-
1
-
-
77951640946
-
A method and server for predicting damaging missense mutations
-
Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, Kondrashov AS, Sunyaev SR. 2010. A method and server for predicting damaging missense mutations. Nat Methods 7: 248-249.
-
(2010)
Nat Methods
, vol.7
, pp. 248-249
-
-
Adzhubei, I.A.1
Schmidt, S.2
Peshkin, L.3
Ramensky, V.E.4
Gerasimova, A.5
Bork, P.6
Kondrashov, A.S.7
Sunyaev, S.R.8
-
2
-
-
77953280591
-
Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor
-
Andersen RJ, Mawji NR, Wang J, Wang G, Haile S, Myung JK, Watt K, Tam T, Yang YC, Banuelos CA, Williams DE, McEwan IJ, Wang Y, Sadar MD. 2010. Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor. Cancer Cell 17: 535-546.
-
(2010)
Cancer Cell
, vol.17
, pp. 535-546
-
-
Andersen, R.J.1
Mawji, N.R.2
Wang, J.3
Wang, G.4
Haile, S.5
Myung, J.K.6
Watt, K.7
Tam, T.8
Yang, Y.C.9
Banuelos, C.A.10
Williams, D.E.11
McEwan, I.J.12
Wang, Y.13
Sadar, M.D.14
-
3
-
-
48249150750
-
Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer
-
Attard G, Clark J, Ambroisine L, Mills IG, Fisher G, Flohr P, Reid A, Edwards S, Kovacs G, Berney D, Foster C, Massie CE, Fletcher A, De Bono JS, Scardino P, Cuzick J, Cooper CS. 2008. Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer. Br J Cancer 99: 314-320.
-
(2008)
Br J Cancer
, vol.99
, pp. 314-320
-
-
Attard, G.1
Clark, J.2
Ambroisine, L.3
Mills, I.G.4
Fisher, G.5
Flohr, P.6
Reid, A.7
Edwards, S.8
Kovacs, G.9
Berney, D.10
Foster, C.11
Massie, C.E.12
Fletcher, A.13
De Bono, J.S.14
Scardino, P.15
Cuzick, J.16
Cooper, C.S.17
-
4
-
-
79951497419
-
The genomic complexity of primary human prostate cancer
-
Berger MF, Lawrence MS, Demichelis F, Drier Y, Cibulskis K, Sivachenko AY, Sboner A, Esgueva R, Pflueger D, Sougnez C, Onofrio R, Carter SL, Park K, Habegger L, Ambrogio L, Fennell T, Parkin M, Saksena G, Voet D, Ramos AH, Pugh TJ, Wilkinson J, Fisher S, Winckler W, Mahan S, Ardlie K, Baldwin J, Simons JW, Kitabayashi N, MacDonald TY, Kantoff PW, Chin L, Gabriel SB, Gerstein MB, Golub TR, Meyerson M, Tewari A, Lander ES, Getz G, Rubin MA, Garraway LA. 2011. The genomic complexity of primary human prostate cancer. Nature 470: 214-220.
-
(2011)
Nature
, vol.470
, pp. 214-220
-
-
Berger, M.F.1
Lawrence, M.S.2
Demichelis, F.3
Drier, Y.4
Cibulskis, K.5
Sivachenko, A.Y.6
Sboner, A.7
Esgueva, R.8
Pflueger, D.9
Sougnez, C.10
Onofrio, R.11
Carter, S.L.12
Park, K.13
Habegger, L.14
Ambrogio, L.15
Fennell, T.16
Parkin, M.17
Saksena, G.18
Voet, D.19
Ramos, A.H.20
Pugh, T.J.21
Wilkinson, J.22
Fisher, S.23
Winckler, W.24
Mahan, S.25
Ardlie, K.26
Baldwin, J.27
Simons, J.W.28
Kitabayashi, N.29
MacDonald, T.Y.30
Kantoff, P.W.31
Chin, L.32
Gabriel, S.B.33
Gerstein, M.B.34
Golub, T.R.35
Meyerson, M.36
Tewari, A.37
Lander, E.S.38
Getz, G.39
Rubin, M.A.40
Garraway, L.A.41
more..
-
5
-
-
79955968629
-
Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer
-
Brenner JC, Ateeq B, Li Y, Yocum AK, Cao Q, Asangani IA, Patel S, Wang X, Liang H, Yu J, Palanisamy N, Siddiqui J, Yan W, Cao X, Mehra R, Sabolch A, Basrur V, Lonigro RJ, Yang J, Tomlins SA, Maher CA, Elenitoba-Johnson KS, Hussain M, Navone NM, Pienta KJ, Varambally S, Feng FY, Chinnaiyan AM. 2011. Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer. Cancer Cell 19: 664-678.
-
(2011)
Cancer Cell
, vol.19
, pp. 664-678
-
-
Brenner, J.C.1
Ateeq, B.2
Li, Y.3
Yocum, A.K.4
Cao, Q.5
Asangani, I.A.6
Patel, S.7
Wang, X.8
Liang, H.9
Yu, J.10
Palanisamy, N.11
Siddiqui, J.12
Yan, W.13
Cao, X.14
Mehra, R.15
Sabolch, A.16
Basrur, V.17
Lonigro, R.J.18
Yang, J.19
Tomlins, S.A.20
Maher, C.A.21
Elenitoba-Johnson, K.S.22
Hussain, M.23
Navone, N.M.24
Pienta, K.J.25
Varambally, S.26
Feng, F.Y.27
Chinnaiyan, A.M.28
more..
