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Volumn 77, Issue 13, 2012, Pages 1359-1365

Fat-reducing effects of dehydroepiandrosterone involve upregulation of ATGL and HSL expression, and stimulation of lipolysis in adipose tissue

Author keywords

ATGL; DHEA; HSL; PPAR ; Rat; White adipose tissue

Indexed keywords

ADIPOSE TRIGLYCERIDE LIPASE; CD36 ANTIGEN; ESTERASE; FATTY ACID; GLYCEROL; HORMONE SENSITIVE LIPASE; LEPTIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; PRASTERONE; UNCLASSIFIED DRUG;

EID: 84867049668     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2012.08.002     Document Type: Article
Times cited : (36)

References (44)
  • 1
    • 0026629845 scopus 로고
    • Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men
    • N. Orentreich, J.L. Brind, J.H. Vogelman, R. Andres, and H. Baldwin Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men J Clin Endocrinol Metab 75 1992 1002 1004
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 1002-1004
    • Orentreich, N.1    Brind, J.L.2    Vogelman, J.H.3    Andres, R.4    Baldwin, H.5
  • 2
    • 0030739131 scopus 로고    scopus 로고
    • Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging
    • DOI 10.1210/jc.82.8.2396
    • F. Labrie, A. Belanger, L. Cusan, J.L. Gomez, and B. Candas Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging J Clin Endocrinol Metab 82 1997 2396 2402 (Pubitemid 27337846)
    • (1997) Journal of Clinical Endocrinology and Metabolism , vol.82 , Issue.8 , pp. 2396-2402
    • Labrie, F.1    Belanger, A.2    Cusan, L.3    Gomez, J.-L.4    Candas, B.5
  • 3
    • 4344576898 scopus 로고    scopus 로고
    • Dehydroepiandrosterone, obesity and cardiovascular disease risk: A review of human studies
    • DOI 10.1530/eje.0.1510001
    • A. Tchernof, and F. Labrie Dehydroepiandrosterone, obesity and cardiovascular disease risk: a review of human studies Eur J Endocrinol 151 2004 1 14 (Pubitemid 39117360)
    • (2004) European Journal of Endocrinology , vol.151 , Issue.1 , pp. 1-14
    • Tchernof, A.1    Labrie, F.2
  • 4
    • 0242416723 scopus 로고    scopus 로고
    • DHEA protects against visceral obesity and muscle insulin resistance in rats fed a high-fat diet
    • P.A. Hansen, D.H. Han, L.A. Nolte, M. Chen, and J.O. Holloszy DHEA protects against visceral obesity and muscle insulin resistance in rats fed a high-fat diet Am J Physiol 273 1997 R1704 R1708
    • (1997) Am J Physiol , vol.273
    • Hansen, P.A.1    Han, D.H.2    Nolte, L.A.3    Chen, M.4    Holloszy, J.O.5
  • 5
    • 20444477160 scopus 로고    scopus 로고
    • Effect of DHEA on endocrine functions of adipose tissue, the involvement of PPARγ
    • DOI 10.1016/j.bcp.2005.04.022, PII S0006295205002509
    • J. Karbowska, and Z. Kochan Effect of DHEA on endocrine functions of adipose tissue, the involvement of PPARγ Biochem Pharmacol 70 2005 249 257 (Pubitemid 40814407)
    • (2005) Biochemical Pharmacology , vol.70 , Issue.2 , pp. 249-257
    • Karbowska, J.1    Kochan, Z.2
  • 6
    • 2342584138 scopus 로고    scopus 로고
    • Dehydroepiandrosterone up-regulates resistin gene expression in white adipose tissue
    • DOI 10.1016/j.mce.2003.12.012, PII S0303720703005586
