Rho kinase-dependent CCL20 induced by dynamic compression of human chondrocytes

Arthritis and Rheumatism

Volumn 58, Issue 9, 2008, Pages 2735-2742

  Haudenschild, Dominik R ^a   Nguyen, Bao ^b   Chen, Jianfen ^a   D'Lima, Darryl D ^b   Lotz, Martin K ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b SCRIPPS CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; AGAROSE; F ACTIN; GUANOSINE TRIPHOSPHATE; HYDROXYFASUDIL; INDUCIBLE NITRIC OXIDE SYNTHASE; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; PHALLOIDIN; RHO KINASE; RHO KINASE INHIBITOR;

ACTIN FILAMENT; ADOLESCENT; ADULT; ARTICLE; ARTICULAR CARTILAGE; CELL CULTURE; CELL LYSATE; COMPRESSION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; FLUORESCENCE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MALE; MECHANICAL STIMULATION; MECHANOTRANSDUCTION; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN STRUCTURE; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ACTINS; ADOLESCENT; ADULT; CELL CULTURE TECHNIQUES; CELL SHAPE; CELLS, CULTURED; CHEMOKINE CCL20; CHONDROCYTES; CYTOSKELETON; FEMALE; GENE EXPRESSION; HUMANS; INTERLEUKIN-1BETA; MALE; MECHANOTRANSDUCTION, CELLULAR; MICROSCOPY, CONFOCAL; MIDDLE AGED; NITRIC OXIDE SYNTHASE TYPE II; OSTEOARTHRITIS; PHYSICAL STIMULATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHO-ASSOCIATED KINASES; RNA, MESSENGER; STRESS, MECHANICAL; TIME FACTORS;

EID: 51849111513     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.23797     Document Type: Article

References (50)