-
6
-
-
79958837494
-
Structural effects of the L145Q, V157F, and R282W cancer-associated mutations in the p53 DNA-binding core domain
-
Calhoun S, Daggett V. 2011. Structural effects of the L145Q, V157F, and R282W cancer-associated mutations in the p53 DNA-binding core domain. Biochemistry 50: 5345-5353.
-
(2011)
Biochemistry
, vol.50
, pp. 5345-5353
-
-
Calhoun, S.1
Daggett, V.2
-
7
-
-
70350109641
-
ETS gene fusions in prostate cancer
-
Clark JP, Cooper CS. 2009. ETS gene fusions in prostate cancer. Nat Rev Urol 6: 429-439.
-
(2009)
Nat Rev Urol
, vol.6
, pp. 429-439
-
-
Clark, J.P.1
Cooper, C.S.2
-
8
-
-
79953715693
-
Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, Condel
-
Gonzalez-Perez A, Lopez-Bigas N. 2011. Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, Condel. Am J Hum Genet 88: 440-449.
-
(2011)
Am J Hum Genet
, vol.88
, pp. 440-449
-
-
Gonzalez-Perez, A.1
Lopez-Bigas, N.2
-
9
-
-
0037816165
-
Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis
-
Kato S, Han SY, Liu W, Otsuka K, Shibata H, Kanamaru R, Ishioka C. 2003. Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis. Proc Natl Acad Sci USA 100: 8424-8429.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8424-8429
-
-
Kato, S.1
Han, S.Y.2
Liu, W.3
Otsuka, K.4
Shibata, H.5
Kanamaru, R.6
Ishioka, C.7
-
10
-
-
79955416773
-
Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline
-
Kloosterman WP, Guryev V, van Roosmalen M, Duran KJ, de Bruijn E, Bakker SC, Letteboer T, van Nesselrooij B, Hochstenbach R, Poot M, Cuppen E. 2011a. Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline. Hum Mol Genet 20: 1916-1924.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 1916-1924
-
-
Kloosterman, W.P.1
Guryev, V.2
van Roosmalen, M.3
Duran, K.J.4
de Bruijn, E.5
Bakker, S.C.6
Letteboer, T.7
van Nesselrooij, B.8
Hochstenbach, R.9
Poot, M.10
Cuppen, E.11
-
11
-
-
80054698731
-
Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer
-
Kloosterman WP, Hoogstraat M, Paling O, Tavakoli-Yaraki M, Renkens I, Vermaat JS, van Roosmalen MJ, van Lieshout S, Nijman IJ, Roessingh W, van 't Slot R, van de Belt J, Guryev V, Koudijs M, Voest E, Cuppen E. 2011b. Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer. Genome Biol 12: R103.
-
(2011)
Genome Biol
, vol.12
-
-
Kloosterman, W.P.1
Hoogstraat, M.2
Paling, O.3
Tavakoli-Yaraki, M.4
Renkens, I.5
Vermaat, J.S.6
van Roosmalen, M.J.7
van Lieshout, S.8
Nijman, I.J.9
Roessingh, W.10
van 't Slot, R.11
van de Belt, J.12
Guryev, V.13
Koudijs, M.14
Voest, E.15
Cuppen, E.16
-
12
-
-
69649109364
-
Circos: An information aesthetic for comparative genomics
-
Krzywinski M, Schein J, Birol I, Connors J, Gascoyne R, Horsman D, Jones SJ, Marra MA. 2009. Circos: An information aesthetic for comparative genomics. Genome Res 19: 1639-1645.
-
(2009)
Genome Res
, vol.19
, pp. 1639-1645
-
-
Krzywinski, M.1
Schein, J.2
Birol, I.3
Connors, J.4
Gascoyne, R.5
Horsman, D.6
Jones, S.J.7
Marra, M.A.8
-
13
-
-
80054751998
-
Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers
-
Kumar A, White TA, MacKenzie AP, Clegg N, Lee C, Dumpit RF, Coleman I, Ng SB, Salipante SJ, Rieder MJ, Nickerson DA, Corey E, Lange PH, Morrissey C, Vessella RL, Nelson PS, Shendure J. 2011. Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers. Proc Natl Acad Sci USA 108: 17087-17092.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 17087-17092
-
-
Kumar, A.1
White, T.A.2
MacKenzie, A.P.3
Clegg, N.4
Lee, C.5
Dumpit, R.F.6
Coleman, I.7
Ng, S.B.8
Salipante, S.J.9
Rieder, M.J.10
Nickerson, D.A.11
Corey, E.12
Lange, P.H.13
Morrissey, C.14
Vessella, R.L.15
Nelson, P.S.16
Shendure, J.17
-
14
-
-
84975685847
-
From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer
-
Lapuk AV, Wu C, Wyatt AW, McPherson A, McConeghy BJ, Brahmbhatt S, Mo F, Zoubeidi A, Anderson S, Bell RH, Haegert A, Shukin R, Wang Y, Fazli L, Hurtado-Coll A, Jones EC, Hach F, Hormozdiari F, Hajiresouliha I, Boutros PC, Bristow RG, Zhao Y, Marra MA, Fanjul A, Maher CA, Chinnaiyan AM, Rubin MA, Beltran H, Sahinalp SC, Gleave ME, Volik SV, Collins CC. 2012. From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer. J Pathol 227: 286-297.