    • Z. Kochan, and J. Karbowska Dehydroepiandrosterone up-regulates resistin gene expression in white adipose tissue Mol Cell Endocrinol 218 2004 57 64 (Pubitemid 38569927)
    • (2004) Molecular and Cellular Endocrinology , vol.218 , Issue.1-2 , pp. 57-64
    • Kochan, Z.1    Karbowska, J.2
  • 8
    • 0029001104 scopus 로고
    • Increased lipolysis to β-adrenergic stimulation after dehydroepiandrosterone treatment in rats
    • A.R. Tagliaferro, A.M. Ronan, J. Payne, L.D. Meeker, and S. Tse Increased lipolysis to β-adrenergic stimulation after dehydroepiandrosterone treatment in rats Am J Physiol 268 1995 R1374 R13780
    • (1995) Am J Physiol , vol.268
    • Tagliaferro, A.R.1    Ronan, A.M.2    Payne, J.3    Meeker, L.D.4    Tse, S.5
  • 9
    • 0023838538 scopus 로고
    • Dehydroepiandrosterone reduces serum low density lipoprotein levels and body fat but does not alter insulin sensitivity in normal men
    • J.E. Nestler, C.O. Barlascini, J.N. Clore, and W.G. Blackard Dehydroepiandrosterone reduces serum low density lipoprotein levels and body fat but does not alter insulin sensitivity in normal men J Clin Endocrinol Metab 66 1988 57 61 (Pubitemid 18027729)
    • (1988) Journal of Clinical Endocrinology and Metabolism , vol.66 , Issue.1 , pp. 57-61
    • Nestler, J.E.1    Barlascini, C.O.2    Clore, J.N.3    Blackard, W.G.4
  • 10
    • 0031719355 scopus 로고    scopus 로고
    • The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women
    • DOI 10.1046/j.1365-2265.1998.00507.x
    • A.J. Morales, R.H. Haubrich, J.Y. Hwang, H. Asakura, and S.S. Yen The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women Clin Endocrinol 49 1998 421 432 (Pubitemid 28475333)
    • (1998) Clinical Endocrinology , vol.49 , Issue.4 , pp. 421-432
    • Morales, A.J.1    Haubricht, R.H.2    Hwang, J.Y.3    Asakura, H.4    Yen, S.S.C.5
  • 11
    • 7744230247 scopus 로고    scopus 로고
    • Effect of DHEA on abdominal fat and insulin action in elderly women and men: A randomized controlled trial
    • DOI 10.1001/jama.292.18.2243
    • D.T. Villareal, and J.O. Holloszy Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial J Am Med Assoc 292 2004 2243 2248 (Pubitemid 39473162)
    • (2004) Journal of the American Medical Association , vol.292 , Issue.18 , pp. 2243-2248
    • Villareal, D.T.1    Holloszy, J.O.2
  • 12
    • 80053116974 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans
    • E.P. Weiss, D.T. Villareal, L. Fontana, D.H. Han, and J.O. Holloszy Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans Aging 3 2011 533 542
    • (2011) Aging , vol.3 , pp. 533-542
    • Weiss, E.P.1    Villareal, D.T.2    Fontana, L.3    Han, D.H.4    Holloszy, J.O.5
  • 13
    • 77949570155 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) treatment in vitro inhibits adipogenesis in human omental but not subcutaneous adipose tissue
    • S.P.L. Rice, L. Zhang, F. Grennan-Jones, N. Agarwal, M.D. Lewis, D.A. Rees, and M. Ludgate Dehydroepiandrosterone (DHEA) treatment in vitro inhibits adipogenesis in human omental but not subcutaneous adipose tissue Mol Cell Endocrinol 320 2010 51 57
    • (2010) Mol Cell Endocrinol , vol.320 , pp. 51-57
    • Rice, S.P.L.1    Zhang, L.2    Grennan-Jones, F.3    Agarwal, N.4    Lewis, M.D.5    Rees, D.A.6    Ludgate, M.7
  • 14
