Global burden of Shigella infections: Implications for vaccine development and implementation of control strategies

Bulletin of the World Health Organization

Volumn 77, Issue 8, 1999, Pages 651-666

  Kotloff, K L ^a   Winickoff, J P ^b   Ivanoff, B ^c   Clemens, J D ^d   Swerdlow, D L ^e   Sansonetti, P J ^f   Adak, G K ^g   Levine, M M ^h  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c WORLD HEALTH ORGANIZATION   (Switzerland)

^d EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^e NATL CENTER FOR INFECTIOUS DISEASES   (United States)

^f INSTITUT PASTEUR   (France)

^g PUBLIC HEALTH ENGLAND   (United Kingdom)

^h University of Maryland School of Medicine Center for Vaccine Development   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SHIGELLA VACCINE;

DISEASE CONTROL; IMPLEMENTATION PROCESS; INFECTIOUS DISEASE; VACCINATION;

ARTICLE; BACTERIAL VIRULENCE; BACTERIUM IDENTIFICATION; HUMAN; INCIDENCE; INFECTION CONTROL; MAJOR CLINICAL STUDY; SHIGELLA; SHIGELLA DYSENTERIAE; SHIGELLA FLEXNERI; SHIGELLA SONNEI; SHIGELLOSIS; TREATMENT PLANNING; VACCINE PRODUCTION;

BACTERIAL AND FUNGAL DISEASES; DEMOGRAPHIC FACTORS; DISEASES; INFECTIONS; LITERATURE REVIEW; MORBIDITY; MORTALITY; POPULATION; POPULATION DYNAMICS; WORLD;

ADOLESCENT; ADULT; AGE FACTORS; AUSTRALIA; CHILD; CHILD DAY CARE CENTERS; CHILD, PRESCHOOL; DEVELOPED COUNTRIES; DEVELOPING COUNTRIES; DYSENTERY, BACILLARY; FRANCE; GREAT BRITAIN; HUMANS; INCIDENCE; INFANT; INFANT, NEWBORN; ISRAEL; JEWS; MIDDLE AGED; RISK FACTORS; SHIGELLA BOYDII; SHIGELLA DYSENTERIAE; SHIGELLA FLEXNERI; SHIGELLA SONNEI; TRAVEL; UNITED STATES;

EID: 0032879806     PISSN: 00429686     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (119)

