Bmi1 Is Required for Hepatic Progenitor Cell Expansion and Liver Tumor Development

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Fan, Lingling ^a,b   Xu, Chuanrui ^b   Wang, Chunmei ^a   Tao, Junyan ^a   Ho, Coral ^a   Jiang, Lijie ^a   Gui, Bing ^a   Huang, Shiang ^b   Evert, Matthias ^c   Calvisi, Diego F ^c   Chen, Xin ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARF PROTEIN; BMI1 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; MESSENGER RNA; PROTEIN KINASE B; RAS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BMI1 GENE; CELL PROLIFERATION; CONTROLLED STUDY; GENE DELETION; GENE FUNCTION; GENE LOCUS; GENE LOSS; HISTOPATHOLOGY; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LIVER CARCINOGENESIS; LIVER TUMOR; LIVER WEIGHT; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; ONCOGENE; OXIDATIVE STRESS; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; STEM CELL EXPANSION; UPREGULATION;

ANIMALS; CARCINOGENS; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CHOLANGIOCARCINOMA; CYCLIN-DEPENDENT KINASE INHIBITOR P16; GENE EXPRESSION; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; POLYCOMB REPRESSIVE COMPLEX 1; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PYRIDINES; RAS PROTEINS; STEM CELLS;

MUS;

EID: 84866981249     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046472     Document Type: Article

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