    • 0037418690 scopus 로고    scopus 로고
    • DHEA administration increases brown fat uncoupling protein 1 levels in obese OLETF rats
    • J.W. Ryu, M.S. Kim, C.H. Kim, K.H. Song, J.Y. Park, and J.D. Lee DHEA administration increases brown fat uncoupling protein 1 levels in obese OLETF rats Biochem Biophys Res Commun 303 2003 726 731
    • (2003) Biochem Biophys Res Commun , vol.303 , pp. 726-731
    • Ryu, J.W.1    Kim, M.S.2    Kim, C.H.3    Song, K.H.4    Park, J.Y.5    Lee, J.D.6
  • 16
    • 81155148223 scopus 로고    scopus 로고
    • Alternative mechanism for anti-obesity effect of dehydroepiandrosterone: Possible contribution of 11β-hydroxysteroid dehydrogenase type 1 inhibition in rodent adipose tissue
    • N. Tagawa, E. Minamitani, Y. Yamaguchi, and Y. Kobayashi Alternative mechanism for anti-obesity effect of dehydroepiandrosterone: possible contribution of 11β-hydroxysteroid dehydrogenase type 1 inhibition in rodent adipose tissue Steroids 76 2011 1546 1553
    • (2011) Steroids , vol.76 , pp. 1546-1553
    • Tagawa, N.1    Minamitani, E.2    Yamaguchi, Y.3    Kobayashi, Y.4
  • 17
    • 78650107057 scopus 로고    scopus 로고
    • Lipolysis - A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores
    • A. Lass, R. Zimmermann, M. Oberer, and R. Zechner Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores Prog Lipid Res 50 2011 14 27
    • (2011) Prog Lipid Res , vol.50 , pp. 14-27
    • Lass, A.1    Zimmermann, R.2    Oberer, M.3    Zechner, R.4
  • 21
    • 10344262633 scopus 로고    scopus 로고
    • 2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities
    • DOI 10.1074/jbc.M407841200
    • C.M. Jenkins, D.J. Mancuso, W. Yan, H.F. Sims, B. Gibson, and R.W. Gross Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities J Biol Chem 279 2004 48968 48975 (Pubitemid 39625778)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.47 , pp. 48968-48975
    • Jenkins, C.M.1    Mancuso, D.J.2    Yan, W.3    Sims, H.F.4    Gibson, B.5    Gross, R.W.6
  • 22
    • 8744297386 scopus 로고    scopus 로고
    • Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: Ectopic expression of desnutrin increases triglyceride hydrolysis
    • DOI 10.1074/jbc.M403855200
    • J.A. Villena, S. Roy, E. Sarkadi-Nagy, K.H. Kim, and H.S. Sul Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis J Biol Chem 279 2004 47066 47075 (Pubitemid 39518362)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.45 , pp. 47066-47075
    • Villena, J.A.1    Roy, S.2    Sarkadi-Nagy, E.3    Kim, K.-H.4    Hei, S.S.5
  • 23
    • 33646462136 scopus 로고    scopus 로고
    • Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
    • G. Haemmerle, A. Lass, R. Zimmermann, G. Gorkiewicz, C. Meyer, and J. Rozman Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase Science 312 2006 734 737
    • (2006) Science , vol.312 , pp. 734-737
    • Haemmerle, G.1    Lass, A.2    Zimmermann, R.3    Gorkiewicz, G.4    Meyer, C.5    Rozman, J.6
  • 25
    • 0033562350 scopus 로고    scopus 로고
    • Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro
    • DOI 10.1006/abio.1999.4085
    • J. Winer, C.K. Jung, I. Shackel, and P.M. Williams Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro Anal Biochem 270 1999 41 49 (Pubitemid 29230718)