-
(2012)
J Pathol
, vol.227
, pp. 286-297
-
-
Lapuk, A.V.1
Wu, C.2
Wyatt, A.W.3
McPherson, A.4
McConeghy, B.J.5
Brahmbhatt, S.6
Mo, F.7
Zoubeidi, A.8
Anderson, S.9
Bell, R.H.10
Haegert, A.11
Shukin, R.12
Wang, Y.13
Fazli, L.14
Hurtado-Coll, A.15
Jones, E.C.16
Hach, F.17
Hormozdiari, F.18
Hajiresouliha, I.19
Boutros, P.C.20
Bristow, R.G.21
Zhao, Y.22
Marra, M.A.23
Fanjul, A.24
Maher, C.A.25
Chinnaiyan, A.M.26
Rubin, M.A.27
Beltran, H.28
Sahinalp, S.C.29
Gleave, M.E.30
Volik, S.V.31
Collins, C.C.32
more..
-
15
-
-
77949587649
-
Fast and accurate long-read alignment with Burrows-Wheeler transform
-
Li H, Durbin R. 2010. Fast and accurate long-read alignment with Burrows-Wheeler transform. Bioinformatics 26: 589-595.
-
(2010)
Bioinformatics
, vol.26
, pp. 589-595
-
-
Li, H.1
Durbin, R.2
-
16
-
-
68549104404
-
The sequence alignment/map format and SAMtools
-
Li H, Handsaker B, Wysoker A, Fennell T, Ruan J, Homer N, Marth G, Abecasis G, Durbin R. 2009. The sequence alignment/map format and SAMtools. Bioinformatics 25: 2078-2079.
-
(2009)
Bioinformatics
, vol.25
, pp. 2078-2079
-
-
Li, H.1
Handsaker, B.2
Wysoker, A.3
Fennell, T.4
Ruan, J.5
Homer, N.6
Marth, G.7
Abecasis, G.8
Durbin, R.9
-
17
-
-
80052916562
-
Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements
-
Liu P, Erez A, Nagamani SC, Dhar SU, Kolodziejska KE, Dharmadhikari AV, Cooper ML, Wiszniewska J, Zhang F, Withers MA, Bacino CA, Campos-Acevedo LD, Delgado MR, Freedenberg D, Garnica A, Grebe TA, Hernandez-Almaguer D, Immken L, Lalani SR, McLean SD, Northrup H, Scaglia F, Strathearn L, Trapane P, Kang SH, Patel A, Cheung SW, Hastings PJ, Stankiewicz P, Lupski JR, Bi W. 2011. Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements. Cell 146: 889-903.
-
(2011)
Cell
, vol.146
, pp. 889-903
-
-
Liu, P.1
Erez, A.2
Nagamani, S.C.3
Dhar, S.U.4
Kolodziejska, K.E.5
Dharmadhikari, A.V.6
Cooper, M.L.7
Wiszniewska, J.8
Zhang, F.9
Withers, M.A.10
Bacino, C.A.11
Campos-Acevedo, L.D.12
Delgado, M.R.13
Freedenberg, D.14
Garnica, A.15
Grebe, T.A.16
Hernandez-Almaguer, D.17
Immken, L.18
Lalani, S.R.19
McLean, S.D.20
Northrup, H.21
Scaglia, F.22
Strathearn, L.23
Trapane, P.24
Kang, S.H.25
Patel, A.26
Cheung, S.W.27
Hastings, P.J.28
Stankiewicz, P.29
Lupski, J.R.30
Bi, W.31
more..
-
18
-
-
79960693423
-
Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients
-
Magrangeas F, Avet-Loiseau H, Munshi NC, Minvielle S. 2011. Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients. Blood 118: 675-678.
-
(2011)
Blood
, vol.118
, pp. 675-678
-
-
Magrangeas, F.1
Avet-Loiseau, H.2
Munshi, N.C.3
Minvielle, S.4
-
19
-
-
62049085786
-
Transcriptome sequencing to detect gene fusions in cancer
-
Maher CA, Kumar-Sinha C, Cao X, Kalyana-Sundaram S, Han B, Jing X, Sam L, Barrette T, Palanisamy N, Chinnaiyan AM. 2009a. Transcriptome sequencing to detect gene fusions in cancer. Nature 458: 97-101.
