressure variation. Nat Genet 40:592-599
-
(2008)
Nat Genet
, vol.40
, pp. 592-599
-
-
Ji, W.1
Foo, J.N.2
O'Roak, B.J.3
Zhao, H.4
Larson, M.G.5
Simon, D.B.6
Newton-Cheh, C.7
State, M.W.8
Levy, D.9
Lifton, R.P.10
-
90
-
-
79957589237
-
Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations
-
O'Roak BJ, Deriziotis P, Lee C, Vives L, Schwartz JJ, Girirajan S, Karakoc E, Mackenzie AP, Ng SB, Baker C, Rieder MJ, Nickerson DA, Bernier R, Fisher SE, Shendure J, Eichler EE 2011 Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations. Nat Genet 43:585-589
-
(2011)
Nat Genet
, vol.43
, pp. 585-589
-
-
O'Roak, B.J.1
Deriziotis, P.2
Lee, C.3
Vives, L.4
Schwartz, J.J.5
Girirajan, S.6
Karakoc, E.7
Mackenzie, A.P.8
Ng, S.B.9
Baker, C.10
Rieder, M.J.11
Nickerson, D.A.12
Bernier, R.13
Fisher, S.E.14
Shendure, J.15
Eichler, E.E.16
-
91
-
-
76649136928
-
An evaluation of statistical approaches to rare variant analysis in genetic association studies
-
Morris AP, Zeggini E 2010 An evaluation of statistical approaches to rare variant analysis in genetic association studies. Genet Epidemiol 34:188-193
-
(2010)
Genet Epidemiol
, vol.34
, pp. 188-193
-
-
Morris, A.P.1
Zeggini, E.2
-
92
-
-
77951974619
-
Interpretation of association signals and identification of causal variants from genome-wide association studies
-
Wang K, Dickson SP, Stolle CA, Krantz ID, Goldstein DB, Hakonarson H 2010 Interpretation of association signals and identification of causal variants from genome-wide association studies. Am J Hum Genet 86:730-742
-
(2010)
Am J Hum Genet
, vol.86
, pp. 730-742
-
-
Wang, K.1
Dickson, S.P.2
Stolle, C.A.3
Krantz, I.D.4
Goldstein, D.B.5
Hakonarson, H.6
-
93
-
-
79960700796
-
Next generation genome-wide association tool: Design and coverage of a high-throughput European-optimized SNP array
-
Hoffmann TJ, Kvale MN, Hesselson SE, Zhan Y, Aquino C, Cao Y, Cawley S, Chung E, Connell S, Eshragh J, Ewing M, Gollub J, Henderson M, Hubbell E, Iribarren C, Kaufman J, Lao RZ, Lu Y, Ludwig D, Mathauda GK, McGuire W, Mei G, Miles S, Purdy MM, Quesenberry C, Ranatunga D, Rowell S, Sadler M, Shapero MH, Shen L, Shenoy TR, Smethurst D, Van den Eeden SK, Walter L, Wan E, Wearley R, Webster T, Wen CC, Weng L, Whitmer RA, Williams A, Wong SC, Zau C, Finn A, Schaefer C, Kwok PY, Risch N 2011 Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array. Genomics 98:79-89
-
(2011)
Genomics
, vol.98
, pp. 79-89
-
-
Hoffmann, T.J.1
Kvale, M.N.2
Hesselson, S.E.3
Zhan, Y.4
Aquino, C.5
Cao, Y.6
Cawley, S.7
Chung, E.8
Connell, S.9
Eshragh, J.10
Ewing, M.11
Gollub, J.12
Henderson, M.13
Hubbell, E.14
Iribarren, C.15
Kaufman, J.16
Lao, R.Z.17
Lu, Y.18
Ludwig, D.19
Mathauda, G.K.20
McGuire, W.21
Mei, G.22
Miles, S.23
Purdy, M.M.24
Quesenberry, C.25
Ranatunga, D.26
Rowell, S.27
Sadler, M.28
Shapero, M.H.29
Shen, L.30
Shenoy, T.R.31
Smethurst, D.32
Van Den Eeden, S.K.33
Walter, L.34
Wan, E.35
Wearley, R.36
Webster, T.37
Wen, C.C.38
Weng, L.39
Whitmer, R.A.40
Williams, A.41
Wong, S.C.42
Zau, C.43
Finn, A.44
Schaefer, C.45
Kwok, P.Y.46
Risch, N.47
more..