    • (1999) Analytical Biochemistry , vol.270 , Issue.1 , pp. 41-49
    • Winer, J.1    Jung, C.K.S.2    Shackel, I.3    Williams, P.M.4
  • 26
    • 0034801882 scopus 로고    scopus 로고
    • Rat PPARs: Quantitative analysis in adult rat tissues and regulation in fasting and refeeding
    • DOI 10.1210/en.142.10.4195
    • P. Escher, O. Braissant, S. Basu-Modak, L. Michalik, W. Wahli, and B. Desvergne Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding Endocrinology 142 2001 4195 4202 (Pubitemid 32907045)
    • (2001) Endocrinology , vol.142 , Issue.10 , pp. 4195-4202
    • Escher, P.1    Braissant, O.2    Basu-Modak, S.3    Michalik, L.4    Wahli, W.5    Desvergne, B.6
  • 28
    • 33751508400 scopus 로고    scopus 로고
    • Identification of peroxisome-proliferator responsive element in the mouse HSL gene
    • DOI 10.1016/j.bbrc.2006.11.054, PII S0006291X06025253
    • H. Yajima, Y. Kobayashi, T. Kanaya, and Y. Horino Identification of peroxisome-proliferator responsive element in the mouse HSL gene Biochem Biophys Res Commun 352 2007 526 531 (Pubitemid 44838517)
    • (2007) Biochemical and Biophysical Research Communications , vol.352 , Issue.2 , pp. 526-531
    • Yajima, H.1    Kobayashi, Y.2    Kanaya, T.3    Horino, Y.4
  • 29
    • 33746547216 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor subtype- and cell-type-specific activation of genomic target genes upon adenoviral transgene delivery
    • DOI 10.1128/MCB.02266-05
    • R. Nielsen, L. Grontved, H.G. Stunnenberg, and S. Mandrup Peroxisome proliferator-activated receptor subtype- and cell-type-specific activation of genomic target genes upon adenoviral transgene delivery Mol Cell Biol 26 2006 5698 5714 (Pubitemid 44134327)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.15 , pp. 5698-5714
    • Nielsen, R.1    Grontved, L.2    Stunnenberg, H.G.3    Mandrup, S.4
  • 30
    • 37649006568 scopus 로고    scopus 로고
    • Role of DHEA-S on body fat distribution: Gender- and depot-specific stimulation of adipose tissue lipolysis
    • J.J. Hernandez-Morante, F. Perez-de-Heredia, J.A. Lujan, S. Zamora, and M. Garaulet Role of DHEA-S on body fat distribution: gender- and depot-specific stimulation of adipose tissue lipolysis Steroids 73 2008 209 215
    • (2008) Steroids , vol.73 , pp. 209-215
    • Hernandez-Morante, J.J.1    Perez-De-Heredia, F.2    Lujan, J.A.3    Zamora, S.4    Garaulet, M.5
  • 31
    • 57349118544 scopus 로고    scopus 로고
    • Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes
    • H. Miyoshi, J.W. Perfield 2nd, M.S. Obin, and A.S. Greenberg Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes J Cell Biochem 105 2008 1430 1436
    • (2008) J Cell Biochem , vol.105 , pp. 1430-1436
    • Miyoshi, H.1    Perfield II, J.W.2    Obin, M.S.3    Greenberg, A.S.4
  • 32
    • 33745849713 scopus 로고    scopus 로고
    • The adipose tissue triglyceride lipase ATGL/PNPLA2 is downregulated by insulin and TNF-α in 3T3-L1 adipocytes and is a target for transactivation by PPARγ
    • J.Y. Kim, K. Tillison, J.H. Lee, D.A. Rearick, and C.M. Smas The adipose tissue triglyceride lipase ATGL/PNPLA2 is downregulated by insulin and TNF-α in 3T3-L1 adipocytes and is a target for transactivation by PPARγ Am J Physiol Endocrinol Metab 291 2006 E115 E127