1. Rahaman MM et al. Diarrhoeal mortality in two Bangladesh villages with and without community-based oral rehydration therapy. Lancet, 1979, 2: 809-812.
2. Heymann DL et al. Oral rehydration therapy in Malawi: impact on the severity of disease and on hospital admissions, treatment practices, and recurrent costs. Bulletin of the World Health Organization, 1990, 68: 193-197.
3. Chowdhury HR et al. Is acute watery diarrhoea an important cause of morbidity and mortality among rural Bangladesh children? Transactions of the Royal Society of Tropical Medicine and Hygiene, 1991, 85: 128-130.
4. el-Rafie M et al. Effect of diarrhoeal disease control on infant and childhood mortality in Egypt. Report from the National Control of Diarrheal Diseases Project. Lancet, 1990, 335: 334-338.
5. Khan MU et al. Fourteen years of shigellosis in Dhaka an epidemiological analysis. International journal of epidemiology, 1985, 14: 607-613.
6. Bennish ML, Wojtyniak BJ. Mortality due to shigellosis: community and hospital data. Reviews of infectious diseases, 1991, 13 (suppl. 4): S245-S251.
7. Sack RB et al. Antimicrobial resistance in organisms causing diarrheal disease. Clinical infectious diseases, 1997, 24 (suppl. 1): S102-S105.
8. Gangarosa EJ et al. Epidemic Shiga bacillus dysentery in Central America. II. Epidemiologic studies in 1969. Journal of infectious diseases, 1970, 122: 181-190.
9. Rahaman MM et al. An outbreak of dysentery caused by Shigella dysenteriaetype 1 on a coral island in the Bay of Bengal. Journal of infectious diseases, 1975, 132: 15-19.
10. Ries AA et al. Epidemic Shigella dysenteriae type 1 in Burundi: pan-resistance and implications for prevention. Journal of infectious diseases, 1994, 169: 1035-1041.
11. Green MS et al. Four decades of shigellosis in Israel: epidemiology of a growing public health problem. Reviews of infectious diseases, 1991, 13: 248-253.
12. Wharton M et al. A large outbreak of antibiotic-resistant shigellosis at a mass gathering. Journal of infectious diseases, 1990, 162: 1324-1328.
13. Pickering LK et al. Diarrhea caused by Shigella, rotavirus, and Giardia in daycare centers: prospective tudy. Journal of pediatrics, 1981, 99: 51-56.
14. Mahoney FJ et al. Evaluation of an intervention program for the control of an outbreak of shigellosis among institutionalized persons. Journal of infectious diseases, 1993, 168: 1177-1180.
15. Sharp TW et al. Diarrheal disease among military personnel during Operation Restore Hope, Somalia, 1992-1993. American journal of tropical medicine and hygiene, 1995, 52: 188-193.
16. Colebunders R et al. Persistent diarrhea, strongly associated with HIV infection in Kinshasa, Zaire. American journal of gastroenterology, 1987, 82: 859-864.
17. van Oosterhout JJ, van der Hoek W. Infection with HIV, a risk factor for epidemic dysentery? A case-control study from Zambia [letter]. AIDS, 1994, 8: 1512-1513.
18. Clerinx J et al. Chronic diarrhea among adults in Kigali, Rwanda: association with bacterial enteropathogens, rectocolonic inflammation, and human immunodeficiency virus infection. Clinical infectious diseases, 1995, 21: 1282-1284.
19. Laughon BE et al. Prevalence of enteric pathogens in homosexual men with and without acquired immunodeficiency syndrome. Gastroenterology, 1988, 94: 984-993.
20. Quinn TC et al. The polymicrobial origin of intestinal infections in homosexual men. New England journal of medicine, 1983, 309: 576-582.
21. Angulo FJ, Swerdlow DL. Bacterial enteric infections in persons infected with human immunodeficiency virus. Clinical infectious diseases, 1995, 21 (Suppl. 1): 584-593.
22. Dougherty MJ et al. Evaluation of an extended blood culture protocol to isolate fastidious organisms from patients with AIDS. Journal of clinical microbiology, 1996, 34: 2444-2447.
23. Kristjansson M, Viner B, Maslow JN. Polymicrobial and recurrent bacteremia with Shigella in a patient with AIDS. Scandinavian journal of infectious diseases, 1994, 26: 411-416.
24. Huebner J et al. Shigellemia in AIDS patients: case report and review of the literature. Infection, 1993, 21: 122-124.
