A systems biology approach to deciphering the etiology of steatosis employing patient-derived dermal fibroblasts and iPS cells

Frontiers in Physiology

Volumn 3 SEP, Issue , 2012, Pages

  Jozefczuk, Justyna ^a   Kashofer, Karl ^b   Ummanni, Ramesh ^c,k   Henjes, Frauke ^c   Rehman, Samrina ^d   Geenen, Suzanne ^d   Wruck, Wasco ^e   Regenbrecht, Christian ^e   Daskalaki, Andriani ^a   Wierling, Christoph ^a   Turano, Paola ^f   Bertini, Ivano ^f   Korf, Ulrike ^c   Zatloukal, Kurt ^b   Westerhoff, Hans V ^d,g,h   Lehrach, Hans ^a,i   Adjaye, James ^a,j  

^a MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^f UNIVERSITY OF FLORENCE   (Italy)

^g VU UNIVERSITY AMSTERDAM   (Netherlands)

^h UNIVERSITY OF AMSTERDAM   (Netherlands)

ⁱ Dahlem Centre for Genome Research and Medical Systems Biology   (Germany)

^j Department of Orthopedic Surgery   (Germany)

^k INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

more..

Author keywords

AKT mTOR signaling; Glutathione metabolism; Induced pluripotent stem cells; Lipid metabolism; Modeling; NAFLD; Sterol biosynthesis; Systems biology

Indexed keywords

EID: 84867188956     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2012.00339     Document Type: Article

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