Spontaneous formation of IpaB ion channels in host cell membranes reveals how Shigella induces pyroptosis in macrophages

Cell Death and Disease

Volumn 3, Issue 9, 2012, Pages

  SenerovicL , ^a,b   Tsunoda, S P ^c   GoosmannC , ^a   Brinkmann, V ^a   Zychlinsky, A ^a   Meissner, F ^a,d   Kolbe, M ^a  

^a MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

^b UNIVERSITY OF BELGRADE   (Serbia)

^c Experimental Biophysics Institute of Biology   (Germany)

^d MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

Endocytosis; Ion channel; IpaB; Macrophages; Pyroptosis; Shigella flexneri

Indexed keywords

BACTERIAL ANTIGEN; CATION CHANNEL; INTERLEUKIN 1BETA CONVERTING ENZYME; INVASION PLASMID ANTIGEN B; POTASSIUM; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ARTICLE; BACTERIAL VIRULENCE; CELL DEATH; CELL MEMBRANE; CELL VACUOLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTERNALIZATION; MACROPHAGE; MEMBRANE DAMAGE; NONHUMAN; OLIGOMERIZATION; PHAGOSOME; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PYROPTOSIS; SHIGELLA FLEXNERI;

ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; CASPASE 1; CELL MEMBRANE; ENDOSOMES; HEK293 CELLS; HELA CELLS; HUMANS; ION CHANNELS; LYSOSOMES; MACROPHAGES; OOCYTES; PATCH-CLAMP TECHNIQUES; PHAGOSOMES; POTASSIUM; RECOMBINANT PROTEINS; SHIGELLA FLEXNERI; XENOPUS LAEVIS;

NEGIBACTERIA; SHIGELLA; SHIGELLA FLEXNERI;

EID: 84867194710     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.124     Document Type: Article

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