-
94
-
-
84856405512
-
The mystery of missing heritability: Genetic interactions create phantom heritability
-
Zuk O, Hechter E, Sunyaev SR, Lander ES 2012 The mystery of missing heritability: genetic interactions create phantom heritability. Proc Natl Acad Sci USA 109:1193-1198
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 1193-1198
-
-
Zuk, O.1
Hechter, E.2
Sunyaev, S.R.3
Lander, E.S.4
-
95
-
-
16844366786
-
Genome-wide strategies for detecting multiple loci that influence complex diseases
-
Marchini J, Donnelly P, Cardon LR 2005 Genome-wide strategies for detecting multiple loci that influence complex diseases. Nat Genet 37:413-417
-
(2005)
Nat Genet
, vol.37
, pp. 413-417
-
-
Marchini, J.1
Donnelly, P.2
Cardon, L.R.3
-
96
-
-
56549099067
-
Sex-specific genetic architecture of human disease
-
DOI 10.1038/nrg2415, PII NRG2415
-
Ober C, Loisel DA, Gilad Y 2008 Sex-specific genetic architecture of human disease. Nat Rev Genet 9:911-922 (Pubitemid 50329067)
-
(2008)
Nature Reviews Genetics
, vol.9
, Issue.12
, pp. 911-922
-
-
Ober, C.1
Loisel, D.A.2
Gilad, Y.3
-
97
-
-
49549091386
-
Contribution of gender-specific genetic factors to osteoporosis risk
-
Karasik D, Ferrari SL 2008 Contribution of gender-specific genetic factors to osteoporosis risk. Ann Hum Genet 72:696-714
-
(2008)
Ann Hum Genet
, vol.72
, pp. 696-714
-
-
Karasik, D.1
Ferrari, S.L.2
-
98
-
-
34547146985
-
Network medicine - From obesity to the "diseasome"
-
Barabási AL 2007 Network medicine - from obesity to the "diseasome". N Engl J Med 357:404-407
-
(2007)
N Engl J Med
, vol.357
, pp. 404-407
-
-
Barabási, A.L.1
-
99
-
-
0038670579
-
Thehumanphenome project
-
Freimer N, Sabatti C 2003 Thehumanphenome project. Nat Genet 34:15-21
-
(2003)
Nat Genet
, vol.34
, pp. 15-21
-
-
Freimer, N.1
Sabatti, C.2
-
100
-
-
34547140875
-
The human disease network
-
DOI 10.1073/pnas.0701361104
-
Goh KI, Cusick ME, Valle D, Childs B, Vidal M, Barabási AL 2007 The human disease network. Proc Natl Acad Sci USA 104:8685-8690 (Pubitemid 47175372)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.21
, pp. 8685-8690
-
-
Goh, K.-I.1
Cusick, M.E.2
Valle, D.3
Childs, B.4
Vidal, M.5
Barabasi, A.-L.6
-
101
-
-
77954717620
-
Genome-wide pleiotropy of osteoporosis-related phenotypes: The Framingham Study
-
Karasik D, Hsu YH, Zhou Y, Cupples LA, Kiel DP, Demissie S 2010 Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study. J Bone Miner Res 25:1555-1563
-
(2010)
J Bone Miner Res
, vol.25
, pp. 1555-1563
-
-
Karasik, D.1
Hsu, Y.H.2
Zhou, Y.3
Cupples, L.A.4
Kiel, D.P.5
Demissie, S.6
-
102
-
-
68149183602
-
Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density
-
Thorleifsson G, Holm H, Edvardsson V, Walters GB, Styrkarsdottir U, Gudbjartsson DF, Sulem P, Halldorsson BV, de Vegt F, d'Ancona FC, den Heijer M, Franzson L, Christiansen C, Alexandersen P, Rafnar T, Kristjansson K, Sigurdsson G, Kiemeney LA, Bodvarsson M, Indridason OS, Palsson R, Kong A, Thorsteinsdottir U, Stefansson K 2009 Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density. Nat Genet 41:926-930
-
(2009)
Nat Genet
, vol.41
, pp. 926-930
-
-
Thorleifsson, G.1
Holm, H.2
Edvardsson, V.3
Walters, G.B.4
Styrkarsdottir, U.5
Gudbjartsson, D.F.6
Sulem, P.7
Halldorsson, B.V.8
De Vegt, F.9
D'Ancona, F.C.10
Den Heijer, M.11
Franzson, L.12
Christiansen, C.13
Alexandersen, P.14
Rafnar, T.15
Kristjansson, K.16
Sigurdsson, G.17
Kiemeney, L.A.18
Bodvarsson, M.19
Indridason, O.S.20
Palsson, R.21
Kong, A.22
Thorsteinsdottir, U.23
Stefansson, K.24
more..