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Kim, J.Y.1    Tillison, K.2    Lee, J.H.3    Rearick, D.A.4    Smas, C.M.5
  • 34
    • 40849086443 scopus 로고    scopus 로고
    • Modulation of receptor phosphorylation contributes to activation of peroxisome proliferator activated receptor α by dehydroepiandrosterone and other peroxisome proliferators
    • DOI 10.1124/mol.107.036780
    • V. Tamasi, K.K. Miller, S.L. Ripp, E. Vila, T.E. Geoghagen, and R.A. Prough Modulation of receptor phosphorylation contributes to activation of peroxisome proliferator activated receptor α by dehydroepiandrosterone and other peroxisome proliferators Mol Pharmacol 73 2008 968 976 (Pubitemid 351397901)
    • (2008) Molecular Pharmacology , vol.73 , Issue.3 , pp. 968-976
    • Tamasi, V.1    Michael Miller, K.K.2    Ripp, S.L.3    Vila, E.4    Geoghagen, T.E.5    Prough, R.A.6
  • 35
    • 40149090943 scopus 로고    scopus 로고
    • Inhibition of vascular inflammation by dehydroepiandrosterone sulfate in human aortic endothelial cells: Roles of PPARα and NF-κB
    • R. Altman, D.D. Motton, R.S. Kota, and J.C. Rutledge Inhibition of vascular inflammation by dehydroepiandrosterone sulfate in human aortic endothelial cells: roles of PPARα and NF-κB Vascul Pharmacol 48 2008 76 84
    • (2008) Vascul Pharmacol , vol.48 , pp. 76-84
    • Altman, R.1    Motton, D.D.2    Kota, R.S.3    Rutledge, J.C.4
  • 36
    • 2642614548 scopus 로고    scopus 로고
    • Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vitro
    • DOI 10.1074/jbc.273.1.215
    • M.W. Anthonsen, L. Ronnstrand, C. Wernstedt, E. Degerman, and C. Holm Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vitro J Biol Chem 273 1998 215 221 (Pubitemid 28042196)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.1 , pp. 215-221
    • Anthonsen, M.W.1    Ronnstrand, L.2    Wernstedt, C.3    Degerman, E.4    Holm, C.5
  • 37
    • 33751395911 scopus 로고    scopus 로고
    • Redox reactions of dehydroepiandrosterone and its metabolites in differentiating 3T3-L1 adipocytes: A liquid chromatographic-mass spectrometric study
    • DOI 10.1016/j.abb.2006.09.023, PII S0003986106003729
    • A. Marwah, F.E. Gomez, P. Marwah, J.M. Ntambi, B.G. Fox, and H. Lardy Redox reactions of dehydroepiandrosterone and its metabolites in differentiating 3T3-L1 adipocytes: a liquid chromatographic-mass spectrometric study Arch Biochem Biophys 456 2006 1 7 (Pubitemid 44820023)
    • (2006) Archives of Biochemistry and Biophysics , vol.456 , Issue.1 , pp. 1-7
    • Marwah, A.1    Gomez, F.E.2    Marwah, P.3    Ntambi, J.M.4    Fox, B.G.5    Lardy, H.6
  • 38
    • 33646102678 scopus 로고    scopus 로고
    • Dehydroepiandrosterone and its metabolites: Differential effects on androgen receptor trafficking and transcriptional activity
    • Q. Mo, S.F. Lu, and N.G. Simon Dehydroepiandrosterone and its metabolites: differential effects on androgen receptor trafficking and transcriptional activity J Steroid Biochem Mol Biol 99 2006 50 58
    • (2006) J Steroid Biochem Mol Biol , vol.99 , pp. 50-58
    • Mo, Q.1    Lu, S.F.2    Simon, N.G.3
  • 39
    • 0036259046 scopus 로고    scopus 로고
    • The regulation of HSL and LPL expression by DHT and flutamide in human subcutaneous adipose tissue