-
(2009)
Nature
, vol.458
, pp. 97-101
-
-
Maher, C.A.1
Kumar-Sinha, C.2
Cao, X.3
Kalyana-Sundaram, S.4
Han, B.5
Jing, X.6
Sam, L.7
Barrette, T.8
Palanisamy, N.9
Chinnaiyan, A.M.10
-
20
-
-
68149176840
-
Chimeric transcript discovery by paired-end transcriptome sequencing
-
Maher CA, Palanisamy N, Brenner JC, Cao X, Kalyana-Sundaram S, Luo S, Khrebtukova I, Barrette TR, Grasso C, Yu J, Lonigro RJ, Schroth G, Kumar-Sinha C, Chinnaiyan AM. 2009b. Chimeric transcript discovery by paired-end transcriptome sequencing. Proc Natl Acad Sci USA 106: 12353-12358.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 12353-12358
-
-
Maher, C.A.1
Palanisamy, N.2
Brenner, J.C.3
Cao, X.4
Kalyana-Sundaram, S.5
Luo, S.6
Khrebtukova, I.7
Barrette, T.R.8
Grasso, C.9
Yu, J.10
Lonigro, R.J.11
Schroth, G.12
Kumar-Sinha, C.13
Chinnaiyan, A.M.14
-
21
-
-
84863393824
-
Chromothripsis and human disease: Piecing together the shattering process
-
Maher CA, Wilson RK. 2012. Chromothripsis and human disease: Piecing together the shattering process. Cell 148: 29-32.
-
(2012)
Cell
, vol.148
, pp. 29-32
-
-
Maher, C.A.1
Wilson, R.K.2
-
22
-
-
84863261471
-
Chromosome rearrangement associated inactivation of tumour suppressor genes in prostate cancer
-
Mao X, Boyd LK, Yanez-Munoz RJ, Chaplin T, Xue L, Lin D, Shan L, Berney DM, Young BD, Lu YJ. 2011. Chromosome rearrangement associated inactivation of tumour suppressor genes in prostate cancer. Am J Cancer Res 1: 604-617.
-
(2011)
Am J Cancer Res
, vol.1
, pp. 604-617
-
-
Mao, X.1
Boyd, L.K.2
Yanez-Munoz, R.J.3
Chaplin, T.4
Xue, L.5
Lin, D.6
Shan, L.7
Berney, D.M.8
Young, B.D.9
Lu, Y.J.10
-
23
-
-
79957829805
-
deFuse: An algorithm for gene fusion discovery in tumor RNA-Seq data
-
McPherson A, Hormozdiari F, Zayed A, Giuliany R, Ha G, Sun MG, Griffith M, Heravi Moussavi A, Senz J, Melnyk N, Pacheco M, Marra MA, Hirst M, Nielsen TO, Sahinalp SC, Huntsman D, Shah SP. 2011a. deFuse: An algorithm for gene fusion discovery in tumor RNA-Seq data. PLoS Comput Biol 7: e1001138.
-
(2011)
PLoS Comput Biol
, vol.7
-
-
McPherson, A.1
Hormozdiari, F.2
Zayed, A.3
Giuliany, R.4
Ha, G.5
Sun, M.G.6
Griffith, M.7
Heravi Moussavi, A.8
Senz, J.9
Melnyk, N.10
Pacheco, M.11
Marra, M.A.12
Hirst, M.13
Nielsen, T.O.14
Sahinalp, S.C.15
Huntsman, D.16
Shah, S.P.17
-
24
-
-
79957875348
-
Comrad: A novel algorithmic framework for the integrated analysis of RNA-Seq and WGSS data
-
McPherson A, Wu C, Hajirasouliha I, Hormozdiari F, Hach F, Lapuk A, Volik S, Shah S, Collins C, Sahinalp SC. 2011b. Comrad: A novel algorithmic framework for the integrated analysis of RNA-Seq and WGSS data. Bioinformatics 27: 1481-1488.
-
(2011)
Bioinformatics
, vol.27
, pp. 1481-1488
-
-
McPherson, A.1
Wu, C.2
Hajirasouliha, I.3
Hormozdiari, F.4
Hach, F.5
Lapuk, A.6
Volik, S.7
Shah, S.8
Collins, C.9
Sahinalp, S.C.10
-
25
-
-
84868332770
-
nFuse: Discovery of complex genomic rearrangements in cancer using high-throughput sequencing
-
2012.
-
McPherson A, Wu C, Wyatt AW, Shah S, Collins C, Sahinalp SC. nFuse: Discovery of complex genomic rearrangements in cancer using high-throughput sequencing. Genome Res 2012.
-
Genome Res
-
-
McPherson, A.1
Wu, C.2
Wyatt, A.W.3
Shah, S.4
Collins, C.5
Sahinalp, S.C.6
-
26
-
-
0035026704
-
Predicting deleterious amino acid substitutions
-
Ng PC, Henikoff S. 2001. Predicting deleterious amino acid substitutions. Genome Res 11: 863-874.
-
(2001)
Genome Res
, vol.11
, pp. 863-874
-
-
Ng, P.C.1
Henikoff, S.2
-
27
-
-
34248379012
-
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database
-
Petitjean A, Mathe E, Kato S, Ishioka C, Tavtigian SV, Hainaut P, Olivier M. 2007. Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database. Hum Mutat 28: 622-629.
-
(2007)
Hum Mutat
, vol.28
, pp. 622-629
-
-
Petitjean, A.1
Mathe, E.2
Kato, S.3
Ishioka, C.4
Tavtigian, S.V.5
Hainaut, P.6
Olivier, M.7
-
28
-
-
78651476339
-
Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing
-
Pflueger D, Terry S, Sboner A, Habegger L, Esgueva R, Lin PC, Svensson MA, Kitabayashi N, Moss BJ, MacDonald TY, Cao X, Barrette T, Tewari AK, Chee MS, Chinnaiyan AM, Rickman DS, Demichelis F, Gerstein MB, Rubin MA. 2011. Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing. Genome Res 21: 56-67.
