Transcriptional Repression of Hox Genes by C. elegans HP1/HPL and H1/HIS-24

PLoS Genetics

Volumn 8, Issue 9, 2012, Pages

  Studencka, Maja ^a   Wesołowski, Radosław ^a,d   Opitz, Lennart ^b   Salinas Riester, Gabriela ^b   Wisniewski, Jacek R ^c   Jedrusik Bode, Monika ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^d JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

HETEROCHROMATIN PROTEIN 1; HISTONE; HISTONE 24; HISTONE H1; HOX PROTEIN; HPL 1 PROTEIN; HPL 2 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; CELL FATE; CELL STRUCTURE; CONTROLLED STUDY; EGL 5 GENE; GENE; GENE EXPRESSION REGULATION; GENE LOCUS; GENE MUTATION; GENE REPRESSION; GONAD DEVELOPMENT; MAB 5 GENE; MATING; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REPRODUCTION; SOMATIC CELL; TAIL; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION; UPREGULATION; VULVA;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CHROMOSOMAL PROTEINS, NON-HISTONE; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HOMEODOMAIN PROTEINS; MALE; METHYLATION; MUTATION; TAIL; TRANSCRIPTION FACTORS; VULVA;

ANIMALIA; CAENORHABDITIS ELEGANS; MAMMALIA; MUS; NEMATODA;

EID: 84866933815     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002940     Document Type: Article

References (47)