    • DOI 10.1046/j.1463-1326.2002.00214.x
    • L.A. Anderson, P.G. McTernan, A.L. Harte, A.H. Barnett, and S. Kumar The regulation of HSL and LPL expression by DHT and flutamide in human subcutaneous adipose tissue Diabetes Obes Metab 4 2002 209 213 (Pubitemid 34567678)
    • (2002) Diabetes, Obesity and Metabolism , vol.4 , Issue.3 , pp. 209-213
    • Anderson, L.A.1    McTernan, P.G.2    Harte, A.L.3    Barnett, A.H.4    Kumar, S.5
  • 40
    • 34250623941 scopus 로고    scopus 로고
    • Transcriptomic characterization of the long-term dihydrotestosterone effects in adipose tissue
    • C. Bolduc, M. Yoshioka, and J. St-Amand Transcriptomic characterization of the long-term dihydrotestosterone effects in adipose tissue Obesity 15 2007 1107 1132 (Pubitemid 46932466)
    • (2007) Obesity , vol.15 , Issue.5 , pp. 1107-1132
    • Bolduc, C.1    Yoshioka, M.2    St-Amand, J.3
  • 41
    • 33747465130 scopus 로고    scopus 로고
    • A role of PPAR-γ in androstenediol-mediated salutary effects on cardiac function following trauma-hemorrhage
    • DOI 10.1097/01.sla.0000217709.00863.82, PII 0000065820060700000018
    • T. Shimizu, L. Szalay, Y.C. Hsieh, T. Suzuki, M.A. Choudhry, K.I. Bland, and I.H. Chaudry A role of PPAR-γ in androstenediol-mediated salutary effects on cardiac function following trauma-hemorrhage Ann Surg 244 2006 131 138 (Pubitemid 44297457)
    • (2006) Annals of Surgery , vol.244 , Issue.1 , pp. 131-138
    • Shimizu, T.1    Szalay, L.2    Hsieh, Y.-C.3    Suzuki, T.4    Choudhry, M.A.5    Bland, K.I.6    Chaudry, I.H.7
  • 42
    • 24344480045 scopus 로고    scopus 로고
    • Salutary effects of androstenediol on hepatic function after trauma-hemorrhage are mediated via peroxisome proliferators-activated receptor gamma
    • DOI 10.1016/j.surg.2005.03.017, PII S0039606005001984
    • T. Shimizu, L. Szalay, Y.C. Hsieh, M.A. Choudhry, K.I. Bland, and I.H. Chaudry Salutary effects of androstenediol on hepatic function after trauma-hemorrhage are mediated via peroxisome proliferators-activated receptor gamma Surgery 138 2005 204 211 (Pubitemid 41253802)
    • (2005) Surgery , vol.138 , Issue.2 , pp. 204-211
    • Shimizu, T.1    Szalay, L.2    Hsieh, Y.-C.3    Choudhry, M.A.4    Bland, K.I.5    Chaudry, I.H.6
  • 43
    • 84860895270 scopus 로고    scopus 로고
    • Ablation of Pparg2 impairs lipolysis and reveals murine strain differences in lipolytic responses
    • S. Rodriguez-Cuenca, S. Carobbio, and A. Vidal-Puig Ablation of Pparg2 impairs lipolysis and reveals murine strain differences in lipolytic responses FASEB J 26 2012 1835 1844
    • (2012) FASEB J , vol.26 , pp. 1835-1844
    • Rodriguez-Cuenca, S.1    Carobbio, S.2    Vidal-Puig, A.3
  • 44
    • 0022977654 scopus 로고
    • Palmitate and glycerol kinetics during brief starvation in normal weight young adult and elderly subjects
    • S. Klein, V.R. Young, G.L. Blackburn, B.R. Bistrian, and R.R. Wolfe Palmitate and glycerol kinetics during brief starvation in normal weight young adult and elderly subjects J Clin Invest 78 1986 928 933 (Pubitemid 17177072)
    • (1986) Journal of Clinical Investigation , vol.78 , Issue.4 , pp. 928-933
    • Klein, S.1    Young, V.R.2    Blackburn, G.L.3


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