1. Salter DM, Millward-Sadler SJ, Nuki G, Wright MO. Integrin-interleukin-4 mechanotransduction pathways in human chondrocytes. Clin Orthop Relat Res 2001;391 Suppl:S49-60.
2. Benya PD, Padilla SR, Nimni ME. Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture. Cell 1978;15:1313-21.
3. Dessau W, Vertel BM, von der Mark H, von der Mark K. Extracellular matrix formation by chondrocytes in monolayer culture. J Cell Biol 1981;90:78-83.
4. Glowacki J, Trepman E, Folkman J. Cell shape and phenotypic expression in chondrocytes. Proc Soc Exp Biol Med 1983;172:93-8.
5. Wang G, Beier F. Rac1/Cdc42 and RhoA GTPases antagonistically regulate chondrocyte proliferation, hypertrophy, and apoptosis. J Bone Miner Res 2005;20:1022-31.
6. Kronenberg HM. Developmental regulation of the growth plate. Nature 2003;423:332-6.
7. Von der Mark K, Gauss V, von der Mark H, Muller P. Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture. Nature 1977;267:531-2.
8. Loty S, Forest N, Boulekbache H, Sautier JM. Cytochalasin D induces changes in cell shape and promotes in vitro chondrogenesis: a morphological study. Biol Cell 1995;83:149-61.
9. Benya PD, Brown PD, Padilla SR. Microfilament modification by dihydrocytochalasin B causes retinoic acid-modulated chondrocytes to reexpress the differentiated collagen phenotype without a change in shape. J Cell Biol 1988;106:161-70.
10. Mallein-Gerin F, Garrone R, van der Rest M. Proteoglycan and collagen synthesis are correlated with actin organization in dedifferentiating chondrocytes. Eur J Cell Biol 1991;56:364-73.
11. Revenu C, Athman R, Robine S, Louvard D. The co-workers of actin filaments: from cell structures to signals. Nat Rev Mol Cell Biol 2004;5:635-46.
12. Schmidt A, Hall MN. Signaling to the actin cytoskeleton [review]. Annu Rev Cell Dev Biol 1998;14:305-38.
13. Sims JR, Karp S, Ingber DE. Altering the cellular mechanical force balance results in integrated changes in cell, cytoskeletal and nuclear shape. J Cell Sci 1992;103:1215-22.
14. Heath JP, Holifield BF. Cell locomotion: new research tests old ideas on membrane and cytoskeletal flow. Cell Motil Cytoskeleton 1991;18:245-57.
15. Turner CE, Burridge K. Transmembrane molecular assemblies in cell-extracellular matrix interactions. Curr Opin Cell Biol 1991;3:849-53.
16. Janmey PA. The cytoskeleton and cell signaling: component localization and mechanical coupling [review]. Physiol Rev 1998;78:763-81.
17. Simon VR, Pon LA. Actin-based organelle movement. Experientia 1996;52:1117-22.
18. Riezman H, Munn A, Geli MI, Hicke L. Actin-, myosin- and ubiquitin-dependent endocytosis. Experientia 1996;52:1033-41.
19. Trickey WR, Vail TP, Guilak F. The role of the cytoskeleton in the viscoelastic properties of human articular chondrocytes. J Orthop Res 2004;22:131-9.
20. Wang N, Butler JP, Ingber DE. Mechanotransduction across the cell surface and through the cytoskeleton. Science 1993;260:1124-7.
21. Durrant LA, Archer CW, Benjamin M, Ralphs JR. Organisation of the chondrocyte cytoskeleton and its response to changing mechanical conditions in organ culture. J Anat 1999;194:343-53.
22. Wang N, Stamenovic D. Mechanics of vimentin intermediate filaments. J Muscle Res Cell Motil 2002;23:535-40.
23. Bishop AL, Hall A. Rho GTPases and their effector proteins. Biochem J 2000;348 Pt 2:241-55.
24. Aspenstrom P. Effectors for the Rho GTPases. Curr Opin Cell Biol 1999;11:95-102.
25. Aspenstrom P. The Rho GTPases have multiple effects on the actin cytoskeleton. Exp Cell Res 1999;246:20-5.
26. Van Aelst L, D'Souza-Schorey C. Rho GTPases and signaling networks. Genes Dev 1997;11:2295-322.
27. Woods A, Wang G, Beier F. RhoA/ROCK signaling regulates Sox9 expression and actin organization during chondrogenesis. J Biol Chem 2005;280:11626-34.
28. Woods A, Beier F. RhoA/ROCK signaling regulates chondrogenesis in a context-dependent manner. J Biol Chem 2006;281:13134-40.
29. Li YS, Haga JH, Chien S. Molecular basis of the effects of shear stress on vascular endothelial cells. J Biomech 2005;38:1949-71.
30. Wang J, Zohar R, McCulloch CA. Multiple roles of "-smooth muscle actin in mechanotransduction. Exp Cell Res 2006;312:205-14.
31. Matthews BD, Overby DR, Mannix R, Ingber DE. Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels. J Cell Sci 2006;119:508-18.
32. Tzima E. Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response. Circ Res 2006;98:176-85.
33. Haudenschild DR, McPherson JM, Tubo R, Binette F. Differential expression of multiple genes during articular chondrocyte redifferentiation. Anat Rec 2001;263:91-8.
34. Li Z, Trick HN. Rapid method for high-quality RNA isolation from seed endosperm containing high levels of starch. Biotechniques 2005;38:872, 874, 876.
35. -ΔΔCT method. Methods 2001;25:402-8.
36. Ridley AJ. Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends Cell Biol 2006;16:522-9.
37. Schwartz M. Rho signalling at a glance. J Cell Sci 2004;117:5457-8.
38. Riento K, Ridley AJ. ROCKs: multifunctional kinases in cell behaviour [review]. Nat Rev Mol Cell Biol 2003;4:446-56.
39. Matsui T, Akahoshi T, Namai R, Hashimoto A, Kurihara Y, Rana M, et al. Selective recruitment of CCR6-expressing cells by increased production of MIP-3αα in rheumatoid arthritis. Clin Exp Immunol 2001;125:155-61.
40. Maier R, Bilbe G, Rediske J, Lotz M. Inducible nitric oxide synthase from human articular chondrocytes: cDNA cloning and analysis of mRNA expression. Biochim Biophys Acta 1994;1208:145-50.
41. Haga JH, Li YS, Chien S. Molecular basis of the effects of mechanical stretch on vascular smooth muscle cells. J Biomech 2006. E-pub ahead of print.
42. Erickson GR, Northrup DL, Guilak F. Hypo-osmotic stress induces calcium-dependent actin reorganization in articular chondrocytes. Osteoarthritis Cartilage 2003;11:187-97.
43. Fortier LA, Deak MM, Semevolos SA, Cerione RA. Insulin-like growth factor-I diminishes the activation status and expression of the small GTPase Cdc42 in articular chondrocytes. J Orthop Res 2004;22:436-45.
44. Knight MM, Toyoda T, Lee DA, Bader DL. Mechanical compression and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose. J Biomech 2006;39:1547-51.
45. Wang G, Woods A, Agoston H, Ulici V, Glogauer M, Beier F. Genetic ablation of Rac1 in cartilage results in chondrodysplasia. Dev Biol 2007. E-pub ahead of print.
46. Langelier E, Suetterlin R, Hoemann CD, Aebi U, Buschmann MD. The chondrocyte cytoskeleton in mature articular cartilage: structure and distribution of actin, tubulin, and vimentin filaments. J Histochem Cytochem 2000;48:1307-20.
47. Idowu BD, Knight MM, Bader DL, Lee DA. Confocal analysis of cytoskeletal organisation within isolated chondrocyte sub-populations cultured in agarose. Histochem J 2000;32:165-74.
48. Sah RL, Kim YJ, Doong JY, Grodzinsky AJ, Plaas AH, Sandy JD. Biosynthetic response of cartilage explants to dynamic compression. J Orthop Res 1989;7:619-36.
49. Yamamoto T, Takeda K, Harada S, Nakata T, Azuma A, Sasaki S, et al. HMG-CoA reductase inhibitor enhances inducible nitric oxide synthase expression in rat vascular smooth muscle cells; involvement of the Rho/Rho kinase pathway. Atherosclerosis 2003;166:213-22.
50. Schutyser E, Struyf S, Van Damme J. The CC chemokine CCL20 and its receptor CCR6. Cytokine Growth Factor Rev 2003;14:409-26.