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Volumn 11, Issue 10, 2012, Pages 799-810

SUMO ligase activity of vertebrate Mms21/Nse2 is required for efficient DNA repair but not for Smc5/6 complex stability

Author keywords

DNA repair; DT40; Nse2; SMC proteins; SUMO ligase

Indexed keywords

CISPLATIN; PROTEIN MMS21; PROTEIN NSE2; PROTEIN SMC5; PROTEIN SMC6; SUMO LIGASE; SUMO PROTEIN; UNCLASSIFIED DRUG;

EID: 84867197437     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2012.06.010     Document Type: Article
Times cited : (13)

References (56)
  • 1
    • 22344439942 scopus 로고    scopus 로고
    • Dynamic molecular linkers of the genome: the first decade of SMC proteins
    • Losada A., Hirano T. Dynamic molecular linkers of the genome: the first decade of SMC proteins. Genes Dev. 2005, 19:1269-1287.
    • (2005) Genes Dev. , vol.19 , pp. 1269-1287
    • Losada, A.1    Hirano, T.2
  • 2
    • 33646177549 scopus 로고    scopus 로고
    • At the heart of the chromosome: SMC proteins in action
    • Hirano T. At the heart of the chromosome: SMC proteins in action. Nat. Rev. Mol. Cell Biol. 2006, 7:311-322.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 311-322
    • Hirano, T.1
  • 3
    • 73349127026 scopus 로고    scopus 로고
    • Cohesin: its roles and mechanisms
    • Nasmyth K., Haering C.H. Cohesin: its roles and mechanisms. Annu. Rev. Genet. 2009, 43:525-558.
    • (2009) Annu. Rev. Genet. , vol.43 , pp. 525-558
    • Nasmyth, K.1    Haering, C.H.2
  • 4
    • 22244481613 scopus 로고    scopus 로고
    • The structure and function of SMC and kleisin complexes
    • Nasmyth K., Haering C.H. The structure and function of SMC and kleisin complexes. Annu. Rev. Biochem. 2005, 74:595-648.
    • (2005) Annu. Rev. Biochem. , vol.74 , pp. 595-648
    • Nasmyth, K.1    Haering, C.H.2
  • 7
    • 16344370926 scopus 로고    scopus 로고
    • A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization
    • Zhao X., Blobel G. A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:4777-4782.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 4777-4782
    • Zhao, X.1    Blobel, G.2
  • 8
    • 33845985979 scopus 로고    scopus 로고
    • The Smc5-Smc6 DNA repair complex. Bridging of the Smc5-Smc6 heads by the KLEISIN, Nse4, and non-Kleisin subunits
    • Palecek J., Vidot S., Feng M., Doherty A.J., Lehmann A.R. The Smc5-Smc6 DNA repair complex. Bridging of the Smc5-Smc6 heads by the KLEISIN, Nse4, and non-Kleisin subunits. J. Biol. Chem. 2006, 281:36952-36959.
    • (2006) J. Biol. Chem. , vol.281 , pp. 36952-36959
    • Palecek, J.1    Vidot, S.2    Feng, M.3    Doherty, A.J.4    Lehmann, A.R.5
  • 10
    • 11144324990 scopus 로고    scopus 로고
    • Nse2 a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage
    • Andrews E.A., Palecek J., Sergeant J., Taylor E., Lehmann A.R., Watts F.Z. Nse2 a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage. Mol. Cell. Biol. 2005, 25:185-196.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 185-196
    • Andrews, E.A.1    Palecek, J.2    Sergeant, J.3    Taylor, E.4    Lehmann, A.R.5    Watts, F.Z.6
  • 11
    • 6344268940 scopus 로고    scopus 로고
    • Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex Nse3, play a crucial role in meiosis
    • Pebernard S., McDonald W.H., Pavlova Y., Yates J.R., Boddy M.N. Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex Nse3, play a crucial role in meiosis. Mol. Biol. Cell 2004, 15:4866-4876.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 4866-4876
    • Pebernard, S.1    McDonald, W.H.2    Pavlova, Y.3    Yates, J.R.4    Boddy, M.N.5
  • 12
    • 0028850628 scopus 로고
    • The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair
    • Lehmann A.R., Walicka M., Griffiths D.J., Murray J.M., Watts F.Z., McCready S., Carr A.M. The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair. Mol. Cell. Biol. 1995, 15:7067-7080.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 7067-7080
    • Lehmann, A.R.1    Walicka, M.2    Griffiths, D.J.3    Murray, J.M.4    Watts, F.Z.5    McCready, S.6    Carr, A.M.7
  • 13
    • 79953803643 scopus 로고    scopus 로고
    • Roles of vertebrate smc5 in sister chromatid cohesion and homologous recombinational repair
    • Stephan A.K., Kliszczak M., Dodson H., Cooley C., Morrison C.G. Roles of vertebrate smc5 in sister chromatid cohesion and homologous recombinational repair. Mol. Cell. Biol. 2011, 31:1369-1381.
