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Volumn 11, Issue 10, 2012, Pages 811-822

Functional characterization of the Caenorhabditis elegans DNA repair enzyme APN-1

Author keywords

AP endonuclease; Base excision repair; C. elegans; DNA repair; Mutations; Oxidative DNA damage

Indexed keywords

AMINO ACID; APN 1 ENZYME; CAENORHABDITIS ELEGANS PROTEIN; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; EXODEOXYRIBONUCLEASE III; EXODEOXYRIBONUCLEASE V; HYBRID PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; UNCLASSIFIED DRUG; ZINC ION;

EID: 84867218574     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2012.06.009     Document Type: Article
Times cited : (18)

References (35)
  • 1
    • 78649335598 scopus 로고    scopus 로고
    • The endonuclease IV family of apurinic/apyrimidinic endonucleases
    • Daley J.M., Zakaria C., Ramotar D. The endonuclease IV family of apurinic/apyrimidinic endonucleases. Mutat. Res. 2010, 705:217-227.
    • (2010) Mutat. Res. , vol.705 , pp. 217-227
    • Daley, J.M.1    Zakaria, C.2    Ramotar, D.3
  • 2
    • 0025864553 scopus 로고
    • Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation
    • Ramotar D., Popoff S.C., Gralla E.B., Demple B. Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation. Mol. Cell. Biol. 1991, 11:4537-4544.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4537-4544
    • Ramotar, D.1    Popoff, S.C.2    Gralla, E.B.3    Demple, B.4
  • 3
    • 0042732955 scopus 로고    scopus 로고
    • The role of yeast DNA 3'-phosphatase Tpp1 and rad1/Rad10 endonuclease in processing spontaneous and induced base lesions
    • Karumbati A.S., Deshpande R.A., Jilani A., Vance J.R., Ramotar D., Wilson T.E. The role of yeast DNA 3'-phosphatase Tpp1 and rad1/Rad10 endonuclease in processing spontaneous and induced base lesions. J. Biol. Chem. 2003, 278:31434-31443.
    • (2003) J. Biol. Chem. , vol.278 , pp. 31434-31443
    • Karumbati, A.S.1    Deshpande, R.A.2    Jilani, A.3    Vance, J.R.4    Ramotar, D.5    Wilson, T.E.6
  • 4
    • 22544450152 scopus 로고    scopus 로고
    • The 3'→5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae
    • Ishchenko A.A., Yang X., Ramotar D., Saparbaev M. The 3'→5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae. Mol. Cell. Biol. 2005, 25:6380-6390.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 6380-6390
    • Ishchenko, A.A.1    Yang, X.2    Ramotar, D.3    Saparbaev, M.4
  • 5
    • 1242320312 scopus 로고    scopus 로고
    • The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway
    • Gros L., Ishchenko A.A., Ide H., Elder R.H., Saparbaev M.K. The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway. Nucleic Acids Res. 2004, 32:73-81.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 73-81
    • Gros, L.1    Ishchenko, A.A.2    Ide, H.3    Elder, R.H.4    Saparbaev, M.K.5
  • 6
    • 0037049975 scopus 로고    scopus 로고
    • Alternative nucleotide incision repair pathway for oxidative DNA damage
    • Ischenko A.A., Saparbaev M.K. Alternative nucleotide incision repair pathway for oxidative DNA damage. Nature 2002, 415:183-187.
    • (2002) Nature , vol.415 , pp. 183-187
    • Ischenko, A.A.1    Saparbaev, M.K.2
  • 7
    • 0031296962 scopus 로고    scopus 로고
    • The apurinic-apyrimidinic endonuclease IV family of DNA repair enzymes
    • Ramotar D. The apurinic-apyrimidinic endonuclease IV family of DNA repair enzymes. Biochem. Cell Biol. 1997, 75:327-336.
    • (1997) Biochem. Cell Biol. , vol.75 , pp. 327-336
    • Ramotar, D.1
  • 8
    • 0030004921 scopus 로고    scopus 로고
    • Functional expression of Escherichia coli endonuclease IV in apurinic endonuclease-deficient yeast