-
(2011)
Genome Res
, vol.21
, pp. 56-67
-
-
Pflueger, D.1
Terry, S.2
Sboner, A.3
Habegger, L.4
Esgueva, R.5
Lin, P.C.6
Svensson, M.A.7
Kitabayashi, N.8
Moss, B.J.9
MacDonald, T.Y.10
Cao, X.11
Barrette, T.12
Tewari, A.K.13
Chee, M.S.14
Chinnaiyan, A.M.15
Rickman, D.S.16
Demichelis, F.17
Gerstein, M.B.18
Rubin, M.A.19
-
29
-
-
48249117488
-
Multiple tumors in a child with germ-line mutations in TP53 and PTEN
-
Plon SE, Pirics ML, Nuchtern J, Hicks J, Russell H, Agrawal S, Zbuk K, Eng C, Hegde M, Chin EL. 2008. Multiple tumors in a child with germ-line mutations in TP53 and PTEN. N Engl J Med 359: 537-539.
-
(2008)
N Engl J Med
, vol.359
, pp. 537-539
-
-
Plon, S.E.1
Pirics, M.L.2
Nuchtern, J.3
Hicks, J.4
Russell, H.5
Agrawal, S.6
Zbuk, K.7
Eng, C.8
Hegde, M.9
Chin, E.L.10
-
30
-
-
77953957633
-
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
-
Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, Pandolfi PP. 2010. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 465: 1033-1038.
-
(2010)
Nature
, vol.465
, pp. 1033-1038
-
-
Poliseno, L.1
Salmena, L.2
Zhang, J.3
Carver, B.4
Haveman, W.J.5
Pandolfi, P.P.6
-
31
-
-
35848942129
-
Fbw7 and Usp28 regulate myc protein stability in response to DNA damage
-
Popov N, Herold S, Llamazares M, Schulein C, Eilers M. 2007. Fbw7 and Usp28 regulate myc protein stability in response to DNA damage. Cell Cycle 6: 2327-2331.
-
(2007)
Cell Cycle
, vol.6
, pp. 2327-2331
-
-
Popov, N.1
Herold, S.2
Llamazares, M.3
Schulein, C.4
Eilers, M.5
-
32
-
-
82155186923
-
The emergence of lncRNAs in cancer biology
-
Prensner JR, Chinnaiyan AM. 2011. The emergence of lncRNAs in cancer biology. Cancer Discov 1: 391-407.
-
(2011)
Cancer Discov
, vol.1
, pp. 391-407
-
-
Prensner, J.R.1
Chinnaiyan, A.M.2
-
33
-
-
78651321775
-
Structure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1
-
Rappas M, Oliver AW, Pearl LH. 2011. Structure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1. Nucleic Acids Res 39: 313-324.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 313-324
-
-
Rappas, M.1
Oliver, A.W.2
Pearl, L.H.3
-
34
-
-
84862907577
-
Genome sequencing of Pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
-
Rausch T, Jones DT, Zapatka M, Stutz AM, Zichner T, Weischenfeldt J, Jager N, Remke M, Shih D, Northcott PA, Pfaff E, Tica J, Wang Q, Massimi L, Witt H, Bender S, Pleier S, Cin H, Hawkins C, Beck C, von Deimling A, Hans V, Brors B, Eils R, Scheurlen W, Blake J, Benes V, Kulozik AE, Witt O, Martin D, Zhang C, Porat R, Merino DM, Wasserman J, Jabado N, Fontebasso A, Bullinger L, Rucker FG, Dohner K, Dohner H, Koster J, Molenaar JJ, Versteeg R, Kool M, Tabori U, Malkin D, Korshunov A, Taylor MD, Lichter P, Pfister SM, Korbel JO. 2012. Genome sequencing of Pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell 148: 59-71.
-
(2012)
Cell
, vol.148
, pp. 59-71
-
-
Rausch, T.1
Jones, D.T.2
Zapatka, M.3
Stutz, A.M.4
Zichner, T.5
Weischenfeldt, J.6
Jager, N.7
Remke, M.8
Shih, D.9
Northcott, P.A.10
Pfaff, E.11
Tica, J.12
Wang, Q.13
Massimi, L.14
Witt, H.15
Bender, S.16
Pleier, S.17
Cin, H.18
Hawkins, C.19
Beck, C.20
von Deimling, A.21
Hans, V.22
Brors, B.23
Eils, R.24
Scheurlen, W.25
Blake, J.26
Benes, V.27
Kulozik, A.E.28
Witt, O.29
Martin, D.30
Zhang, C.31
Porat, R.32
Merino, D.M.33
Wasserman, J.34
Jabado, N.35
Fontebasso, A.36
Bullinger, L.37
Rucker, F.G.38
Dohner, K.39
Dohner, H.40
Koster, J.41
Molenaar, J.J.42
Versteeg, R.43
Kool, M.44
Tabori, U.45
Malkin, D.46
Korshunov, A.47
Taylor, M.D.48
Lichter, P.49
Pfister, S.M.50
Korbel, J.O.51
more..