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 1369-1381
    • Stephan, A.K.1    Kliszczak, M.2    Dodson, H.3    Cooley, C.4    Morrison, C.G.5
  • 14
    • 70849109889 scopus 로고    scopus 로고
    • The structural maintenance of chromosomes 5/6 complex promotes sister chromatid alignment and homologous recombination after DNA damage in Arabidopsis thaliana
    • Watanabe K., Pacher M., Dukowic S., Schubert V., Puchta H., Schubert I. The structural maintenance of chromosomes 5/6 complex promotes sister chromatid alignment and homologous recombination after DNA damage in Arabidopsis thaliana. Plant Cell 2009, 21:2688-2699.
    • (2009) Plant Cell , vol.21 , pp. 2688-2699
    • Watanabe, K.1    Pacher, M.2    Dukowic, S.3    Schubert, V.4    Puchta, H.5    Schubert, I.6
  • 15
    • 33746515537 scopus 로고    scopus 로고
    • Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks
    • Potts P.R., Porteus M.H., Yu H. Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks. EMBO J. 2006, 25:3377-3388.
    • (2006) EMBO J. , vol.25 , pp. 3377-3388
    • Potts, P.R.1    Porteus, M.H.2    Yu, H.3
  • 16
    • 38949143250 scopus 로고    scopus 로고
    • Identification of the proteins including MAGEG1, that make up the human SMC5-6 protein complex
    • Taylor E.M., Copsey A.C., Hudson J.J., Vidot S., Lehmann A.R. Identification of the proteins including MAGEG1, that make up the human SMC5-6 protein complex. Mol. Cell. Biol. 2008, 28:1197-1206.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 1197-1206
    • Taylor, E.M.1    Copsey, A.C.2    Hudson, J.J.3    Vidot, S.4    Lehmann, A.R.5
  • 20
    • 33750437743 scopus 로고    scopus 로고
    • Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks
    • Branzei D., Sollier J., Liberi G., Zhao X., Maeda D., Seki M., Enomoto T., Ohta K., Foiani M. Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks. Cell 2006, 127:509-522.
    • (2006) Cell , vol.127 , pp. 509-522
    • Branzei, D.1    Sollier, J.2    Liberi, G.3    Zhao, X.4    Maeda, D.5    Seki, M.6    Enomoto, T.7    Ohta, K.8    Foiani, M.9
  • 21
    • 33745217560 scopus 로고    scopus 로고
    • Chromosomal association of the Smc5/6 complex reveals that it functions in differently regulated pathways
    • Lindroos H.B., Strom L., Itoh T., Katou Y., Shirahige K., Sjogren C. Chromosomal association of the Smc5/6 complex reveals that it functions in differently regulated pathways. Mol. Cell 2006, 22:755-767.
    • (2006) Mol. Cell , vol.22 , pp. 755-767
    • Lindroos, H.B.1    Strom, L.2    Itoh, T.3    Katou, Y.4    Shirahige, K.5    Sjogren, C.6
  • 22
    • 77954186960 scopus 로고    scopus 로고
    • The Smc5/6 complex and Esc2 influence multiple replication-associated recombination processes in Saccharomyces cerevisiae
    • Choi K., Szakal B., Chen Y.H., Branzei D., Zhao X. The Smc5/6 complex and Esc2 influence multiple replication-associated recombination processes in Saccharomyces cerevisiae. Mol. Biol. Cell 2010, 21:2306-2314.