25. Batchelor BI, Kimari JN, Brindle RJ. Microbiology of HIV associated bacteraemia and diarrhoea in adults from Nairobi, Kenya. Epidemiology and infection, 1996, 117: 139-144.
26. Coster TS et al. Vaccination against shigellosis with attenuated Shigella flexneri 2a strain SC602. Infection and immunity, 1999, 67: 3437-3443.
27. Noriega FR et al. Engineered guaB-A virG Shigella flexneri 2a strain CVD 1205: construction, safety, immunogenicity, and potential efficacy as a mucosal vaccine. Infection and immunity, 1996, 64: 3055-3061.
28. Cohen D et al. Double-blind vaccine-controlled randomised efficacy trial of an investigational Shigella sonnei conjugate vaccine in young adults. Lancet, 1997, 349: 155-159.
29. New strategies for accelerating Shigella vaccine development. Weekly epidemiological record, 1997, 72: 73-80.
30. Levine MM, Levine OS. Influence of disease burden, public perception, and other factors on new vaccine development, implementation, and continued use. Lancet, 1997, 350: 1386-1392.
31. United Nations Children's Fund. The state of the world's children 1996. New York, Oxford University Press; 1996.
32. Ferreccio C et al. Epidemiologic patterns of acute diarrhea and endemic Shigella infections in a poor periurban setting in Santiago, Chile. American journal of epidemiology, 1991, 134: 614-627.
33. Murray PR, Baron EJ, Pfaller MA et al. eds. Manual of clinical microbiology, 6th ed. Washington, DC, ASM Press, 1998.
34. Ramiro Cruz J et al. Infection, diarrhea, and dysentery caused by Shigella species and Campylobacter jejuni among Guatemalan rural children. Pediatric infectious disease journal, 1994, 13: 216-223.
35. The sex and age distribution of the world populations. The 1994 revision. New York, United Nations, 1994.
36. Bern C et al. The magnitude of the global problem of diarrhoeal disease: a ten-year update. Bulletin of the World Health Organization, 1992, 70: 705-714.
37. Cravioto A et al. Risk of diarrhea during the first year of life associated with initial and subsequent colonization by specific enteropathogens. American journal of epidemiology, 1990, 131: 886-904.
38. Black RE et al. Incidence and etiology of infantile diarrhea and major routes of transmission in Huascar, Peru. American journal of epidemiology, 1989, 129: 785-799.
39. Cravioto A et al. Prospective study of diarrhoeal disease in a cohort of rural Mexican children: incidence and isolated pathogens during the first two years of life. Epidemiology and infection, 1988, 101: 123-134.
40. Punyaratabandhu P et al. Childhood diarrhoea in a low-income urban community in Bangkok: incidence, clinical features, and child caretaker's behaviours. Journal of diarrhoeal diseases research, 1991, 9: 244-249.
41. Zaki AM et al. The detection of enteropathogens in acute diarrhea in a family cohort population in rural Egypt. American journal of tropical medicine and hygiene, 1986, 35: 1013-1022.
42. Baqui AH et al. Surveillance of patients attending a rural diarrhoea treatment centre in Bangladesh. Tropical and geographical medicine, 1991, 43: 17-22.
43. Osisanya JO et al. Acute diarrhoeal disease in Nigeria: detection of enteropathogens in a rural sub-Saharan population. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, 82: 773-777.
44. Stoll B et al. Epidemiologic and clinical features of patients with Shigella who attended a diarrheal disease hospital in Bangladesh. Journal of infectious diseases, 1982, 146: 177-199.
45. Gomes TA et al. Enteropathogens associated with acute diarrheal disease in urban infants in Sao Paulo, Brazil. Journal of infectious diseases, 1991, 164: 331-337.
46. Hossain MA, Albert MJ, Hasan KZ. Epidemiology of shigellosis in Teknaf, a coastal area of Bangladesh: a 10-year survey. Epidemiology and infection, 1990, 105: 41-49.
47. Casalino M et al. A two-year study of enteric infections associated with diarrhoeal diseases in children in urban Somalia. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, 82: 637-641.
