Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-β

Journal of Biological Chemistry

Volumn 287, Issue 41, 2012, Pages 34134-34148

  Jana, Malabendu ^a   Mondal, Susanta ^a   Gonzalez, Frank J ^b   Pahan, Kalipada ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-INFLAMMATORIES; ANTISENSE; CELL RECEPTORS; CHROMATIN IMMUNOPRECIPITATION ANALYSIS; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GEMFIBROZILS; GLIAL CELLS; GLYCOPROTEIN GENES; IN-VIVO; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEIN; OLIGODENDROCYTES; ORGANOTYPIC CULTURE; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PHOSPHODIESTERASES; REMYELINATION; SPINAL CORDS; STIMULATORY EFFECTS; THERAPEUTIC USE; TRANSGENIC MICE; WILD TYPES;

CELL CULTURE; CELL MEMBRANES; GENE EXPRESSION; GLYCOPROTEINS; MAMMALS;

DRUG PRODUCTS;

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; ANTILIPEMIC AGENT; GEMFIBROZIL; MYELIN BASIC PROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEOLIPID PROTEIN; T LYMPHOCYTE RECEPTOR;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CELL ISOLATION; CHROMATIN IMMUNOPRECIPITATION; CNPASE GENE; CONTROLLED STUDY; DRUG MECHANISM; FETUS; GENE; GENE EXPRESSION; GLIA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MBP GENE; MOG GENE; MOUSE; NONHUMAN; OLIGODENDROGLIA; PLP GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SPINAL CORD;

ANIMALS; CELLS, CULTURED; DEMYELINATING DISEASES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GEMFIBROZIL; GENE EXPRESSION REGULATION; HUMANS; HYPOLIPIDEMIC AGENTS; MICE; MICE, KNOCKOUT; MYELIN SHEATH; NERVE TISSUE PROTEINS; OLIGODENDROGLIA; PPAR GAMMA; PPAR-BETA; RESPONSE ELEMENTS;

EID: 84867260723     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.398552     Document Type: Article

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