    • Ramotar D., Demple B. Functional expression of Escherichia coli endonuclease IV in apurinic endonuclease-deficient yeast. J. Biol. Chem. 1996, 271:7368-7374.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7368-7374
    • Ramotar, D.1    Demple, B.2
  • 9
    • 0025975106 scopus 로고
    • Complementation of DNA repair-deficient Escherichia coli by the yeast Apn1 apurinic/apyrimidinic endonuclease gene
    • Ramotar D., Popoff S.C., Demple B. Complementation of DNA repair-deficient Escherichia coli by the yeast Apn1 apurinic/apyrimidinic endonuclease gene. Mol. Microbiol. 1991, 5:149-155.
    • (1991) Mol. Microbiol. , vol.5 , pp. 149-155
    • Ramotar, D.1    Popoff, S.C.2    Demple, B.3
  • 10
    • 0038687158 scopus 로고    scopus 로고
    • Characterization of two independent amino acid substitutions that disrupt the DNA repair functions of the yeast Apn1
    • Jilani A., Vongsamphanh R., Leduc A., Gros L., Saparbaev M., Ramotar D. Characterization of two independent amino acid substitutions that disrupt the DNA repair functions of the yeast Apn1. Biochemistry 2003, 42:6436-6445.
    • (2003) Biochemistry , vol.42 , pp. 6436-6445
    • Jilani, A.1    Vongsamphanh, R.2    Leduc, A.3    Gros, L.4    Saparbaev, M.5    Ramotar, D.6
  • 11
    • 0033596896 scopus 로고    scopus 로고
    • Characterization of amino acid substitutions that severely alter the DNA repair functions of Escherichia coli endonuclease IV
    • Yang X., Tellier P., Masson J.Y., Vu T., Ramotar D. Characterization of amino acid substitutions that severely alter the DNA repair functions of Escherichia coli endonuclease IV. Biochemistry 1999, 38:3615-3623.
    • (1999) Biochemistry , vol.38 , pp. 3615-3623
    • Yang, X.1    Tellier, P.2    Masson, J.Y.3    Vu, T.4    Ramotar, D.5
  • 12
    • 19344378245 scopus 로고    scopus 로고
    • Identification of two apurinic/apyrimidinic endonucleases from Caenorhabditis elegans by cross-species complementation
    • Shatilla A., Leduc A., Yang X., Ramotar D. Identification of two apurinic/apyrimidinic endonucleases from Caenorhabditis elegans by cross-species complementation. DNA Repair (Amst.) 2005, 4:655-670.
    • (2005) DNA Repair (Amst.) , vol.4 , pp. 655-670
    • Shatilla, A.1    Leduc, A.2    Yang, X.3    Ramotar, D.4
  • 13
    • 0035805515 scopus 로고    scopus 로고
    • Uncoupling of 3'-phosphatase and 5'-kinase functions in budding yeast. Characterization of Saccharomyces cerevisiae DNA 3'-phosphatase (TPP1)
    • Vance J.R., Wilson T.E. Uncoupling of 3'-phosphatase and 5'-kinase functions in budding yeast. Characterization of Saccharomyces cerevisiae DNA 3'-phosphatase (TPP1). J. Biol. Chem. 2001, 276:15073-15081.
    • (2001) J. Biol. Chem. , vol.276 , pp. 15073-15081
    • Vance, J.R.1    Wilson, T.E.2
  • 15
    • 25444515395 scopus 로고    scopus 로고
    • Characterization of Caenorhabditis elegans exonuclease-3 and evidence that a Mg(2+)-dependent variant exhibits a distinct mode of action on damaged DNA
    • Shatilla A., Ishchenko A.A., Saparbaev M., Ramotar D. Characterization of Caenorhabditis elegans exonuclease-3 and evidence that a Mg(2+)-dependent variant exhibits a distinct mode of action on damaged DNA. Biochemistry 2005, 44:12835-12848.
    • (2005) Biochemistry , vol.44 , pp. 12835-12848
    • Shatilla, A.1    Ishchenko, A.A.2    Saparbaev, M.3    Ramotar, D.4
  • 16
    • 0037101779 scopus 로고    scopus 로고
    • Embryonic extracts derived from the nematode Caenorhabditis elegans remove uracil from DNA by the sequential action of uracil-DNA glycosylase and AP (apurinic/apyrimidinic) endonuclease
    • Shatilla A., Ramotar D. Embryonic extracts derived from the nematode Caenorhabditis elegans remove uracil from DNA by the sequential action of uracil-DNA glycosylase and AP (apurinic/apyrimidinic) endonuclease. Biochem. J. 2002, 365:547-553.
    • (2002) Biochem. J. , vol.365 , pp. 547-553