-
103
-
-
84864387123
-
Leveraging genomewide association data to detect genetic pleiotropy at loci associated with glycemic and skeletal phenotypes
-
the MAGIC Investigators, the DIAGRAM Consortium, the MuTHER Consortium
-
Billings L, Hsu YH, Ackerman R, Dupuis J, Voight B, Rasmussen- Torvik LJ, Hercberg S, Lathrop M, Barnes D, Langenberg C, Hui J, Fu M, Bouatia-Naji N, Lecoeur C, An P, Magnusson PK, Surakka I, Ripatti S, Christiansen L, Dalgård C, Folkersen L, Grundberg E, the MAGIC Investigators, the DIAGRAM Consortium, the MuTHER Consortium, et al. 2012 Leveraging genomewide association data to detect genetic pleiotropy at loci associated with glycemic and skeletal phenotypes. Diabetes 61:2176-2186
-
(2012)
Diabetes
, vol.61
, pp. 2176-2186
-
-
Billings, L.1
Hsu, Y.H.2
Ackerman, R.3
Dupuis, J.4
Voight, B.5
Rasmussen-Torvik, L.J.6
Hercberg, S.7
Lathrop, M.8
Barnes, D.9
Langenberg, C.10
Hui, J.11
Fu, M.12
Bouatia-Naji, N.13
Lecoeur, C.14
An, P.15
Magnusson, P.K.16
Surakka, I.17
Ripatti, S.18
Christiansen, L.19
Dalgård, C.20
Folkersen, L.21
Grundberg, E.22
more..
-
104
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T, Lees CW, Balschun T, Lee J, Roberts R, Anderson CA, Bis JC, Bumpstead S, Ellinghaus D, Festen EM, Georges M, Green T, Haritunians T, Jostins L, Latiano A, Mathew CG, Montgomery GW, Prescott NJ, Raychaudhuri S, Rotter JI, Schumm P, Sharma Y, Simms LA, Taylor KD, Whiteman D, Wijmenga C, Baldassano RN, Barclay M, Bayless TM, Brand S, et al. 2010 Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet 42:1118-1125
-
(2010)
Nat Genet
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
Wang, K.4
Radford-Smith, G.L.5
Ahmad, T.6
Lees, C.W.7
Balschun, T.8
Lee, J.9
Roberts, R.10
Anderson, C.A.11
Bis, J.C.12
Bumpstead, S.13
Ellinghaus, D.14
Festen, E.M.15
Georges, M.16
Green, T.17
Haritunians, T.18
Jostins, L.19
Latiano, A.20
Mathew, C.G.21
Montgomery, G.W.22
Prescott, N.J.23
Raychaudhuri, S.24
Rotter, J.I.25
Schumm, P.26
Sharma, Y.27
Simms, L.A.28
Taylor, K.D.29
Whiteman, D.30
Wijmenga, C.31
Baldassano, R.N.32
Barclay, M.33
Bayless, T.M.34
Brand, S.35
more..
-
105
-
-
61349163553
-
Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1
-
Zheng W, Long J, Gao YT, Li C, Zheng Y, Xiang YB, Wen W, Levy S, Deming SL, Haines JL, Gu K, Fair AM, Cai Q, Lu W, Shu XO 2009 Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1. Nat Genet 41:324-328
-
(2009)
Nat Genet
, vol.41
, pp. 324-328
-
-
Zheng, W.1
Long, J.2
Gao, Y.T.3
Li, C.4
Zheng, Y.5
Xiang, Y.B.6
Wen, W.7
Levy, S.8
Deming, S.L.9
Haines, J.L.10
Gu, K.11
Fair, A.M.12
Cai, Q.13
Lu, W.14
Shu, X.O.15
-
106
-
-
84867247641
-
-
The Joint Statistical Meetings/American Statistics Association, Miami Beach, FL, Abstract #300323
-
Hsu YH, Chen X, A multivariate approach on genome-wide association studies (GWAS) by modeling multiple traits simultaneously to identify pleiotropic genetic effects (invited papers). The Joint Statistical Meetings/American Statistics Association, Miami Beach, FL, 2011 (Abstract #300323)
-
(2011)
A Multivariate Approach on Genome-wide Association Studies (GWAS) by Modeling Multiple Traits Simultaneously to Identify Pleiotropic Genetic Effects (Invited Papers).
