Luteinizing hormone/human chorionic gonadotropin-mediated activation of mTORC1 signaling is required for androgen synthesis by theca-interstitial cells

Molecular Endocrinology

Volumn 26, Issue 10, 2012, Pages 1732-1742

  Palaniappan, Murugesan ^a   Menon, K M J ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA HYDROXY DELTA5 STEROID DEHYDROGENASE; ANDROGEN; CHORIONIC GONADOTROPIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FORSKOLIN; INITIATION FACTOR 4E; LUTEINIZING HORMONE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MESSENGER RNA; PROTEIN; RAPAMYCIN; S6 KINASE; SMALL INTERFERING RNA; STAR PROTEIN; STEROID 17ALPHA MONOOXYGENASE; UNCLASSIFIED DRUG;

ANDROGEN SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RAT; SIGNAL TRANSDUCTION; STEROIDOGENESIS; THECA CELL;

ANDROGENS; ANDROSTENEDIONE; ANIMALS; CELLS, CULTURED; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CHORIONIC GONADOTROPIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENZYME INDUCTION; EUKARYOTIC INITIATION FACTOR-4E; FEMALE; FORSKOLIN; GENE KNOCKDOWN TECHNIQUES; LUTEINIZING HORMONE; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOMAL PROTEIN S6 KINASES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SIROLIMUS; STEROID 17-ALPHA-HYDROXYLASE; THECA CELLS; TOR SERINE-THREONINE KINASES;

EUKARYOTA; MAMMALIA;

EID: 84866995270     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2012-1106     Document Type: Article

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