Human melanocytes expressing MC1R variant alleles show impaired activation of multiple signaling pathways

Peptides

Volumn 28, Issue 12, 2007, Pages 2387-2396

  Newton, Richard A ^a   Roberts, Donald W ^a,b   Leonard, J Helen ^b   Sturm, Richard A ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

cAMP; Melanocortin 1 receptor; Melanocyte; p38; Signaling; UV

Indexed keywords

ALPHA INTERMEDIN; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; INTERMEDIN DERIVATIVE; MELANOCORTIN 1 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38;

ALLELE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MELANOCYTE; ONCOGENE C FOS; PHENOTYPE; PIGMENTATION; PRIORITY JOURNAL; PROTEIN BINDING; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ULTRAVIOLET IRRADIATION; WILD TYPE;

ALLELES; ALPHA-MSH; CELLS, CULTURED; CYCLIC AMP; HAIR COLOR; HUMANS; MELANOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTOR, MELANOCORTIN, TYPE 1; RNA, MESSENGER; SIGNAL TRANSDUCTION; SKIN PIGMENTATION; ULTRAVIOLET RAYS; VARIATION (GENETICS);

EID: 36148947881     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2007.10.003     Document Type: Article

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