    • (2010) Mol. Biol. Cell , vol.21 , pp. 2306-2314
    • Choi, K.1    Szakal, B.2    Chen, Y.H.3    Branzei, D.4    Zhao, X.5
  • 23
    • 58749101522 scopus 로고    scopus 로고
    • Smc5/6 maintains stalled replication forks in a recombination-competent conformation
    • Irmisch A., Ampatzidou E., Mizuno K., O'Connell M.J., Murray J.M. Smc5/6 maintains stalled replication forks in a recombination-competent conformation. EMBO J. 2009, 28:144-155.
    • (2009) EMBO J. , vol.28 , pp. 144-155
    • Irmisch, A.1    Ampatzidou, E.2    Mizuno, K.3    O'Connell, M.J.4    Murray, J.M.5
  • 24
    • 77951230659 scopus 로고    scopus 로고
    • Sumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution
    • Chavez A., George V., Agrawal V., Johnson F.B. Sumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution. J. Biol. Chem. 2010, 285:11922-11930.
    • (2010) J. Biol. Chem. , vol.285 , pp. 11922-11930
    • Chavez, A.1    George, V.2    Agrawal, V.3    Johnson, F.B.4
  • 26
    • 68949154413 scopus 로고    scopus 로고
    • Smc5-Smc6-dependent removal of cohesin from mitotic chromosomes
    • Outwin E.A., Irmisch A., Murray J.M., O'Connell M.J. Smc5-Smc6-dependent removal of cohesin from mitotic chromosomes. Mol. Cell. Biol. 2009, 29:4363-4375.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 4363-4375
    • Outwin, E.A.1    Irmisch, A.2    Murray, J.M.3    O'Connell, M.J.4
  • 29
    • 63649144413 scopus 로고    scopus 로고
    • Principles of ubiquitin and SUMO modifications in DNA repair
    • Bergink S., Jentsch S. Principles of ubiquitin and SUMO modifications in DNA repair. Nature 2009, 458:461-467.
    • (2009) Nature , vol.458 , pp. 461-467
    • Bergink, S.1    Jentsch, S.2
  • 30
    • 3943099375 scopus 로고    scopus 로고
    • Protein modification by SUMO
    • Johnson E.S. Protein modification by SUMO. Annu. Rev. Biochem. 2004, 73:355-382.
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 355-382
    • Johnson, E.S.1
  • 31
    • 78649396592 scopus 로고    scopus 로고
    • The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
    • Gareau J.R., Lima C.D. The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition. Nat. Rev. Mol. Cell Biol. 2010, 11:861-871.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 861-871
    • Gareau, J.R.1    Lima, C.D.2
  • 33
    • 80052766372 scopus 로고    scopus 로고
    • The Nse2/Mms21 SUMO ligase of the Smc5/6 complex in the maintenance of genome stability
    • Stephan A.K., Kliszczak M., Morrison C.G. The Nse2/Mms21 SUMO ligase of the Smc5/6 complex in the maintenance of genome stability. FEBS Lett. 2011, 585:2907-2913.
    • (2011) FEBS Lett. , vol.585 , pp. 2907-2913
    • Stephan, A.K.1    Kliszczak, M.2    Morrison, C.G.3
  • 34
    • 0242413170 scopus 로고    scopus 로고
    • Novel essential DNA repair proteins Nse1 and Nse2 are subunits of the fission yeast Smc5-Smc6 complex
    • McDonald W.H., Pavlova Y., Yates J.R., Boddy M.N. Novel essential DNA repair proteins Nse1 and Nse2 are subunits of the fission yeast Smc5-Smc6 complex. J. Biol. Chem. 2003, 278:45460-45467.
    • (2003) J. Biol. Chem. , vol.278 , pp. 45460-45467
    • McDonald, W.H.1    Pavlova, Y.2    Yates, J.R.3    Boddy, M.N.4
  • 35
    • 57349094259 scopus 로고    scopus 로고
    • Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability
    • Pebernard S., Perry J.J., Tainer J.A., Boddy M.N. Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability. Mol. Biol. Cell 2008, 19:4099-4109.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 4099-4109
    • Pebernard, S.1    Perry, J.J.2    Tainer, J.A.3    Boddy, M.N.4
  • 36
    • 77956936946 scopus 로고    scopus 로고
    • MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases
    • Doyle J.M., Gao J., Wang J., Yang M., Potts P.R. MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases. Mol. Cell 2010, 39:963-974.