-
35
-
-
0023898435
-
Heterogeneity of genomic fusion of BCR and ABL in Philadelphia chromosome-positive acute lymphoblastic leukemia
-
Rubin CM, Carrino JJ, Dickler MN, Leibowitz D, Smith SD, Westbrook CA. 1988. Heterogeneity of genomic fusion of BCR and ABL in Philadelphia chromosome-positive acute lymphoblastic leukemia. Proc Natl Acad Sci USA 85: 2795-2799.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 2795-2799
-
-
Rubin, C.M.1
Carrino, J.J.2
Dickler, M.N.3
Leibowitz, D.4
Smith, S.D.5
Westbrook, C.A.6
-
36
-
-
70349969478
-
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
-
Shah SP, Morin RD, Khattra J, Prentice L, Pugh T, Burleigh A, Delaney A, Gelmon K, Guliany R, Senz J, Steidl C, Holt RA, Jones S, Sun M, Leung G, Moore R, Severson T, Taylor GA, Teschendorff AE, Tse K, Turashvili G, Varhol R, Warren RL, Watson P, Zhao Y, Caldas C, Huntsman D, Hirst M, Marra MA, Aparicio S. 2009. Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature 461: 809-813.
-
(2009)
Nature
, vol.461
, pp. 809-813
-
-
Shah, S.P.1
Morin, R.D.2
Khattra, J.3
Prentice, L.4
Pugh, T.5
Burleigh, A.6
Delaney, A.7
Gelmon, K.8
Guliany, R.9
Senz, J.10
Steidl, C.11
Holt, R.A.12
Jones, S.13
Sun, M.14
Leung, G.15
Moore, R.16
Severson, T.17
Taylor, G.A.18
Teschendorff, A.E.19
Tse, K.20
Turashvili, G.21
Varhol, R.22
Warren, R.L.23
Watson, P.24
Zhao, Y.25
Caldas, C.26
Huntsman, D.27
Hirst, M.28
Marra, M.A.29
Aparicio, S.30
more..
-
37
-
-
72949119310
-
Complex landscapes of somatic rearrangement in human breast cancer genomes
-
Stephens PJ, McBride DJ, Lin ML, Varela I, Pleasance ED, Simpson JT, Stebbings LA, Leroy C, Edkins S, Mudie LJ, Greenman CD, Jia M, Latimer C, Teague JW, Lau KW, Burton J, Quail MA, Swerdlow H, Churcher C, Natrajan R, Sieuwerts AM, Martens JW, Silver DP, Langerod A, Russnes HE, Foekens JA, Reis-Filho JS, van 't Veer L, Richardson AL, Borresen-Dale AL, Campbell PJ, Futreal PA, Stratton MR. 2009. Complex landscapes of somatic rearrangement in human breast cancer genomes. Nature 462: 1005-1010.
-
(2009)
Nature
, vol.462
, pp. 1005-1010
-
-
Stephens, P.J.1
McBride, D.J.2
Lin, M.L.3
Varela, I.4
Pleasance, E.D.5
Simpson, J.T.6
Stebbings, L.A.7
Leroy, C.8
Edkins, S.9
Mudie, L.J.10
Greenman, C.D.11
Jia, M.12
Latimer, C.13
Teague, J.W.14
Lau, K.W.15
Burton, J.16
Quail, M.A.17
Swerdlow, H.18
Churcher, C.19
Natrajan, R.20
Sieuwerts, A.M.21
Martens, J.W.22
Silver, D.P.23
Langerod, A.24
Russnes, H.E.25
Foekens, J.A.26
Reis-Filho, J.S.27
van 't Veer, L.28
Richardson, A.L.29
Borresen-Dale, A.L.30
Campbell, P.J.31
Futreal, P.A.32
Stratton, M.R.33
more..
-
38
-
-
78650959663
-
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
-
Stephens PJ, Greenman CD, Fu B, Yang F, Bignell GR, Mudie LJ, Pleasance ED, Lau KW, Beare D, Stebbings LA, McLaren S, Lin ML, McBride DJ, Varela I, Nik-Zainal S, Leroy C, Jia M, Menzies A, Butler AP, Teague JW, Quail MA, Burton J, Swerdlow H, Carter NP, Morsberger LA, Iacobuzio-Donahue C, Follows GA, Green AR, Flanagan AM, Stratton MR, Futreal PA, Campbell PJ. 2011. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 144: 27-40.
-
(2011)
Cell
, vol.144
, pp. 27-40
-
-
Stephens, P.J.1
Greenman, C.D.2
Fu, B.3
Yang, F.4
Bignell, G.R.5
Mudie, L.J.6
Pleasance, E.D.7
Lau, K.W.8
Beare, D.9
Stebbings, L.A.10
McLaren, S.11
Lin, M.L.12
McBride, D.J.13
Varela, I.14
Nik-Zainal, S.15
Leroy, C.16
Jia, M.17
Menzies, A.18
Butler, A.P.19
Teague, J.W.20
Quail, M.A.21
Burton, J.22
Swerdlow, H.23
Carter, N.P.24
Morsberger, L.A.25
Iacobuzio-Donahue, C.26
Follows, G.A.27
Green, A.R.28
Flanagan, A.M.29
Stratton, M.R.30
Futreal, P.A.31
Campbell, P.J.32
more..