-
-
Hsu, Y.H.1
Chen, X.2
-
107
-
-
84867261736
-
Genome-widebivariate association analysis identifies novel candidate genes for ages at menarche and natural menopause and for bone mineral density: The ReproGen and GEFOS Consortia
-
Abstract OR17-4
-
Hsu YH, Chen X, Elks C, Murabito J, Estrada K, Harris TB, Lunetta KL, Murray A, Ong KK, Perry JR, Rivadeneira FR, Stolk L, Uitterlinden AG, Zillikens CM, Kiel DP, Karasik D, Genome-widebivariate association analysis identifies novel candidate genes for ages at menarche and natural menopause and for bone mineral density: the ReproGen and GEFOS Consortia. Program of the 93rd Annual
-
(2011)
Program of the 93rd Annual Meeting of the Endocrine Society, Boston, MA
-
-
Hsu, Y.H.1
Chen, X.2
Elks, C.3
Murabito, J.4
Estrada, K.5
Harris, T.B.6
Lunetta, K.L.7
Murray, A.8
Ong, K.K.9
Perry, J.R.10
Rivadeneira, F.R.11
Stolk, L.12
Uitterlinden, A.G.13
Zillikens, C.M.14
Kiel, D.P.15
Karasik, D.16
-
108
-
-
84867247646
-
Multi-phenotype genome-wide association meta-analysis on both lean body mass and BMD identified novel pleiotropic genes that affected skeletal muscle and bone metabolism in European descent Caucasian populations
-
Hsu YH, Chen X, Zillikens C, Estrada K, Demissie S, Liu C, Zhou Y, Karasik D, Murabito J, Uitterlinden A, Cupples L, Rivadeneira F, Kiel D 2011 Multi-phenotype genome-wide association meta-analysis on both lean body mass and BMD identified novel pleiotropic genes that affected skeletal muscle and bone metabolism in European descent Caucasian populations. J Bone Miner Res 26:(Suppl 1):S56
-
(2011)
J Bone Miner Res
, vol.26
, Issue.SUPPL. 1
-
-
Hsu, Y.H.1
Chen, X.2
Zillikens, C.3
Estrada, K.4
Demissie, S.5
Liu, C.6
Zhou, Y.7
Karasik, D.8
Murabito, J.9
Uitterlinden, A.10
Cupples, L.11
Rivadeneira, F.12
Kiel, D.13
-
109
-
-
84867265981
-
Meta-analysis of genome-wide association study (GWAS) identifies several genes for hip bone geometry in Caucasians: The Genetic Factors for Osteoporosis (GEFOS) Consortium
-
Hsu Y, Beck TJ, Brown SJ, Cauley JA, Demissie S, Estrada K, Glazer N, Kaptoge SK, Kiel DP, Richards B, Rivadeneira F, Robbins JA, Soranzo N, Spector TD, Streeten EA, Uitterlinden AG, Wilson SG, Yerges-Armstrong LM, Zillikens C, Karasik D 2010 Meta-analysis of genome-wide association study (GWAS) identifies several genes for hip bone geometry in Caucasians: the Genetic Factors for Osteoporosis (GEFOS) Consortium. J Bone Miner Res 25(Suppl 1):S448
-
(2010)
J Bone Miner Res
, vol.25
, Issue.SUPPL. 1
-
-
Hsu, Y.1
Beck, T.J.2
Brown, S.J.3
Cauley, J.A.4
Demissie, S.5
Estrada, K.6
Glazer, N.7
Kaptoge, S.K.8
Kiel, D.P.9
Richards, B.10
Rivadeneira, F.11
Robbins, J.A.12
Soranzo, N.13
Spector, T.D.14
Streeten, E.A.15
Uitterlinden, A.G.16
Wilson, S.G.17
Yerges-Armstrong, L.M.18
Zillikens, C.19
Karasik, D.20
more..
