Processing of a 22 kDa precursor protein to produce the circular protein tricyclon A

Structure

Volumn 13, Issue 5, 2005, Pages 691-701

  Mulvenna, Jason P ^a   Sando, Lillian ^a   Craik, David J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; PROTEIN P22; PROTEIN PRECURSOR; TRICYCLON A; UNCLASSIFIED DRUG; VEGETABLE PROTEIN;

ARTICLE; CONTROLLED STUDY; CYCLIZATION; HEMOLYSIS; HYDROPHOBICITY; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE;

AMINO ACID SEQUENCE; CYCLOTIDES; ERYTHROCYTES; HEMOLYSIS; HUMANS; MOLECULAR SEQUENCE DATA; OLDENLANDIA; PEPTIDES, CYCLIC; PLANT PROTEINS; PROTEIN CONFORMATION; PROTEIN PRECURSORS;

EID: 18944396316     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2005.02.013     Document Type: Article

References (49)

1. D.G. Barry, N.L. Daly, R.J. Clark, L. Sando, and D.J. Craik Linearization of a naturally occurring circular protein maintains structure but eliminates hemolytic activity Biochemistry 42 2003 6688 6695
2. D.G. Barry, N.L. Daly, H.R. Bokesch, K.R. Gustafson, and D.J. Craik Solution structure of the cyclotide palicourein: implications for the development of a pharmaceutical framework Structure 12 2004 85 94
3. L. Braunschweiler, and R.R. Ernst Coherence transfer by isotropic mixing: application to proton correlation spectroscopy J. Magn. Reson. 53 1983 521 528
4. J.C. Brown, N.A. Jolliffe, L. Frigerio, and L.M. Roberts Sequence-specific, Golgi-dependent vacuolar targeting of castor bean 2S albumin Plant J. 36 2003 711 719
5. A.T. Brunger, P.D. Adams, and L.M. Rice New applications of simulated annealing in X-ray crystallography and solution NMR Structure 5 1997 325 336
6. P. Bulet, R. Stocklin, and L. Menin Anti-microbial peptides: from invertebrates to vertebrates Immunol. Rev. 198 2004 169 184
7. J.A. Camarero, D. Fushman, S. Sato, I. Giriat, D. Cowburn, D.P. Raleigh, and T.W. Muir Rescuing a destabilized protein fold through backbone cyclization J. Mol. Biol. 308 2001 1045 1062
8. M.L. Colgrave, and D.J. Craik Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: the importance of the cyclic cystine knot Biochemistry 43 2004 5965 5975
9. D.J. Craik Plant cyclotides: circular, knotted peptide toxins Toxicon 39 2001 1809 1813
10. D.J. Craik, N.L. Daly, T. Bond, and C. Waine Plant cyclotides: a unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif J. Mol. Biol. 294 1999 1327 1336
11. D.J. Craik, N.L. Daly, and C. Waine The cystine knot motif in toxins and implications for drug design Toxicon 39 2001 43 60
12. D.J. Craik, S. Simonsen, and N.L. Daly The cyclotides: novel macrocyclic peptides as scaffolds in drug design Curr. Opin. Drug Discov. Devel. 5 2002 251 260
13. D.J. Craik, N.L. Daly, J. Mulvenna, M.R. Plan, and M. Trabi Discovery, structure and biological activities of the cyclotides Curr. Protein Pept. Sci. 5 2004 297 315
14. N.L. Daly, A. Koltay, K.R. Gustafson, M.R. Boyd, J.R. Casas-Finet, and D.J. Craik Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity J. Mol. Biol. 285 1999 333 345
15. N.L. Daly, S. Love, P.F. Alewood, and D.J. Craik Chemical synthesis and folding pathways of large cyclic polypeptides: studies of the cystine knot polypeptide kalata B1 Biochemistry 38 1999 10606 10614
16. S. Deechongkit, and J.W. Kelly The effect of backbone cyclization on the thermodynamics of β-sheet unfolding: stability optimization of the PIN WW domain J. Am. Chem. Soc. 124 2002 4980 4986
17. W.L. DeLano The PyMOL Molecular Graphics System http://www.pymol.org 2002
18. J.E. Dombrowski, M.R. Schroeder, S.Y. Bednarek, and N.V. Raikhel Determination of the functional elements within the vacuolar targeting signal of barley lectin Plant Cell 5 1993 587 596
19. Y. Dou, P.F. Baisnee, G. Pollastri, Y. Pecout, J. Nowick, and P. Baldi ICBS: a database of interactions between protein chains mediated by β-sheet formation Bioinformatics 20 2004 2767 2777
20. J.L. Dutton, R.F. Renda, C. Waine, R.J. Clark, N.L. Daly, C.V. Jennings, M.A. Anderson, and D.J. Craik Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteins J. Biol. Chem. 279 2004 46858 46867
21. L. Frigerio, M. de Virgilio, A. Prada, F. Faoro, and A. Vitale Sorting of phaseolin to the vacuole is saturable and requires a short C-terminal peptide Plant Cell 10 1998 1031 1042
22. L. Frigerio, N.A. Jolliffe, A. Di Cola, D.H. Felipe, N. Paris, J.M. Neuhaus, J.M. Lord, A. Ceriotti, and L.M. Roberts The internal propeptide of the ricin precursor carries a sequence-specific determinant for vacuolar sorting Plant Physiol. 126 2001 167 175
23. Goddard, T.D., and Kneller, D.G. (2005). SPARKY 3 (computer program). University of California, San Francisco.
24. C. Griesinger, O.W. Sorensen, and R.R. Ernst Practical aspects of the E-COSY technique, measurement of scalar spin-spin coupling constants in peptides J. Magn. Reson. 75 1987 474 492