-
39
-
-
77954255681
-
Integrative genomic profiling of human prostate cancer
-
Taylor BS, Schultz N, Hieronymus H, Gopalan A, Xiao Y, Carver BS, Arora VK, Kaushik P, Cerami E, Reva B, Antipin Y, Mitsiades N, Landers T, Dolgalev I, Major JE, Wilson M, Socci ND, Lash AE, Heguy A, Eastham JA, Scher HI, Reuter VE, Scardino PT, Sander C, Sawyers CL, Gerald WL. 2010. Integrative genomic profiling of human prostate cancer. Cancer Cell 18: 11-22.
-
(2010)
Cancer Cell
, vol.18
, pp. 11-22
-
-
Taylor, B.S.1
Schultz, N.2
Hieronymus, H.3
Gopalan, A.4
Xiao, Y.5
Carver, B.S.6
Arora, V.K.7
Kaushik, P.8
Cerami, E.9
Reva, B.10
Antipin, Y.11
Mitsiades, N.12
Landers, T.13
Dolgalev, I.14
Major, J.E.15
Wilson, M.16
Socci, N.D.17
Lash, A.E.18
Heguy, A.19
Eastham, J.A.20
Scher, H.I.21
Reuter, V.E.22
Scardino, P.T.23
Sander, C.24
Sawyers, C.L.25
Gerald, W.L.26
more..
-
40
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, Varambally S, Cao X, Tchinda J, Kuefer R, Lee C, Montie JE, Shah RB, Pienta KJ, Rubin MA, Chinnaiyan AM. 2005. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310: 644-648.
-
(2005)
Science
, vol.310
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
Sun, X.W.6
Varambally, S.7
Cao, X.8
Tchinda, J.9
Kuefer, R.10
Lee, C.11
Montie, J.E.12
Shah, R.B.13
Pienta, K.J.14
Rubin, M.A.15
Chinnaiyan, A.M.16
-
41
-
-
34547642493
-
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
-
Tomlins SA, Laxman B, Dhanasekaran SM, Helgeson BE, Cao X, Morris DS, Menon A, Jing X, Cao Q, Han B, Yu J, Wang L, Montie JE, Rubin MA, Pienta KJ, Roulston D, Shah RB, Varambally S, Mehra R, Chinnaiyan AM. 2007. Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature 448: 595-599.
-
(2007)
Nature
, vol.448
, pp. 595-599
-
-
Tomlins, S.A.1
Laxman, B.2
Dhanasekaran, S.M.3
Helgeson, B.E.4
Cao, X.5
Morris, D.S.6
Menon, A.7
Jing, X.8
Cao, Q.9
Han, B.10
Yu, J.11
Wang, L.12
Montie, J.E.13
Rubin, M.A.14
Pienta, K.J.15
Roulston, D.16
Shah, R.B.17
Varambally, S.18
Mehra, R.19
Chinnaiyan, A.M.20
more..
-
42
-
-
39049150843
-
Role of the TMPRSS2-ERG gene fusion in prostate cancer
-
Tomlins SA, Laxman B, Varambally S, Cao X, Yu J, Helgeson BE, Cao Q, Prensner JR, Rubin MA, Shah RB, Mehra R, Chinnaiyan AM. 2008. Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia 10: 177-188.
-
(2008)
Neoplasia
, vol.10
, pp. 177-188
-
-
Tomlins, S.A.1
Laxman, B.2
Varambally, S.3
Cao, X.4
Yu, J.5
Helgeson, B.E.6
Cao, Q.7
Prensner, J.R.8
Rubin, M.A.9
Shah, R.B.10
Mehra, R.11
Chinnaiyan, A.M.12
-
43
-
-
65449136284
-
TopHat: Discovering splice junctions with RNA-Seq
-
Trapnell C, Pachter L, Salzberg SL. 2009. TopHat: Discovering splice junctions with RNA-Seq. Bioinformatics 25: 1105-1111.
-
(2009)
Bioinformatics
, vol.25
, pp. 1105-1111
-
-
Trapnell, C.1
Pachter, L.2
Salzberg, S.L.3
-
44
-
-
0037934515
-
End-sequence profiling: Sequence-based analysis of aberrant genomes
-
Volik S, Zhao S, Chin K, Brebner JH, Herndon DR, Tao Q, Kowbel D, Huang G, Lapuk A, Kuo WL, Magrane G, De Jong P, Gray JW, Collins C. 2003. End-sequence profiling: Sequence-based analysis of aberrant genomes. Proc Natl Acad Sci USA 100: 7696-7701.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7696-7701
-
-
Volik, S.1
Zhao, S.2
Chin, K.3
Brebner, J.H.4
Herndon, D.R.5
Tao, Q.6
Kowbel, D.7
Huang, G.8
Lapuk, A.9
Kuo, W.L.10
Magrane, G.11
De Jong, P.12
Gray, J.W.13
Collins, C.14
-
45
-
-
33644653015
-
Decoding the fine-scale structure of a breast cancer genome and transcriptome
-
Volik S, Raphael BJ, Huang G, Stratton MR, Bignel G, Murnane J, Brebner JH, Bajsarowicz K, Paris PL, Tao Q, Kowbel D, Lapuk A, Shagin DA, Shagina IA, Gray JW, Cheng JF, de Jong PJ, Pevzner P, Collins C. 2006. Decoding the fine-scale structure of a breast cancer genome and transcriptome. Genome Res 16: 394-404.