    • (2010) Mol. Cell , vol.39 , pp. 963-974
    • Doyle, J.M.1    Gao, J.2    Wang, J.3    Yang, M.4    Potts, P.R.5
  • 37
    • 36849070287 scopus 로고    scopus 로고
    • Requirement of Nse1 a subunit of the Smc5-Smc6 complex, for Rad52-dependent postreplication repair of UV-damaged DNA in Saccharomyces cerevisiae
    • Santa Maria S.R., Gangavarapu V., Johnson R.E., Prakash L., Prakash S. Requirement of Nse1 a subunit of the Smc5-Smc6 complex, for Rad52-dependent postreplication repair of UV-damaged DNA in Saccharomyces cerevisiae. Mol. Cell. Biol. 2007, 27:8409-8418.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 8409-8418
    • Santa Maria, S.R.1    Gangavarapu, V.2    Johnson, R.E.3    Prakash, L.4    Prakash, S.5
  • 38
    • 82655189983 scopus 로고    scopus 로고
    • Nse1-dependent recruitment of Smc5/6 to lesion-containing loci contributes to the repair defects of mutant complexes
    • Tapia-Alveal C., O'Connell M.J. Nse1-dependent recruitment of Smc5/6 to lesion-containing loci contributes to the repair defects of mutant complexes. Mol. Biol. Cell 2011, 22:4669-4682.
    • (2011) Mol. Biol. Cell , vol.22 , pp. 4669-4682
    • Tapia-Alveal, C.1    O'Connell, M.J.2
  • 39
    • 23344442009 scopus 로고    scopus 로고
    • Human MMS21/NSE2 is a SUMO ligase required for DNA repair
    • Potts P.R., Yu H. Human MMS21/NSE2 is a SUMO ligase required for DNA repair. Mol. Cell. Biol. 2005, 25:7021-7032.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 7021-7032
    • Potts, P.R.1    Yu, H.2
  • 41
    • 79954577310 scopus 로고    scopus 로고
    • SUMO-ligase activity of Mms21 is required for maintenance of chromosome integrity during the unperturbed mitotic cell division cycle in Saccharomyces cerevisiae
    • Rai R., Varma S.P., Shinde N., Ghosh S., Kumaran S.P., Skariah G., Laloraya S. SUMO-ligase activity of Mms21 is required for maintenance of chromosome integrity during the unperturbed mitotic cell division cycle in Saccharomyces cerevisiae. J. Biol. Chem. 2011, 286:14516-14530.
    • (2011) J. Biol. Chem. , vol.286 , pp. 14516-14530
    • Rai, R.1    Varma, S.P.2    Shinde, N.3    Ghosh, S.4    Kumaran, S.P.5    Skariah, G.6    Laloraya, S.7
  • 42
    • 0032530658 scopus 로고    scopus 로고
    • Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
    • Takata M., Sasaki M.S., Sonoda E., Morrison C., Hashimoto M., Utsumi H., Yamaguchi-Iwai Y., Shinohara A., Takeda S. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J. 1998, 17:5497-5508.
    • (1998) EMBO J. , vol.17 , pp. 5497-5508
    • Takata, M.1    Sasaki, M.S.2    Sonoda, E.3    Morrison, C.4    Hashimoto, M.5    Utsumi, H.6    Yamaguchi-Iwai, Y.7    Shinohara, A.8    Takeda, S.9
  • 46
    • 70350674207 scopus 로고    scopus 로고
    • Increased sister chromatid cohesion and DNA damage response factor localization at an enzyme-induced DNA double-strand break in vertebrate cells
    • Dodson H., Morrison C.G. Increased sister chromatid cohesion and DNA damage response factor localization at an enzyme-induced DNA double-strand break in vertebrate cells. Nucleic Acids Res. 2009, 37:6054-6063.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 6054-6063
    • Dodson, H.1    Morrison, C.G.2
  • 47
    • 0033569684 scopus 로고    scopus 로고
    • XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
    • Pierce A.J., Johnson R.D., Thompson L.H., Jasin M. XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev. 1999, 13:2633-2638.