1. Shen X, Gorovsky MA, (1996) Linker histone H1 regulates specific gene expression but not global transcription in vivo. Cell 86: 475-83.
2. Hellauer K, Sirard E, Turcotte B, (2001) Decreased expression of specific genes in yeast cells lacking histone H1. J Biol Chem 276: 13587-92.
3. Gilbert N, Boyle S, Sutherland H, de Las Heras J, Allan J, et al. (2003) Formation of facultative heterochromatin in the absence of HP1. EMBO J 22: 5540-5550.
4. Laybourn PJ, Kadonaga JT, (1991) Role of nucleosomal cores and histone H1 in regulation of transcription by RNA polymerase II. Science 254: 238-245.
5. Verschure PJ, van der Kraan I, de Leeuw W, van der Vlag J, Carpenter AE, et al. (2005) In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation. Mol Cell Biol 25: 4552-64.
6. Daujat S, Zeissler U, Waldmann T, Happel N, Schneider R, (2005) HP1 binds specifically to Lys26-methylated histone H1.4, whereas simultaneous Ser27 phosphorylation blocks HP1 binding. J Biol Chem 280: 38090-5.
7. Sirotkin AM, Edelmann W, Cheng G, Klein-Szanto A, Kucherlapati R, et al. (1995) Mice develop normally without the H10 linker histone. Proc Natl Acad Sci USA 92: 6434-6438.
8. Sancho M, Diani E, Beato M, Jordan A, (2008) Depletion of Human Histone H1 Variants Uncovers Specific Roles in Gene Expression and Cell Growth. PLoS Genet 4 (10) (): e1000227.
9. Filesi I, Cardinale A, van der Sar S, Cowell IG, Singh PB, et al. (2002) Loss of heterochromatin protein 1 (HP1) chromodomain function in mammalian cells by intracellular antibodies causes cell death. J Cell Sci 115: 1803-1813.
10. Aucott R, Bullwinkel J, Yu Y, Shi W, Billur M, et al. (2008) HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions. J Cell Biol 183: 597-606.
11. Fan Y, Nikitina T, Zhao J, Fleury TJ, Bouhassira EE, et al. (2005) Histone H1 depletion in mammals alters global chromatin structure but causes specific changes in gene regulation. Cell 123: 1199-212.
12. Fan Y, Nikitina T, Morin-Kensicki EM, Zhao J, Magnuson TR, et al. (2003) H1 linker histones are essential for mouse development and affect nucleosome spacing in vivo. Mol Cell Biol 23: 4559-72.
13. Maclean JA, Bettegowda A, Kim BJ, Lou CH, Yang SM, et al. (2011) The rhox homeobox gene cluster is imprinted and selectively targeted for regulation by histone H1 and DNA methylation. Mol Cell Biol 31: 1275-87.
14. Jedrusik MA, Schulze E, (2001) Single histone H1 isoform (H1.1) is essential for chromatin silencing and germline development in Caenorhabditis elegans. Development 128: 1069-80.
15. Couteau F, Guerry F, Muller F, Palladino F, (2002) A heterochromatin protein 1 homologue in Caenorhabditis elegans acts in germline and vulval development. EMBO Rep 3: 235-41.
16. Studencka M, Konzer A, Moneron G, Wenzel D, Opitz L, et al. (2011) Novel roles of C. elegans heterochromatin protein HP1 and linker histone in the regulation of innate immune gene expression. Mol Cell Biol 32: 251-65.
17. Schott S, Coustham V, Simonet T, Bedet C, Palladino F, (2006) Unique and redundant functions of C. elegans HP1 proteins in post-embryonic development. Dev Biol 298: 176-187.
18. Wirth M, Paap F, Fischle W, Wenzel D, Agafonov DE, et al. (2009) HIS-24 linker histone and SIR-2.1 deacetylase induce H3K27me3 in the Caenorhabditis elegans germ line. Mol Cell Biol 29: 3700-9.
19. Margueron R, Reinberg D, (2011) The Polycomb complex PRC2 and its mark in life. Nature 469: 343-9.
20. Gellon G, McGinnis W, (1998) Shaping animal body plans in development and evolution by modulation of Hox expression patterns. BioEssays 20: 116-125.
21. Levine SS, Weiss A, Erdjument-Bromage H, Shao Z, Tempst P, et al. (2002) The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans. Mol Cell Biol 22: 6070-8.
22. Aboobaker AA, Blaxter ML, (2003) Hox Gene Loss during Dynamic Evolution of the Nematode Cluster. Curr Biol 13: 37-40.
23. Ross JM, Zarkower D, (2003) Polycomb group regulation of Hox gene expression in C. elegans. Dev Cell 4: 891-901.
24. Zhang H, Azevedo RB, Lints R, Doyle C, Teng Y, et al. (2003) Global regulation of Hox gene expression in C. elegans by a SAM domain protein. Dev Cell 4: 903-15.
25. Zhang T, Sun Y, Tian E, Deng H, Zhang Y, et al. (2006) RNA-binding proteins SOP-2 and SOR-1 form a novel PcG-like complex in C. elegans. Development 133: 1023-33.
26. Jedrusik MA, Schulze E, (2007) Linker histone HIS-24 (H1.1) cytoplasmic retention promotes germ line development and influences histone H3 methylation in Caenorhabditis elegans. Mol Cell Biol 27: 2229-39.
27. Schott S, Ramos F, Coustham V, Palladino F, (2009) HPL-2/HP1 prevents inappropriate vulval induction in Caenorhabditis elegans by acting in both HYP7 and vulval precursor cells. Genetics 181: 797-801.
28. Salser SJ, Kenyon C, (1996) A C. elegans Hox gene switches on, off, on and off again to regulate proliferation, differentiation and morphogenesis. Development 122: 1651-1661.
29. Ferreira HB, Zhang Y, Zhao C, Emmons SW, (1999) Patterning of Caenorhabditis elegans posterior structures by the Abdominal-B homolog, egl-5. Dev Biol 207: 215-228.
30. Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, et al. (2002) Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 298: 1039-1043.
31. Cao R, Zhang Y, (2004) The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3. Curr Opin Genet Dev 14: 155-164.
32. Müller J, Hart CM, Francis NJ, Vargas ML, Sengupta A, et al. (2002) Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell 111: 197-208.
33. Holdeman R, Nehrt S, Strome S, (1998) MES-2, a maternal protein essential for viability of the germline in Caenorhabditis elegans, is homologous to a Drosophila Polycomb group protein. Development 125: 2457-2467.
34. Alami R, Fan Y, Pack S, Sonbuchner TM, Besse A, et al. (2003) Mammalian linker-histone subtypes differentially affect gene expression in vivo. Proc Natl Acad Sci U S A 100: 5920-5.
35. Sancho M, Diani E, Beato M, Jordan A, (2008) Depletion of human histone H1 variants uncovers specific roles in gene expression and cell growth. PLoS Genetics 4 (10) (): e1000227.
36. Koop R, Di Croce L, Beato M, (2003) Histone H1 enhances synergestic activation of the MMTV promoter in chromatin. EMBO Journal 22: 588-599.
37. Dialynas GK, Terjung S, Brown JP, Aucott RL, Baron-Luhr B, et al. (2007) Plasticity of HP1 proteins in mammalian cells. JSC 120: 3415-3424.
38. Li Y, Kirschmann DA, Wallrath LL, (2002) Does heterochromatin protein 1 always follow code? Proc Natl Acad Sci USA 99: 16462-16469.
39. Singh PB, Georgatos SD, (2002) HP1: facts, open questions, and speculation. J Struct Biol 140: 10-16.
40. Flueck C, Bartfai R, Volz J, Niederwieser I, Salcedo-Amaya AM, et al. (2009) Plasmodium falciparum heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors. PLoS Pathog 5 (9) (): e1000569.
41. Nielsen PR, Nietlispach D, Mott HR, Callaghan J, Bannister A, et al. (2002) Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9. Nature 416: 103-107.
42. Czermin B, Melfi R, McCabe D, Seitz V, Imhof A, et al. (2002) Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell 111: 185-196.
43. Brenner S, (1974) The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
44. Opitz L, Salinas-Riester G, Grade M, Jung K, Jo P, et al. (2010) Impact of RNA degradation on gene expression profiling. BMC Medical Genomics 3: 36.
45. Ercan S, Giresi PG, Whittle CM, Zhang X, Green RD, et al. (2007) X chromosome repression by localization of the C. elegans dosage compensation machinery to sites of transcription initiation. Nat Genet 39: 403-8.
46. Wysocka J, (2006) Identifying novel proteins recognizing histone modifications using peptide pull-down assay. Methods 40: 339-43.
47. Cheeseman IM, Desai A, (2005) A combined approach for the localization and tandem affinity purification of protein complexes from metazoans. Sci STKE 266, pp. pl1.