48. Dutta P et al. Shigellosis in children: a prospective hospital based study. Indian pediatrics, 1992, 29: 1125-1130.
49. Adkins HJ et al. Two-year survey of etiologic agents of diarrheal disease at San Lazaro Hospital, Manila, Republic of the Philippines. Journal of clinical microbiology, 1987, 25: 1143-1147.
50. Katouli M et al. Aetiological studies of diarrhoeal diseases in infants and young children in Iran. Journal of tropical medicine and hygiene, 1990, 93: 22-27.
51. Black RE et al. Longitudinal studies of infectious diseases and physical growth in rural Bangladesh. II. Incidence of diarrhea and association with known pathogens. American journal of epidemiology, 1982, 115: 315-324.
52. Chen KC et al. The epidemiology of diarrhoeal diseases in southeastern China. Journal of diarrhoeal diseases research, 1991, 9: 94-99.
53. Begue RE et al. Diarrheal disease in Peru after the introduction of cholera. American journal of tropical medicine and hygiene, 1994, 51: 585-589.
54. Institute of Medicine. New vaccine development: establishing priorities. II. Diseases of importance in developing countries. Washington, DC, National Academy Press, 1986: Appendix D.
55. Foodborne and Diarrheal Diseases Branch. Shigella surveillance: annual tabulation summaries, 1993-1995 and 1996. Atlanta, Georgia: US Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Center for Infectious Diseases, Division of Bacterial and Mycotic Diseases, Foodborne and Diarrheal Diseases Branch, 1996 and 1997, respectively.
56. Ostroi P, Anis E, Green MS. Shigellosis in Israel - update 1995. Public health reviews, 1996, 24: 213-225.
57. Eichner ER, Gangarosa EJ, Goldsby JB. The current status of shigellosis in the United States. American journal of public health, 1968, 58: 753-763.
58. Greenwood BM et al. Deaths in infancy and early childhood in a well-vaccinated, rural, West African population. Annals of tropical paediatrics, 1987, 7: 91-99.
59. Stanton B et al. Follow-up of children discharged from hospital after treatment for diarrhoea in urban Bangladesh. Tropical and geographical medicine, 1986, 38: 113-118.
60. Bennish ML et al. Death in shigellosis: incidence and risk factors in hospitalized patients. Journal of infectious diseases, 1990, 161: 500-506.
61. Islam SS, Shahid NS. Morbidity and mortality in a diarrhoeal diseases hospital in Bangladesh. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1986, 80: 748-752.
62. Tauxe RV et al. Antimicrobial resistance of Shigella isolates in the USA: the importance of international travelers. Journal of infectious diseases, 1990, 162: 1107-1111.
63. Moore PS et al. Mortality rates in displaced and resident populations of central Somalia during 1992 famine. Lancet, 1993, 341: 935-938.
64. Yip R, Sharp TW. Acute malnutrition and high childhood mortality related to diarrhea. Lessons from the 1991 Kurdish refugee crisis. Journal of the American Medical Association, 1993, 270: 587-590.
65. Centers for Disease Control and Prevention. Health status of displaced persons following Civil War - Burundi, December 1993-January 1994. Morbidity and mortality weekly report, 1994, 43: 701-703.
66. Goma Epidemiology Group. Public health impact of Rwandan refugee crisis: what happened in Goma, Zaire, in July, 1994? Lancet, 1995, 345: 339-344.
67. Marfin AA et al. Infectious disease surveillance during emergency relief to Bhutanese refugees in Nepal. Journal of the American Medical Association, 1994, 272: 377-381.
68. Intercountry meeting on dysentery in the African Region, Harare, 9-12 October 1995. Brazaville, WHO Regional Office for Africa, 1995: 1-77.
69. Black RE. Epidemiology of travelers' diarrhea and relative importance cf various pathogens. Reviews of infectious diseases, 1990, 12 (Suppl. 1): S73-S79.
70. Heikkila E et al. Increase of trimethoprim resistance among Shigella species, 1975-1988: analysis of resistance mechanisms. Journal of infectious diseases, 1990, 161: 1242-1248.
71. Ueda Y et al. Bacteriological studies of traveler's diarrhoea. 5) Analysis of enteropathogenic bacteria at Osaka Airport Quarantine Station from January 1992 through September 3rd, 1994. Kansenshogaku Zasshi, 1996, 70: 29-41.
