Functional status and relationships of melanocortin 1 receptor signaling to the cAMP and extracellular signal-regulated protein kinases 1 and 2 pathways in human melanoma cells

International Journal of Biochemistry and Cell Biology

Volumn 44, Issue 12, 2012, Pages 2244-2252

  Herraiz, Cecilia ^a   Journé, Fabrice ^b   Ghanem, Ghanem ^b   Jiménez Cervantes, Celia ^a,c   García Borrón, José C ^a,c  

^a UNIVERSITY OF MURCIA   (Spain)

^b FREE UNIVERSITY OF BRUSSELS   (Belgium)

^c Instituto Murciano de Investigación Biomédica IMIB   (Spain)

Author keywords

cAMP; ERK; MC1R variants; Melanocortin 1 receptor; Melanoma; Signaling

Indexed keywords

CYCLIC AMP; FORSKOLIN; MELANOCORTIN 1 RECEPTOR; MELANOCORTIN RECEPTOR AGONIST; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME BINDING; ENZYME INHIBITION; GENOTYPE; HUMAN; HUMAN CELL; MELANOMA CELL; MUTATION; NUCLEOTIDE METABOLISM; NUCLEOTIDE SEQUENCE; ONCOGENE N RAS; PHARMACOLOGICAL BLOCKING; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WILD TYPE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CELL LINE, TUMOR; CYCLIC AMP; GTP PHOSPHOHYDROLASES; HUMANS; MAP KINASE SIGNALING SYSTEM; MELANOMA; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS B-RAF; RECEPTOR, MELANOCORTIN, TYPE 1; SECOND MESSENGER SYSTEMS;

EID: 84866983432     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.09.008     Document Type: Article

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