-
(2006)
Genome Res
, vol.16
, pp. 394-404
-
-
Volik, S.1
Raphael, B.J.2
Huang, G.3
Stratton, M.R.4
Bignel, G.5
Murnane, J.6
Brebner, J.H.7
Bajsarowicz, K.8
Paris, P.L.9
Tao, Q.10
Kowbel, D.11
Lapuk, A.12
Shagin, D.A.13
Shagina, I.A.14
Gray, J.W.15
Cheng, J.F.16
de Jong, P.J.17
Pevzner, P.18
Collins, C.19
-
46
-
-
77956534324
-
ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data
-
Wang K, Li M, Hakonarson H. 2010. ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data. Nucleic acids research 38: e164-e164.
-
(2010)
Nucleic acids research
, vol.38
-
-
Wang, K.1
Li, M.2
Hakonarson, H.3
-
47
-
-
80053584635
-
MicroRNAs associated with metastatic prostate cancer
-
Watahiki A, Wang Y, Morris J, Dennis K, O'Dwyer HM, Gleave M, Gout PW. 2011. MicroRNAs associated with metastatic prostate cancer. PLoS One 6: e24950.
-
(2011)
PLoS One
, vol.6
-
-
Watahiki, A.1
Wang, Y.2
Morris, J.3
Dennis, K.4
O'Dwyer, H.M.5
Gleave, M.6
Gout, P.W.7
-
48
-
-
84975810758
-
Integrated genome and transcriptome sequencing identifies a novel form of hybrid and aggressive prostate cancer
-
Wu C, Wyatt AW, Lapuk AV, McPherson A, McConeghy BJ, Bell RH, Anderson S, Haegert A, Brahmbhatt S, Shukin R, Mo F, Li E, Fazli L, Hurtado-Coll A, Jones EC, Butterfield YS, Hach F, Hormozdiari F, Hajirasouliha I, Boutros PC, Bristow RG, Jones SJ, Hirst M, Marra MA, Maher CA, Chinnaiyan AM, Sahinalp SC, Gleave ME, Volik SV, Collins CC. 2012. Integrated genome and transcriptome sequencing identifies a novel form of hybrid and aggressive prostate cancer. J Pathol 227: 53-61.
-
(2012)
J Pathol
, vol.227
, pp. 53-61
-
-
Wu, C.1
Wyatt, A.W.2
Lapuk, A.V.3
McPherson, A.4
McConeghy, B.J.5
Bell, R.H.6
Anderson, S.7
Haegert, A.8
Brahmbhatt, S.9
Shukin, R.10
Mo, F.11
Li, E.12
Fazli, L.13
Hurtado-Coll, A.14
Jones, E.C.15
Butterfield, Y.S.16
Hach, F.17
Hormozdiari, F.18
Hajirasouliha, I.19
Boutros, P.C.20
Bristow, R.G.21
Jones, S.J.22
Hirst, M.23
Marra, M.A.24
Maher, C.A.25
Chinnaiyan, A.M.26
Sahinalp, S.C.27
Gleave, M.E.28
Volik, S.V.29
Collins, C.C.30
more..
-
49
-
-
84862907593
-
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
-
Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford D, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE, Pui CH, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG. 2012. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature 481: 157-163.
-
(2012)
Nature
, vol.481
, pp. 157-163
-
-
Zhang, J.1
Ding, L.2
Holmfeldt, L.3
Wu, G.4
Heatley, S.L.5
Payne-Turner, D.6
Easton, J.7
Chen, X.8
Wang, J.9
Rusch, M.10
Lu, C.11
Chen, S.C.12
Wei, L.13
Collins-Underwood, J.R.14
Ma, J.15
Roberts, K.G.16
Pounds, S.B.17
Ulyanov, A.18
Becksfort, J.19
Gupta, P.20
Huether, R.21
Kriwacki, R.W.22
Parker, M.23
McGoldrick, D.J.24
Zhao, D.25
Alford, D.26
Espy, S.27
Bobba, K.C.28
Song, G.29
Pei, D.30
Cheng, C.31
Roberts, S.32
Barbato, M.I.33
Campana, D.34
Coustan-Smith, E.35
Shurtleff, S.A.36
Raimondi, S.C.37
Kleppe, M.38
Cools, J.39
Shimano, K.A.40
Hermiston, M.L.41
Doulatov, S.42
Eppert, K.43
Laurenti, E.44
Notta, F.45
Dick, J.E.46
Basso, G.47
Hunger, S.P.48
Loh, M.L.49
Devidas, M.50
Wood, B.51
Winter, S.52
Dunsmore, K.P.53
Fulton, R.S.54
Fulton, L.L.55
Hong, X.56
Harris, C.C.57
Dooling, D.J.58
Ochoa, K.59
Johnson, K.J.60
Obenauer, J.C.61
Evans, W.E.62
Pui, C.H.63
Naeve, C.W.64
Ley, T.J.65
Mardis, E.R.66
Wilson, R.K.67
Downing, J.R.68
Mullighan, C.G.69
more..
|