    • Shatilla, A.1    Ramotar, D.2
  • 17
    • 0030583735 scopus 로고    scopus 로고
    • The Caenorhabditis elegans gene CeAPN1 encodes a homolog of Escherichia coli and yeast apurinic/apyrimidinic endonuclease
    • Masson J.Y., Tremblay S., Ramotar D. The Caenorhabditis elegans gene CeAPN1 encodes a homolog of Escherichia coli and yeast apurinic/apyrimidinic endonuclease. Gene 1996, 179:291-293.
    • (1996) Gene , vol.179 , pp. 291-293
    • Masson, J.Y.1    Tremblay, S.2    Ramotar, D.3
  • 18
    • 0030911140 scopus 로고    scopus 로고
    • Normal processing of AP sites in Apn1-deficient Saccharomyces cerevisiae is restored by Escherichia coli genes expressing either exonuclease III or endonuclease III
    • Masson J.Y., Ramotar D. Normal processing of AP sites in Apn1-deficient Saccharomyces cerevisiae is restored by Escherichia coli genes expressing either exonuclease III or endonuclease III. Mol. Microbiol. 1997, 24:711-721.
    • (1997) Mol. Microbiol. , vol.24 , pp. 711-721
    • Masson, J.Y.1    Ramotar, D.2
  • 19
    • 0345305364 scopus 로고    scopus 로고
    • Characterisation of new substrate specificities of Escherichia coli and Saccharomyces cerevisiae AP endonucleases
    • Ishchenko A.A., Sanz G., Privezentzev C.V., Maksimenko A.V., Saparbaev M. Characterisation of new substrate specificities of Escherichia coli and Saccharomyces cerevisiae AP endonucleases. Nucleic Acids Res. 2003, 31:6344-6353.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 6344-6353
    • Ishchenko, A.A.1    Sanz, G.2    Privezentzev, C.V.3    Maksimenko, A.V.4    Saparbaev, M.5
  • 20
    • 77957879524 scopus 로고    scopus 로고
    • Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity
    • Gelin A., Redrejo-Rodriguez M., Laval J., Fedorova O.S., Saparbaev M., Ishchenko A.A. Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity. PLoS One 2010, 5:e12241.
    • (2010) PLoS One , vol.5
    • Gelin, A.1    Redrejo-Rodriguez, M.2    Laval, J.3    Fedorova, O.S.4    Saparbaev, M.5    Ishchenko, A.A.6
  • 21
    • 0032190633 scopus 로고    scopus 로고
    • Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites
    • Johnson R.E., Torres-Ramos C.A., Izumi T., Mitra S., Prakash S., Prakash L. Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites. Genes Dev. 1998, 12:3137-3143.
    • (1998) Genes Dev. , vol.12 , pp. 3137-3143
    • Johnson, R.E.1    Torres-Ramos, C.A.2    Izumi, T.3    Mitra, S.4    Prakash, S.5    Prakash, L.6
  • 22
    • 0029990930 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae IMP2 gene encodes a transcriptional activator that mediates protection against DNA damage caused by bleomycin and other oxidants
    • Masson J.Y., Ramotar D. The Saccharomyces cerevisiae IMP2 gene encodes a transcriptional activator that mediates protection against DNA damage caused by bleomycin and other oxidants. Mol. Cell. Biol. 1996, 16:2091-2100.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2091-2100
    • Masson, J.Y.1    Ramotar, D.2
  • 23
    • 0033529716 scopus 로고    scopus 로고
    • Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis
    • Hosfield D.J., Guan Y., Haas B.J., Cunningham R.P., Tainer J.A. Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis. Cell 1999, 98:397-408.
    • (1999) Cell , vol.98 , pp. 397-408
    • Hosfield, D.J.1    Guan, Y.2    Haas, B.J.3    Cunningham, R.P.4    Tainer, J.A.5
  • 24
    • 0042622380 scopus 로고    scopus 로고
    • SWISS-MODEL: an automated protein homology-modeling server
    • Schwede T., Kopp J., Guex N., Peitsch M.C. SWISS-MODEL: an automated protein homology-modeling server. Nucleic Acids Res. 2003, 31:3381-3385.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 3381-3385
    • Schwede, T.1    Kopp, J.2    Guex, N.3    Peitsch, M.C.4
