An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility loci for osteoporosis-related traits

PLoS Genetics

Volumn 6, Issue 6, 2010, Pages 1-16

  Hsu, Yi Hsiang ^a,b,c   Zillikens, M Carola ^d,e   Wilson, Scott G ^f,g,h   Farber, Charles R ⁱ   Demissie, Serkalem ^c,j   Soranzo, Nicole ^f,k   Bianchi, Estelle N ^l   Grundberg, Elin ^k,m   Liang, Liming ^b   Richards, J Brent ^f,m,n   Estrada, Karol ^d,e   Zhou, Yanhua ^c,j   van Nas, Atila ^o   Moffatt, Miriam F ^p   Zhai, Guangju ^f   Hofman, Albert ^d,e   van Meurs, Joyce B ^d,e   Pols, Huibert A P ^d   Price, Roger I ^g   Nilsson, Olle ^q   Pastinen, Tomi ^m   Cupples, L Adrienne ^c,j   Lusis, Aldons J ^o   Schadt, Eric E ^r   Ferrari, Serge ^l   Uitterlinden, André G ^d,e   Rivadeneira, Fernando ^d,e   Spector, Timothy D ^f   Karasik, David ^a,c   Kiel, Douglas P ^a,c   more..

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c FRAMINGHAM HEART STUDY   (United States)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e Netherlands Genomics Initiative   (Netherlands)

^f KING'S COLLEGE LONDON   (United Kingdom)

^g SIR CHARLES GAIRDNER HOSPITAL   (Australia)

^h UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

ⁱ UNIVERSITY OF VIRGINIA   (United States)

^j BOSTON UNIVERSITY   (United States)

^k WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^l GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^m MCGILL UNIVERSITY   (Canada)

ⁿ MCGILL UNIVERSITY   (Canada)

^o UNIVERSITY OF CALIFORNIA   (United States)

^p NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^q UPPSALA UNIVERSITY   (Sweden)

^r ROSETTA INPHARMATICS   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; OSTEOPROTEGERIN; PROTEIN OSBPL1A; PROTEIN RAP1A; PROTEIN TBC1D8; UNCLASSIFIED DRUG;

ARTICLE; BONE DENSITY; CAUCASIAN; CHROMOSOME 1P; DISEASE MODEL; FEMUR NECK; GENE EXPRESSION PROFILING; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC TRAIT; HUMAN; LUMBAR SPINE; LYMPHOCYTE; NONHUMAN; OSTEOBLAST; OSTEOPOROSIS; PHENOTYPE; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; ANIMAL; C57BL MOUSE; CELL CULTURE; FEMALE; GENETIC PREDISPOSITION; GENETIC TRANSCRIPTION; GENETICS; MALE; MOUSE; PATHOPHYSIOLOGY;

ANIMALIA;

ANIMALS; BONE DENSITY; CELLS, CULTURED; FEMALE; GENE EXPRESSION PROFILING; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MICE; MICE, INBRED C57BL; OSTEOPOROSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; TRANSCRIPTION, GENETIC;

EID: 77954157408     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000977     Document Type: Article

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