Effects of perfusion and dynamic loading on human neocartilage formation in alginate hydrogels

Tissue Engineering - Part A

Volumn 18, Issue 17-18, 2012, Pages 1784-1792

  Grogan, Shawn P ^a,b   Sovani, Sujata ^a   Pauli, Chantal ^a,b   Chen, Jianfen ^a   Hartmann, Andreas ^a   Colwell, Clifford W ^a   Lotz, Martin K ^a,b   D'Lima, Darryl D ^a,b  

^a SCRIPPS CLINIC   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGINATE; BIOCONVERSION; BIOMECHANICS; BODY FLUIDS; CELL CULTURE; DYNAMIC LOADS; ENZYME INHIBITION; GENE EXPRESSION; GLYCOPROTEINS; MECHANICAL PROPERTIES; NITRIC OXIDE; PROTEINS; TISSUE;

ALGINATE GEL; ALGINATE HYDROGELS; ARTICULAR CHONDROCYTES; BIOREACTOR SYSTEM; CARTILAGE EXTRACELLULAR MATRIXES; CATABOLIC PROCESS; CELL VIABILITY; COMPRESSIVE LOADING; DUAL-RESPONSE; DYNAMIC LOADINGS; EXPRESSION LEVELS; GENE EXPRESSION ANALYSIS; GLYCOSAMINOGLYCANS; HUMAN ARTICULAR CHONDROCYTES; IMMUNOSTAINING; INDUCIBLE NITRIC OXIDE SYNTHASE; LINK PROTEIN; MATRIX-METALLOPROTEINASE-3; MECHANICAL PROPERTY TESTING; MRNA EXPRESSION LEVEL; MRNA LEVEL; NEOCARTILAGE; OPTIMAL CONDITIONS; PERFUSION CULTURES; PROTEIN DEPOSITION; STATIC CULTURE; TISSUE REMODELING; TYPE II;

BIOREACTORS;

ALGINIC ACID; DNA; GLUCURONIC ACID; GLYCOSAMINOGLYCAN; HEXURONIC ACID;

ADOLESCENT; ADULT; ARTICLE; ARTICULAR CARTILAGE; BIOREACTOR; CARTILAGE CELL; CELL CULTURE; CELL SURVIVAL; CHONDROGENESIS; CYTOLOGY; DRUG EFFECT; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; HYDROGEL; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; PERFUSION; PHYSIOLOGY; WEIGHT BEARING;

ADOLESCENT; ADULT; ALGINATES; BIOREACTORS; CARTILAGE, ARTICULAR; CELL SURVIVAL; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; DNA; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GLUCURONIC ACID; GLYCOSAMINOGLYCANS; HEXURONIC ACIDS; HUMANS; HYDROGELS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PERFUSION; WEIGHT-BEARING; YOUNG ADULT;

EID: 84866997014     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2011.0506     Document Type: Article

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