72. Felsen J. Bacillary dysentery, colitis and enteritis. Philadelphia, W.B. Saunders Co., 1945: 1.
73. Hyams KC et al. Diarrheal disease during Operation Desert Shield. New England journal of medicine, 1991, 325: 1423-1428.
74. Thomas ME, Tillett HE. Sonne dysentery in day schools and nurseries: an eighteen-year study in Edmonton. Journal of hygiene, 1973, 71: 593-602.
75. Thomas ME et al. Recurrent gastroenteritis in a preparatory school caused by Shigella sonnei and another agent. Lancet, 1974, 1: 978-981.
76. Vagn-Hansen L, Justesen T. Shigella sonnei: an epidemic in a day-care institution. Ugeskr Laeger, 1991, 153: 3001-3003.
77. Cain VS. Child care and child health: use of population surveys. Pediatrics, 1994, 94: 1096-1098.
78. West J, Wright D, Germino Hausken E. Childcare and early education program participation of infants, toddlers, and preschoclers. Statistics in brief(NCES 95-824). Washington, DC, US Depatment of Education, Office of Educational Research and Improvement, National Center for Education Statistics, 1995.
79. Mohle-Boetani JC et al. Communitywide shigellosis: control of an outbreak and risk factors in child day-care centers. American journal of public health, 1995, 85: 812-816.
80. Bartlett AV et al. Diarrheal illness among infants and toddlers in day care centers. I. Epidemiology and pathogens. Journal of pediatrics, 1985, 107: 495-502.
81. Pickering LK. Bacterial and parasitic enteropathogens in day care. Seminars in pediatric infectious diseases, 1990, 1:263-269.
82. Weissman JB et al. Shigellosis in daycare centers. Lancet, 1975, 1: 88-90.
83. Murray CJ, Lopez AD. Mortality by cause for eight regions of the world: Global Burden of Disease Study. Lancet, 1997, 349: 1269-1276.
84. Murray CJ, Lopez AD. Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. Lancet, 1997, 349: 1436-1442.
85. Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause, 1990-2020: Global Burden of Disease Study. Lancet, 1997, 349: 1498-1504.
86. Monto AS, Koopman JS. The Tecumseh Study. Xl. Occurrence of acute enteric illness in the community. American journal of epidemiology, 1980, 112: 323-333.
87. Hodges RG et al. A study of illness in a group of Cleveland families. XI. The occurrence of gastrointestinal symptoms. American journal of hygiene, 1956, 64: 349-356.
88. Reller LB et al. Epidemic shiga-bacillus dysentery in Central America. Evolution of the outbreak in El Salvador, 1969-70. American journal of tropical medicine and hygiene, 1971, 20: 934-940.
89. Han AM, Aye T, Hlaing T. An outbreak of dysentery due to Shigella dysenteriae type 1 in Rangoon, Burma. Journal of diarrhoeal diseases research, 1987, 5: 30-35.
90. Mel DM, Terzin AL, Vuksic L. Studies on vaccination against bacillary dysentery. 3. Effective oral immunization against Shigella flexneri 2a in a field trial. Bulletin of the World Health Organization, 1965, 32: 647-655.
91. Mel DM et al. Studies on vaccination against bacillary dysentery. 4. Oral immunization with live monotypic and combined vaccines. Bulletin of the World Health Organization, 1968, 39: 375-380.
92. DuPont HL et al. Immunity in shigellosis. II. Protection induced by oral live vaccine or primary infection. Journal of infectious diseases, 1972, 125: 12-16.
93. Herrington DA et al. Studies in volunteers to evaluate candidate Shigella vaccines: further experience with a bivalent Salmonella typhi-Shigella sonneivaccine and protection conferred by previous Shigella sonnei disease. Vaccine, 1990, 8: 353-357.
94. Kotloff KL et al. A modified Shigella volunteer challenge model in which the inoculum is administered with bicarbonate buffer: clinical experience and implications for Shigella infectivity. Vaccine, 1995, 13: 1488-1494.
95. Formal SB et al. Effect of prior infection with virulent Shigella flexneri 2a on the resistance of monkeys to subseguent infection with Shigella sonnei. Journal of infectious diseases, 1991, 164: 533-537.
