Tandem BRAF mutations in primary invasive melanomas

Journal of Investigative Dermatology

Volumn 122, Issue 5, 2004, Pages 1245-1250

  Thomas, Nancy E ^a,b   Alexander, Audrey ^a,c   Edmiston, Sharon N ^a,c   Parrish, Eloise ^a,c   Millikan, Robert C ^a,c   Berwick, Marianne ^d   Groben, Pamela ^b   Ollila, David W ^a,b   Mattingly, Dianne ^a,c   Conway, Kathleen ^a,c  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c IL   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

BRAF; Melanoma; Tandem mutation

Indexed keywords

DNA;

ADULT; AGED; CANCER GROWTH; CLINICAL ARTICLE; CONTROLLED STUDY; EXON; FEMALE; GENE MUTATION; HUMAN; HUMAN TISSUE; INVASIVE CARCINOMA; MALE; MELANOMA; MOLECULAR CLONING; NUCLEIC ACID BASE SUBSTITUTION; ONCOGENE; ONCOGENE BRAF; PRIORITY JOURNAL; REVIEW; SEQUENCE ANALYSIS; SKIN CARCINOGENESIS;

EID: 2442486432     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0022-202X.2004.22523.x     Document Type: Article

References (18)

1. Armstrong BK, Kricker A: The epidemiology of UV induced skin cancer. J Photochem Photobiol 63:8-18, 2001
2. Brose MS, Volpe P, Feldman M, et al: BRAF and RAS mutations in human lung cancer and melanoma. Cancer Res 62:6997-7000, 2002
3. Davies H, Bignell GR, Cox C, et al: Mutations of the BRAF gene in human cancer. Nature (Lond) 417:949-954, 2002
4. Dong J, Phelps RG, Qiao R, Yao S, Benard O, Ronai Z, Aaronson SA: Braf oncogenic mutations correlate with progression rather than initiation of human melanomas. Cancer Res 63:3883-3885, 2003
5. Elwood MJ, Jospon J: Melanoma and sun exposure: An overview of published studies. Int J Cancer 73:198-203, 1997
6. Gorden A, Osman I, Gai W, et al: Analysis of BRAF and N-RAS mutations in metastatic melanoma tissues. Cancer Res 63:3955-3957, 2003
7. Hingorani SR, Jacobetz MA, Robertson GP, Herlyn M, Tuveson DA: Suppression of BRAFV599E in human melanoma abrogates transformation. Cancer Res 63:5198-5202, 2003
8. Jemal A, Murray T, Samuels A, Ghafoor A, Ward E, Thun MJ: Cancer statistics, 2003. CA Cancer J Clin 53:5-26, 2003
9. Johnson LN, Lowe ED, Noble ME, Owen DJ: The eleventh Datta lecture. The structural basis for substrate recognition and control by protein kinases. FEBS Lett 430:1-11, 1998
10. Kumar R, Angelini S, Czene K, Sauroja I, Hahka-Kemppinen M, Pyrhonen S, Hemminki K: BRAF mutations in metastatic melanoma: A possible association with clinical outcome. Clin Cancer Res 9:3362-3368, 2003
11. Lee DH, O'Connor TR, Pfeifer GP: Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG → TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells. Nucleic Acids Res 30:3566-3573, 2002
12. Oller AR, Gijalkowska IJ, Dunn RL, Schaaper RM: Transcription-repair coupling determines the strandedness of ultraviolet mutagenesis in Escherichia coli. Proc Natl Acad Sci USA 89:11036-11040, 1992
13. Pollock PM, Harper UL, Hansen KS, et al: High frequency of BRAF mutations in nevi. Nat Genet 33:19-20, 2003
14. Tannapfel A, Sommerer F, Benicke M, et al: Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma. Gut 52:706-712, 2003
15. Uribe P, Wistuba II, González S: BRAF mutation: A frequent event in benign, atypical, and malignant melanocytic lesions of the skin. Amer J Dermatopath 25:365-370, 2003
16. Wang L, Cunningham JM, Winters JL, et al: BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair. Cancer Res 63:5209-5212, 2003
17. Yuen ST, Davies H, Chan TL, et al: Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia. Cancer Res 62:6451-6455, 2002
18. Zhang BH, Guan KL: Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601. EMBO J 19:5429-5439, 2000