  • 26
    • 0025830469 scopus 로고
    • A method to identify protein sequences that fold into a known three-dimensional structure
    • Bowie J.U., Luthy R., Eisenberg D. A method to identify protein sequences that fold into a known three-dimensional structure. Science 1991, 253:164-170.
    • (1991) Science , vol.253 , pp. 164-170
    • Bowie, J.U.1    Luthy, R.2    Eisenberg, D.3
  • 27
    • 0026610767 scopus 로고
    • Assessment of protein models with three-dimensional profiles
    • Luthy R., Bowie J.U., Eisenberg D. Assessment of protein models with three-dimensional profiles. Nature 1992, 356:83-85.
    • (1992) Nature , vol.356 , pp. 83-85
    • Luthy, R.1    Bowie, J.U.2    Eisenberg, D.3
  • 28
    • 3042683893 scopus 로고    scopus 로고
    • EF-site and PDBjViewer: database and viewer for protein functional sites
    • Kinoshita K., Nakamura H. eF-site and PDBjViewer: database and viewer for protein functional sites. Bioinformatics 2004, 20:1329-1330.
    • (2004) Bioinformatics , vol.20 , pp. 1329-1330
    • Kinoshita, K.1    Nakamura, H.2
  • 29
    • 0034785884 scopus 로고    scopus 로고
    • Repair of DNA strand breaks by the overlapping functions of lesion-specific and non-lesion-specific DNA 3' phosphatases
    • Vance J.R., Wilson T.E. Repair of DNA strand breaks by the overlapping functions of lesion-specific and non-lesion-specific DNA 3' phosphatases. Mol. Cell. Biol. 2001, 21:7191-7198.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 7191-7198
    • Vance, J.R.1    Wilson, T.E.2
  • 30
    • 10044225990 scopus 로고    scopus 로고
    • Alpha-anomeric deoxynucleotides, anoxic products of ionizing radiation, are substrates for the endonuclease IV-type AP endonucleases
    • Ishchenko A.A., Ide H., Ramotar D., Nevinsky G., Saparbaev M. Alpha-anomeric deoxynucleotides, anoxic products of ionizing radiation, are substrates for the endonuclease IV-type AP endonucleases. Biochemistry 2004, 43:15210-15216.
    • (2004) Biochemistry , vol.43 , pp. 15210-15216
    • Ishchenko, A.A.1    Ide, H.2    Ramotar, D.3    Nevinsky, G.4    Saparbaev, M.5
  • 31
    • 0035137178 scopus 로고    scopus 로고
    • Pir1p mediates translocation of the yeast Apn1p endonuclease into the mitochondria to maintain genomic stability
    • Vongsamphanh R., Fortier P.K., Ramotar D. Pir1p mediates translocation of the yeast Apn1p endonuclease into the mitochondria to maintain genomic stability. Mol. Cell. Biol. 2001, 21:1647-1655.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1647-1655
    • Vongsamphanh, R.1    Fortier, P.K.2    Ramotar, D.3
  • 32
    • 82955241476 scopus 로고    scopus 로고
    • NDX-1 protein hydrolyzes 8-oxo-7, 8-dihydrodeoxyguanosine-5'-diphosphate to sanitize oxidized nucleotides and prevent oxidative stress in Caenorhabditis elegans
    • Sanada U., Yonekura S., Kikuchi M., Hashiguchi K., Nakamura N., Yonei S., Zhang-Akiyama Q.M. NDX-1 protein hydrolyzes 8-oxo-7, 8-dihydrodeoxyguanosine-5'-diphosphate to sanitize oxidized nucleotides and prevent oxidative stress in Caenorhabditis elegans. J. Biochem. 2011, 150:649-657.
    • (2011) J. Biochem. , vol.150 , pp. 649-657
    • Sanada, U.1    Yonekura, S.2    Kikuchi, M.3    Hashiguchi, K.4    Nakamura, N.5    Yonei, S.6    Zhang-Akiyama, Q.M.7
  • 35
    • 33846799362 scopus 로고    scopus 로고
    • Unraveling the three-metal-ion catalytic mechanism of the DNA repair enzyme endonuclease IV
    • Ivanov I., Tainer J.A., McCammon J.A. Unraveling the three-metal-ion catalytic mechanism of the DNA repair enzyme endonuclease IV. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:1465-1470.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 1465-1470
    • Ivanov, I.1    Tainer, J.A.2    McCammon, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.