96. Van de Verg LL et al. Cross-reactivity of Shigella flexneri serotype 2a O antigen antibodies following immunization or infection. Vaccine, 1996, 14: 1062-1068.
97. Noriega FR et al. Strategy for cross-protection among Shigella flexneri serotypes. Infection and immunity, 1999, 67: 782-788.
98. Huilan S et al. Etiology of acute diarrhoea among children in developing countries: a multicentre study in five countries. Bulletin of the World Health Organization, 1991, 69: 549-555.
99. al-Freihi H et al. The microbiology of acute diarrhoea' disease in the eastern province of Saudi Arabia. East African medical journal, 1993, 70: 267-269.
100. Echeverria P et al. A comparative study of enterotoxigenic Escherichia coli, Shigella, Aeromonas, and Vibrio as, etiologies of diarrhea in northeastern Thailand. American journal of tropical medicine and hygiene, 1985, 34: 547-554.
101. Echeverria P et al. A longitudinal study of the prevalence of bacterial enteric pathogens among adults with diarrhea in Bangkok, Thailand. Diagnostic microbiology and infectious disease, 1983, 1: 193-204.
102. Panigrahi D et al. Incidence of shigellosis and multi-drug resistant Shigellae: a 10-year study. Journal of tropical medicine and hygiene, 1987, 90: 25-29.
103. Leano FT, Saniel MC, Monzon OT. Prevalent serogroups and antimicrobial susceptibility of Shigella strains in Metro Manila, 1982-1988. Southeast Asian journal of tropical medicine and public health, 1990, 21: 207-213.
104. Dutta P et al. Clinical and bacteriological profiles of shigellosis in Calcutta before and after an epidemic (1984-87). Indian journal of medical research, 1989, 89: 132-137.
105. Thisyakorn US, Rienprayoon S. Shigellosis in Thai children: epidemiologic, clinical and laboratory features. Pediatric infectious disease journal, 1992, 11: 213-215.
106. Srison D, Pornpatkul V. Shigellosis in Thai children: experience from a rural hospital 1985-1993. Southeast Asian journal of tropical medicine and public health, 1995, 26: 347-349.
107. Lim YS, Tay L. Serotype distribution and antimicrobial resistance of Shigella isolates in Singapore. Journal of diarrhoeal disease research, 1991, 9: 328-331.
108. Eko FO, Utsalo SJ. Antimicrobial resistance trends of shigellae isolates from Calabar, Nigeria. Journal of tropical medicine and hygiene, 1991, 94: 407-410.
109. Sethi SK, Khuffash F. Bacterial and viral causes of acute diarrhoea in children in Kuwait. Journal of diarrhoeal disease research, 1989, 7: 85-88.
110. Kagalwalla AF et al. Childhood shigellosis in Saudi Arabia. Pediatric infectious disease journal, 1992, 11: 215-219.
111. al-Eissa Y et al. The relative importance of Shigella in the aetiology of childhood gastroenteritis in Saudi Arabia. Scandinavian journal of infectious diseases, 1992, 24: 347-351.
112. Akman M. Shigella types found in Ankara: an analysis of 332 isolated strains. Turkish journal of pediatrics, 1965, 7: 154-160.
113. al-Sallami S. Shigellae and Vibrionaceae species as a cause of diarrhoea among children in Aden. Journal of the Egyptian Public Health Association, 1989, 64: 381-389.
114. Jegathesan M. Serotype prevalence and antibiotic susceptibility of Shigella strains isolated in Malaysia during 1980 and 1981. Journal of diarrhoeal diseases research, 1984, 2: 102-104.
115. Velasco AC et al. Three-year prospective study of intestinal pathogens in Madrid, Spain. Journal of clinical microbiology, 1984, 20: 290-292.
116. Finkelman Y et al. Epidemiology of Shigella infections in two ethnic groups in a geographic region in southern Israel. European journal of clinical microbiology and infectious diseases, 1994, 13: 367-373.
117. Admoni O et al. Epidemiological, clinical and microbiological features of shigellosis among hospitalized children in northern Israel. Scandinavian journal of infectious diseases, 1995, 27: 139-144.
118. Ashkenazi S et al. Recent trends in the epidemiology of Shigella species in Israel. Clinical infectious diseases, 1993, 17: 897-899.
119. Rudnai O et al. Salmonella and Shigella surveillance in Hungary, 1972-1976. II. Shigella surveillance. Acta microbiologica hungarica, 1981, 28: 53-65.