Embryonic extracts derived from the nematode Caenorhabditis elegans remove uracil from DNA by the sequential action of uracil-DNA glycosylase and AP (apurinic/apyrimidinic) endonuclease

Biochemical Journal

Volumn 365, Issue 2, 2002, Pages 547-553

  Shatilla, Andrea ^a   Ramotar, Dindial ^a  

^a MAISONNEUVE ROSEMONT HOSPITAL   (Canada)

Author keywords

Abasic site; Base lesion; Cytosine deamination; Exonuclease; Glycosylase inhibitor

Indexed keywords

ENZYMES; MAGNESIUM PRINTING PLATES; SUBSTRATES; SUGARS;

EMBRYONIC EXTRACTS;

DNA;

DNA; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; GUANINE; MAGNESIUM ION; OLIGONUCLEOTIDE; PHOSPHORUS 32; THYMINE; URACIL; URACIL DNA GLYCOSYLTRANSFERASE;

ALKYLATION; APYRIMIDINIC SITE; ARTICLE; BACILLUS SUBTILIS; CAENORHABDITIS ELEGANS; CATALYSIS; CHEMICAL BOND; CONTROLLED STUDY; DEAMINATION; DNA MODIFICATION; EMBRYO; ENZYME ACTIVITY; ENZYME ISOLATION; ENZYME MECHANISM; EXCISION REPAIR; MUTAGENESIS; NEMATODE; NONHUMAN; OXIDATION; PRIORITY JOURNAL;

ANIMALS; BASE SEQUENCE; CAENORHABDITIS ELEGANS; CARBON-OXYGEN LYASES; DNA; DNA GLYCOSYLASES; DNA PRIMERS; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; EMBRYO, NONMAMMALIAN; HYDROLYSIS; N-GLYCOSYL HYDROLASES; SUBSTRATE SPECIFICITY; URACIL; URACIL-DNA GLYCOSIDASE;

BACILLUS SUBTILIS; CAENORHABDITIS; CAENORHABDITIS ELEGANS; INVERTEBRATA;

EID: 0037101779     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020375     Document Type: Article

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