25. P. Guntert, C. Mumenthaler, and K. Wuthrich Torsion angle dynamics for NMR structure calculation with the new program DYANA J. Mol. Biol. 273 1997 283 298
26. K.R. Gustafson, R.C. Sowder, L.E. Henderson, I.C. Parsons, Y. Kashman, J.H. Cardellina, J.B. McMahon, R.W. Buckheit, L.K. Pannell, and M.R. Boyd Circulins A and B: novel HIV-inhibitory macrocyclic peptides from the tropical tree Chassalia parvifolia J. Am. Chem. Soc. 116 1994 9337 9338
27. E.G. Hutchinson, and J.M. Thornton PROMOTIF: a program to identify and analyze structural motifs in proteins Protein Sci. 5 1996 212 220
28. J. Jeener, B.H. Meier, P. Bachmann, and R.R. Ernst Investigation of exchange processes by two dimensional NMR spectroscopy J. Chem. Phys. 71 1979 4546 4553
29. C. Jennings, J. West, C. Waine, D. Craik, and M. Anderson Biosynthesis and insecticidal properties of plant cyclotides: the cyclic knotted proteins from Oldenlandia affinis Proc. Natl. Acad. Sci. USA 98 2001 10614 10619
30. R. Koradi, M. Billeter, and K. Wuthrich MOLMOL: a program for display and analysis of macromolecular structures J. Mol. Graph. 14 1996 51 55
31. J.P. Linge, and M. Nilges Influence of non-bonded parameters on the quality of NMR structures: a new force field for NMR structure calculation J. Biomol. NMR 13 1999 51 59
32. D. Marion, and K. Wuthrich Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins Biochem. Biophys. Res. Commun. 113 1983 967 974
33. L. Martin, F. Stricher, D. Misse, F. Sironi, M. Pugniere, P. Barth, R. Prado-Gotor, I. Freulon, X. Magne, and C. Roumestand Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes Nat. Biotechnol. 21 2003 71 76
34. K. Matsuoka, and K. Nakamura Large alkyl side-chains of isoleucine and leucine in the NPIRL region constitute the core of the vacuolar sorting determinant of sporamin precursor Plant Mol. Biol. 41 1999 825 835
35. K. Muntz, and A.D. Shutov Legumains and their functions in plants Trends Plant Sci. 7 2002 340 344
36. J.M. Neuhaus, M. Pietrzak, and T. Boller Mutation analysis of the C-terminal vacuolar targeting peptide of tobacco chitinase: low specificity of the sorting system, and gradual transition between intracellular retention and secretion into the extracellular space Plant J. 5 1994 45 54
37. M. Piotto, V. Saudek, and V. Sklenar Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions J. Biomol. NMR 2 1992 661 665
38. M. Rance, O.W. Sorensen, G. Bodenhausen, G. Wagner, R.R. Ernst, and K. Wuthrich Improved spectral resolution in COSY 1H NMR spectra of proteins via double quantum filtering Biochem. Biophys. Res. Commun. 27 1983 157 162
39. K.J. Rosengren, N.L. Daly, M.R. Plan, C. Waine, and D.J. Craik Twists, knots, and rings in proteins. Structural definition of the cyclotide framework J. Biol. Chem. 278 2003 8606 8616
40. B. Rost, and C. Sander Prediction of protein secondary structure at better than 70% accuracy J. Mol. Biol. 232 1993 584 599
41. G. Saalbach, M. Rosso, and U. Schumann The vacuolar targeting signal of the 2S albumin from Brazil nut resides at the C terminus and involves the C-terminal propeptide as an essential element Plant Physiol. 112 1996 975 985
42. O. Saether, D.J. Craik, I.D. Campbell, K. Sletten, J. Juul, and D.G. Norman Elucidation of the primary and three-dimensional structure of the utertonic polypeptide kalata B1 Biochemistry 34 1995 4147 4158
43. T. Schopke, M.I. Hasan Agha, R. Kraft, A. Otto, and K. Hiller H ämolytisch aktive komponenten aus Viola tricolor l. und Viola arvensis Murray. Sci. Pharm. 61 1993 145 153
44. J.P. Tam, Y.A. Lu, J.L. Yang, and K.W. Chiu An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides Proc. Natl. Acad. Sci. USA 96 1999 8913 8918
45. H.W. Tedford, J.I. Fletcher, and G.F. King Functional significance of the β-hairpin in the insecticidal neurotoxin ω-Atracotoxin-hv1a J. Biol. Chem. 276 2001 26568 26576
46. M. Trabi, and D.J. Craik Circular proteins - no end in sight Trends Biochem. Sci. 27 2002 132 138
47. M. Trabi, and D.J. Craik Tissue-specific expression of head-to-tail cyclized miniproteins in Violaceae and structure determination of the root cyclotide Viola hederacea root cyclotide1 Plant Cell 16 2004 2204 2216
48. K.M. Witherup, M.J. Bogusky, P.S. Anderson, H. Ramjit, R.W. Ransom, T. Wood, and M. Sardana Cyclopsychotride A, a biologically active, 31-residue cyclic peptide isolated from Psychotria longipes J. Nat. Prod. 57 1994 1619 1625
49. K. Wuthrich, M. Billeter, and W. Braun Pseudo-structures for the 20 common amino acids for use in studies of protein conformations by measurements of intramolecular proton-proton distance constraints with nuclear magnetic resonance J. Mol. Biol. 169 1983 949 961