Phosphatidylethanolamine binding is a conserved feature of cyclotide-membrane interactions

Journal of Biological Chemistry

Volumn 287, Issue 40, 2012, Pages 33629-33643

  Henriques, Sónia Troeira ^a,b   Huang, Yen Hua ^a   Castanho, Miguel A R B ^b   Bagatolli, Luis A ^d   Sonza, Secondo ^c,e   Tachedjian, Gilda ^c,e   Daly, Norelle L ^a,f   Craik, David J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF LISBON   (Portugal)

^c BURNET INSTITUTE   (Australia)

^d UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^e MONASH UNIVERSITY   (Australia)

^f JAMES COOK UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL POTENCY; CELL TYPES; COMPLEX STRUCTURE; CYCLIC PEPTIDES; CYCLOTIDES; DRUG DESIGN; HEAD GROUPS; LIPID-BINDING PROTEINS; MEMBRANE AFFINITY; MIRROR IMAGES; MODE OF ACTION; PEPTIDE DRUGS; PHOSPHATIDYLETHANOLAMINE; POTENTIAL APPLICATIONS; RED BLOOD CELL; SEQUENCE DIVERSITY; STRUCTURAL MOTIFS;

BINDING ENERGY; BIOACTIVITY; CELL MEMBRANES; CYTOLOGY; PEPTIDES; PHOSPHOLIPIDS;

MEMBRANES;

CYCLOTIDE; CYCLOTIDE KB1; CYCLOTIDE KB2; CYCLOTIDE KB5; CYCLOTIDE KB6; CYCLOTIDE KB7; CYCLOTIDE KB8; CYCLOTIDE KB9; CYCLOVIOLACIN O2; PHOSPHATIDYLETHANOLAMINE; TRICYCLON A; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBACTERIAL ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CELL TYPE; CELL VACUOLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; DRUG TARGETING; ESCHERICHIA COLI; GROWTH INHIBITION; HEMOLYSIS; HUMAN IMMUNODEFICIENCY VIRUS 1; MEMBRANE BINDING; MEMBRANE DAMAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN LIPID INTERACTION; PROTEIN STRUCTURE; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; CELL MEMBRANE; CHEMISTRY, PHARMACEUTICAL; CONSERVED SEQUENCE; CYCLOTIDES; DRUG DESIGN; ERYTHROCYTES; HEMOLYSIS; HUMANS; LIPID BILAYERS; LIPIDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; PEPTIDES; PHOSPHATIDYLETHANOLAMINES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SURFACE PLASMON RESONANCE;

EID: 84866943858     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.372011     Document Type: Article

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