Ovarian enzyme activities in women with polycystic ovary syndrome

Fertility and Sterility

Volumn 86, Issue SUPPL. 1, 2006, Pages

  Magoffin, Denis A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

androgen production; Ovary; PCOS; steroidogenesis

Indexed keywords

AROMATASE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME P450; STEROID 5ALPHA REDUCTASE;

ARTICLE; CELL CULTURE; ENZYME ACTIVITY; GRANULOSA CELL; HUMAN; OVARY FOLLICLE; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEROIDOGENESIS; THECA CELL; TISSUE CULTURE; UPREGULATION;

ADULT; AROMATASE; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; FEMALE; GRANULOSA CELLS; HUMANS; OVARY; POLYCYSTIC OVARY SYNDROME; TESTOSTERONE 5-ALPHA-REDUCTASE; THECA CELLS;

EID: 33745185834     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2006.03.015     Document Type: Article

References (5)

1. Jakimiuk A.J., Weitsman S.R., Navab A., and Magoffin D.A. Luteinizing hormone receptor, steroidogenesis acute regulatory protein and steroidogenic enzyme messenger ribonucleic acids are overexpressed in theca and granulosa cells from polycystic ovaries. J Clin Endocrinol Metab 86 (2001) 1318-1323
2. Zhang L., Rodriguez H., Ohno S., and Miller W.L. Serine phosphorylation of human P450c17 increases 17,20-lyase activity. implications for adrenarche and the polycystic ovary syndrome. Proc Natl Acad Sci U S A 92 (1995) 10619-10623
3. Jakimiuk A.J., Weitsman S.R., Brzechffa P.R., and Magoffin D.A. Aromatase messenger ribonucleic acid expression in individual follicles from polycystic ovaries. Mol Hum Reprod 4 (1998) 1-8
4. Jakimiuk A.J., Weitsman S.R., and Magoffin D.A. 5α-reductase activity in women with polycystic ovary syndrome. J Clin Endocrinol Metab 84 (1999) 2414-2418
5. Agarwal S.K., Judd H.L., and Magoffin D.A. A mechanism for suppression of estrogen production in women with polycystic ovary syndrome. J Clin Endocrinol Metab 81 (1996) 3686-3691