    • (1999) Genes Dev. , vol.13 , pp. 2633-2638
    • Pierce, A.J.1    Johnson, R.D.2    Thompson, L.H.3    Jasin, M.4
  • 48
    • 0030271885 scopus 로고    scopus 로고
    • A method for isolation and purification of specific antibodies to a protein fused to the GST
    • Bar-Peled M., Raikhel N.V. A method for isolation and purification of specific antibodies to a protein fused to the GST. Anal. Biochem. 1996, 241:140-142.
    • (1996) Anal. Biochem. , vol.241 , pp. 140-142
    • Bar-Peled, M.1    Raikhel, N.V.2
  • 49
    • 0028109863 scopus 로고
    • ScII: an abundant chromosome scaffold protein is a member of a family of putative ATPases with an unusual predicted tertiary structure
    • Saitoh N., Goldberg I.G., Wood E.R., Earnshaw W.C. ScII: an abundant chromosome scaffold protein is a member of a family of putative ATPases with an unusual predicted tertiary structure. J. Cell Biol. 1994, 127:303-318.
    • (1994) J. Cell Biol. , vol.127 , pp. 303-318
    • Saitoh, N.1    Goldberg, I.G.2    Wood, E.R.3    Earnshaw, W.C.4
  • 51
    • 34447549077 scopus 로고    scopus 로고
    • Postreplicative formation of cohesion is required for repair and induced by a single DNA break
    • Strom L., Karlsson C., Lindroos H.B., Wedahl S., Katou Y., Shirahige K., Sjogren C. Postreplicative formation of cohesion is required for repair and induced by a single DNA break. Science 2007, 317:242-245.
    • (2007) Science , vol.317 , pp. 242-245
    • Strom, L.1    Karlsson, C.2    Lindroos, H.B.3    Wedahl, S.4    Katou, Y.5    Shirahige, K.6    Sjogren, C.7
  • 52
    • 10944232673 scopus 로고    scopus 로고
    • Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair
    • Strom L., Lindroos H.B., Shirahige K., Sjogren C. Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair. Mol. Cell 2004, 16:1003-1015.
    • (2004) Mol. Cell , vol.16 , pp. 1003-1015
    • Strom, L.1    Lindroos, H.B.2    Shirahige, K.3    Sjogren, C.4
  • 53
    • 34447536708 scopus 로고    scopus 로고
    • DNA double-strand breaks trigger genome-wide sister-chromatid cohesion through Eco1 (Ctf7)
    • Unal E., Heidinger-Pauli J.M., Koshland D. DNA double-strand breaks trigger genome-wide sister-chromatid cohesion through Eco1 (Ctf7). Science 2007, 317:245-248.
    • (2007) Science , vol.317 , pp. 245-248
    • Unal, E.1    Heidinger-Pauli, J.M.2    Koshland, D.3
  • 55
    • 69949088463 scopus 로고    scopus 로고
    • Structural and functional insights into the roles of the Mms21 subunit of the Smc5/6 complex
    • Duan X., Sarangi P., Liu X., Rangi G.K., Zhao X., Ye H. Structural and functional insights into the roles of the Mms21 subunit of the Smc5/6 complex. Mol. Cell 2009, 35:657-668.
    • (2009) Mol. Cell , vol.35 , pp. 657-668
    • Duan, X.1    Sarangi, P.2    Liu, X.3    Rangi, G.K.4    Zhao, X.5    Ye, H.6
  • 56
    • 33646194957 scopus 로고    scopus 로고
    • Smc5p promotes faithful chromosome transmission and DNA repair in Saccharomyces cerevisiae
    • Cost G.J., Cozzarelli N.R. Smc5p promotes faithful chromosome transmission and DNA repair in Saccharomyces cerevisiae. Genetics 2006, 172:2185-2200.
    • (2006) Genetics , vol.172 , pp. 2185-2200
    • Cost, G.J.1    Cozzarelli, N.R.2


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