-
110
-
-
84867252524
-
Meta-analysis of genomewide association study identifies three loci influencing serum osteoprotegerin levels
-
Cheung CL, Hsu YH, Eriksson J, Kwan J, Karasik D, Benjamin E, Fontes J, Kiel DP, Lorentzon M, Larson M, Kung A, Chee KW, Ohlsson C, Sham PC, Dupuis J 2011 Meta-analysis of genomewide association study identifies three loci influencing serum osteoprotegerin levels. J Bone Miner Res 26(Suppl 1):S442
-
(2011)
J Bone Miner Res
, vol.26
, Issue.SUPPL. 1
-
-
Cheung, C.L.1
Hsu, Y.H.2
Eriksson, J.3
Kwan, J.4
Karasik, D.5
Benjamin, E.6
Fontes, J.7
Kiel, D.P.8
Lorentzon, M.9
Larson, M.10
Kung, A.11
Chee, K.W.12
Ohlsson, C.13
Sham, P.C.14
Dupuis, J.15
-
111
-
-
84867257478
-
Genome-wide association study of hip fracture suggests loci in biological pathways associated with bone remodeling
-
Jackson R, LaCroix A, Aragaki A, Duggan D, Carlson C, Richards B, Dastani Z, Spector T, Eisman J, Nguyen T, Ralston S, McCloskey E, Duncan E, Nicholson G, Leslie W, Goltzman D, Krishnan S, Kooperberg C 2011 Genome-wide association study of hip fracture suggests loci in biological pathways associated with bone remodeling. J Bone Miner Res 26(Suppl 1):S346
-
(2011)
J Bone Miner Res
, vol.26
, Issue.SUPPL. 1
-
-
Jackson, R.1
LaCroix, A.2
Aragaki, A.3
Duggan, D.4
Carlson, C.5
Richards, B.6
Dastani, Z.7
Spector, T.8
Eisman, J.9
Nguyen, T.10
Ralston, S.11
McCloskey, E.12
Duncan, E.13
Nicholson, G.14
Leslie, W.15
Goltzman, D.16
Krishnan, S.17
Kooperberg, C.18
-
112
-
-
84867261734
-
Large-scale meta-analysis of genome-wide association studies for fracture risk: The GEFOS Consortium
-
Abstract 847W
-
Oei L, Zheng HF, Ntzani E, Estrada K, Ridker P, Garcia ME, Hsu YH, Lehtimäki T, Trompet S, Kaptoge SK, Wilson S, Liu Y, Eriksson J, Amin N, Kung A, Gomez CM, Tsilidis K, Rose K, Vernon-Smith A, Liu CT, Viikari J, Moayyeri A, Minster R, Lorentzon M, Xiao SM, Wareham NJ, Aalto V, Aspelund T, Cummings S, Cupples LA, Evangelou E, Khaw KT, Luben RN, Raitakari O, Siggeirsdottir K, van Duijn CM, Cauley J, Karasik D, Sham PC, Zillikens C, Ohlsson C, Harris TB, Spector TD, Reeve J, Jukema W, Ioannidis J, Kahonen M, Kiel DP, Gudnason V, Uitterlinden AG, Chasman DI, Richards B, Rivadeneira F, Large-scale meta-analysis of genome-wide association studies for fracture risk: The GEFOS Consortium. Proc 61st Annual Meeting of the American Society of Human Genetics, Montreal, Canada, 2011 (Abstract 847W)
-
Proc 61st Annual Meeting of the American Society of Human Genetics, Montreal, Canada, 2011
-
-
Oei, L.1
Zheng, H.F.2
Ntzani, E.3
Estrada, K.4
Ridker, P.5
Garcia, M.E.6
Hsu, Y.H.7
Lehtimäki, T.8
Trompet, S.9
Kaptoge, S.K.10
Wilson, S.11
Liu, Y.12
Eriksson, J.13
Amin, N.14
Kung, A.15
Gomez, C.M.16
Tsilidis, K.17
Rose, K.18
Vernon-Smith, A.19
Liu, C.T.20
Viikari, J.21
Moayyeri, A.22
Minster, R.23
Lorentzon, M.24
Xiao, S.M.25
Wareham, N.J.26
Aalto, V.27
Aspelund, T.28
Cummings, S.29
Cupples, L.A.30
Evangelou, E.31
Khaw, K.T.32
Luben, R.N.33
Raitakari, O.34
Siggeirsdottir, K.35
Van Duijn, C.M.36
Cauley, J.37
Karasik, D.38
Sham, P.C.39
Zillikens, C.40
Ohlsson, C.41
Harris, T.B.42
Spector, T.D.43
Reeve, J.44
Jukema, W.45
Ioannidis, J.46
Kahonen, M.47
Kiel, D.P.48
Gudnason, V.49
Uitterlinden, A.G.50
Chasman, D.I.51
Richards, B.52
Rivadeneira, F.53
more..
-
113
-
-
43049175471
-
FRAX and the assessment of fracture probability in men and women from the UK
-
Kanis JA, Johnell O, Oden A, Johansson H, McCloskey E 2008 FRAX and the assessment of fracture probability in men and women from the UK. Osteoporos Int 19:385-397
-
(2008)
Osteoporos Int
, vol.19
, pp. 385-397
-
-
Kanis, J.A.1
Johnell, O.2
Oden, A.3
Johansson, H.4
McCloskey, E.5
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